3 rd INTERNATIONAL FLUID ACADEMY DAYS – ORAL ABSTRACT SESSION Serum urea/creatinine ratio predicts successful loop diuretic therapy in congestive heart failure F.H. Verbrugge, J. Duchenne, M. Dupont, W. Mullens Department of Cardiology, Ziekenhuis Oost-Limburg, Belgium Faculty of Medicine & Life Sciences, Hasselt University, Belgium
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F.H. Verbrugge , J. Duchenne , M. Dupont, W. Mullens
3 rd INTERNATIONAL FLUID ACADEMY DAYS – ORAL ABSTRACT SESSION Serum urea/creatinine ratio predicts successful loop diuretic therapy in congestive heart failure. F.H. Verbrugge , J. Duchenne , M. Dupont, W. Mullens Department of Cardiology , Ziekenhuis Oost-Limburg, Belgium - PowerPoint PPT Presentation
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3rd INTERNATIONAL FLUID ACADEMY DAYS – ORAL ABSTRACT SESSION
Serum urea/creatinine ratio predicts successful loop diuretic therapy in congestive heart failure
F.H. Verbrugge, J. Duchenne, M. Dupont, W. Mullens
Department of Cardiology, Ziekenhuis Oost-Limburg, Belgium
Faculty of Medicine & Life Sciences, Hasselt University, Belgium
Background
2Hasselblad V et al. Eur J Heart Fail. 2007.
Background
3Verbrugge FH et al. Eur J Heart Fail. In press.
UREAREABSORPTION
Background
4Testani JM et al. J Am Coll Cardiol. 2011.
Objectives
1. To assess the prognostic value of the urea/creatinine
ratio (UCR) in patients admitted with heart failure (HF)
2. To assess the impact of the UCR on efficacy of loop
diuretic uptitration in HF
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Methods
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Cohort study in single tertiary care center
(Ziekenhuis Oost-Limburg, Genk, Belgium)
Consecutive patients admitted with a primary diagnosis of HF
(January, 2009 – March, 2011)
Loop diuretic uptitration: increase of maintenance dose at
discharge compared to admission
End-point: freedom from all-cause mortality or HF readmission