Genetic testing in breast cancer

Genetic testing in breast cancer

Genetic testing in breast cancer

Christina applegate

Introduction:

Hereditary Breast & Ovarian Cancer Syndrome (BRCA)

What is the purpose of our normal BRCA genes?

Background

Identification of high risk individuals

Genetic testing

Red Flags for Hereditary Breast and Ovarian Cancer Syndrome

Red Flags for Women & Men who do not have Cancer

Family history considerations:

Brca1 and brca2

Identifying brca 1/2 carriers:

Cancer risks:

Newer considerations:

NCcn guideline for management of brca 1/2 carrier:

Genetic Testing

Psychosocial considerations

Gina legislation

Summary:

Tp 53

Identifying Li Fraumeni Syndrome

Cancer risks in lfs

Cowden syndrome (phosphate and tensin homolog)

Other genetic mutations and breast cancer

Lynch syndrome and MYH associated polyposis

Categories of genes associated with hereditary and ovarian breast cancer

Rachel, age 40 no cancer

Rachels Test result

Rachel-- Ovarian Recommendations

Rachel Breast Recommendations

Rachel Family Recommendations

Heather, age 38

Heather

Heather

Conclusion: