Presented by Dr. Sudhakar Kokate Director PPRC, India Plants that cure Gastro Intestinal disorders (GID – Part I)
May 07, 2015
Presented by Dr. Sudhakar KokateDirector PPRC, India
Plantsthat cure
Gastro Intestinal disorders(GID – Part I)
Gastro-intestinal disorders (GID)
Include :Colitis
Constipation
Diarrhoea
Duodenal ulcers
Dyspepsia
Hyper-acidityPPRC/INDIA 01
In India
Plant species: 9500 Medicinal: 7500 Tribal medicinal plants: 300 For G.I. Disorders:
Bael Isabgol KurchiPale catechu Palas GingerShatavari Mandar Carrot
PPRC/INDIA 02
Around the World
Mexico: 65 plants to treat G.I. disorders(GID)
Thailand: 38 plants for GID Germany / France: Many herbs used as
prescription drug (Sale > $ 50bn……2010)
USA: $ 4 bn……1996 India: Drug market $1bn export of plant
crude drugs $ 80 mn PPRC/INDIA 03
Knowledge of Medi-plants
Dates back to 400 B.C.
First documented in Atharva Veda datesback to 4500-1500 B.C.
119 compounds with therapeutic valuehave been identified till date
Japanese pharmacopoeia 1993 contains123 active plants of which 29 are used inWestern medicine
PPRC/INDIA 04
Aconitum heterophyllum
PPRC/INDIA 05
Aconitum heterophyllum Habitat: Eastern Asia, Western Himalaya
Chemicals:- Astisine- Hetratisine- Histsine- Benzoyl-heterophyllum
It is employed in as a bitter tonic andanti-periodic
PPRC/INDIA 06
Aegle marmelos
PPRC/INDIA 07
Aegle marmelos Habitat: India, China, Sri Lanka, Burma,
Thailand
Chemicals:
Leaves: Alkaloid, Agelin, Sterol as V-sitosterol and Coumarins, Essential oilssuch as d-limonene
Bark: Aegelinin, Marmin
PPRC/INDIA 08
1/22/2014
Aegle marmelos Chemicals:
Fruit: Sugar, Tannin
Pulp: 2 furocoumarins-psoraen andMarmelosin
Properties: Astringent, Depurative,Alexeteric, Cooling, Anti-poison
PPRC/INDIA 09
Amphipterygium adstringens
PPRC/INDIA 10
Amphipterygium adstringensMost gastro-protective compounds:
3 epi-oleanolic acid
3 alpha-hydroxy mastica dienonic acid
Beta-sitosterol acid
PPRC/INDIA 11
Arnica montana
PPRC/INDIA 12
Arnica montana The plant is rich in Sesquiterpenes
It has advantage in states of depression,diarrhoea, dysentery, pneumonia, typhoidand excessive sweating
PPRC/INDIA 13
Asparagus adscendens
PPRC/INDIA 14
Asparagus adscendens Habitat: India – forests of Uttar Pradesh,
East Asia, Afghanistan, Himalayas, Iran
Chemical: Asparagine
Roots: Demulcent, Diaphoretic,Galactogogue, Stimulant are useful in thetreatment of Diarrhoea and dysentery
PPRC/INDIA 15
Calotropis gigantea
PPRC/INDIA 16
Calotropis gigantea Habitat: Sub-tropic & Tropic, India, Sri
Lanka, West Indies
Active principles: Saponins, Glucoside,Tannins, Lugeol, Flavonoids, Glycine,Butrin, Isobutrin, 3-o acetyl-calotropin
Root Bark extensively used for GID
PPRC/INDIA 17
Coriandrum sativum
PPRC/INDIA 18
Coriandrum sativum Coriander seed oil has anti-bacterial
property and is used for treating colic,neuralgia, rheumatism, diarrhoea,hemorrhoids, flatulence and abdominalpains
PPRC/INDIA 19
Curcuma longa
PPRC/INDIA 20
Curcuma longa Active principle: Curcumin
diferuoylemethane
PPRC/INDIA 21
Daucus carota
PPRC/INDIA 22
Daucus carota Chemicals: Lutenolin-7-glucoside,
Mevolonic acid, Pyrolidine daucine &Essential oils
Used in stomach & intestinal problems
Carrot soup remedy for diarrhoea
Properties: Anthelmintic, Carminative,Diuretic and Stimulant
PPRC/INDIA 23
Eugenia jambolana
PPRC/INDIA 24
Eugenia jambolana Seed powder effective in diarrhoea,
dysentery and diabetes
Habitat: India, Queensland
Chemicals: Oleanolic acid, Glucosideshowed significant reduction & G.I.motility
Fruit: Astringent, Stomachic, Carminative,Diuretic, Spleen enlargement, Chronicdiarrhoea & Urine retention PPRC/INDIA 25
Helicteres isora
PPRC/INDIA 26
Helicteres isora Chemicals:
- Phytosterol
- Hydroxy-carboxylic acid
- Phytolobotannins
Effective against G.I. disorders
PPRC/INDIA 27
Melissa officinalis
PPRC/INDIA 28
Melissa officinalis In Germany, Lemon balm is used as a
medicinal tea to treat G.I. disorders
Chemicals: 0.05% Volatile oil, Rosemaryacid
PPRC/INDIA 29
Ocimum sanctum
PPRC/INDIA 30
Ocimum sanctum Phyto-chemicals: Essential oils, Eugenol,
Methyl ether, Terbinene-4-01, Spigennins,Apigenin-7-0-glucuronide
Pharmacological action: Hypotensiveactivity, Inhibition of smooth musclecontraction induced by Acetylcholine,Carbachol and Histamine
PPRC/INDIA 31
Pueraria lobata
PPRC/INDIA 32
Puerata lobata In China, Japan; leaves, roots and shoots
are used for treating Alcoholism, Coldflu, G.I. disorders
Flowers and tubers are used for treatingFever, Cold, Diarrhoea, Dysentery andAcute intestinal ailments
PPRC/INDIA 33
Phyto-drugs* for curing G.I. Disorders
Drugs/Chemical Plant used
Aesculetin Frazinus rhychophylla
Andrographolide Andrographis paniculata
Berberine Berberis vulgaris
Hemsleyadin Hemsleya amabilis
Neoandrographolide Andrographis paniculata* Commercial PPRC/INDIA 34
Thank You !!