Dr-7000d Manual de Usuario

DR-7000D Semi-automatic Chemistry Analyzer DR-7000D Semi-automatic Chemistry Analyzer

Instruction:Thanks for purchase DR-7000D Semi-automatic Chemistry Analyzer.

In order to use the product correctly, please read the user manual carefully before operation.

Please keep the user manual safely for your anytime reference.

Caution:Colorimetric cuvette should be marinated by the alcohol at least 60 minutes after self-checking for the first time working, and then use distilled water to rinse it time by time for 10 minutes. If not, the test result might be inaccurate.

Content1Chapter 1 Introduction

11.1 About DR-7000D

11.2 Technical specification

21.3 Warning Mark

3Chapter 2 The Basic Principle and Functional Feature

32.1 Basic principle

42.2 Functions

5Chapter 3 Installation and Application

53.1 Instrument Installation

63.2 Main parts and Application

7Chapter 4 Basic Operation

74.1 Electrification

84.2 Sample testing

124.3 Program measurement

204.4 Quality control

224.5 Setup

244.6 Record search

254.7 Rinse

26Chapter 5 Instrument Maintenance

265.1 Instrument surface cleaning

265.2 Colorimetric cuvette cleaning

265.3 Lamp-house replacement

275.4 Fuse replacement

275.5 Pump pipette replacement

285.6 Print paper replacement

285.7 Printer crankshaft maintenance

29Chapter 6 Transportation and Storage

296.1 Transportation requirements

296.2 Storage requirements

30Appendix A

31Appendix B

33Appendix C

37Appendix D

39Appendix E

Chapter 1 Introduction

1.1 About DR-7000DDR-7000D was designed in response to the needs of clinical tests. It is a newly intelligentized filter chemistry analyzer.The built-in dot matrix LCD display provided with apheliotropic board ensures the clear show of all test results, functional status and operational instruction. The English indication system guides users operation, and improves man-machine communication. 1.2 Technical specification

a) Lamp-house: 20W /12v Halogen tungsten lampb) Wavelength: 340405450492505546578630 nm optionalc) ABS: -0.3~3.0 Absd) Wavelength accuracy: 1nm

e) Spectrum bandwidth6~12nmf ) Resolution: 0.1m Absg) Linearity2Abs2%1Abs0.5%

h) Stability 20 minutes for warm-up and then 2mAbs/h

i ) Blank: Auto zero upon the colorimetric cuvette with full of water

j ) Interface : RS-232 serial portparallel printer port k) Memory

Quality control data (valid period: 1 month) 200 testing programs, 3000 testing results

l) Test methods

End-point Kinetic

Two-point kinetic Absorbance Multipoint

m) Measurement time: 0~999 seconds programmable

n) Delay time: 0~999 seconds programmable

o) FlowcellQuartz flowcell, measuring volume is 32lp) Temperature control

Semiconductor device control , 253037 and room temperature optionalAccuracy 0.1

q) Sampling system

Peristaltic pump, controlled by step motorSampling volume: 100l~9999l programmable1l/step sampling volume programmable

r) Power supply: 100~240VAC 50/60Hzs) Environment condition:

Ambient Temperature15~30, optimal temperature: 15~25Relative Humidity85%RHt) Dimension462mm418mm232mm

u) Weight: 6.5kg1.3 Warning Mark

There are two biohazard marks on the equipment, one is Biohazard mark, another is Force electricity mark, they are all on the backboard of the equipment. As shown in Figure 1-1.

Warning mark

Figure 1-1 Warning Mark There might be a potential infectivity for the sample & waste reagent, please make sure to take protection action during the testing, cleaning process and instrument maintenance. Samples and waste reagent should be disposed in a suitable package conforming to the local regulation for laboratory.Chapter 2 The Basic Principle and Functional Feature

2.1 Basic principle

The principle of the instrument is based on the phenomenon of different wave band absorbance from substance, which is in line with Lambert-Bill Law.

A=log(I/I)=log(1/T)=bc T= I /IT Transparency c Solution layer thickness(cm)I Transmitted light intensity b Solution Moore concentration(mmol/ml)I Incident light intensity Solution Moore absorbance coefficient(mlmmol-1cm-1)A Absorbance2.1.1 Optical system

The prismatic part of DR-7000D Semi-automatic Chemistry analyzer adopts the filter in unique research and manufacture techniques. It is featured by moist-resistant, heat-resistant, longevity of service, little central wavelength excursion, high optical signal-noise ratio etc.. The principle diagram is shown as Figure 2-1.

