Extramural Funding Activities at NIH related to SSIB Christopher J. Lynch, Ph.D. Executive Secretary, NIH Nutrition Research Task Force Director, Office of Nutrition Research Chief, Nutrition Research Branch, DDN NIDDK, NIH
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Extramural Funding Activities at NIH related to SSIB
ChristopherJ.Lynch,Ph.D.ExecutiveSecretary,NIHNutritionResearchTaskForce
Director,OfficeofNutritionResearchChief,NutritionResearchBranch,DDN
NIDDK,NIH
Outline
• IntroducingOfficeofNutritionResearch• CurrentFOAsandInitiativesrelatedtoSSIB
– Rgrants– UgrantsandSBIR– SPARC
• ForwardLookingOpportunities– NutritionResearchStrategicPlan
NIHInitiativesRelatedtoIngestiveBehavior,
ResearchProjects
• UnderstandingFactorsinInfancyandEarlyChildhood(Birthto24months)ThatInfluenceObesityDevelopment (R01:PA-16-169)Methodologicalresearchgapsand/orcharacterizeinfantandearlychildhoodphenotypesthatmayincreaseormitigateriskforobesity.
• HealthyHabits:TimingforDevelopingSustainableHealthyBehaviorsinChildrenandAdolescents(R01:PA-14-177,R21:PA-14-176)Innovativeresearchtoidentifymechanismsofinfluenceand/orpromotepositivesustainablehealthbehavior(s)inchildrenandyouth(birthtoage2).
• AncillaryStudiestoIdentifyBehavioraland/orPsychologicalPhenotypesContributingtoObesity (R01:PAR-16-304) Supportstheadditionofmeasuresofpsychologicaland/orbehavioralconstructsorweight-relatedvariablestoexistingornewresearchstudiesinhumans
NIHInitiativesRelatedtoIngestiveBehavior-ResearchProjects
• ResearchontheMechanismsand/orBehavioralOutcomesofMultisensoryProcessing (R01:PA-15-347).Elucidatethemechanismsand/orbehavioraloutcomesofmultisensoryprocessing,theintegrationorprocessingofatleasttwodistincttypesofsensoryinputasdefinedbydistinctreceptor-typetransduction,neuralpathwaysandcognateperceptualquality.
• SystemsScienceandHealthintheBehavioralandSocialSciences (R01:PAR-15-048,R21:PAR-15-047).Appliedand/orbasic(includingmethodologicalandmeasurementdevelopment),haveahumanbehavioraland/orsocialsciencefocus,andemploymethodologiessuitedtoaddressingthecomplexityinherentinbehavioralandsocialphenomena,referredtoassystemssciencemethodologies.
NIHInitiativesRelatedtoIngestiveBehavior-ResearchProjects
• MethodologyandMeasurementintheBehavioralandSocialSciences (R01:PAR-16-260,R21:PAR-16-261).Aimedatimprovinganddevelopingmethodologyinthebehavioralandsocialsciencesthroughinnovationsinresearchdesign,measurement,datacollectionanddataanalysistechniques.
• MetabolicContributionstotheNeurocognitiveComplicationsofDiabetes:AncillaryStudies (R01:PAR-16-333).Humanstudiestoelucidatetheetiologyandpathogenesisoftheincreasedriskforneurocognitiveimpairmentassociatedwithtype2diabetes.
NIHInitiativesRelatedtoIngestiveBehavior-ResearchProjects
NIHInitiativesRelatedtoIngestiveBehavior,
SBIRandCooperativeAgreements
SBIRandCooperativeAgreements• LabtoMarketplace:ToolsforBiomedicalandBehavioralResearch (R43/R44:PA-15-052)Encouragesthetranslationoftechnologiesforbiomedicalorbehavioralresearchfromacademicandothernon-smallbusinessresearchsectorstothemarketplace
• LabtoMarketplace:ToolsforBrainandBehavioralResearch (R43/R44:PA-14-250).Encouragesthetranslationoftechnologiesforbrainorbehavioralresearchfromacademicandothernon-smallbusinessresearchsectorstothemarketplace.
SBIRandCooperativeAgreements• IntensiveLongitudinalAnalysisofHealthBehaviors:
LeveragingNewTechnologiestoUnderstandHealthBehaviors(U01:RFA-OD-17-004).Researchprojectsthatseektoexplainunderlyingmechanismsandpredicthealthbehaviorswithinindividualsovertimeutilizingintensivelongitudinal,within-personprotocolsthatleveragerecentadvancesinmobileandwirelesssensortechnologiesandbigdataanalytics.
• PredictiveMultiscaleModelsforBiomedical,Biological,Behavioral,EnvironmentalandClinicalResearch (U01:PAR-15-085).Interagencyfundingopportunitytosupportthedevelopmentofmultiscalemodelstoacceleratebiological,biomedical,behavioral,environmentalandclinicalresearch
SPARC - Stimulating Peripheral Activity to Relieve Conditions
~$238 million investment over 7 years
Opportunity: Neuromodulationoforganfunctionholdspromiseintreatingmanydiseases.
Challenge: Themechanismsofactionforneuromodulationtherapiesremainpoorlyunderstood.
ProgramGoals: Provideascientificfoundationthatenablesbetterunderstandingoftheneuralcontroloforganfunction,spurringdevelopmentofthenext-generationoftherapeuticclosed-loopneuromodulationdevices.
• RFA-RM-17-009 (OT1,a.k.a.”pre-application”)
• RFA-RM-17-010 (OT2,a.k.a.“application”)
• QuarterlyOT1receiptdates– nextdateisAugust1,2017
• ApplicantswhoseOT1pre-applicationsarefoundtobemeritoriousandprogrammaticallyrelevantwillbeinvited tosubmitafullOT2application
• OT2applicationsareinvitation-only
SPARC2 – Funding Opportunitieshttps://commonfund.nih.gov/sparc/grants
TechnologiestoUnderstandtheControlofOrganFunctionbythePeripheralNervousSystem
Application Processhttps://commonfund.nih.gov/sparc/OtherTransac
Discuss
• Optional,butencourageddiscussionwithSPARCprogramstaff
OT1application
• Emailsix-pageOT1applicationbyreceiptdateinRFA-RM-17-009
• MustproposetoaddressaPrioritylistedforthisreceiptdate
Feedback
• WewillprovidefeedbackonyourOT1application
• SomeapplicationswillbeinvitedtosubmitanOT2application
Discuss
•RequireddiscussionoffeedbackwithSPARCprogramstaff
OT2app
•Invitationspecifiesdeadlineandotherrequirements
•FollowRFA-RM-17-010tosubmitOT2applicationtoGrants.gov
Negotiate
•SPARCwillnegotiatebudget,benchmarks,anddeliverableswithselectedapplicants
Award
•NIHwillawardanOtherTransactionAward(OT2)aftersuccessfulnegotiation
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