XXIV World Allergy Congress 14-17 October, 2015, Seoul Korea Function and Dysfunction of Skin Barrier Masayuki Amagai, M.D., Ph.D. Department of Dermatology, Keio University School of Medicine Laboratory for Skin Homeostasis, RCAI, RIKEN Center for Integrative Medical Sciences Plenary Session 3 Atopic Dermatitis : From Barrier to Inflammation Allergic rhinitis Asthma Food allergy Allergic disorders in different organs Allergic disorders Cutaneous sensitization Stratum Corenum Atopic dermatitis Cutaneous sensitization is the initial key step for many allergic disorders Skin external antigens Anaphylaxis SG2 SG3 SG1 Stratum Basale Stratum Spinosum Stratum Granulosum Proliferation Differentiation Cell Death Stratum Corneum Air-Liquid Barrier Tight Junction Liquid-Liquid Barrier Langerhans Cell Network Immune Barrier Reviewed by Kubo, Nagao and Amagai, J Clin Invest 2012 Epidermal Structure of Mammals Kubo et al, JEM 2009 Resting Langerhans cells stay under the TJ barrier
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Function and Dysfunction of Skin Barrier · 2015. 10. 9. · Department of Dermatology, Keio University School of Medicine Laboratory for Skin ... Integrative Medical Sciences Plenary
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XXIV World Allergy Congress 14-17 October, 2015, Seoul Korea
Function and Dysfunction of Skin Barrier
Masayuki Amagai, M.D., Ph.D. Department of Dermatology, Keio University School of Medicine Laboratory for Skin Homeostasis, RCAI, RIKEN Center for Integrative Medical Sciences
Plenary Session 3 Atopic Dermatitis : From Barrier to Inflammation
Allergic rhinitis
Asthma
Food allergy
Allergic disorders in different organs
Allergic disorders
Cutaneous sensitization
Stratum Corenum Atopic dermatitis
Cutaneous sensitization is the initial key step for many allergic disorders