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July 2017 Volume 8, Issue 7 Points of Interest: Dengue Outbreak in Sri Lanka Zoonotic Transmission of Campylobacter Epidemiology Monthly Surveillance Report Contents Dengue Outbreak in Sri Lanka 1 Influenza Surveillance 3 Emerging Disease Surveillance - Zika 4 Gastrointestinal Illness Surveillance 5 Arboviral Surveillance 6 Outbreaks 7 Reportable Diseases Table 8 Zoonotic Transmission of Campylobacter 9 Resources 10 Florida Department of Health in Orange County Dengue Outbreak in Sri Lanka As mosquito season is under way in various parts of the world, the Florida Department of Health in Orange County (DOH-Orange) advises clinicians to consider testing travelers for arbovirus/febrile illnesses for travelers returning from endemic areas, especially Sri Lanka, as there is currently a large active dengue outbreak. In Florida, the majority of reported cases are travel associated which have been imported from dengue-endemic countries. Most people present with mild symptoms that include: fever, headache, retro-orbital pain, joint and muscle pain, and rash. Many other febrile illnesses (e.g. Zika, Chikungunya, malaria, etc.) present with the similar symptoms and it may be hard to differentiate among illnesses without laboratory evidence. Current Dengue Outbreak in Sri Lanka According to the World Health Organization (WHO), Sri Lanka has seen a 4-fold increase in dengue cases this year, compared to the same time period during 2010-2016. As of July 28, 2017, there have been 110,372 dengue cases and 301 deaths reported to the Ministry of Health, Nutrition and Indigenous Medicine (MoH) Sri Lanka for the 2017 year, with the most cases reported from June 30, 2017- July 7, 2017 in the Western province. Interestingly, DENV-2 is reportedly over 50% of current specimens which have been serotyped, but it has not been the main strain identified in individuals since 2009, which was the genotype of DENV-1. Immunity to dengue through previous infection is specific by serotype, so previous infection with DENV-1 does not provide immunity to DENV-2, DENV- 3, or DENV-4.
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Page 1: Epidemiology Monthly Surveillance Reportorange.floridahealth.gov/.../epidemiology/_documents/surveillance-7-17.pdfmultiple countries in the Caribbean, Central and South America, and

July 2017

Volume 8, Issue 7

Points of Interest:

Dengue Outbreak in Sri Lanka

Zoonotic Transmission of Campylobacter

Epidemiology Monthly Surveillance Report

Contents

Dengue Outbreak

in Sri Lanka

1

Influenza

Surveillance

3

Emerging Disease

Surveillance - Zika

4

Gastrointestinal

Illness

Surveillance

5

Arboviral

Surveillance 6

Outbreaks 7

Reportable

Diseases Table

8

Zoonotic

Transmission of

Campylobacter

9

Resources 10

Florida Department of Health in Orange County

Dengue Outbreak in Sri Lanka

As mosquito season is under way in various parts of the world, the Florida Department of Health in Orange County (DOH-Orange) advises clinicians to consider testing travelers for arbovirus/febrile illnesses for travelers returning from endemic areas, especially Sri Lanka, as there is currently a large active dengue outbreak. In Florida, the majority of reported cases are travel associated which have been imported from dengue-endemic countries. Most people present with mild symptoms that include: fever, headache, retro-orbital pain, joint and muscle pain, and rash. Many other febrile illnesses (e.g. Zika, Chikungunya, malaria, etc.) present with the similar symptoms and it may be hard to differentiate among illnesses without laboratory evidence.

Current Dengue Outbreak in Sri Lanka

According to the World Health Organization (WHO), Sri Lanka has seen a 4-fold increase

in dengue cases this year, compared to the same time period during 2010-2016. As of July

28, 2017, there have been 110,372 dengue cases and 301 deaths reported to the Ministry

of Health, Nutrition and Indigenous Medicine (MoH) Sri Lanka for the 2017 year, with the

most cases reported from June 30, 2017- July 7, 2017 in the Western province.

Interestingly, DENV-2 is reportedly over 50% of current specimens which have been

serotyped, but it has not been the main strain identified in individuals since 2009, which

was the genotype of DENV-1. Immunity to dengue through previous infection is specific by

serotype, so previous infection with DENV-1 does not provide immunity to DENV-2, DENV-

3, or DENV-4.

