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MR Enterography Cynthia Santillan, MD University of California San Diego Examination performed after ingestion of a large volume of oral contrast meant to distend the small bowel Combines assessment of bowel wall with ability to visualize extraluminal disease Overview MR Enterography Inflammatory bowel disease Obscure gastrointestinal bleeding Suspected small bowel tumor Diffuse bowel disease Intermittent SBO Indications Indications for Enterography Evaluate non-accessible bowel Less invasive procedure Surveillance IBD activity Active vs stenotic vs normal Ulcers, sinus tract, fistula, abscess Length/location of involvement Motility Indications Goals of Imaging product.fujifilm.com.au Technique Instructions Describe exam! Clear liquids after midnight NPO 2 hours prior (Colon prep) (Low Mn diet) Goals Decrease particulate material in bowel Decrease T1 bright material in bowel Preparation Patient Instructions
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Educational Symposia - Overview MR Enterography · 2016. 10. 28. · Obscure gastrointestinal bleeding Suspected small bowel tumor Diffuse bowel disease Intermittent SBO Indications

Jul 31, 2021

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Page 1: Educational Symposia - Overview MR Enterography · 2016. 10. 28. · Obscure gastrointestinal bleeding Suspected small bowel tumor Diffuse bowel disease Intermittent SBO Indications

MR Enterography

Cynthia Santillan, MD University of California San Diego

Examination performed after ingestion of a large volume of oral contrast meant to distend the small bowel

Combines assessment of bowel wall with

ability to visualize extraluminal disease

Overview

MR Enterography

Inflammatory bowel disease Obscure gastrointestinal bleeding

Suspected small bowel tumor Diffuse bowel disease

Intermittent SBO

Indications

Indications for Enterography

Evaluate non-accessible bowel Less invasive procedure Surveillance

IBD activity Active vs stenotic vs normal Ulcers, sinus tract, fistula, abscess Length/location of involvement

Motility

Indications

Goals of Imaging

product.fujifilm.com.au

Technique

Instructions

Describe exam! Clear liquids after midnight NPO 2 hours prior (Colon prep) (Low Mn diet)

Goals

Decrease particulate material in bowel Decrease T1 bright material in bowel

Preparation

Patient Instructions

Page 2: Educational Symposia - Overview MR Enterography · 2016. 10. 28. · Obscure gastrointestinal bleeding Suspected small bowel tumor Diffuse bowel disease Intermittent SBO Indications

Oral Contrast

Low T1/T2: Iron containing compounds

High T1/T2: Dilute Gd, Fruit juices, Milk (low HU)

Options

Low T1/T2

High T1/T2

Low T1/High T2:

Water – well-tolerated, cheap, rapidly absorbed

PEG, Low dose Ba with sorbitol, methylcellulose – rapid transit, slowly absorbed, patient discomfort

Options

Oral Contrast

Delay of at least 40 min to ensure contrast has reached the terminal ileum

Most protocols require 1.5 – 2.0 liters

Current UCSD protocol: 60 min – 500mL 40 min – 500mL 20 min – 500mL Table – 400mL water

Administration

Oral Contrast

SSFSE SSFP

Oral Contrast

Inadequate distention can: Simulate bowel wall thickening

Oral Prep Goals

Oral Prep Goals

Oral Contrast

Inadequate distention can: Simulate bowel wall hyperenhancement

Spasmolytic

Glucagon (Buscopan)

IM

Split dose IV total 1mg

Medication

Performing Exam

Page 3: Educational Symposia - Overview MR Enterography · 2016. 10. 28. · Obscure gastrointestinal bleeding Suspected small bowel tumor Diffuse bowel disease Intermittent SBO Indications

Multiplanar - Coronals critical!

Cine Imaging – SSFP

Spasmolytic

Steady state free precession (SSFP) +/- Fat Sat

Single shot fast spin echo (SSFSE) +/- Fat Sat

Diffusion

3D T1 weighted Fat Sat Pre contrast & Dynamic Coronal

(High resolution imaging of pelvis)

Performing Exam

MR Sequences Multiplanar - Coronals critical!