Amplifier

Lamp-house Prismatic Flowcell Detector

System Figure 2-1 Principle diagram of optical system 2.1.2 Electronic system Flowcell Detector Amplifier Monochromator

Driver control Computer system Temperature control

VG

Lamp-house VI Display/Keyboard Printer

Vn

Figure 2-2 Electronic principle diagramThe principle diagram of the electronic system is shown above in Figure 2-2. When passing through the monochromator the ray of the lamp-house will be changed into monochromic light. The result will be then received by the photoelectric detector when it passes through the flow colorimetric cuvette, and further transformed into electric signal. The signal will be amplified and filtered, and then transmitted into A/D transformer. When the information is transformed into numbers, it will be sent into data collection system of the computer for kinds of calculation and transaction. Users can either read the final result on the display or alternatively get it printed out.2.2 Functions

1.Measurement methodsa) End-point b) Two-point kineticc) Kinetic d) Absorbancee) Multipoint2. Internal and external printer is available for uses options.

3. Sampling volume, test method is programmable.

4. Users can determine whether to execute real time print out of the test results.

5. If any operational mistakes or other false results are found during the process of measurement, users can choose the repeat key () to retest, the original serial number of the test remains.6. Rinsing program is available between two sample tests to avoid cross contamination.

7. Up to 1 month quality control tracking, and the printing results provided.

8. Integrated test report printing is available.9. Reaction curve display:Reaction curve for sample and standard liquid will be displayed on the screen during the testing, as shown in Figure 2-3. ABS LIMIT

Absorbance Absorbance ABS LIMIT 0 0

t1 time t1 time

(a)Positive reaction curve bNegative reaction curve

Figure 2-3 Activity reaction curveNote: 1. Press +/- to check the reaction curve after testing the standard liquid or sample.

2. Press Exit to test next sample.

Chapter 3 Installation and Application

3.1 Instrument Installation

3.1.1 Installation A. Move all the spare parts out after opening the package and then check the spare parts quantity according to the packing list, if there are some spare parts broken please contact the delivery forwarder or manufacturer.

B. Place the equipment on the selected work bench where is no vibration.

C. The equipment should not be placed close to the chemicals, caustic gas and electromagnet.

D. Prevent direct sunshine, humidity and high temperature.E. Operating temperature range is 1530 (optimal range: 1525), relativity humidity is less than 85%RH.F. The power supply of the instrument is 220V/50Hz and the plug is on the back-board, see Figure 3-1.

The instrument is provided with special two cores electric wire, which should be connected with well grounded receptacle after plugging in.

1. Power switch 2. Power socket 3. Fan 4. Fuse socket

5. Warning mark 6. Serial port 7. Parallel Port 8. Biohazard mark 9. Waste pipette Figure 3-1 Back-board outline3.1.2 Cautions for use Read the user manual carefully before working , especially for the caution & hazard info. Pre-heat for 20 minutes before working and use distilled water to wash the equipment before any test. Wash over 3~5 times immediately after each test. After finish working, wash time after time before turning off the instrument.

Make sure to maintain some cleaning agant in the colorimetric cuvette when it stops working to avoid the sample remain in the colorimetric cuvette.

The colorimetric cuvette should be washed and dipped everyday, firstly use cleaning agent or distilled water to wash it for several times, and then remain some cleaning agant in it.

When doing sample feeding operation, please pay attention to the sucking pipette and waste pipette, to avoid damaging and blocking.

Prevent vibration and direct sunshine and keep way from the wall at least 20cm.

3.2 Main parts and Application A. Display The display of DR-7000D Chemistry analyzer is dot-matrix large angle of view LCD, which adopts the latest STN technology. Its dimension is 108x58mm with dot-matrix 240x128. In addition, the apheliotropic board ensures clear reading in a poor light available.

BKeyboardThe keyboard comprises 19 key-presses, i.e. 12 number keys (including and radix point), 5 functional keys and EXIT and ENTER keys.

Number key Entering into submenu or numeric parameter input.

ENTER Press to confirm the executive command.

EXIT Press to return to the former menu.

F1 F5 (Functional key) Press to execute the relevant functions indicated in the five small squares at the bottom of the display.

C. Buzzer1. As the key-press on the control board is made of pellicle without clear tactility, buzzer reproducer is used to help inform operator as soon as the key-press is touched.

2. The buzzer will remind the user to move the sample away once the equipment finishes sampling.

D. Sample feeding switch and operationThe white sucking pipette is on the left of the instrument, and the switch of sample feeding is under it. Sample feeding operation: During the measurement, user can follow the instructions on the screen to do this operation, first put the sucking pipette into the bottom of prepared samples (including distilled water, reagent blank, standard liquid, sample blank, sample, quality-control sample), press the switch button and then the samples will be sucked automatically. Dont move the sample until 2-3 seconds later after the buzzer shows sample feeding is finished.

E. PrinterBoth of internal printer and external printer are available for the instrument. The user can select one of them for operation. There are 3 status optional: ON, OFF and AUTO. Real-time printing is available once select AUTO status.

