For sophomores and juniors interested in medical school at: • A visit by Dr. Jim Stallworth and other guests from USC School of Medicine in Columbia, SC. • In RMSC 122 (The Pit) starting at 6:30pm, Tuesday Nov 13 th . • Presentation and discussion on admissions and opportunities.
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For sophomores and juniors interested in medical school at: A visit by Dr. Jim Stallworth and other guests from USC School of Medicine in Columbia, SC.
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For sophomores and juniors interested in medical school at:
• A visit by Dr. Jim Stallworth and other guests from USC School of Medicine in Columbia, SC.
• In RMSC 122 (The Pit) starting at 6:30pm, Tuesday Nov 13th.
• Presentation and discussion on admissions and opportunities.
Abstracts and Test 2• Earn up to 5 points for Test # 2 based on
topics of Frog Heart Lab:– Regulation of pacemaker cells by
Mean Arterial Pressure = Cardiac Output x Total Peripheral Resistance
MAP = (HR x SV) x TPR
S 14
Who Cares?Hemorrhage Diagram from memory on Friday November 30th.
Name _________________________________________ On the back side of this page, create a diagram for the following. Your response must be confined to the reverse side of this page and you must write legibly. Your response will count 15-20% of the grade on Test 3 and should require no more than 15 minutes to complete at the beginning of class on Friday November 30th. Beginning with a loss of about 1 liter of blood from a vein, diagram the early events associated with hemorrhage and the negative feedback responses to hemorrhage in a well-organized diagram. Write legibly! Completeness, accuracy, and detail, together with the proper sequence earn maximal points. The following abbreviations can be used: AI, AII, JGA, mAChR, Hct, Q, SV, EF, RBC, HR, EDV, ACh, ANH, ADH, CO, TPR, EPO, VR, MAP, EPI, NE, SAN, aAdR , bAdR, Symp (sympathetic), Parasymp (parasympathetic), PV, r (radius), Pc, fAP (frequency of action potentials.) Any other abbreviations must be defined. "If in doubt, write it out!" Use single headed arrows (→) to indicate sequential relationships and doubled-stemmed arrows to indicate increases or decreases.
Pressure gradients in systemic vessels
Velocity in systemic vessels
Why is velocity slowest in capillaries and venules?
Flow =ml/min = Riders/min past a locationVelocity = m/sec for each rider
Velocity slows for exchange
Diameter of systemic vessels by type
Cumulative cross sectional area of vessels by type
Why is velocity slowest in capillaries and venules?
Properties of Blood Vessels
• Arteries
• Arterioles
• Capillaries
• Venules
• Veins
Elastic, low compliance, large diameter, low resistance vessels
Variable Resistance vessels
Exchange
Capacitance vessels, high compliance, low pressure, valves for unidirectional flow
All vessels and heart chambers lined with ENDOTHELIAL cells (simple squamous)
Wall = simple squamous endothelium
No smooth muscle; cannot change diameter
S 1
Fig. 12.30
Elastic recoil of stretched arterial walls during ventricular systole maintains arterial pressure during diastole as blood drains into arterioles.
Point of Confusion: Smooth muscles in arterial walls DO NOT rhythmically contract, do not pump!
Atherosclerosis
S 4
Stretching elastic connective tissue
Recoil of elastic connective tissue
Elastic recoil maintains internal pressure without expending energy
Arteries are a pressure reservoir to maintain pressure between during ventricular diastole and to keep blood flowing to arterioles during diastole.
Arteries and Arterial PressureMean Arterial Pressure
ArterioleArterioles have two main functions: 1) regulate flow to tissues and organs and 2) responsible for Total Peripheral Resistance which influences Mean Arterial Pressure.