1 EPITHELIUM TISSUE CHARACTERISTICS: *MOST named by number of layers and cell shape *AVASCULAR *Located as covering or lining of hollow organs, cavities, or vessels – know specific location of each type & function *ID lumen, basement membrane, nucleus, & specialized structures *Specialized structures: -cilia, stereocilia, microvilli, goblet cells, and keratin (know function and location) ORGANIZATION: I. Single layer a. Simple Squamous b. Simple Cuboidal c. Simple Columnar d. Pseudostratified Columnar II. 2 or more layers a. Stratified Squamous b. Stratified Cuboidal c. Stratified Columnar d. Transitional ADDITIONAL SLIDES: GI – Slide 9 (GE junction) GI – Slide 14 (Duodenum) GI – Slide 21 (Colon) MALE – Slide 15 (Epididymis) URINARY – Slide 16 (Ureter)
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EPITHELIUM TISSUECHARACTERISTICS:
*MOST named by number of layers and cell shape*AVASCULAR*Located as covering or lining of hollow organs, cavities, or vessels
– know specific location of each type & function*ID lumen, basement membrane, nucleus, & specialized structures*Specialized structures:
-cilia, stereocilia, microvilli, goblet cells, and keratin (know function and location)
ORGANIZATION:I. Single layer
a. Simple Squamousb. Simple Cuboidalc. Simple Columnard. Pseudostratified Columnar
II. 2 or more layersa. Stratified Squamousb. Stratified Cuboidalc. Stratified Columnard. Transitional
Simple Columnar – Nonciliated (1): Areolar CT(2):LCN: GI (stomach-anus), ducts, GB LCN: “packing material”FXN: Secretion, absorption FXN: Strength, elasticity, and support
1
2
Collagen Fibers
RBCs in capillaries:**d/t epithelium is AVASCULAR**
Ground Substance
Fibroblast:Flat cells w/ branching processes
MacrophageCells
5
6
EPITHELIUM – SLIDE 3B BRONCHIOLES
Ciliated Simple Columnar (1): Dense Irregular CT (2):Respiratory tract (bronchioles), uterine tubes Less ground substanceFXN: trap and move particles FXN: tensile strength in across surface; oocyte transport many directions
1
2
lumen
Basement membrane
EPITHELIUM - SLIDE 4 – TRACHEA
Pseudostratified Columnar (1): Dense Irregular CT (2):Ciliated w/ Goblet Cells: Less ground substanceUpper respiratory tract FXN: tensile strength in many directionsFXN: trap and move particles across surfaceNon-ciliated w/o goblet cells: Larger ducts, epididymis, male urethra
Basement membrane
lumen
1
Cilia
2
Collagen Fibers
7
EPITHELIUM - SLIDE 5A – LIP
Basement membrane
External area
Nuclei
Stratified Squamous – Nonkeratinized (aka: Moist):LCN: lining of mouth, esophagus, and vaginaFXN: protection and first line of defense from microbes
8
**Flat nucleus on apical surface**
9
EPITHELIUM - SLIDE 5B – SKIN
Stratified Squamous – Keratinized (1):LCN: Superficial layer of the skinFXN: First line of defense from microbes; *protection from heatwater loss, and UV light*.Be sure to refer to Chapter 5 to determine specific layers of the Integumentary system.
Basement membrane
*Keratin*
External area
1
2 DCT
10
EPITHELIUM - SLIDE 6 – SWEAT GLANDS
Stratified Cuboidal: **no more than 2 layers**LCN: ducts of sweat & esophageal glands, male urethraFXN: Limited secretion (thermal regulation) & absorption
Basement membrane
lumen
11
EPITHELIUM - SLIDE 7
Stratified Columnar: **no more than 2 layers**LCN: part of urethra, some large ducts, conjunctiva of eye FXN: Limited secretion and absorption
Basement membrane
lumen
12
EPITHELIUM - SLIDE 8 –
Transitional: **don’t confuse with stratified squamous**LCN: Urinary bladder, ureters, and urethraFXN: Stretch without rupturing (distention)
Basement membrane
lumen
**Rounded surface in relaxed state; with round nuclei**