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Ducts of Pancreas
• No striated ducts• Intercalated ducts = intralobular ducts• Intercalated ducts drain directly into
interlobular ducts – simple squamous or low columnar epithelium
• Main pancreatic ducts (Wirsung and Santorini) – simple columnar epithelium
Pancreatic Juice Secretion
• Secretin – Secreted in response to HCl– Produces HCO3-rich secretion to neutralize acidic
chyme (pancreatic enzymes function at optimal neutral pH)
• Cholecystokinin (CCK)– In response to the entry of proteins and fats– Enzyme-rich fluid which act mainly on extrusion of
zymogen granules
Gallbladder
• Hollow, pear-shaped organ attached to the lower surface of the liver
• Lies in gallbladder fossa
• Can store 30-50 mL of bile
Gallbladder
• Fundus• Body • Neck• Cystic duct
Gallbladder
• Main functions:– Stores bile– Concentrates bile (water absorption) – Releases bile when necessary into the digestive
tract
• Bile – fat emulsifier
Gallbladder Wall
• Mucosa:– Have anastomosing folds, no villus– Simple columnar epithelium without goblet cells– Lamina propria