SSFP – Coronal, check distension

Cine Imaging - SSFP

Spasmolytic

SSFSE – Coronal, Axial (+/-Fat Sat)

Diffusion - Axial

3D T1 weighted Fat Sat Pre contrast & Dynamic Coronal

T1 Weighted Fat Sat - Axial

Performing Exam

MR Sequences – UCSD IBD

Multiplanar - Coronals critical!

SSFP – Coronal, check distension

Spasmolytic

SSFSE – Coronal, Axial

SSFP – Axial

3D T1 weighted Fat Sat Pre contrast & Dynamic Coronal

T1 Weighted Fat Sat - Axial

Performing Exam

MR Sequences – UCSD nonIBD Reduce volume to be imaged in coronal plane

Bowel separation

Improved distention

Respiratory motion artifact

Prone

Positioning

Motility

Coronal SSFP

Prior to spasmolytics

Assess for: Fixed stenoses or

dilation Adhesions

Incremental value TBD

Performing Exam

Spasmolytic

Decrease intraluminal flow artifacts

Medication

Performing Exam

pre-Glucagon SSFSE

post-Glucagon SSFSE

post-Glucagon SSFP

Page 4: Educational Symposia - Overview MR Enterography · 2016. 10. 28. · Obscure gastrointestinal bleeding Suspected small bowel tumor Diffuse bowel disease Intermittent SBO Indications

Assessing intraluminal low signal

Sequence Selection

Performing Exam

SSFSE SSFP

Performing Exam

Assessing intraluminal low signal

Sequence Selection

SSFSE SSFP

Inflammatory bowel disease Obscure gastrointestinal bleeding

Suspected small bowel tumor Diffuse bowel disease

Intermittent SBO

Indications

Indications for Enterography

Considerations for CT vs MR

Young patients Frequent imaging Sinus tracts/fistula Perirectal/anal disease Iodinated contrast issues

Indications

Inflammatory Bowel Disease

Activity Indices

Crohn Disease Activity Index (CDAI) Clinical, current standard

Crohn Disease Endoscopic Index of Severity (CDEIS)

Indications

Inflammatory Bowel Disease

MR Indices

>15 MR indices have been published Magnetic Resonance Index of Activity (MaRIA) – Relative contrast enhancement, wall thickening, ulcer, edema Crohn’s Disease MRI Index (CDMRI) – Enhancement, wall thickening, mural T2, perimural T2 Clermont Score – DWI/ADC, wall thickening, edema, ulcer

Indications

Inflammatory Bowel Disease

Page 5: Educational Symposia - Overview MR Enterography · 2016. 10. 28. · Obscure gastrointestinal bleeding Suspected small bowel tumor Diffuse bowel disease Intermittent SBO Indications

Inflammatory Bowel Disease

Acute TI Inflammation Acute TI Inflammation

Inflammatory Bowel Disease

Acute TI Inflammation

Inflammatory Bowel Disease

Acute Colon Inflammation

Inflammatory Bowel Disease

b=500

b=1000

Ulcerations

Inflammatory Bowel Disease

Ulceration

Inflammatory Bowel Disease

Page 6: Educational Symposia - Overview MR Enterography · 2016. 10. 28. · Obscure gastrointestinal bleeding Suspected small bowel tumor Diffuse bowel disease Intermittent SBO Indications

Sinus Tracts

Inflammatory Bowel Disease

Chronic Strictures

Inflammatory Bowel Disease

Complex Sinus Tracts

Inflammatory Bowel Disease

Sinus Tract with Abscess

Inflammatory Bowel Disease

Small Bowel Tumor

Patients with small bowel tumors present with a variety of symptoms, depending on the location, size, & etiology of the lesion

Small Bowel Tumors Carcinoid Adenocarcinoma Gastrointestinal Stromal Tumor (GIST) Lipoma Lymphoma Metastatic Disease

OGIB/Tumor

Inflammatory Fibroid Polyp OGIB/Tumor

Page 7: Educational Symposia - Overview MR Enterography · 2016. 10. 28. · Obscure gastrointestinal bleeding Suspected small bowel tumor Diffuse bowel disease Intermittent SBO Indications

Peutz-Jeghers OGIB/Tumor

Peutz-Jeghers OGIB/Tumor

Indications

Diffuse Small Bowel Disease

Diffuse Disease

Cronkhite-Candida

Diffuse Disease

Celiac Disease

Indications

Technique

Interpretation

Summary

MR Enterography