Page 2: Epidemiology Monthly Surveillance Reportorange.floridahealth.gov/.../epidemiology/_documents/surveillance-7-17.pdfmultiple countries in the Caribbean, Central and South America, and

The outbreak is concurrent with the monsoon season which brings heavy rain and flooding. With heavy rain and standing

water in urban areas, ideal mosquito (Aedes aegypti and Aedes albopictus) breeding sites are created allowing adult

mosquitos and larvae to thrive and transmit disease. The primary method of prevention has focused on eliminating

mosquito breeding sites in order to reduce the number of mosquitos present resulting in a lower number of new cases.

Residents were also encouraged to use a bed net when sleeping and practice mosquito control in and around their

home.

Geographic Distribution

Dengue is endemic in many subtropical and tropical areas of the world including Central America, South America,

Caribbean, Africa, Asia and Oceania, shown in the map below.

Prevention

All individuals traveling to endemic areas should be advised of recommended prevention methods. Clinicians should

encourage travelers to prevent dengue by avoiding mosquito bites by wearing mosquito repellent with DEET, using a

bed net when sleeping, and wearing long sleeved shirts and long pants. Patients should also be educated on the mode

of transmission and to seek medical attention if symptoms occur.

The first tetravalent dengue vaccine, Dengvaxia, was registered in Mexico in December 2015 and there are currently 5

other vaccine candidates under evaluation. The WHO recommends that countries with high burden of disease consider

introducing the vaccine into their countries. It is currently recommended for residents of endemic areas and is not

recommended for travelers.

Treatment

There is no specific treatment for dengue, so prevention is of utmost importance. Severity of symptoms will vary by patient depending on many factors including previous infection status. Symptoms can range from mild to severe, but re-infection of dengue can cause more severe symptoms including dengue hemorrhagic fever and dengue shock syndrome. Successful management of patients with dengue is attained by timely and appropriate use of supportive care by keeping the patient hydrated and using acetaminophen to control fever, avoiding aspirin and other nonsteroidal anti-inflammatory drugs because of their anticoagulant properties.

Page 2

CDC Dengue Clinical Guidance CDC Dengue Disease Information

2017 Dengue Outbreak– Sri Lanka FDOH Dengue Fever Dengue Fever World Map

Epidemiology Monthly Surveillance Report

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Page 3 Epidemiology Monthly Surveillance Report

Influenza Surveillance (data from Florida Flu Review)

Florida

In weeks 27-28, Influenza and ILI activity remained low, which is typical for this time of the year.

In weeks 27-28, one outbreak of ILI was reported.

No influenza-associated pediatric deaths were reported in weeks 27-28.

Orange County

Orange County influenza activity level for weeks 27-28 has decreased.

No influenza outbreaks were investigated in Orange County in July.

Influenza Resources: Florida Department of Health Influenza

Center for Disease Control and Prevention Weekly Influenza Activity Report

Influenza-like Illness from Emergency Department Visits in Orange County, 2013 to 2017

Influenza and ILI Outbreaks by County Week 40, 2016

through Week 28, 2017

Page 4: Epidemiology Monthly Surveillance Reportorange.floridahealth.gov/.../epidemiology/_documents/surveillance-7-17.pdfmultiple countries in the Caribbean, Central and South America, and

Page 4

Zika Virus Surveillance

Zika Virus Resources:

Florida Department of Health Latest Travel Notices

Orange County Mosquito Control CDC Healthcare Guidance

Centers for Disease Control and Prevention Local Health Department Contact Information

Epidemiology Monthly Surveillance Report

Clinician Guidance

Clinicians who suspect a patient has a Zika virus infection should:

1) Test for dengue and chikungunya viruses also due to similar geographic spread of diseases and clinical

presentation;

2) Contact their local county health department to report the disease upon suspicion. The local health department

will be able to provide consultation for laboratory testing recommendations. Local health department contact

information is available here.

National

CDC travel recommendations regarding Zika virus can be viewed here.

Differences in case counts can be attributed to surveillance reporting time lags between agencies.

