EndoTrap ® affinity chromatography for highly specific and efficient endotoxin (LPS) removal EndoTrap ® The EndoTrap ® ligand is a highly LPS-specific, completely non-toxic protein derived from bacteriophages. EndoTrap ® removes endotoxins (lipopolysaccharides/LPS) from aqueous solutions of a wide range of samples such as proteins, antibodies, vaccines, nucleic acids, buffers and cell extracts with excellent sample recovery rates. EndoTrap ® can be used in column (gravity flow) or batch mode and is suitable for up-scaling on fully automated liquid-chromatographic systems. EndoTrap ® features • Best-in-class endotoxin binding capacity of 5,000,000 EU/ml • Removes more than 99.99%* of LPS • Excellent sample recovery rate > 95%* • Non-toxic phage-derived ligand, no cytotoxic effects • Re-use more than 10 times • Available in large quantities for up-scaling in biopharmaceutical processes *Measured values for BSA, MAK 33 (monoclonal antibody) and POD (peroxidase) with EndoTrap HD ® . 02.01.4 Endotoxin removal system Removal rate > 99.99%
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EndoTrap® affinity chromatography for highlyspecific and efficient endotoxin (LPS) removal
EndoTrap®
The EndoTrap® ligand is a highly LPS-specific, completely non-toxic protein derived from bacteriophages.EndoTrap® removes endotoxins (lipopolysaccharides/LPS) from aqueous solutions of a wide range of samples such as proteins, antibodies, vaccines, nucleic acids, buffers and cell extracts with excellent sample recovery rates.
EndoTrap® can be used in column (gravity flow) or batch mode and is suitable for up-scaling on fully automated liquid-chromatographic systems.
EndoTrap® features • Best-in-class endotoxin binding capacity of 5,000,000 EU/ml
• Removes more than 99.99%* of LPS
• Excellent sample recovery rate > 95%*
• Non-toxic phage-derived ligand, no cytotoxic effects
• Re-use more than 10 times
• Available in large quantities for up-scaling in biopharmaceutical processes
*Measured values for BSA, MAK 33 (monoclonal antibody) and POD (peroxidase) with EndoTrap HD®. 02.0
1.4
Endotoxin removal system
Removal rate> 99.99%
EndoTrap® HD removal efficiency:
Find out more on www.hyglos.de
For enquiries and further information contact:Hyglos GmbH tel +49 (0) 8158 9060 0Am Neuland 3 fax +49 (0) 8158 9060 21082347 Bernried, Germany [email protected]