Essential Oils for Healing Lyme Disease - …goodbyelyme.com/.../Essential_oils_for_healing_lyme_with_Greg_Lee… · 301.228.3764 [email protected] Objectives •Background

12/11/2015

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Greg Lee, M. Ac

Essential Oils for Healing

Lyme Disease

Stopping Persistent Lyme Disease

Free Training Webinar

Friday December 11th 3-4PM EST, 12-1PM PST

Two Frogs Healing Center10 N. Jefferson Street, Suite 203, Frederick, MD 21701www.GoodbyeLyme.com

301.228.3764 [email protected]

Objectives

• Background

• The question

• Challenges facing Lyme patients

• Overview of Essential Oils for Healing

Lyme Disease

Disclosure statement

• No grants

• No industry funding from drug, herb,

medical device suppliers

• Not a paid consultant

• Not on any committees, board of directors,

advisory panels, review boards

• Just me and my two frogs

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Who is Greg Lee?

• Grew up in Maryland

• 2nd Generation immigrant

family from China / Korea

• Loved watching NASA

astronauts land on the moon

• Member of the chess

club in High School

Career

• Technologist: Software engineer in NASA Robotics Lab, Hubble Space Telescope, spacecraft integration and testing, climate modeling projects

• Leadership: Managing partner at LionHeart Consulting

• Medical: Masters Degree of Acupuncture and Chinese herbal certification

• Master Sufi Healer

Two Frogs Healing Center

• Co-founder of the Two Frogs Healing Center, a Lyme Disease Clinic in Frederick, MD

• Treated several hundred people with Lyme and co-infections over the past 17 years

• Licensed acupuncturist and herbalist

• Do not use “protocols” over and over

• Customized treatment and remedies for each individual person

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Two Frogs Healing Center (cont’d)

• Natural treatments

– 23andMe genetics analysis

– Electrodermal scan for over 400 infections

– Acupuncture

– Cupping and bloodletting

– Cold laser

– Moxabustion

– Frequency Specific Microcurrent

– Cold laser

– Low light therapy

– Divine energy healing

Two Frogs Healing Center (cont’d)

• Natural remedies

– Liposomal / non-liposomal remedies• Herbs (organic, wildcrafted, lab tested)

• Essential oils (organic, wildcrafted)

• Supplements (effective in highly reactive, highly sensitive clients, children with autism)

– Bee venom

– German biological homeopathic remedies

• Provide training to medical providers on the “GoodbyeLyme System” for treating persistent Lyme disease

The Question

• How can essential oils help with healing

Lyme disease?

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Patient Challenges

• Around 10% accurately diagnosed (CDC)

• Patients are highly toxic from antibiotics,

environment, vaccines, metals, toxins,

lifestyle, dental procedures

• Multiple infections

(TBDs, parasites,

secondary infx,

fungi, viral)

untreated, under

treated

Patient Challenges (cont’d)

• Been misdiagnosed as depressed,

hypochondriac, hormonal, stressed

• Patients have genetic problems with

getting rid of toxins (methylation, HLA)

• Infections hide in reservoirs:

biofilms, cartilage, collagen, skin,

nervous system, inside cells

– Symptoms re-emerge, relapse

• Healing neurological problems,

cognitive difficulties, memory issues

Patient Challenges (cont’d)

• Immune system over producing

inflammation

• On multiple meds, supplements,

treatment regimens which can

change weekly

• Gut dysbiosis from antibiotic treatment

• Px resistance to taking bitter tasting herbs,

unusual supplements, needle treatment

• Highly reactive to herbs, supplements,

chemicals

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Tick Borne Infections

• Over 60 different infections can be

transmitted by tick bites

– Parasitic

• Single cell protozoa

– Bacteria

• Spirochetes

• Gram negative bacteria

– Viruses

– Fungi

Educating Patients

• Free e-newsletter and free e-report

• GoodbyeLyme.com website articles, blog, video

• Online training classes

• 3 hour class for all patients, i.e. am I a good fit?– Compassionately acknowledge attendees struggles

– Challenges and treatments for Lyme / MCIDs

– Treatment approaches

– Dietary recommendations

– Herb sampling

– Clinical results

– Address attendee concerns

• Brief one-on-one consult

Diagnosis/Treatment Paradigms

• Chinese medicine Gu Syndrome – 1900 year old system for treating relapsing

chronic infections

• Chinese Medicine Six levels of Illness

• HLA and methylation detoxification issues

• Western medical research on infections

• Heroes Journey / Monomyth by J. Campbell

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• Most doctors are confused by Gu pathologies

• Gu pathogens are malicious and life-threatening

• There are thousands of Gu toxins, all of which

cause different symptoms

• Gu toxins are like oil seeping into flour, you

cannot separate them out

• Gu pathogens operate in the dark

• Thriving parasites creating progressive organ

decay along with torturous pain and insanity

• Also translated as “demon syndrome”

• Treatment can take 3-5 years or longer (Fruehauf)

Paradigm: Gu Syndrome Properties

Gu Treatment Strategy

• Reduce toxicity and inflammation

• Replenish qi, blood, yin, yang, jing

• Move pain and neurological symptoms out

• Calm the emotions and spirit

• Kill the pathogenic infection(s)

• Dissolve biofilms

• Target pathogens in reservoirs/hiding areas

• Repair / restore healthy functioning

• Clear bad spirits and invoke Divine healing

Essential Oils (EOs)

• Essential oils (EOs) are highly

concentrated extracts of organic and

pesticide-free fruits, plants, and spices

• EOs have been used safely for decades in

food for flavoring, as antifungal and

antimicrobial agents for food preservation

• Most EOs classified as “generally

recognized as safe” (GRAS) by FDA

• EOs also have phenols which are solvents

which dissolve biofilms

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Essential Oils (cont’d)

• EOs have terpenes which are anti-

microbial

• EOs highly volatile penetration

• Enables kill germs in reservoirs: collagen,

cartilage, nervous system, and blood cells

• Many EOs are safe and non-toxic at low

doses, FDA GRAS

• Apply topically, sublingual, internally,

liposomally, rectally, vaginally, laser

remedy

Essential Oils (cont’d)

