Figure 1. Number of Tuberculosis Cases: California, 1930-2011 19 80 19 82 19 84 19 86 19 88 19 90 19 92 19 94 19 96 19 98 20 00 20 02 20 04 20 06 20 08 20 10 0 1,000 2,000 3,000 4,000 5,000 6,000 California Department of Public Health, Tuberculosis Control Branch N u m b e r o f T u b e r c u l o s i s C a s e s 1930 1940 1950 1960 1970 1980 2,000 4,000 6,000 8,000 10,000 12,000 Year
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Figure 1. Number of Tuberculosis Cases: California, 1930-2011 California Department of Public Health, Tuberculosis Control Branch Number of Tuberculosis.
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Figure 1. Number of Tuberculosis Cases: California, 1930-2011
1980
1982
1984
1986
1988
1990
1992
1994
1996
1998
2000
2002
2004
2006
2008
2010
0
1,000
2,000
3,000
4,000
5,000
6,000
California Department of Public Health, Tuberculosis Control Branch
Nu
mb
e r o
f Tu
ber
culo
s is
Cas
e s
1930 1940 1950 1960 1970 1980
2,000
4,000
6,000
8,000
10,000
12,000
Year
Figure 2. Number of Tuberculosis Cases and Case Rates: California, 2002-2011
* Match found in HIV/AIDS Registry, California Department of Public Health, Office of AIDS
California Department of Public Health, Tuberculosis Control Branch
1 2 3 4 5 6 7 8 9 100
5
10
15
20
25
30
35
40
45
50
Figure 12. Tuberculosis Cases with Multidrug Resistance (MDR) on Initial or Final Drug
Susceptibility Testing:* California, 2000-2009N
um
ber
of
MD
R
Tub
ercu
losi
s C
ases
*Cases with resistance to at least isoniazid, and either rifampin, rifabutin or rifapentine reported on the Initial Drug Susceptibility Report (Follow-up 1) or on the Case Completion Report (Follow-up 2)
35
43
34
41
36 37
2832 33
38
2001 20092000 2002 2003 2004 2005 2006 2007 2008
California Department of Public Health, Tuberculosis Control Branch
Initial Susceptibility Test Final Susceptibility Test
*Cases with initial drug resistance to at least isoniazid, and either rifampin, rifabutin or rifapentineCalifornia Department of Public Health, Tuberculosis Control Branch
Long Beach
Pasadena
Berkeley
San Francisco
³25 cases
15-24 cases
5-14 cases
1-4 cases
None
Initial MDR Cases:2007-2011
Figure 14. Tuberculosis Cases1 by Outcome of Therapy: California, 2009
Completed Therapy £12 Months1,780 (74.5%)
Completed Therapy >12 Months235 (9.8%)
Moved2
97 (4.1%)
Died180 (7.5%)
Lost3
21 (0.9%) Refused17 (0.7%)
Other31 (1.3%)
1 Patient was alive at diagnosis and started on an initial drug regimen of two or more drugs.2 Patient moved to another jurisdiction with a known forwarding address before treatment was completed;
final outcome not available.3 Patient could not be located prior to the completion of treatment.
NoInformation28 (1.2%)
California Department of Public Health, Tuberculosis Control Branch
Figure 15. Outcome in Tuberculosis Cases for Whom One Year or Less of Treatment was Indicated1:
California, 2009
Completed Therapy £12 Months1,770 (76.2%)
Completed Therapy >12 Months195 (8.4%)
Moved2
91 (3.9%)
Died175 (7.5%)
Lost3
21 (0.9%)
Refused16 (0.7%)
Other29 (1.2%)
NoInformation 25 (1.1%)
1 Excludes cases with rifampin resistant disease, cases with meningeal disease, and cases less than 15 years of age with disseminated tuberculosis disease.2 Patient moved to another jurisdiction with a known forwarding address before treatment was completed; final outcome not available.3 Patient could not be located prior to the completion of treatment.
California Department of Public Health, Tuberculosis Control Branch
Figure 16. Outcome in Tuberculosis Cases for Whom Greater than One Year of Treatment
was Indicated:1 California, 2009
Completed Therapy £12 Months10 (14.9%)
Completed Therapy >12 Months40 (60.0%)
Moved2
6 (9.0%)
Died5 (7.5%)
NoInformation 3 (4.5%)
1 Includes cases with rifampin resistant disease, cases with meningeal disease, and cases less than 15 years of age with disseminated tuberculosis disease.
2 Patient moved to another jurisdiction with a known forwarding address before treatment was completed; final outcome not available.
California Department of Public Health, Tuberculosis Control Branch
Refused1 (2.0%)
Other2 (3.0%)
Figure 17. Completion of Tuberculosis Therapy: California, 2000-2009
Note: Excludes cases with rifampin resistant disease, cases with meningeal disease, cases less than 15 years of age with disseminated tuberculosis disease, and those that died during treatment.
90
California Department of Public Health, Tuberculosis Control Branch