12-Jul-17 1 Epidemiology of varicella zoster virus infections in Australia, 1998-2015 Meru Sheel, Helen Quinn, Frank Beard, Aditi Dey, Martyn Kirk, Kristine Macartney MAE Scholar National Centre for Immunisation Research and Surveillance National Centre for Epidemiology and population Health, Australian National University Varicella (chicken pox) • Primary infection with varicella zoster virus (VZV) • Acute and self-limiting • Severe complications • November 2005, vaccine funded under the National Immunisation Program (NIP) • Children aged 18 months
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12-Jul-17
1
Epidemiology of varicella
zoster virus infections in
Australia, 1998-2015
Meru Sheel, Helen Quinn, Frank Beard, Aditi Dey, Martyn Kirk,
Kristine Macartney
MAE Scholar
National Centre for Immunisation Research and Surveillance
National Centre for Epidemiology and population Health,
Australian National University
Varicella (chicken pox)
• Primary infection with varicella
zoster virus (VZV)
• Acute and self-limiting
• Severe complications
• November 2005, vaccine
funded under the National
Immunisation Program (NIP)
• Children aged 18 months
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Herpes zoster (shingles)
• Reactivation of latent VZV
• Rash accompanied with acute pain
• Severe complications: Post-herpetic neuralgia (PHN)
• November 2016, vaccine funded under the NIP
• Adults aged 70-79 years
Study Aims
• Epidemiological review of varicella and herpes
zoster
• Baseline for herpes zoster
• Assess the impact of the national varicella
immunisation program
• Varicella
• Herpes zoster (HZ)
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Data sources
National Notifiable Diseases Surveillance System (NNDSS)
2002-2015
National Mortality Database & Causes of Death Data, Australian
Coordinating Registry and Australian Bureau of Statistics
1998-2013
Mid-year population estimates from the Australian Bureau of Statistics
National Hospital Morbidity Database maintained by the Australian Institute of
Health and Welfare1999-2013
ICD-10-AMVaricella: B01.0- B01.9
HZ: B02.0- B02.9PHN: B022, G530, G531
Analyses
• Rates per 100,000
• Notifications
• Hospitalisations
• Principal diagnoses
• Negative binomial regression
• Pre-varicella vaccine (1999-2004) versus post-varicella