• Oral, sublingual, capsule, and liposomal

EOs maximizes absorption 5-10x over

topical application

Reduce LPS Toxicity EOs

• EOs and their active compounds protect

against endotoxins (LPS) in liver, blood,

tissues in lab and animal studies

– Linalool (lavender, thyme) (mouse study)

– Sandalwood (mouse)

– Common sage (Salvia officinalis L.) (lab)

– Cedar leaf (Thuja orientalis) (lab)

– Lavender (lab)

– Clove bud and it’s compound eugenol (lab,

mouse)

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Reduce LPS Toxicity EOs (cont’d)

– Angelicae pubescentis Radix (lab)

– Parsley (lab)

– Cinnamon leaf (mouse)

– Isoegomaketone (IK) component of Perilla

(lab)

– Octoea (lab)

– Carvacrol found in Thyme (lab)

– Spearmint (rat)

– Eucalyptus globulus (rat)

– Thyme (lab)

Reduce LPS Toxicity EOs (cont’d)

– Nutmeg (mouse)

– Terpinen-4-Ol from tea tree (Melaleuca

Alternifolia)

Reduce LPS Toxicity EOs Refs

• Li, Jingyuan, Xiaoyu Zhang, and Haiying Huang. “Protective Effect of Linalool against

lipopolysaccharide/D-Galactosamine-Induced Liver Injury in Mice.” International

Immunopharmacology 23, no. 2 (December 2014): 523–29. doi:10.1016/j.intimp.2014.10.001.

http://www.ncbi.nlm.nih.gov/pubmed/25311666

• Sharma, M., C. Levenson, R. H. Bell, S. A. Anderson, J. B. Hudson, C. C. Collins, and M. E. Cox.

“Suppression of Lipopolysaccharide-Stimulated Cytokine/chemokine Production in Skin Cells by

Sandalwood Oils and Purified α-Santalol and β-Santalol.” Phytotherapy Research: PTR 28, no. 6

(June 2014): 925–32. doi:10.1002/ptr.5080. http://www.ncbi.nlm.nih.gov/pubmed/24318647

• Abu-Darwish, M. S., C. Cabral, I. V. Ferreira, M. J. Gonçalves, C. Cavaleiro, M. T. Cruz, T. H. Al-

bdour, and L. Salgueiro. “Essential Oil of Common Sage (Salvia Officinalis L.) from Jordan:

Assessment of Safety in Mammalian Cells and Its Antifungal and Anti-Inflammatory Potential.”

BioMed Research International 2013 (2013): 538940. doi:10.1155/2013/538940.


• Kim, Ki Hyun, Eunjung Moon, Sun Yeou Kim, Sang Un Choi, Mi Won Son, Sang Zin Choi, and

Kang Ro Lee. “Bioactive Sesquiterpenes from the Essential Oil of Thuja Orientalis.” Planta Medica

79, no. 17 (November 2013): 1680–84. doi:10.1055/s-0033-1350952.


• Huang, Mei-Yu, May-Hua Liao, Yang-Kao Wang, Yung-Sheng Huang, and Hsiao-Chuan Wen.

“Effect of Lavender Essential Oil on LPS-Stimulated Inflammation.” The American Journal of

Chinese Medicine 40, no. 4 (2012): 845–59. doi:10.1142/S0192415X12500632.







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Reduce LPS Toxicity EOs Refs (cont’d)

• Bachiega, Tatiana Fernanda, João Paulo Barreto de Sousa, Jairo Kenupp Bastos, and José

Maurício Sforcin. “Clove and Eugenol in Noncytotoxic Concentrations Exert

Immunomodulatory/anti-Inflammatory Action on Cytokine Production by Murine Macrophages.”

The Journal of Pharmacy and Pharmacology 64, no. 4 (April 2012): 610–16. doi:10.1111/j.2042-

7158.2011.01440.x. http://www.ncbi.nlm.nih.gov/pubmed/22420667

• Sun, Wenchang, Longhe Yang, Yan Qiu, Jie Ren, Rui Huang, and Jin Fu. “[Identify nature N-

acylethanolamide-hydrolyzing acid amide (NAAA) inhibitor: effect of angelicae pubescentis radix

on anti-inflammation].” Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal

of Chinese Materia Medica 36, no. 22 (November 2011): 3161–66.


• Yousofi, Alireza, Saeed Daneshmandi, Neda Soleimani, Kambiz Bagheri, and Mohammad

Hossein Karimi. “Immunomodulatory Effect of Parsley (Petroselinum Crispum) Essential Oil on

Immune Cells: Mitogen-Activated Splenocytes and Peritoneal Macrophages.”

Immunopharmacology and Immunotoxicology 34, no. 2 (April 2012): 303–8.

doi:10.3109/08923973.2011.603338. http://www.ncbi.nlm.nih.gov/pubmed/21854170

• Tung, Yu-Tang, Chi-Chang Huang, Shang-Tse Ho, Yueh-Hsiung Kuo, Chi-Chen Lin, Chien-Tsong

Lin, and Jyh-Horng Wu. “Bioactive Phytochemicals of Leaf Essential Oils of Cinnamomum

Osmophloeum Prevent lipopolysaccharide/D-Galactosamine (LPS/D-GalN)-Induced Acute

Hepatitis in Mice.” Journal of Agricultural and Food Chemistry 59, no. 15 (August 10, 2011): 8117–

23. doi:10.1021/jf2018935. http://www.ncbi.nlm.nih.gov/pubmed/21699244


• Jin, Chang Hyun, Hyo Jung Lee, Yong Dae Park, Dae Seong Choi, Dong Sub Kim, Si-Yong Kang,

Kwon-Il Seo, and Il Yun Jeong. “Isoegomaketone Inhibits Lipopolysaccharide-Induced Nitric Oxide

Production in RAW 264.7 Macrophages through the Heme Oxygenase-1 Induction and Inhibition

of the Interferon-Beta-STAT-1 Pathway.” Journal of Agricultural and Food Chemistry 58, no. 2

(January 27, 2010): 860–67. doi:10.1021/jf9033333.


