Rate of discard of blood Rate of discard of blood and its components as a and its components as a quality indicator for blood quality indicator for blood utilization in a tertiary utilization in a tertiary care haemato-oncology care haemato-oncology centre centre Dr Shashank Ojha, Dr Sumathi S H, Amol Tirlotkar , Dr S B Rajadhyaksha Advanced Centre for Treatment, Research & Education in Cancer, Kharghar, Navi Mumbai
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Dr Shashank Ojha, Dr Sumathi S H, Amol Tirlotkar , Dr S B Rajadhyaksha
Rate of discard of blood and its components as a quality indicator for blood utilization in a tertiary care haemato -oncology centre. Dr Shashank Ojha, Dr Sumathi S H, Amol Tirlotkar , Dr S B Rajadhyaksha Advanced Centre for Treatment, Research & Education in Cancer, Kharghar, Navi Mumbai. - PowerPoint PPT Presentation
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Rate of discard of blood and its Rate of discard of blood and its components as a quality indicator components as a quality indicator for blood utilization in a tertiary for blood utilization in a tertiary care haemato-oncology centrecare haemato-oncology centre
Dr Shashank Ojha, Dr Sumathi S H, Amol Tirlotkar, Dr S B Rajadhyaksha
Advanced Centre for Treatment, Research & Education in Cancer, Kharghar, Navi Mumbai
BACKGROUNDBACKGROUNDThe rate of discard of blood components
serve as a quality indicator, for implementation of corrective measures to rationalise blood utilization and inventory management.
Determination of quality indicators requires thorough exploration of the processes underlying particular service, assessment of the risk and frequency of particular problem, and the possibilities of improvement.
Corrective Actions
Improvements
Quality Indicators for Blood Utilization
AIMAIMTo determine the rate of discard of
blood and blood components as well as blood utilization
And Reasons for discard of blood and
blood components
STUDY DESIGN & METHODSSTUDY DESIGN & METHODS
A Six years (2006-2011) retrospective data
Following rates were assessed for their mean annual trends (%)◦ Unit expiration◦ Unit discard (Wastage)◦ Reason for discard◦ Cross-match to transfusion (C:T) ratio
Discarded blood components accounts for the lost production output, thus should not be ignored.
The Mean annual discard rate was higher in our study. However, there has not been any guidelines established in the literature.
The mean annual non-infectious discard rate was higher than the mean annual infectious discard rate.
This is because of stringent donor screening & inclusion of sensitive methods for TTI testing.
DISCUSSIONDISCUSSION
The highest mean annual discard rate recorded for RDP followed by FFP then WB & PRBC & lowest for SDP.
In platelets, expiration rate was high due to short shelf life and hence were discarded, whereas SDP’s were used judicially.
Components are held a longer time in quarantine, which may contribute to outdating of PLTs.
DISCUSSIONDISCUSSION
In our centre, FFP’s were not required as much, hence, the higher discard in 2007.
After 2007, FFP’s were send to fractionation centre quarterly.
Due to 35 day shelf life of WB, apt utilization was not possible as blood centre cannot generate request.
Since our institutional bed size increased in 2009 (82 bed hospital now), over blood stocking from camps was responsible for discard.
DISCUSSIONDISCUSSION
In non-infectious, the cause for discard was major due to expiration (11.5%) than others.
This is in sharp contrast to expiry rates of 5.8-6.4% quoted by Q-Probes study while evaluating 1,639 hospitals throughout United States4.
This is because in Q-Probes study, expiry rate was calculated from units which were received by hospitals from collection centres and were not utilized during the prescribed time interval.
DISCUSSIONDISCUSSION
Mean Annual trend of expiration of RDP’s was similar with most of the studies. Sullivan et al.3
1/5th of produced PLT concentrates has been reported to become outdated and the expiration rate was more than 25% for random donor PLTs and more than 10% for aphaeresis-PLTs in every tenth blood bank of 1639 U.S. hospitals studied5.
DiscussionDiscussion
Mean annual C:T ratio was lower than 2.0 or less by monitoring requests for blood components.
As per our study highest number of infectious donor blood wastage is due to HbsAg positive.
This is due to high prevalence of HBsAg in healthy population as compared to HIV & HCV. However, it is showing a downward trend with the use of HBsAg vaccination.
DISCUSSIONDISCUSSION
CORRECTIVE MEASURESCORRECTIVE MEASURESLaunched by QMpersonnel engagement and motivation
for implementation of corrective measures.
Effectiveness of measures taken for responsible management of blood products on stock
- planning of blood collections- planning of manufacture- collaboration with clinicians
Mean annual RBC wastage can be lowered by exchanging units on credit-debit basis with other blood centres.
Rationale utilization of FFP by sending units to NPFC.
Performing the concept of common cross-match to further conserve and maintain inventory.
Training of personnel for improving the collection procedures.
Use of automated bio-mixers to reduce causes of improper collections
CORRECTIVE MEASURESCORRECTIVE MEASURES
Processing of WB for further component preparation.
Adequate spacing in organization of voluntary blood camp.
Collaboration with clinicians to monitor request for blood component therapy.
CORRECTIVE MEASURESCORRECTIVE MEASURES
CONCLUSIONCONCLUSIONRegular audit of blood utilization and
discard rate with simple mathematical models serve as an important tool for accomplishment of the quality goals.
Since blood centers cannot regulate demand, the stochastic need for blood components can be achieved by production, planning and improving inventory management to minimize discard rate.
Quality indicators for blood establishment can be done by exchange of experiences with high level of transparency & comparing the trends with corrective measures1.
REFERENCESREFERENCES1. T. Vuk. Quality indicators: a tool for quality monitoring
and improvement. ISBT Science Series (2012) 7, 24–28
2. Rossi’s Principle of Transfusion Medicine, fourth ed.
3. Sullivan MT, Wallace EL et al. Blood collection and transfusion in the United States in 1999. Transfusion 2005;45:141-8.
4. Novis DA et al. Three College of American Pathologists Q-Probes Studies of 12 288 404 Red Blood Cell Units in 1639 Hospitals. Arch Pathol Lab Med—Vol 126, February 2002
5. David A. Novis et al. Quality Indicators of Fresh Frozen Plasma and Platelet Utilization. Arch Pathol Lab Med—Vol 126, May 2002