On November 28, 2016, the first local Zika virus mosquito-borne case in Brownsville, TX was reported.

Florida

On August 1, 2017, the first case of sexually transmitted Zika infection was confirmed in Pinellas County. There are no reports of local transmission by mosquitos in Florida.

On June 2, the CDC removed the cautionary area designation for Miami-Dade County.

There are no longer travel recommendations related to Zika virus for Miami-Dade County, Florida. However, the level of risk for Zika virus transmission after a yellow area is removed remains unknown. Therefore individuals should continue to protect themselves by following CDC recommendations.

Orange County

No local transmission of Zika has been identified in Orange County.

Pregnant women (with or without exposure) can get tested for free at three Health Department locations in Orange County (Tues-Thurs 9:00AM-1:30PM).

Lila Mitchell Clinic: 5151 Raleigh St. Suite B

Southside: 6101 Lake Ellenor Dr.

Eastside: 12050 E. Colonial Dr. Building A Testing referrals will be given on a walk-in basis only.

Top 3 States Total Case Count

Florida 1143

New York 1042

California 454

Laboratory-confirmed symptomatic Zika virus

disease cases (2015-2017)

Travel-Related Zika Cases in FL by County

County Case Count

2016 Case Count

2017

Miami-Dade 350 37

Broward 182 17

Orange 167 12

Palm Beach 65 4

Hillsborough 46 4

Osceola 38 0

Polk 31 2

Seminole 28 2

Collier 28 4

Pinellas 25 2

Brevard 17 0

As of August 2, 2017

As of August 4, 2017

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Page 5 Epidemiology Monthly Surveillance Report

Gastrointestinal Illness Surveillance

Enteric reportable disease cases remain within seasonally expected levels.

2 GI illness outbreaks were reported to Orange County during July.

In July, there were 15 foodborne illness complaints reported to Orange County.

Gastrointestinal Illness Resources:

Florida Online Foodborne Illness Complaint Form - Public Use Florida Food and Waterborne Disease Program Florida Food Recall Searchable Database Florida Department of Health - Norovirus Resources CDC: A-Z Index for Foodborne Illness CDC: Healthy Water

Select Reportable Enteric Diseases in Orange County, Florida, July 2016 to July 2017

Gastrointestinal Illness Points of Interest:

Page 6: Epidemiology Monthly Surveillance Reportorange.floridahealth.gov/.../epidemiology/_documents/surveillance-7-17.pdfmultiple countries in the Caribbean, Central and South America, and

Arboviral Surveillance

Weekly Florida Arboviral Activity Report (Released on Mondays) Orange County Mosquito Control

Arboviral Resources:

Florida Department of Health Mosquito-Borne and Other Insect-Borne Diseases

Information

Florida Department of Health Mosquito-Borne Disease Education Materials

Florida

Additional Resources:

Four travel-associated cases of dengue have been

reported in 2017. One travel-associated case of

chikungunya was reported in 2017. No human cases of

West Nile virus (WNV) have been reported.

No counties are currently under a mosquito-borne illness

advisory or alert.

The best method of prevention is to avoid mosquito bites and to reduce mosquito breeding sites.

National

There is a CDC Level 2 (Alert) Travel Health Notice for Brownsville, TX.

International

There is a CDC Level 2 (Alert) Travel Health Notice for

multiple countries in the Caribbean, Central and South

America, Mexico, Cape Verde, Southeast Asia, and

Pacific Islands related to Zika and poor pregnancy

outcomes.

There is a CDC Level 2 Travel Health Notice for Brazil

related to the transmission of Yellow Fever virus.

There is a CDC Level 1 (Watch) Travel Health Notice for

multiple countries in the Caribbean, Central and South

America, and Mexico, related to the transmission of

chikungunya virus.

Page 6 Epidemiology Monthly Surveillance Report

Orange County

No locally acquired cases of Zika virus, West Nile virus, dengue virus, chikungunya virus, St. Louis encephalitis virus, or Eastern

equine encephalitis virus have been identified in Orange County in 2017.

Three travel-related cases of Zika virus were reported in July 2017. In total, there are 12 travel-related cases of Zika virus in

2017.