• Ballabeni, Vigilio, Massimiliano Tognolini, Carmine Giorgio, Simona Bertoni, Renato Bruni, and

Elisabetta Barocelli. “Ocotea Quixos Lam. Essential Oil: In Vitro and in Vivo Investigation on Its

Anti-Inflammatory Properties.” Fitoterapia 81, no. 4 (June 2010): 289–95.

doi:10.1016/j.fitote.2009.10.002. http://www.ncbi.nlm.nih.gov/pubmed/19825398

• Hotta, Mariko, Rieko Nakata, Michiko Katsukawa, Kazuyuki Hori, Saori Takahashi, and Hiroyasu

Inoue. “Carvacrol, a Component of Thyme Oil, Activates PPARalpha and Gamma and

Suppresses COX-2 Expression.” Journal of Lipid Research 51, no. 1 (January 2010): 132–39.

doi:10.1194/jlr.M900255-JLR200. http://www.ncbi.nlm.nih.gov/pubmed/19578162

• Rodrigues, T. G., A. Fernandes, J. P. B. Sousa, J. K. Bastos, and J. M. Sforcin. “In Vitro and in

Vivo Effects of Clove on pro-Inflammatory Cytokines Production by Macrophages.” Natural

Product Research 23, no. 4 (2009): 319–26. doi:10.1080/14786410802242679.


• Zhao, Chun-zhen, Yan Wang, Fa-di Tang, Xiao-jing Zhao, Qiao-ping Xu, Jin-fang Xia, and You-fa

Zhu. “[Effect of Spearmint oil on inflammation, oxidative alteration and Nrf2 expression in lung

tissue of COPD rats].” Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University.

Medical Sciences 37, no. 4 (July 2008): 357–63. http://www.ncbi.nlm.nih.gov/pubmed/18705008


• Zhao, Wei, Yan Wang, Fa-Di Tang, Xiao-Qing Xu, Hong-Yi Yao, You-Fa Zhu, and Ru-Lian Bian.

“[The expression of TLR4 in rat acute lung injury induced by lipopolysaccharide and the influence

of Eucalyptus globulus oil].” Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China

Journal of Chinese Materia Medica 31, no. 4 (February 2006): 319–22.


• Vigo, E., A. Cepeda, O. Gualillo, and R. Perez-Fernandez. “In-Vitro Anti-Inflammatory Effect of

Eucalyptus Globulus and Thymus Vulgaris: Nitric Oxide Inhibition in J774A.1 Murine

Macrophages.” The Journal of Pharmacy and Pharmacology 56, no. 2 (February 2004): 257–63.

doi:10.1211/0022357022665. http://www.ncbi.nlm.nih.gov/pubmed/15005885

• Morita, Tatsuya, Keiko Jinno, Hirokazu Kawagishi, Yasushi Arimoto, Hiroyuki Suganuma,

Takahiro Inakuma, and Kimio Sugiyama. “Hepatoprotective Effect of Myristicin from Nutmeg

(Myristica Fragrans) on Lipopolysaccharide/d-Galactosamine-Induced Liver Injury.” Journal of

Agricultural and Food Chemistry 51, no. 6 (March 12, 2003): 1560–65. doi:10.1021/jf020946n.


• Hart, P. H., C. Brand, C. F. Carson, T. V. Riley, R. H. Prager, and J. J. Finlay-Jones. “Terpinen-4-

Ol, the Main Component of the Essential Oil of Melaleuca Alternifolia (tea Tree Oil), Suppresses

Inflammatory Mediator Production by Activated Human Monocytes.” Inflammation Research:

Official Journal of the European Histamine Research Society ... [et Al.] 49, no. 11 (November

2000): 619–26. http://www.ncbi.nlm.nih.gov/pubmed/11131302













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Reduce Other Toxicity EOs Refs

• Bergamot (clears fire toxins)

• Celery seed (clears fire toxins)

• Helichrysum (clears fire toxins)

Reduce Other Toxicity EOs Refs

• Aldrich, Esther, and Randall Bornemann. Fang Xiang Liao Fa: Essential Oil Analogues of TCM

Herbal Formulas. CreateSpace Independent Publishing Platform, 2013.

https://books.google.com/books/about/Fang_Xiang_Liao_Fa.html.

Replenish Qi, Blood, Y/Y, Jing EOs

• EOs have properties for replenishing qi,

blood, yin, yang, and jing

– Angelica sinensis (invigorate and nourish

blood, tonify qi)

– Ajowan (tonify qi, tonify yang)

– Balsam (tonify qi)

– Basil (tonify yin, tonify qi, tonify yang)

– Benzoin (tonify yang)

– Cardamom (invigorate blood, tonify qi)

– Carrot seed (nourish blood, nourish yin)

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Replenish Qi, Blood, Y/Y, Jing EOs (cont’d)

– Cinnamon bark (invigorate and nourish blood,

tonify qi, tonify yang)

– Clary sage (nourish yin, tonify qi)

– Clove (tonify yang)

– Cumin (invigorate blood, tonify qi)

– Dill (invigorate blood)

– Eucalyptus radiate (tonify qi)

– Fennel (nourish yin, tonify qi, tonify yang)

– Fir (tonify qi)

– Frankincense (nourish blood, tonify qi)


– Geranium (nourish yin, tonify qi)

– German chamomile (nourish yin, tonify qi)

– Ginger (invigorate blood, tonify qi, tonify yang)

– Helichrysum (nourish blood)

– Hyssop (invigorate blood, tonify qi, tonify

yang)

– Juniper (tonify yang!)

– Lemon (invigorate blood)

– Lemongrass (nourish blood, tonify yang)

– Niaouli (invigorates blood, tonify qi)


– Nutmeg (nourish blood, tonify yang)

– Patchouli (tonify qi)

– Peppermint (tonify qi)

– Pine (tonify qi, tonify yang)

– Roman chamomile (nourish blood, nourish yin)

– Rosemary (nourish blood, tonify qi, tonify

yang)

– Sandalwood (nourish yin)

– Spruce(tonify qi, tonify yang)

– Tangerine (nourish blood)

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– Tea tree (invigorates blood)

– Thyme linalool (tonify qi)

– Vetiver (invigorates and nourishes blood)

– Ylang ylang (nourish yin, tonify qi)

Replenish Qi, Blood, Y/Y, Jing EOs Refs

• Aldrich, Esther, and Randall Bornemann. Fang Xiang Liao Fa: Essential Oil Analogues

of TCM Herbal Formulas. CreateSpace Independent Publishing Platform, 2013.

https://books.google.com/books/about/Fang_Xiang_Liao_Fa.html.

