Tissues Classification Notes / Description / Size Picture / Illustration Tissue or Source 1 Picture / Illustration Tissue or Source 2 Picture / Illustration Tissue or Source 3 Picture / Illustration Tissue or Source 4 Picture / Illustration Tissue or Source 5 Picture / Illustration Tissue or Source 6 MAIN Sub Type Sub Type Sub Type Sub Type Sub Type Label source / reference Connective Fibrous Loose Areolar NA 1. Tendons attatched to bone is composed of thick, closely packed bundles of collagen fibrils oriented parallel to the long axis of the tendons. 2.The thick bands are the protein collagen while the thin dark threads are the protein elastic. 3. The fibers of areolar connective tissue are arranged in no particular pattern but run in all directions and form a loose network in the intercellular material. 4.It consist of fibroblast, collagen fiber, elastic fiber and macrophage 5. This image is labeled with fibroblast, collagen fiber, macrophage and elastic fiber Label FIBROUS LOOSE AREOLAR FIBROUS LOOSE source / reference g http://science.tjc.edu/images/histology/15_combined.jpg DC3C7D26.jpg http://www.cvm.tamu.edu/acvp/Cholelithiasis/5.JPG http://faculty.une.edu/com/abell/histo/LooseCT.jpg Adipose NA 1. Adipose taken from the umbilical cord. 2. The edge of the cell have nucleus which is dark purple, adipose cell is white and around the lined light purple is cytoplasmic membrane. 3. This image shows anterior adipocyte of the belly. 4. This is a histological section of mammary tissue from a nonpregnant woman: Label A = adipose tissue; C = connective tissue sheaths running through the adipose tissue; D - ducts growing. 5. This image shows the arrow pointing to macrophage (blue), nucleus (purple), annd the large pointer in adipocyteup through the connective tissue sheaths. UMBILICAL CORD 400X BELLY DERMIS MAMMARY TISSUE ge35U.JPG uloskeletal/adipose_tissue_white_40x.jpg T_adipose.jpg Reticular NA NA 1. A network of interlacing reticular fiber in dark purple and reticular cell in light purple. 2. This consists of reticular fibers and reticular cells interlaced to form a lose network that helps give structure to organs. The black reticular fibers located between reticular cells. 3. The cells that make the reticular fibers are fibroblasts called reticular cells. 4. The reticular fibers are attached to the reticular cells, so the two components of reticular connective tissue are "fixed", they cannot move around. The other cells and tissue fluid can move around in the spaces between the reticular fibers. 5. The red arrows point to individual reticular fibers. The dark-colored dots scattered among the fibers are mostly reticular cells and lymphocytes. STOMA SPLEEN LYMPH NODE LIVER LYMPH NODE es/115.jpg my/Histology/retic.jpg phNode_100x.jpg /reticular_connective_tissue.jpg g Dense Regular NA NA 1. The dark spots are nuclei of the fibroblasts that make the collagen fibers. 2. The bundles of collagen are all parallel to each other. The bar in this image shows you the width of this piece of dense regular connective tissue, which comes from a tendon. 3. Dense regular connective tissue is stained light that makes up the tendon and ligaments. The cell bodies are darkly stained and elongated. 4. The fibroblast nuclei (stained purple) are quite flat. Arrows indicate three fibroblast nuclei. Fibroblast nucleus (fb nuc) is labeled, but you can see other nuclei. The collagen fibers (cf) are parallel to the arrow bar. The "art" label indicates an artifact--a place where the collagen fibers pulled apart slightly during processing. TENDON LIGAMENTS TENDON/LIGAMENTS TENDON on.jpg http://faculty.une.edu/com/abell/histo/DenseRegCT2.jpg s.clayton.edu/Biology/BIOL1151L/lab03/new_images/densere pg Irregular NA NA 1.The connective tissue below the epithelium lining the surface of the skin. Beneath the skin forming the mammae, dense connective tissue areas are very extensive. This tissue surrounds the resting mammary gland. 2. The characterized of tissue by the presence of densely packed, interwoven bundles of pink-stained type I collagen fibers of various sizes. 3. This is typical dense irregular connective tissue, characterized by the interwoven network of various sized bundles of type I collagen fibers. The clear spaces are occupied by carbohydrate-rich ground substance that does not stain with iron hematoxylin. 4. This image shows the outer later of the heart. 