EBM Journal reading ? Presented by R3 - 2012/05/21
EBM Journal reading
?
Presented by R3-2012/05/21
ScenarioR ~
Background knowledge
–
– 50 – 80
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1995 1 2004 6.7
300
( )
()
:
( )
Background knowledgeProbiotics
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– 1965 Lilly Stillwell– Probiotics ”for life”WHO
LactobacillusBacillus spp.,
Bifidobacterium spp., Propionibacterium spp.
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Acquire
Appraisal
Apply
Audit
ASK?
Pregnant womenP
ProbioticsI
PlaceboC
Children’s incidence of atopic dermatitis O
Acquire
Database : PubMed
Key word: Probiotics, atopic dermitis, pregnancy
Epidemiology • Volume 23, Number 3, May 2012. Meta-Analysis
Appraisal
Validity
Importance
Practicability
CASP for meta-analysisCritical Appraisal Skills Programmer (CASP)
1. Did the review ask a clearly-focused question? 2. Did the review include the right type of study? 3. Did the reviewers try to identify all studies? 4. Did the reviewers assess the quality of the included studies? 5. If the results of the studies have been combined, was it reasonable to do so? 6. How are the results presented and what is it? 7. How precise are these results? 8. Can the results be applied to the local population? 9. Were all important outcomes considered? 10. Should policy or practice change as a result of the evidence contained in this review?
Validity
AppraisalDid the review ask a clearly-focused question - Yes
AppraisalDid the review include the right type of study- Yes
AppraisalDid the reviewers try to identify all studies - Yes
AppraisalDid the reviewers assess the quality of the included studies - Yes
AppraisalIf the results of the studies have been combined, was it reasonable to do so
Importance
Result
Result
Result
Appraisal -Importance
RR(95%CI)=0.79(0.71~0.88)NNT(95%CI)=5
Practicability
Apply
Can the results be applied to the local population? – Yes
Were all important outcomes considered? – Yes
Should policy or practice change as a result of the evidence contained in this review? – ?
Apply
Practical in Practice?
?
?
?
?
33
Audit
Conclusion
Limitation
mechanism
34
THANKS FOR YOUR ATTENTION