Move Pain Symptoms Out

• There are multiple patterns in

Chinese medicine that underlie pain

• These oils are classified as moving

qi, blood, wind, damp, and cold

factors which can increase pain

– Angelica sinensis (moves blood)

– Balsam (moves blood)

– Basil (release exterior)

– Benzoin (expel damp /cold)

– Bergamot (release exterior)

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Move Pain Symptoms Out (cont’d)

– Cajeput (expels damp heat, drains

damp, moves qi and blood)

– Carrot seed (drains damp)

– Cedarwood (dry dampness)

– Celery seed (expels wind dampness)

– Cinnamon (expels wind dampness,

drains dampness, expels cold)

– Cinnamon leaf (releases exterior)

– Clary sage (subdues wind)

– Clove bud (expels cold)


– Cypress (moves qi and blood)

– Dill (drains damp)

– Eucalyptus globulus (drains damp,

moves qi and blood, releases the

exterior)

– Eucalyptus radiate (drains damp,

resolves phlegm)

– Fennel (drains damp)

– Fir (expels damp heat, resolves

phlegm)


– Frankincense (clears heat, dry

dampness, resolves phlegm, moves qi

and blood)

– German chamomile (clears heat, drains

damp)

– Ginger (releases exterior, expels cold)

– Grapefruit (drain damp, resolve

phlegm)

– Helichrysum (expels damp heat, moves

qi and blood)

– Hyssop (expels damp cold)

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– Juniper (drains damp, resolves phlegm)

– Lavender (clears heat, releases the

exterior)

– Lemon (clears damp, clears heat)

– Lemongrass (expels cold)

– Melissa (clears heat, releases the

exterior)

– Myrrh (clears heat, dry dampness,

move qi and blood)

– Myrtle (clears heat, drains damp)


– Niaouli (clears wind damp, releases the

exterior)

– Nutmeg (moves qi and blood, expels

cold)

– Orange (clears heat, release exterior)

– Patchouli (clears heat, release exterior)

– Peppermint (clears heat, release

exterior, moves qi)

– Petitgrain (drains damp)


– Roman chamomile (clears heat,

subdues wind)

– Rosemary (releases exterior, expels

cold)

– Sandalwood (clears heat, dries damp,

moves qi and blood)

– Spearmint (releases exterior)

– Tangerine (moves qi and blood)

– Tea tree (clears heat, dries damp,

releases the exterior)

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– Thyme linalool (clears heat)

– Vetiver (clears heat)

– Ylang ylang (clears heat)

Antimicrobial Essential Oils

• Anti Lyme EOs

– Clove*

– Cinnamon*

– Sweet orange*

– Cistus

– *Unpublished research.

– Hutschenreuther A, Birkemeyer C, Grötzinger K, Straubinger

RK, Rauwald HW. Growth inhibiting activity of volatile oil from

Cistus creticus L. against Borrelia burgdorferi s.s. in vitro.

Pharmazie. 2010 Apr;65(4):290-5.


Antimicrobial Essential Oils (cont’d)

• Anti leptospirosis EO

– Senecio scandens, Chinese name: qian

li guang

– Wang D1, Huang L, Chen S Senecio scandens Buch.-Ham.: a

review on its ethnopharmacology, phytochemistry,

pharmacology, and toxicity. J Ethnopharmacol. 2013 Aug

26;149(1):1-23. doi: 10.1016/j.jep.2013.05.048. Epub 2013

Jun 7. http://www.ncbi.nlm.nih.gov/pubmed/23747644

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• Anti Protozoa EOs

– Malaria

• Basil, spp.

• Lemongrass

• Artemisia annua (toxic)

• Savory

• Thyme

– Babesia (no references)


• Anti Protozoa EOs– Malaria references

• Akono Ntonga P1, Baldovini N2, Mouray E3, Mambu L4, Belong P5, Grellier P3.

Activity of Ocimum basilicum, Ocimum canum, and Cymbopogon citratus essential oils

against Plasmodium falciparum and mature-stage larvae of Anopheles funestus s.s.

Parasite. 2014;21:33. doi: 10.1051/parasite/2014033. Epub 2014 Jul 7.


• Bilia AR1, Santomauro F2, Sacco C2, Bergonzi MC1, Donato R2. Essential Oil of

Artemisia annua L.: An Extraordinary Component with Numerous Antimicrobial

Properties. Evid Based Complement Alternat Med. 2014;2014:159819. doi:

10.1155/2014/159819. Epub 2014 Apr 1.


• Dell'Agli M1, Sanna C, Rubiolo P, Basilico N, Colombo E, Scaltrito MM, Ndiath MO,

Maccarone L, Taramelli D, Bicchi C, Ballero M, Bosisio E. Anti-plasmodial and

insecticidal activities of the essential oils of aromatic plants growing in the

Mediterranean area. Malar J. 2012 Jul 2;11:219. doi: 10.1186/1475-2875-11-219.




– Toxoplasmosis

• Thyme, Morrocan

• Dahbi A1, Bellete B, Flori P, Hssaine A, Elhachimi Y, Raberin H, Chait A, Tran Manh

Sung R, Hafid J. The effect of essential oils from Thymus broussonetii Boiss on

transmission of Toxoplasma gondii cysts in mice. Parasitol Res. 2010 Jun;107(1):55-8.

doi: 10.1007/s00436-010-1832-z. Epub 2010 Mar 25.



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• Anti Protozoa EOs - General (no

references)

– Bergamot

– Cardamom

– Ginger

– Tea tree

– Turmeric



– Giardia

• Clove

• Thymbra capitata

• Oregano

• Thymus zygis

• Verbena (Lippia graveolens)

• Peppermint

• Basil

• Lavender


• Anti Protozoa EOs– Giardia references

• Machado M1, Dinis AM, Salgueiro L, Custódio JB, Cavaleiro C, Sousa MC. Anti-

Giardia activity of Syzygium aromaticum essential oil and eugenol: effects on growth,

viability, adherence and ultrastructure. Exp Parasitol. 2011 Apr;127(4):732-9. doi:

10.1016/j.exppara.2011.01.011. Epub 2011 Jan 25.


