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Enzymes & Your Body By Malinda Pires
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Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Dec 21, 2015

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Page 1: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Enzymes & Your Body

By Malinda Pires

Page 2: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Enzymes are Catalyst

• Enzymes speed up chemical reactions.•Animation Menu•Enzymes are catalyst to over 4000 biochemical reactions!

Life Sciences-HHMI Outreach. Copyright 2009 President and Fellows of Harvard College

http://en.wikipedia.org/wiki/File:GLO1_Homo_sapiens_small_fast.gif

Page 3: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Activation Energy

Enzymes work by lowering the activation energy needed to start a chemical reaction.

http://en.wikipedia.org/wiki/File:Activation_energy.svg

Life Sciences-HHMI Outreach. Copyright 2009 President and Fellows of Harvard College

Page 4: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Enzymes are Reusable

• Enzymes are reusable molecules found in living things.

• Animation Menu

http://en.wikipedia.org/wiki/File:GLO1_Homo_sapiens_small_fast.gif

Life Sciences-HHMI Outreach. Copyright 2009 President and Fellows of Harvard College

Page 5: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Classifying Enzymes• There are 4 major categories of macromolecules: carbohydrates, lipids, proteins, &

nucleic acids

• Most enzymes belong to the class of proteins.• However, there are a few catalytic RNA molecules.

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QuickTime™ and aTIFF (Uncompressed) decompressor

are needed to see this picture.

Life Sciences-HHMI Outreach. Copyright 2009 President and Fellows of Harvard College

1 http://en.wikipedia.org/wiki/File:Glucose-2D-skeletal.png 2 http://en.wikipedia.org/wiki/File:Phospholipids_aqueous_solution_structures.svg 3 http://en.wikipedia.org/wiki/File:Mouse-cholera-antibody-1f4x.png 4 http://en.wikipedia.org/wiki/File:Benzopyrene_DNA_adduct_1JDG.png

Page 6: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Naming Enzymes

• Take the name of the substrate the enzyme works on and add the suffix -ase

• Example: Lactose Lactase

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Life Sciences-HHMI Outreach. Copyright 2009 President and Fellows of Harvard College

http://en.wikipedia.org/wiki/File:Lactase.jpg

Page 7: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Enzyme Form and Function

• Lock & key Model: The shape of an enzyme allows it to do a specific job much like a lock and key.

• Specificity - Animation Menu

Life Sciences-HHMI Outreach. Copyright 2009 President and Fellows of Harvard College

QuickTime™ and aTIFF (Uncompressed) decompressorare needed to see this picture.QuickTime™ and aTIFF (Uncompressed) decompressor

are needed to see this picture.

http://en.wikipedia.org/wiki/File:Wardedlock.jpghttp://en.wikipedia.org/wiki/File:Llave_bronce.jpg

Page 8: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Induced Fit Model• Enzymes can form to the shape of its

substrate.

http://en.wikipedia.org/wiki/File:Induced_fit_diagram.svg

Life Sciences-HHMI Outreach. Copyright 2009 President and Fellows of Harvard College

Page 9: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Denaturing Enzymes

• When an enzyme is denatured it is damaged.

• Denaturing changes the shape.

• Without the correct shape enzymes won’t function properly.

• HOW are enzymes denatured?– Temperature Animation Menu

– pH

Life Sciences-HHMI Outreach. Copyright 2009 President and Fellows of Harvard College

Page 10: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Enzyme Inhibitors

• Chemicals that prevent the enzyme from working.• Inhibitors decrease the enzyme reaction rate.

Life Sciences-HHMI Outreach. Copyright 2009 President and Fellows of Harvard College

http://en.wikipedia.org/wiki/File:Competitive_inhibition.svg

Page 11: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Enzyme Activators• Chemicals that help the enzyme work.• Activators increase the enzyme reaction rate.

Life Sciences-HHMI Outreach. Copyright 2009 President and Fellows of Harvard College

X

Activator

SubstrateBindingSite

ActiveSite

Page 12: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

Enzymes are used all over your body!

Life Sciences-HHMI Outreach. Copyright 2009 President and Fellows of Harvard College

http://en.wikipedia.org/wiki/File:Digestive_system_diagram_en.svg

Page 13: Enzymes & Your Body By Malinda Pires. Enzymes are Catalyst Enzymes speed up chemical reactions. Animation Menu Enzymes are catalyst to over 4000 biochemical.

http://upload.wikimedia.org/wikipedia/commons/thumb/6/6f/Major_digestive_enzymes.png/750px-Major_digestive_enzymes.png

Life Sciences-HHMI Outreach. Copyright 2009 President and Fellows of Harvard College