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Dr. Hardeep Singh Malhotra MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology, King George’s Medical University, Lucknow Epilepsy
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Dr. Hardeep Singh Malhotra MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

Jan 01, 2016

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Epilepsy. Dr. Hardeep Singh Malhotra MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology, King George’s Medical University, Lucknow. MCQ-1. When do you label a “seizure” as “epilepsy”? Presence of family history >1 unprovoked seizure >1 provoked seizure - PowerPoint PPT Presentation
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Page 1: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

Dr. Hardeep Singh Malhotra MD, DM, FIACM, MNAMS

Associate Professor,Department of Neurology,King George’s Medical University, Lucknow

Epilepsy

Page 2: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-1

• When do you label a “seizure” as “epilepsy”?– Presence of family history– >1 unprovoked seizure– >1 provoked seizure– >2 provoked seizures

Page 3: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-1

• When do you label a “seizure” as “epilepsy”?– Presence of family history– >1 unprovoked seizure– >1 provoked seizure– >2 provoked seizures

Page 4: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-2

• All of the following are excitatory neurotransmitters except:– AMPA– NMDA– GABA– Glutamate

Page 5: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-2

• All of the following are excitatory neurotransmitters except:– AMPA– NMDA– GABA– Glutamate

Page 6: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-3

• Which of the following abnormality is associated with ‘Generalized Epilepsy & Febrile Seizures plus’ syndrome?– Sodium channel mutations– Calcium channel mutations– Potassium channel mutations– Chloride channel mutations

Page 7: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-3

• Which of the following abnormality is associated with ‘Generalized Epilepsy & Febrile Seizures plus’ syndrome?– Sodium channel mutations– Calcium channel mutations– Potassium channel mutations– Chloride channel mutations

Page 8: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-4

• Which of the following abnormality is associated with ‘Juvenile Myoclonic Epilepsy’?– Sodium channel mutations– Calcium channel mutations– Potassium channel mutations– Chloride channel mutations

Page 9: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-4

• Which of the following abnormality is associated with ‘Juvenile Myoclonic Epilepsy’?– Sodium channel mutations– Calcium channel mutations– Potassium channel mutations– Chloride channel mutations

Page 10: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-5

• Which of the following abnormality is associated with ‘Temporal lobe epilepsy’?– Sodium channel mutations– Calcium channel mutations– Potassium channel mutations– Chloride channel mutations

Page 11: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-5

• Which of the following abnormality is associated with ‘Temporal lobe epilepsy’?– Sodium channel mutations– Calcium channel mutations– Potassium channel mutations– Chloride channel mutations

Page 12: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-6

• Pathophysiologically, which is the most important reason for the precipitation of seizure?– Increased Glutamate, increased GABA– Increased AMPA, increased GABA– Increased Glutamate, decreased GABA– Decreased Glutamate, increased GABA

Page 13: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-6

• Pathophysiologically, which is the most important reason for the precipitation of seizure?– Increased Glutamate, increased GABA– Increased AMPA, increased GABA– Increased Glutamate, decreased GABA– Decreased Glutamate, increased GABA

Page 14: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-7

• Clinically, the most relevant epilepsy classification system is:– ILAE 1985– ILAE 1989– ILAE 1991– ILAE 2006

Page 15: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-7

• Clinically, the most relevant epilepsy classification system is:– ILAE 1985– ILAE 1989– ILAE 1991– ILAE 2006

Page 16: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-8

• Which of the following is not a localization-related epilepsy?– Benign childhood epilepsy with centrotemporal

spikes– Juvenile myoclonic epilepsy– Childhood epilepsy with occipital paroxysms– Primary reading epilepsy

Page 17: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-8

• Which of the following is not a localization-related epilepsy?– Benign childhood epilepsy with centrotemporal

spikes– Juvenile myoclonic epilepsy– Childhood epilepsy with occipital paroxysms– Primary reading epilepsy

Page 18: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-9

• Which of the following is not an idiopathic generalized epilepsy?– Juvenile absence epilepsy– Epilepsy with grand mal seizures on awakening– Childhood absence epilepsy– Lennox-Gastaut syndrome

Page 19: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-9

• Which of the following is not an idiopathic generalized epilepsy?– Juvenile absence epilepsy– Epilepsy with grand mal seizures on awakening– Childhood absence epilepsy– Lennox-Gastaut syndrome

Page 20: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-10

• Which is the most important differential diagnosis of ‘first seizure’?– Migraine without aura– Abdominal migraine– Syncope– Migraine with aura

Page 21: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

MCQ-10

• Which is the most important differential diagnosis of ‘first seizure’?– Migraine without aura– Abdominal migraine– Syncope– Migraine with aura

Page 22: Dr. Hardeep Singh Malhotra  MD, DM, FIACM, MNAMS Associate Professor, Department of Neurology,

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