• Machado M1, Dinis AM, Salgueiro L, Cavaleiro C, Custódio JB, Sousa Mdo C. Anti-

Giardia activity of phenolic-rich essential oils: effects of Thymbra capitata, Origanum

virens, Thymus zygis subsp. sylvestris, and Lippia graveolens on trophozoites growth,

viability, adherence, and ultrastructure. Parasitol Res. 2010 Apr;106(5):1205-15. doi:

10.1007/s00436-010-1800-7. Epub 2010 Mar 9.


• Machado M1, Sousa Mdo C, Salgueiro L, Cavaleiro C. Effects of essential oils on the

growth of Giardia lamblia trophozoites. Nat Prod Commun. 2010 Jan;5(1):137-41.


• de Almeida I1, Alviano DS, Vieira DP, Alves PB, Blank AF, Lopes AH, Alviano CS,

Rosa Mdo S. Antigiardial activity of Ocimum basilicum essential oil. Parasitol Res.

2007 Jul;101(2):443-52. Epub 2007 Mar 7.


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• Anti Protozoa EOs– Giardia references (cont’d)

• Moon T1, Wilkinson JM, Cavanagh HM. Antiparasitic activity of two Lavandula

essential oils against Giardia duodenalis, Trichomonas vaginalis and Hexamita inflata.

Parasitol Res. 2006 Nov;99(6):722-8. Epub 2006 Jun 2.



• Anti Brucellosis EOs

– Oregano syriacus

– Thyme syriacus

– Cinnamon

– Al-Mariri A1, Safi M. The Antibacterial Activity of Selected Labiatae

(Lamiaceae) Essential Oils against Brucella melitensis. Iran J Med

Sci. 2013 Mar;38(1):44-50.


– Al-Mariri A1, Saour G, Hamou R. In vitro antibacterial effects of five

volatile oil extracts against intramacrophage Brucella abortus 544.

Iran J Med Sci. 2012 Jun;37(2):119-25.



• Anti Bartonella EOs

– No references

– Artemisia EO (toxic)

– Houttunyia

• Anti Rocky Mountain Spotted Fever

EOs

– No references

• Anti Ehrlichia EOs

– No references

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• Anti Candida EOs

– Ajowan

– Angelica archangelica root

– Apple mint

– Artemisia annua leaf (external)

– Basil

– Black cumin (black seed)

– Carrot seed

– Catnip

– Cinnamon

– Lemon

– Lemon balm

– Lemongrass

– Mexican marigold (Tagetes)

– Myrtle

– Peppermint

– Pine

– Rosemary

– Summer savory

– Tansy

– Tea tree

– Thyme


• Anti Candida Eos (cont’d)

– Citronella (external)

– Clary sage oil, lavender oil, and ylang

ylang oil

– Clove bud

– Coriander leaf

– Coriander seed

– Cumin

– Dill seed

– Eucalyptus

– Lemon balm

– Lemongrass


– Myrtle

– Peppermint

– Pine

– Rosemary

– Summer savory

– Tansy

– Tea tree

– Thyme



– Fennel

– Galanga

– Geranium

– Holy basil (tulsi)

– Lemon

– Lemon balm

– Lemongrass


– Myrtle

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– Oregano

– Peppermint

– Pine

– Rose geranium

– Rosemary

– Sage

– Summer savory

– Tansy

– Tea tree



– Liposomal tea tree EO + silver ions

– Thyme

– Thyme, red


• Anti Candida EOs references– Shokri H1, Sharifzadeh A, Ashrafi Tamai I. Anti-Candida zeylanoides activity of some Iranian plants used in traditional medicine. J

Mycol Med. 2012 Sep;22(3):211-6. doi: 10.1016/j.mycmed.2012.04.006. Epub 2012 Aug 9. http://www.ncbi.nlm.nih.gov/pubmed/23518076

– Fraternale D1, Flamini G, Ricci D. Essential Oil Composition and Antimicrobial Activity of Angelica archangelica L. (Apiaceae)

Roots. J Med Food. 2014 Sep;17(9):1043-7. doi: 10.1089/jmf.2013.0012. Epub 2014 May 2.


– Stringaro A1, Vavala E2, Colone M1, Pepi F3, Mignogna G4, Garzoli S3, Cecchetti S5, Ragno R3, Angiolella L2. Effects of Mentha

suaveolens Essential Oil Alone or in Combination with Other Drugs in Candida albicans. Evid Based Complement Alternat Med.

2014;2014:125904. doi: 10.1155/2014/125904. Epub 2014 Feb 27. http://www.ncbi.nlm.nih.gov/pubmed/24719638

– Bilia AR1, Santomauro F2, Sacco C2, Bergonzi MC1, Donato R2. Essential Oil of Artemisia annua L.: An Extraordinary

Component with Numerous Antimicrobial Properties. Evid Based Complement Alternat Med. 2014;2014:159819. doi: 10.1155/2014/159819. Epub 2014 Apr 1. http://www.ncbi.nlm.nih.gov/pubmed/24799936

– Shirazi MT1, Gholami H1, Kavoosi G1, Rowshan V2, Tafsiry A1. Chemical composition, antioxidant, antimicrobial and cytotoxic

activities of Tagetes minuta and Ocimum basilicum essential oils. Food Sci Nutr. 2014 Mar;2(2):146-55. doi: 10.1002/fsn3.85.


