Jun 12, 2015
Javed IqbalJaved IqbalFCPS, FRCSFCPS, FRCS
Professor Of SurgeryProfessor Of Surgery
Quaid-e-Azam Medical Quaid-e-Azam Medical College, BahawalpurCollege, Bahawalpur
Deep vein thrombosisDeep vein thrombosis
It is a serious diseaseIt is a serious disease
Sudden deathSudden death Long term morbidityLong term morbidity
• Chronic venous insufficiency Chronic venous insufficiency • UlcerationUlceration
Its incidence is Its incidence is underestimatedunderestimated
10% of all hospitalized deaths 10% of all hospitalized deaths are due to DVT/PEare due to DVT/PE
Virchow’s triadVirchow’s triad
Change in vessel wallChange in vessel wall• InjuryInjury• InflammationInflammation
StagnationStagnation• Hospitalized patientsHospitalized patients
Increased coagubilityIncreased coagubility• SurgerySurgery• MalignancyMalignancy• ThrombophiliaThrombophilia
ThrombophilliaThrombophillia
Anti-thrombin III deficiencyAnti-thrombin III deficiency Protein C and S deficiencyProtein C and S deficiency Anti-phospholipid antibodiesAnti-phospholipid antibodies DysfibrogenaemiaDysfibrogenaemia
Predisposing factors/situationsPredisposing factors/situations
Old ageOld age prolonged surgical proceduresprolonged surgical procedures Procedures on Hip and pelvisProcedures on Hip and pelvis SpleenectomySpleenectomy Gyaenacological proceduresGyaenacological procedures Stroke / and other neurological Stroke / and other neurological
ailmentsailments
Myocardial Infarction / CCFMyocardial Infarction / CCF Oral contraceptives / steroidsOral contraceptives / steroids ObesityObesity Varicose veinsVaricose veins PregnancyPregnancy malignancymalignancy
Air TravelAir Travel
ImmobilityImmobility HypoxiaHypoxia Decreased cabin pressureDecreased cabin pressure
10 % of all passengers of long flights
E-thrombosisE-thrombosis
What to do?What to do?
Don’t let it happenDon’t let it happen
ProphylaxisProphylaxis
Every unit must have its Every unit must have its own DVT prophylaxis policyown DVT prophylaxis policy
According to local According to local circumstancescircumstances
The most important point is The most important point is to keep in mind that DVT to keep in mind that DVT
does existdoes exist
The standard guideline is to The standard guideline is to define and identify the risk define and identify the risk
groups groups
Low RiskLow Risk
Young patients with minor ailment Young patients with minor ailment having no risk factor and undergoing having no risk factor and undergoing a procedure of less than an houra procedure of less than an hour
Moderate riskModerate risk
Patient over 40 with debilitating Patient over 40 with debilitating illness illness
Patient above 40 undergoing major Patient above 40 undergoing major surgical proceduresurgical procedure
But there is no risk factorBut there is no risk factor
High RiskHigh Risk
Patient over 40Patient over 40 Serious medical illnessSerious medical illness Major surgeryMajor surgery Additional risk factorAdditional risk factor
Principals of PreventionPrincipals of Prevention
Minimizing the Minimizing the correctable risk factorscorrectable risk factors
1
Mechanical measuresMechanical measures
2
Graduated compression dressing Graduated compression dressing (TEDS)(TEDS)
Sequential pneumatic compressionSequential pneumatic compression Early ambulation Early ambulation
Pharmacological Pharmacological interventionintervention
3
Low dose (sub-cut) heparin : 5000 Low dose (sub-cut) heparin : 5000 units bidunits bid
Low molecular weight heparinLow molecular weight heparin
All moderate and high risk All moderate and high risk patients must have some patients must have some
DVT prophylaxisDVT prophylaxis
If DVT does occur!If DVT does occur!
Symptoms/signs/labsSymptoms/signs/labs
Leg painLeg pain SwellingSwelling RednessRedness FeverFever Increased TLCIncreased TLC
D-DimerD-Dimer
Doppler studiesDoppler studies
55% of DVT is in pelvic 55% of DVT is in pelvic veinsveins
TreatmentTreatment
Anticoagulation: HepranizationAnticoagulation: Hepranization Elevation of limbElevation of limb MoniteringMonitering
Pulmonary embolismPulmonary embolism
Massive embolismMassive embolism
Massive embolismMassive embolism
Medium vessel Medium vessel embolismembolism
Small vessel embolismSmall vessel embolism
DyspnoeaDyspnoea CoughCough HaemoptysisHaemoptysis HypoxiaHypoxia Acute right shift on ECGAcute right shift on ECG X-ray chestX-ray chest
ManagementManagement
HepranizationHepranization Standard resuscitationStandard resuscitation AntibioticsAntibiotics
Long term anticoagulationLong term anticoagulation
Thank you