5. The main component of dense irregular connective tissue. The fibroblasts that make the collagen fibers cannot be seen. NON LACTATING MAMMARY DERMIS SKIN PERICARDIUM SKIN http://www.ucc.ie/bluehist/CorePages/Connective/Images/nip0 21he.jpg http://casweb.ou.edu/pbell/Histology/Images/Slides/Connectiv e/63.dense.irreg.20.jpg http://casweb.ou.edu/pbell/Histology/Images/Slides/Connectiv e/pl.dense.irreg.ct.IH.100.jpg Elastic NA NA 1. This image of a cross section through an artery shows the sinuous bundles of elastic fibers that are present in the muscular walls of these blood vessels. 2. Elastic fibers are visible because they stain purple. 3. Consists of freely branching elastic fibers, fibroblasts are present in spaces betweek fibers. 4. This image of a cross section through a portion of the wall of a large artery shows the sinuous bundles of elastic fibers that are present in the muscular walls of these blood vessels. The elastic fibers are dark because of special staining. BLOOD VESSEL ARTERTY LUNG TISSUE LARGE ARTERY e/45.elast.c.t.40.JPEG tic2.jpg e/46.elastic.JPEG Supportive Cartilge Hyaline NA NA 1. Consist of bluish/white, shiny ground substance with fine collagen fibers and many chondrocytes. 2. Lacunae contain the chondrocytes, which are embedded in a smooth matrix. Chondroblasts, which secrete the matrix, can be seen at the top of the micrograph. 3. Hyaline cartilage contains cells called chondrocytes embedded in a unique matrix that gives the tissue both strength and flexibility. Thechondrocytes housed in their spaces called lacunae. 4. Developing of fetal ribs and several chondrocytes. 5. The different layer are layered from connective tissue, perichondrium, chondrocytes and matrix. LARYNX TRACHEA PERICHONDRIUM RIBS LONG BONE s.clayton.edu/Biology/BIOL1151L/lab03/new_images/hyaline 20Tissues/1-Hyaline%20Cartilage%20-%20Trachea.jpg http://microanatomy.net/bone/cartilage1.jpg http://microanatomy.net/bone/cartilage2.jpg http://www.med.mun.ca/anatomyts/msk/Bone18.gif Elastic NA NA 1. Consists of chondrocytes located in a threadlike network of elastic fibers within the extracellular matrix. 2. Elastic cartilage Lacunae containing the chondrocytes, which are characteristic of cartilage, are embedded in a matrix with elastic fibers. The fibers are dark pink. 3. The stain for elastin that brings out the dense bundles. 4. Elastic cartilage is flexible. It is found in the epiglottis, pinna of the ear, auditory tube and eustachian tube. It is organized in a similar way to hyaline cartilage with a perichondrium and chondroblasts and chondrocytes embedded in a matrix. The major difference is in the matrix where branched elastin fibres are present in addition to collagen AUDITORY TUBE EXTERNAL EAR EXTERNAL EAR EPIGLOTTIS http://a- s.clayton.edu/Biology/BIOL1151L/lab03/new_images/elastic_ http://www.technion.ac.il/~mdcourse/274203/slides/Skeletal% 20Tissues/2-Elastic%20Cartilage%20- Fibro NA NA 1. The lacunae are not as numerous in this cartilage and they are smaller. the nuclei of the chondrocytes is a red-purple color. 2. This image shows the fibrocartilage from an intervertebral disk. It is distinguished by very scattered, infrequent chondrocytes in dark cuclei collagen fibers running in the matrix. 3. In fibrocartilage the structure is intermediate between that of hyaline cartilage and dense connective tissue. It is found where bones are bound together such as at the pubic symphysis and as part of intervertebral discs. The cells are squeezed into rows by thick bundles of collagen fibres in the matrix. The collagen is orientated in the direction of stress. The gel component of the matrix is reduced compared to hyaline cartilage. 4. Here is tighter fibrocartilage from a pubic symphysis. INTERVERTEBRAL DISK INTERVERTEBRAL DISK PUBIC SYMPHYSIS PUBIC SYMPHYSIS s.clayton.edu/Biology/BIOL1151L/lab03/new_images/fibrous_ Bone Compact NA NA 1. There are two osteons in this micrograph. The dark and light ovals are the central canals or Haversian canals through which blood vessels and nerves project. Surrounding central canals are the lamellae with the osteocytes embedded in the solid calcium and phosphate matrix. The fine lines radiating out from the center are canaliculi. 2. This shows the architecture of compact bone which is designed to nourish and regulate osteocytes and bone matrix. 3. The osteon is labaled from inner to outer of haversion canal, lamella, canaliculi and lacuna. 