– Rokbeni N1, M'rabet Y, Dziri S, Chaabane H, Jemli M, Fernandez X, Boulila A. Variation of the chemical composition and

antimicrobial activity of the essential oils of natural populations of Tunisian Daucus carota L. (Apiaceae). Chem Biodivers. 2013

Dec;10(12):2278-90. doi: 10.1002/cbdv.201300137. http://www.ncbi.nlm.nih.gov/pubmed/24327447

– Zomorodian K1, Saharkhiz MJ2, Rahimi MJ1, Shariatifard S3, Pakshir K1, Khashei R4. Chemical composition and antimicrobial

activities of essential oil of nepeta cataria L. Against common causes of oral infections. J Dent (Tehran). 2013 May;10(4):329-37. Epub 2013 May 31. http://www.ncbi.nlm.nih.gov/pubmed/24396352

– Białoń M1, Krzyśko-Łupicka T, Koszałkowska M, Wieczorek PP. The influence of chemical composition of commercial lemon

essential oils on the growth of Candida strains. Mycopathologia. 2014 Feb;177(1-2):29-39. doi: 10.1007/s11046-013-9723-3. Epub

2014 Jan 12. http://www.ncbi.nlm.nih.gov/pubmed/24436010

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• Anti Candida EOs references– Budzyńska A, Sadowska B, Więckowska-Szakiel M, Różalska B. Enzymatic profile, adhesive and invasive properties of Candida

albicans under the influence of selected plant essential oils. Acta Biochim Pol. 2014;61(1):115-21. Epub 2014 Mar 19. http://www.ncbi.nlm.nih.gov/pubmed/24644554

– Tadtong S1, Suppawat S, Tintawee A, Saramas P, Jareonvong S, Hongratanaworakit T. Antimicrobial activity of blended essential

oil preparation. Nat Prod Commun. 2012 Oct;7(10):1401-4. http://www.ncbi.nlm.nih.gov/pubmed/23157022

– Freires Ide A1, Murata RM2, Furletti VF3, Sartoratto A3, Alencar SM4, Figueira GM3, de Oliveira Rodrigues JA5, Duarte MC3,

Rosalen PL1. Coriandrum sativum L. (Coriander) essential oil: antifungal activity and mode of action on Candida spp., and

molecular targets affected in human whole-genome expression. PLoS One. 2014 Jun 5;9(6):e99086. doi:

10.1371/journal.pone.0099086. eCollection 2014. http://www.ncbi.nlm.nih.gov/pubmed/24901768

– Soares BV1, Morais SM, dos Santos Fontenelle RO, Queiroz VA, Vila-Nova NS, Pereira CM, Brito ES, Neto MA, Brito EH,

Cavalcante CS, Castelo-Branco DS, Rocha MF. Antifungal activity, toxicity and chemical composition of the essential oil of Coriandrum sativum L. fruits. Molecules. 2012 Jul 11;17(7):8439-48. doi: 10.3390/molecules17078439.


– Naeini A1, Naderi NJ2, Shokri H3. Analysis and in vitro anti-Candida antifungal activity of Cuminum cyminum and Salvadora

persica herbs extracts against pathogenic Candida strains. J Mycol Med. 2014 Mar;24(1):13-8. doi:

10.1016/j.mycmed.2013.09.006. Epub 2013 Nov 8. http://www.ncbi.nlm.nih.gov/pubmed/24210587

– Chen Y1, Zeng H2, Tian J1, Ban X1, Ma B1, Wang Y3. Dill (Anethum graveolens L.) seed essential oil induces Candida albicans

apoptosis in a metacaspase-dependent manner. Fungal Biol. 2014 Apr;118(4):394-401. doi: 10.1016/j.funbio.2014.02.004.


– Chen Y1, Zeng H, Tian J, Ban X, Ma B, Wang Y. Antifungal mechanism of essential oil from Anethum graveolens seeds against Candida albicans. J Med Microbiol. 2013 Aug;62(Pt 8):1175-83. doi: 10.1099/jmm.0.055467-0. Epub 2013 May 8.


– Piras A1, Falconieri D, Porcedda S, Marongiu B, Gonçalves MJ, Cavaleiro C, Salgueiro L. Supercritical CO2 extraction of volatile

oils from Sardinian Foeniculum vulgare ssp. vulgare (Apiaceae): chemical composition and biological activity. Nat Prod Res. 2014

Nov;28(21):1819-25. doi: 10.1080/14786419.2014.948874. Epub 2014 Aug 12. http://www.ncbi.nlm.nih.gov/pubmed/25115687


• Anti Candida EOs references– Tadtong S, Watthanachaiyingcharoen R, Kamkaen N. Antimicrobial constituents and synergism effect of the essential oils from

Cymbopogon citratus and Alpinia galanga. Nat Prod Commun. 2014 Feb;9(2):277-80. http://www.ncbi.nlm.nih.gov/pubmed/24689310

– Boukhatem MN1, Ferhat MA2, Kameli A3, Saidi F4, Kebir HT4. Lemon grass (Cymbopogon citratus) essential oil as a potent anti-

inflammatory and antifungal drugs. Libyan J Med. 2014 Sep 19;9:25431. doi: 10.3402/ljm.v9.25431. eCollection 2014.


– Vale-Silva L1, Silva MJ, Oliveira D, Gonçalves MJ, Cavaleiro C, Salgueiro L, Pinto E. Correlation of the chemical composition of

essential oils from Origanum vulgare subsp. virens with their in vitro activity against pathogenic yeasts and filamentous fungi. J

Med Microbiol. 2012 Feb;61(Pt 2):252-60. doi: 10.1099/jmm.0.036988-0. Epub 2011 Oct 20.


– Khan A1, Ahmad A1, Khan LA1, Manzoor N2. Ocimum sanctum (L.) essential oil and its lead molecules induce apoptosis in Candida albicans. Res Microbiol. 2014 Jul-Aug;165(6):411-9. doi: 10.1016/j.resmic.2014.05.031. Epub 2014 May 21.


– Khan A1, Ahmad A2, Xess I3, Khan LA1, Manzoor N4. Ocimum sanctum essential oil inhibits virulence attributes in Candida

albicans. Phytomedicine. 2014 Mar 15;21(4):448-52. doi: 10.1016/j.phymed.2013.10.028. Epub 2013 Nov 17.