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Outbreaks in Orange County, FL

*** All Data are Preliminary ***

In July 2017, there were 2 Gastrointestinal Illness outbreaks reported to Orange

County.

One was associated with exposure to a pet store chain.

One occurred in a daycare.

There was one outbreak of Legionnaires’ disease associated with a skilled nursing

facility.

There was one suspected streptococcal pharyngitis outbreak in a daycare.

A VIM-producing Pseudomonas outbreak occurred in a Long Term Acute Care

Hospital.

Page 7 Epidemiology Monthly Surveillance Report

Number of Outbreaks Reported in Orange County, FL, by Month from 2013 - 2017

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Page 8 Epidemiology Monthly Surveillance Report

*** All Data are Preliminary ***

ORANGE All Counties

Disease July Cumulative

(YTD) July

Cumulative (YTD)

2017 Median

5YR 2017

Median 5YR

2017 Median

5YR 2017

Median 5YR

Campylobacteriosis 22 16 118 76 453 335 2648 1875

Carbon Monoxide Poisoning 4 0 10 3 20 17 131 107

Creutzfeldt-Jakob Disease (CJD) 0 0 1 0 1 1 13 14

Cryptosporidiosis 4 7 14 14 48 56 247 271

Cyclosporiasis 1 1 2 1 27 21 51 25

Escherichia coli: Shiga Toxin-Producing (STEC) Infection 3 2 16 11 80 53 406 281

Giardiasis: Acute 6 7 27 36 91 99 634 611

Haemophilus influenzae Invasive Disease 0 1 10 8 26 14 183 188

Hemolytic Uremic Syndrome (HUS) 0 0 1 0 0 1 8 4

Hepatitis A 0 0 7 2 26 12 164 74

Hepatitis B: Acute 4 1 21 8 72 32 443 229

Hepatitis B: Chronic 32 32 273 239 412 396 3260 2770

Hepatitis B: Surface Antigen in Pregnant Women 6 6 41 40 42 52 281 295

Hepatitis C: Acute 2 1 12 3 37 19 207 122

Hepatitis C: Chronic 109 123 871 860 2150 2448 15456 17286

Hepatitis C: Perinatal 0 0 0 0 0 0 7 0

Influenza-Associated Pediatric Mortality 0 0 1 0 0 0 12 3

Lead Poisoning 1 1 13 14 77 80 709 491

Legionellosis 3 2 25 9 50 32 281 178

Listeriosis 0 0 2 1 6 5 31 21

Lyme Disease 1 0 6 1 41 32 190 82

Malaria 0 1 2 4 14 7 36 40

Measles (Rubeola) 0 0 1 0 0 0 4 5

Meningitis: Bacterial or Mycotic 0 0 1 2 10 14 67 89

Meningococcal Disease 1 0 1 0 3 2 16 30

Mercury Poisoning 0 0 1 0 2 1 23 9

Mumps 0 0 1 0 12 1 46 13

Neurotoxic Shellfish Poisoning 0 0 2 0 0 0 2 0

Pertussis 1 3 20 19 48 77 250 344

Q Fever: Acute (Coxiella burnetii) 0 0 1 0 0 0 2 1

Rabies: Possible Exposure 3 5 44 53 263 299 1912 1736

Salmonellosis 38 31 163 141 662 724 3081 2940

Shigellosis 9 6 59 49 157 172 753 1203

Strep pneumoniae Invasive Disease: Drug-Resistant 2 0 13 16 12 14 163 297

Strep pneumoniae Invasive Disease: Drug-Susceptible 1 1 14 15 23 27 241 335

Typhoid Fever (Salmonella Serotype Typhi) 1 0 2 0 4 1 30 7

Varicella (Chickenpox) 2 2 37 11 52 36 416 460

Vibriosis (Other Vibrio Species) 1 0 1 0 8 2 37 6

Vibriosis (Vibrio alginolyticus) 1 0 4 2 10 8 45 36

Vibriosis (Vibrio vulnificus) 0 0 1 0 9 6 17 15

Zika Virus Disease and Infection- Non-Congenital 0 0 17 0 14 0 172 0

Total 258 249 1856 1638 4962 5096 32675 32493

Page 9: Epidemiology Monthly Surveillance Reportorange.floridahealth.gov/.../epidemiology/_documents/surveillance-7-17.pdfmultiple countries in the Caribbean, Central and South America, and