4. The concentric layers of mineralized matrix called lamellae (Lm), surround the Haversian canal (Hc). Concentric arrays of almond-shaped lacunae (Lc) containing osteocytes are visible. Radiating from the Haversian canal in all directions are spaces or fine tubes called canaliculi (Cl). HUMERUS FEMUR TIBIA FIBULA s.clayton.edu/Biology/BIOL1151L/lab03/new_images/bone1.j http://www.cytochemistry.net/microanatomy/bone/bone1.jpg 202%20fireworks%20b.jpg ne-Osteon%20400X.jpg Spongy NA NA Sponge is made of bone or Trabeculae -{1} and the air is made of red bone marrow -{3}; the marrow produces red blood cells, cancellous cavities which contain Osteoblasts -{2}, The trabeculae are surrounded by a layer called the Periosteum marked as {4}. 2. An electron micrograph scan of spongy bone in an osteoporosis patient. Osteoporosis occurs when a body's blood calcium level is low and calcium from bones is dissolved into the blood to maintain a proper balance. 3. Cancellous bone showing its bony trabeculae (pink) and marrow tissue (blue). 4. It contains large marrow spaces defined by shelves and spicules of bone. The inner space is lined by osteoblasts and osteoclasts. LONG BONE OSTEOPEROSIS LONG BONE RIBS http://upload.wikimedia.org/wikipedia/commons/thumb/b/bc/S pongy_bone_-_trabecules.jpg/350px-Spongy_bone_- Fluid Blood Cells Erythrocytes NA 1. Human red blood cells in red from a leg wound. 2. Red Blood cell(RBC) also referred to as erythrocytes are the most common type of blood cell. This scanning electron micrograph that have been magnified a little over 11,000 times. Being biconcave in shape allow RBCs to have a greater surface area and carry more oxygen through your body. 3. Red blood cells (erythrocytes) trapped in a mesh of fibrin threads. Fibrin, a tough, insoluble protein formed after injury to the blood vessels, is an essential component of blood clots. 4. Ideal blood smear with neutrophil, lymphocyte and platelets. BLOOD BLOOD RBC with FIBRIN BLOOD SMEAR g ABEE/ZNVbA8UwO1k/s800/Looking-at-the-World-through-a- 5514AFAC.jpg .JPG Leukocytes Basophil 1. This type of WBC secrete heparin and histamine. Heparin keeps from clotting and histamine stimulates inflammation. 2. Bluish lack granules of univorm size within the cytoplasm and typically a bilobate nucleus. 3. Mast cell and basophil labeled. 4. Basophils constitue .5 to 3% of peripheral blood that release histamine and serotonin. BASOPHILS HUMAN BLOOD HUMAN BLOOd BLOOD SMEAR ll.JPG hil.jpg pg http://www.vghks.gov.tw/glab/images/Wbasophil.jpg Eosiniphil 1. Eosinophils, platelets and RBC is labeled on this image. 2. Eosinophils-- 10 to 15 um diameter and constitute 2.0 to 4.0% of leukocytes. 3. These cells usually contain a bilobate (two lobes) nucleus and a cytoplasm full of brightly stained eosinophilic (orange-red) specific granules. 4. Eosinophils function specifically as phagocytes to destroy larvae of parasites that have invaded tissues in trichinosis, schistosomiasis, and appear to play a role in allergic responses. Other functions of eosinophils include phagocytosis of antigen antibody complexes. HUMAN BLOOD HUMAN BLOOD HUMAN BLOOD HUMAN BLOOD http://eosinophilicesophagitis.files.wordpress.com/2009/03/eo sinophil4.jpg?w=196&h=139 http://www.spjc.edu/clw/math_science/Nicotera/pnic/Nicotera/ eosinophil1.jpg Neutrophil 1. The size of Neutrophil are 10 to 15 u diameter. 2. These cells constitute 70% of leukocytes and usually have 2 to 5 nuclear lobes connected by fine filaments of chromatin. Neutrophils are the most numerous of all leukocytes, 3. The cytoplasm is pink to grey because of the neutral staining of specific granules (i.e. they don't stain). 4. Neutrophils function as scavengers within extravascular tissue, destroying bacteria or other infectious organisms that invade the body. Neutrophils are also called Polymorphonuclear Leukocytes (PMNs) in some laboratories even though the following two cell types also have multi-lobed nuclei. HUMAN BLOOD HUMAN BLOOD HUMAN BLOOD HUMAN BLOOD neutrophil1.jpg 0X.jpg Lymphocyte 1. T lymphocytes in green are involved in the specific immune response and are composed mainly of precursor T cells and B cells. 2. Subsets of lymphocytes that originated in the red bone marrow from hematopoietic stem cells 3. Lymphocytes - 9 to 14 um diameter Lymphocytes constitute 20 - 25% of agranulocytes and may be small, medium or large in size. 4. The nucleus is rounded or oval, and usually the same size as an erythrocyte. The chromatin is densely packed with no apparent nucleoli. When compared with nuclei of other cells, the lymphocyte nucleus almost always appears smudged. 5. Stained blood smears you are using. Some lymphocytes migrate into the connective tissues and become Plasma Cells. LEG WOUND BONE MARROW HUMAN BLOOD HUMAN BLOOD LARGE GRANULE g g Monocyte 1. Monocytes - 12 to 20 um diameter, and comprise 3 - 8% of agranulocytes. 2. This large cell has a lightly stained nucleus that often appears horseshoe or kidney shaped. 