– Gauch LM1, Silveira-Gomes F1, Esteves RA2, Pedrosa SS2, Gurgel ES3, Arruda AC4, Marques-da-Silva SH5. Effects of

Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers. Rev Soc Bras Med

Trop. 2014 May-Jun;47(3):389-91. http://www.ncbi.nlm.nih.gov/pubmed/25075493

– Cannas S1, Molicotti P, Usai D, Maxia A, Zanetti S. Antifungal, anti-biofilm and adhesion activity of the essential oil of Myrtus communis L. against Candida species. Nat Prod Res. 2014 Dec;28(23):2173-7. doi: 10.1080/14786419.2014.925892. Epub 2014

Jun 24. http://www.ncbi.nlm.nih.gov/pubmed/24960256

– Thosar N1, Basak S2, Bahadure RN3, Rajurkar M2. Antimicrobial efficacy of five essential oils against oral pathogens: An in vitro

study. Eur J Dent. 2013 Sep;7(Suppl 1):S71-7. doi: 10.4103/1305-7456.119078. http://www.ncbi.nlm.nih.gov/pubmed/24966732


• Anti Candida EOs references (cont’d)– Saharkhiz MJ1, Motamedi M, Zomorodian K, Pakshir K, Miri R, Hemyari K. Chemical Composition, Antifungal and Antibiofilm

Activities of the Essential Oil of Mentha piperita L. ISRN Pharm. 2012;2012:718645. doi: 10.5402/2012/718645. Epub 2012 Dec 13. http://www.ncbi.nlm.nih.gov/pubmed/23304561

– Sabzghabaee AM1, Shirdare Z, Ebadian B, Aslani A, Ghannadi A. Clinical evaluation of the essential oil of Pelargonium

graveolens for the treatment of denture stomatitis. Dent Res J (Isfahan). 2011 Dec;8(Suppl 1):S105-8.


– Sookto T1, Srithavaj T, Thaweboon S, Thaweboon B, Shrestha B. In vitro effects of Salvia officinalis L. essential oil on Candida

albicans. Asian Pac J Trop Biomed. 2013 May;3(5):376-80. doi: 10.1016/S2221-1691(13)60080-5.


– Anghel I1, Grumezescu AM, Holban AM, Ficai A, Anghel AG, Chifiriuc MC. Biohybrid nanostructured iron oxide nanoparticles and

Satureja hortensis to prevent fungal biofilm development. Int J Mol Sci. 2013 Sep 4;14(9):18110-23. doi: 10.3390/ijms140918110. http://www.ncbi.nlm.nih.gov/pubmed/24009022

– Piras A1, Falconieri D, Bagdonaite E, Maxia A, Gonçalves MJ, Cavaleiro C, Salgueiro L, Porcedda S. Chemical composition and

antifungal activity of supercritical extract and essential oil of Tanacetum vulgare growing wild in Lithuania. Nat Prod Res. 2014

Nov;28(21):1906-9. doi: 10.1080/14786419.2014.939085. Epub 2014 Jul 23. http://www.ncbi.nlm.nih.gov/pubmed/25055158

– Rajkowska K1, Kunicka-Styczyńska A1, Maroszyńska M2, Dąbrowska M3. The effect of thyme and tea tree oils on morphology

and metabolism of Candida albicans. Acta Biochim Pol. 2014;61(2):305-10. Epub 2014 Jun 13.


– Tullio V1, Mandras N, Allizond V, Nostro A, Roana J, Merlino C, Banche G, Scalas D, Cuffini AM. Positive interaction of thyme

(red) essential oil with human polymorphonuclear granulocytes in eradicating intracellular Candida albicans. Planta Med. 2012Oct;78(15):1633-5. doi: 10.1055/s-0032-1315153. Epub 2012 Aug 7. http://www.ncbi.nlm.nih.gov/pubmed/22872591








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• Anti Aspergillus EOs

– Acorus, calamus, sweet flag (external)

– Ajowan

– Bay

– Caraway

– Cinnamon

– Clove

– Clove basil

– Cumin seed

– Fennel


• Anti Aspergillus EOs (cont’d)

– Lemongrass

– Oregano

– Palmarosa

– Rosemary

– Sage (external)

– Thyme

– Turmeric


• Anti Aspergillus EOs references– Satyal P1, Paudel P, Poudel A, Dosoky NS, Moriarity DM, Vogler B, Setzer WN. Chemical compositions, phytotoxicity, and

biological activities of Acorus calamus essential oils from Nepal. http://www.ncbi.nlm.nih.gov/pubmed/24079199Nat Prod Commun. 2013 Aug;8(8):1179-81. http://www.ncbi.nlm.nih.gov/pubmed/24079199

– Sessou P1, Farougou S1, Ahounou S1, Hounnankpon Y2, Azokpota P2, Youssao I1, Sohounhloue D3. Comparative study of

antifungal activities of six selected essential oils against fungal isolates from cheese wagashi in Benin. Pak J Biol Sci. 2013 Dec

1;16(23):1751-7. http://www.ncbi.nlm.nih.gov/pubmed/24506043

– Gniewosz M1, Kraśniewska K, Woreta M, Kosakowska O. Antimicrobial activity of a pullulan-caraway essential oil coating on

reduction of food microorganisms and quality in fresh baby carrot. J Food Sci. 2013 Aug;78(8):M1242-8. doi: 10.1111/1750-

3841.12217. http://www.ncbi.nlm.nih.gov/pubmed/23957414

– Khan MS1, Ahmad I2, Cameotra SS3. Carum copticum and Thymus vulgaris oils inhibit virulence in Trichophyton rubrum and

Aspergillus spp. Braz J Microbiol. 2014 Aug 29;45(2):523-31. eCollection 2014. http://www.ncbi.nlm.nih.gov/pubmed/25242937

– Kedia A1, Prakash B, Mishra PK, Dubey NK. Antifungal and antiaflatoxigenic properties of Cuminum cyminum (L.) seed essential oil and its efficacy as a preservative in stored commodities. Int J Food Microbiol. 2014 Jan 3;168-169:1-7. doi:

10.1016/j.ijfoodmicro.2013.10.008. Epub 2013 Oct 23. http://www.ncbi.nlm.nih.gov/pubmed/24211773

– Hua H, Xing F, Selvaraj JN, Wang Y, Zhao Y, Zhou L, Liu X, Liu Y. Inhibitory Effect of Essential Oils on Aspergillus ochraceus

Growth and Ochratoxin A Production. PLoS One. 2014 Sep 25;9(9):e108285. doi: 10.1371/journal.pone.0108285. eCollection

2014. http://www.ncbi.nlm.nih.gov/pubmed/25255251

– Gemeda N1, Woldeamanuel Y2, Asrat D2, Debella A1. Effect of essential oils on Aspergillus spore germination, growth and

mycotoxin production: a potential source of botanical food preservative. Asian Pac J Trop Biomed. 2014 May;4(Suppl 1):S373-81.

doi: 10.12980/APJTB.4.2014C857. http://www.ncbi.nlm.nih.gov/pubmed/25183114

– Boukhatem MN1, Ferhat MA2, Kameli A3, Saidi F4, Kebir HT4. Lemon grass (Cymbopogon citratus) essential oil as a potent anti-inflammatory and antifungal drugs. Libyan J Med. 2014 Sep 19;9:25431. doi: 10.3402/ljm.v9.25431. eCollection 2014.


