ERYTHROPOEISIS Hemocytoblast Proerythroblast Erythroblast Basophilic Polychroma- tophilic Erythroblast Orthochroma- tophilic Erythroblast Nuclear Extrusion Reticulocyte RBC Pluripotential Stem Cell 1. dispersed chromatin 2. nucleoli 3. cytoplasmic 1. clumped chromatin 2. no nucleoli 3. maximum 1. condensed chromatin 2. grey-green cytoplasm (hemoglobin synthesis) 1. condensed eccentric nucleus 2. pink cytoplasm 1. anucleate 2. spherical 3. slight basophilia basophilia basophilia (free ribosomes)
ERYTHROPOEISIS HemocytoblastProerythroblast Erythroblast BasophilicPolychroma- tophilic Erythroblast Orthochroma- tophilic Erythroblast Nuclear Extrusion.
Dec 16, 2015
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ERYTHROPOEISIS
Hemocytoblast Proerythroblast Erythroblast Basophilic Polychroma-
tophilicErythroblast
Orthochroma-tophilic
ErythroblastNuclearExtrusion
Reticulocyte
RBC
PluripotentialStem Cell
1. dispersedchromatin
2. nucleoli
3. cytoplasmic
1. clumpedchromatin
2. no nucleoli
3. maximum
1. condensedchromatin
2. grey-greencytoplasm
(hemoglobinsynthesis)
1. condensedeccentricnucleus
2. pinkcytoplasm
1. anucleate
2. spherical
3. slight basophilia
basophilia basophilia (free ribosomes)
Erythropoeisis- Several Stages
MYELOPOEISIS (granulopoeisis)
Hemocytoblast (multipotential)
Myeloblast (multipotential)
Promyelocyte (multipotential)
1. loss of cytoplasmicbasophilia
2. dispersed chromatin
Eosinophilopoeisis Neutrophilopoeisis Basophilopoeisis
EOSINOPHILOPOEISIS Eosinophilic
MyelocyteEosinophilic
Metamyelocyte Eosinophil(band cell)
Specific andMetachromatic Granules
Eosinophilopoeisis- Several Stages
NEUTROPHILOPOEISIS NEUTROPHILIC
MYELOCYTENEUTROPHILIC
METAMYELOCYTE NEUTROPHIL
MYELOPOEISIS (Several Stages)
Neutrophilic and Eosinophilic Band CellsNutrophilic Band and
Eosinophilic Metamyelocyte
BASOPHILOPOEISIS Basophilic Myelocyte
Basophilic Metamyelocyte Basophil
THROMBOPOEISIS
Hemocytoblast
Endomytosis(w/o karyokinesis
(w/o cytokinesis)
Reserve Megakaryocyte (megakaryoblast) Platelet-Forming Megakaryocyte
Platelet-Shedding
(fusion ofplasma membrane)
PlateletsResidual Megakaryocyte
MEGAKARYOCYTES
BONE MARROW
Decalcified Bone and Marrow Cavity
Marrow
Fat Cells
Bone
Marrow
Megakaryocyte
AdipocyteDiapedesis
HemopoeticCompartment
EndothelialDiscontinuity
Endothelial Cells
BloodSinusoid
ReticularFibers
Bone Marrow
Bone Marrow in Decalcified Bone Bone Marrow Smear
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