From Acute to Chronic Pain Chronic Post Surgical Pain Prevention or Treatment Xavier Capdevila M.D.,Ph.D. Head of Department Department of Anesthesiology and Critical Care Medicine Lapeyronie University Hospital and Montpellier School of Medicine Montpellier , France
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From Acute to Chronic Pain Chronic Post Surgical Pain Prevention or Treatment
From Acute to Chronic Pain Chronic Post Surgical Pain Prevention or Treatment. Xavier Capdevila M.D.,Ph.D. Head of Department Department of Anesthesiology and Critical Care Medicine Lapeyronie University Hospital and Montpellier School of Medicine Montpellier , France. - PowerPoint PPT Presentation
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From Acute to Chronic PainChronic Post Surgical Pain Prevention or Treatment
Xavier Capdevila M.D.,Ph.D.Head of Department
Department of Anesthesiology and Critical Care MedicineLapeyronie University Hospital and Montpellier School of Medicine
Montpellier , France
Pain physiopathology: are we too simplistics???
SII
Insula (emotivity)
Nucleus accumbens
(awakeness)
Cerebellum (motivation)
Thalamus
SI
Pain physiopathology: complex systems!!!
No BrainNo Pain
Pain physiopathology: are we too simplistics???
ASA 2008, d’après J.Eisenach, RCL 123
Transition … from acute to chronic pain
Transition … from acute to chronic pain
Fonctional Imagery
Many hemispheric regions are activated during painful stimulation, and particularly at the controlateral level (orange areas).
Neuropathic pain (pain without stimulus) implies a lower thresholds and involves the same pathway as Schwann cells, cells from dorsal root ganglia, theimmune system, microglia and spinal astrocytes.
Glial cells are the inflammatory cells of the central nervous system