– Esper RH1, Gonçalez E1, Marques MO2, Felicio RC3, Felicio JD1. Potential of essential oils for protection of grains contaminated

by aflatoxin produced by Aspergillus flavus. Front Microbiol. 2014 Jun 4;5:269. doi: 10.3389/fmicb.2014.00269. eCollection 2014.





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• Anti Aspergillus EOs references (cont’d)– de Sousa LL1, de Andrade SC, Athayde AJ, de Oliveira CE, de Sales CV, Madruga MS, de Souza EL. Efficacy of Origanum

vulgare L. and Rosmarinus officinalis L. essential oils in combination to control postharvest pathogenic Aspergilli and autochthonous mycoflora in Vitis labrusca L. (table grapes). Int J Food Microbiol. 2013 Aug 1;165(3):312-8. doi:

10.1016/j.ijfoodmicro.2013.06.001. Epub 2013 Jun 10. http://www.ncbi.nlm.nih.gov/pubmed/23810954

– Abu-Darwish MS1, Cabral C, Ferreira IV, Gonçalves MJ, Cavaleiro C, Cruz MT, Al-bdour TH, Salgueiro L. Essential oil of

common sage (Salvia officinalis L.) from Jordan: assessment of safety in mammalian cells and its antifungal and anti-

inflammatory potential. Biomed Res Int. 2013;2013:538940. doi: 10.1155/2013/538940. Epub 2013 Oct 9.


– Dias Ferreira F1, Mossini SA1, Dias Ferreira FM1, Arrotéia CC2, da Costa CL2, Nakamura CV1, Machinski M Jr1. The

inhibitory effects of Curcuma longa L. essential oil and curcumin on Aspergillus flavus link growth and morphology. ScientificWorldJournal. 2013 Dec 3;2013:343804. doi: 10.1155/2013/343804. eCollection 2013.



• Anti Clostridium Dificile (C. Diff) EOs

– Angelica archangelica root

– Cinnamon


• Anti Clostridium Dificile (C. Diff) EOs

references– Fraternale D1, Flamini G, Ricci D. Essential Oil Composition and Antimicrobial Activity of Angelica archangelica L. (Apiaceae)

Roots. J Med Food. 2014 Sep;17(9):1043-7. doi: 10.1089/jmf.2013.0012. Epub 2014 May 2.


– Shahverdi AR1, Monsef-Esfahani HR, Tavasoli F, Zaheri A, Mirjani R. Trans-cinnamaldehyde from Cinnamomum zeylanicum bark

essential oil reduces the clindamycin resistance of Clostridium difficile in vitro. J Food Sci. 2007 Jan;72(1):S055-8.



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Liposomal EOs for Hidden Infections

• Micronized (turbocharged) anti-microbial

oils wrapped in a lipid (lecithin)

• Germs eat lipids containing

antimicrobial EOs which kill them

• Target systemic infections and toxicity in

hard to reach reservoirs: cartilage, blood

cells, collagen, nervous system, parasites

• Liposomal EOs penetrate deeper into

reservoirs vs non-liposomal EOs

Cold Laser EO Treatment

• Shining a 650 nm laser through a glass vial containing essential oil extracts, homeopathic remedies to reduce local symptoms– Can also affect areas of the body that are

non-local

– Can relieve symptoms in deep areas of the brain, joints, and organs

– Works especially well with chronically infected patients that are universal reactors

Essential Oil Anti-Biofilm Strategy

• Essential oils that penetrate Lyme biofilms

– Cinnamon

– Clove

– Sweet Orange

– Cypress

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Essential Oil Anti-Biofilm Strategy

• Essential oils that penetrate other biofilms

– Bergamot EO

– Rose EO

– Geranium EO

– Lavender EO

– Lemongrass EO

– Peppermint EO

– Spearmint EO

– Thyme EO

How to Add EOs to Your Practice

• Low hanging fruit strategy– Choose the easiest one to implement first– Consult with a Lyme literate essential oil

practitioner

Conclusion

• Many challenges to healing people with Lyme disease and multiple infections

• Using essential oils to nourish, move, and go after pathogens can help Lyme patients relieve persistent symptoms due to toxins, inflammation, hypercoagulation, and multiple infections.

Greg Leewww.GoodbyeLyme.com/thinktank301-228-376410 N. Jefferson St., Frederick, MD [email protected]

http://www.goodbyelyme.com/thinktank

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6 Week Online Training

• Stopping Persistent Lyme Disease ONLINE Training Seminar from Friday January 8th –February 12th for medical providers– The unique “signature” symptoms which helps you to

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– A simple Chinese medicine system for making sense of and treating a confusing array of Lyme disease symptoms

– Which herbal remedies and oils help to detoxify and to stop persistent infections

– Which herbs, essential oils, and supplements help to heal Leaky Gut which is a common obstacle to healing in Lyme patients

6 Week Online Training

• Stopping Persistent Lyme Disease ONLINE Training Seminar from Friday January 8th –February 12th for medical providers– How to make liposomal remedies to evict germs

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• BONUS: Practitioners that sign up today get a Laser + Homeopathic Remedy Kit ($100 value)

• Limited # Spaces Left! More information:http://goodbyelyme.com/training

Essential Oils for Healing Lyme Disease - …goodbyelyme.com/.../Essential_oils_for_healing_lyme_with_Greg_Lee… · 301.228.3764 [email protected] Objectives •Background

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