3. The chromatin appears lacy and nucleoli are usually not apparent. 4. The abundant cytoplasm stain quite often contains vacuoles small, clear areas. HUMAN BLOOD HUMAN BLOOD HUMAN BLOOD HUMAN BLOOD http://www4.napavalley.edu/Projects/1799/13_Monocyte_400 X.jpg http://www.spjc.edu/clw/math_science/Nicotera/pnic/Nicotera/ monocyte1.jpg Macrophage 1. Tissue in purple/pink is a mature phagocyte that can ingest invading microbes, foreign particle and cellular debris. 2. Cell is seeking foreign bacteria(Escherichia coli) with specialized cell extensions called filopodia 3. This image is labeled with the ferritin particles in phagocytic vacuoles. 4. This low magnification image from the human umbilical cord shows the characteristic appearance of mucous connective tissue: sparsely scattered cells; sinuous collagen fibers; and lots of ground substance, which is unstained. About half of the nuclei seen belong to fibroblasts and the other half to macrophages, although it is usually not possible to tell them apart. LEG WOUND LUNG ALVEOLAR HUMAN BLOOD UMBILICAL CORD g g macro.jpg e/4.mucous.ct.20.JPEG Platelets 1. This image are comparason of the size of RBC, plateles and WBC. 2. They are irregular shaped, colourless bodies that are within our blood. The surface is sticky and with other substances, form clots to stop bleeding. The platelets gather at the wound and attempt to block the flow of blood.3. Human Red Blood Cells, Platelets and T-lymphocyte(erythocytes = red; platelets = yellow; T-lymphocyte = light green) 4. The average lifespan of a platelet is between 8 and 12 days. Platelets play a fundamental role in hemostasis and are a natural source of growth factors HUMAN BLOOD HUMAN BLOOD YELLOW HUMAN BLOOD http://2.bp.blogspot.com/_C- kqNjYlVIo/SfN75UDbBsI/AAAAAAAAABU/j4fd9XE_RSM/s320/ Plasma 1. Blood is a connective tissue consisting of cells suspended in an intercellular fluid (the blood plasma). 2.Blood functions to transport oxygen, carbon dioxide, nutrients, wastes, hormones, etc. to and from the body's cells. Blood cells consist of erythrocytes (red blood cells), leukocytes (white blood cells) and thrombocytes (platelets). 3.The above picture is a smear of human peripheral blood. 4. Final histological examination showed diffuse infiltration of mature and immature plasma cells in thyroid BLOOD SMEAR HUMAN BLOOD TONSIL THYROID 14.gif mainz.de/FB/Medizin/Anatomie/workshop/EM/eigeneEM/Tph 14.gif Lymph Lymph 1. Lymph nodules are unencapsulated lymphoid tissue located in several organs of the digestive and respiratory tracts, and all organs of the lymphatic system. They are composer of densely packed lymphocytes (mainly B- lymphocytes) that differentiate into plasma cells after appropriate antigenic stimulation. Secondary lymph nodules exhibit a pale staining germinal center, indicating that an antibody response to an antigen is occurring. Primary lymph nodules have not been activated, therefore, lack germinal centers. Peyer's patches are aggregates of unencapsulated nodules found in the lamina propria of the ileum. 2. Lymph nodes are spherical or kidney- shaped organs that are distributed throughout the body. The node is enclosed by a connective tissue capsule from which large connective tissue trabeculae arise and subdivide the underlying parenchyma. Each lymph ESOPHAGUS KIDNEY SPLEEN THYMUS py.jpg g g
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FIBROUS LOOSE AREOLAR FIBROUS LOOSE...Beneath the skin forming the mammae, dense connective tissue areas are very extensive. This tissue surrounds the resting mammary gland. 2. The
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Tissues Classification Notes / Description / Size Picture / Illustration Tissue or Source 1 Picture / Illustration Tissue or Source 2 Picture / Illustration Tissue or Source 3 Picture / Illustration Tissue or Source 4 Picture / Illustration Tissue or Source 5 Picture / Illustration Tissue or Source 6
MAIN Sub Type Sub Type Sub Type Sub Type Sub TypeLabel
source / reference
Connective Fibrous Loose Areolar NA
1. Tendons attatched to bone is composed of thick, closely packed bundles
of collagen fibrils oriented parallel to the long axis of the tendons. 2.The thick
bands are the protein collagen while the thin dark threads are the protein
elastic. 3. The fibers of areolar connective tissue are arranged in no
particular pattern but run in all directions and form a loose network in the
intercellular material. 4.It consist of fibroblast, collagen fiber, elastic fiber and
macrophage 5. This image is labeled with fibroblast, collagen fiber,