Florida Department of Health: Since 2007, the Florida Department of Health has

operated the Electronic Surveillance System for the

Early Notification of Community-based Epidemics

(ESSENCE-FL), a state-wide electronic bio-

surveillance system. The initial scope of ESSENCE

was to aid in rapidly detecting adverse health events

in the community based on Emergency Department

(ED) chief complaints. In the following years,

ESSENCE capabilities have continually evolved to

currently allow for rapid data analysis, mapping, and

visualization across several data sources, including

ED record data, Merlin reportable disease data,

Florida Poison Information Network consultations,

and Florida Office of Vital Statistics death records.

The majority of the information presented in this

report comes via ESSENCE. Florida currently has

228 emergency departments and 35 urgent care

centers reporting to ESSENCE-FL for a total of 263

facilities.

Epidemiology Monthly Surveillance Report

Hospital linked to ESSENCE

Florida Hospital Centra Care Clinic linked to ESSENCE

Other Disease Resources

In the structure of DOH-Orange, tuberculosis, sexually transmitted infections,

and human immunodeficiency virus are housed in separate programs from the

Epidemiology Program. We recognize the importance of these diseases for our

community partners and for your convenience have provided links for

surveillance information on these diseases in Florida and Area 7 HIV & AIDS

Program (Brevard, Orange, Osceola, and Seminole Counties).

Page 9

Zoonotic Transmission of Campylobacter

While Campylobacter gastroenteritis is commonly associated with foodborne transmission such as

consuming raw or undercooked poultry, zoonotic transmission has also been implicated and should be

considered during patient interviews. In the US, 14 cases of campylobacteriosis per 100,000 persons are

diagnosed each year, making it one of the most common causes of diarrheal illness.

Symptomatic and asymptomatic animals such as puppies, kittens, and birds are natural carriers of Campylobacter, and therefore shed the bacteria in their stool. In humans, infection with Campylobacter bacteria may cause diarrhea which is often bloody, and vomiting, abdominal pain, and fever. Those at a greater risk for developing illness include children, older adults, and immunosuppressed individuals. Vigilant hand washing after contact with animals or animal feces is recommended to prevent illness.

Resources: https://www.cdc.gov/foodsafety/diseases/campylobacter/index.html

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197190/

Page 10: Epidemiology Monthly Surveillance Reportorange.floridahealth.gov/.../epidemiology/_documents/surveillance-7-17.pdfmultiple countries in the Caribbean, Central and South America, and

The Epidemiology Program conducts disease surveillance and investigates, controls, and prevents

infectious diseases and conditions that are reported to DOH-Orange.

Surveillance is primarily conducted through passive reporting from the medical community as

required by Chapter 381, Florida Statutes.

Data are collected and analyzed to track disease trend, and identify outbreaks and unusual

occurrences for response and mitigation, to identify targets for prevention and reduction efforts.

In cooperation with the Office of Emergency Operations, the Epidemiology Program conducts

syndromic and influenza-like-illness surveillance activities. Syndromic surveillance was added to the

disease reporting process as an active method of determining activities in the community that could

be early indicators of outbreaks and bioterrorism.

Our staff ensure that action is taken to prevent infectious disease outbreaks from occurring in

Orange County communities and area attractions. Along with many public and private health

groups, we work for the prevention of chronic and long-term diseases in Central Florida.

Epidemiology Program

6101 Lake Ellenor Drive

Orlando, Florida 32809

Phone: 407-858-1420

Fax: 407-858-5517

http://orange.floridahealth.gov/

F l or i da D e p ar t m e nt o f H e a l th i n Or a n g e Co u n t y

ALL DATA ARE PROVISIONAL

Issue Contributors

Alvina Chu, MHS

Epidemiology Program Manager

Taylor Campion, MPH Epidemiologist

Kathy Abusager, MPH

Epidemiologist

Ashley Vineyard, MPH Epidemiologist

Sign up for

Electronic Health Alerts & Epidemiology

Monthly Surveillance Reports

Email Contact Information to:

[email protected]

Page 10 Epidemiology Monthly Surveillance Report