Early results of ex vivo cultivated autologous limbal epithelium transplantation for limbal stem cell deficiency Himanshu Matalia, MD 1,2 Arokiaraj Vincent, MSc 2 D Kamesh, MSc 2 Authors have no financial interest Poster 610 1. Cornea & Refractive Services, Narayana Nethralaya 2. Narayana Nethralaya Stem Cell Research Laboratory Narayana Nethralaya Narayana Health City Super Specialty Eye Hospital & Post Graduate Institute of Ophthalmology Bangalore - INDIA
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Early results of ex vivo cultivated autologous limbal epithelium transplantation for limbal stem cell deficiency Himanshu Matalia, MD 1,2 Arokiaraj Vincent,
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Early results of ex vivo cultivated autologous limbal
epithelium transplantation for limbal stem cell deficiency
Most recent technique Best for unilateral LSCD Autologous cells, no immune suppression required No risk at donor site RepeatableLimitations Availability of the tissue culture facility Long-term outcome awaited
Pellegrini et al Lancet 1997; 349: 900-993 Tsai RJ, Li LM, Chen JK. N Engl J Med 2000;343(2):86-93Schwab et al Cornea 2000;19(4):421-6Koizumi et al IOVS 2002;43(7):2114-21
Purpose
• To describe the early results of our technique of ex vivo cultivated autologous limbal epithelial transplantation (CALET) for limbal stem cell deficiency (LSCD).
Methods
• Prospective, non-randomized interventional case series
• 14 eyes of 14 consecutive patient with LSCD underwent CALET from October