Refer to 5.6 for the replacement of thermal sensitive print paper. Chapter 4 Basic Operation4.1 Electrification The power switch of the instrument is on the back-board (see Figure 3-1). Turn on the power switch to get the instrument in the state of electrification, and then the info in Figure 4-1-1 and 4-1-2 will be displayed on the screen orderly.

Figure 4-1-1

Figure 4-1-2Note: Under the Self checking interface(as shown in Figure 4-1-2), press the sucking button to enter into the submenu as shown in Figure 4-1-3.

Figure 4-1-3

Figure 4-1-4Reminder info (see Figure 4-1-5) will be shown on the screen after self checking. The user also could press Exit to omit it to enter into the test interface directly (To avoid inaccurate test result, please dont omit this process).

4-1-3Figure 4-1-5Key in the final selection and then enter into the program main menu, as shown in Figure 4-1-6.Note: If select Yes, all the test results will be deleted except for QC results and the sample serial number will be reordered from 1 automatically.If select No, the system will back to the main menu, as shown in Figure 4-1-61. Sample testing 2. Parameter setup3. Quality control4. Setup

5 .Record search

6. RinseFigure 4-1-6There are 6 submenus under the main menuPress 1 to enter Sample testing mode to do normal testPress 2 to enter Parameter setup mode to edit and modify relevant test parameters.

Press 3 to enter Quality control mode to edit the control parameters or look over control statistics.Press 4 to enter Setup mode to setup the language, printer status, time, date, ID and lamp-house luminosity.Press 5 to enter Record search mode for the search of relevant record.Press 6 to do the rinsing operation.4.2 Sample testing Under the main menu, press 1 to enter item display submenu. As shown in Figure 4-2-1. There are 10 sorts for the test items: LIVER, KIDNEY, CARDIAC ENZYME, BLOOD, BLOOD LIPID, HYDRONIUMGROUP 1, GROUP 2, GROUP 3, GROUP 4; There are 20 items under each sort and 200 items totally. Funtion key F4 and F5 are used for page up and page down.

The skip point at the first item after enter into the test item interface, there are 2 ways to select the item.Way 1: Input the item number (such as 001).Way 2: Press the funtion key F1 and F2.

Figure 4-2-1NoteIf inaccurate item number is input, it will be corrected by key the accurate one under the same interface directly and the original one will be covered automatically, the item no. should be 3 digits.

Input the selected Item Number. (such as: 003 or press F2 to select 003) and then press Enter to enter into the test status. As shown in Figure 4-2-2.

Rinse Print Calibrate Zero QC Figure 4-2-2Press the sucking button to suck the distilled water and then the following info (as shown in Figure 4-2-3) will be shown on the screen. Please follow the screen reminder info to do the test operation one by one.

Rinse Print Calibrate Zero QC

Figure 4-2-3Note:

a) Press sucking button to make the distilled water, reagent, sample, standard liquid and quality control liquid are all sucked into the colorimetric pool by sucking pipette according to the reminder info one by one, and then test results and ABS value will be shown on the screen after finishing measurement. If printer status is ON, press F2 to print the test results out and press 8 to run the print paper; If printer status is AUTO, the printer will execute real time test result print-out. Test results will be saved automatically, if the test results exceed 3000 pieces, the reminder info THERE IS NO SPACE FOR DATA BASE, CLEAR ALL SAMPLE DATA?, press EXIT to out and press ENTER to clear it. The equipment will not be workable unless do the clear operation.b) One sample serial number is only correspond with one patient, it will be added 1 after each testing automatically. Further more the operator also could press ENTER button to enter into sample edit submenu, as shown in Figure 4-2-4, and then input a new sample serial number. (within 001-999).

Figure 4-2-4Press ENTER after inputing the sample number and it will be the serial number for the next testing sample.

c) If ID STATUS is ON, there are 2 ways to input the ID number, one is by barcode reader, another is by press number 9 button to enter into the ID edit interface (as shown in figure 4-2-5), and then input the ID number (0~9) by hand (the ID number should not more than 10 digits), otherwise, there will be no ID number.

Note:(1) There is only one ID correspond with one daily sample number. One time ID number input is avaiable for the samples which use the same sample serial number.(2) There is no ID for new sample, repeat ID input is avaiable and the system will keep the final one as the ID number.d) Repeat test could be done after pressing the repeat key and the original sample no. will not be changed.

e) If quality control or re-calibration is required, press F5 or F3 and then Pump standard liquid again? or Pump control liquid again? info will be shown on the screen fFor the end point measurement, reminder info Test the reagent blank again ? will be shown on the screen after setting parameters again, user could select the proper info, if select 1 the reagent blank value will be tested again or it will be calculated according to the original value by the equipment. As shown in Figure 4-2-6.

Enter into standard liquid test interface after finishing reagent blank test and the reminder info Test standard liquid again? will be displayed on the screen, as shown in Figure 4-2-7.

g) For the END point, two poin and Kinetic measurement, if the test time is not 0, the reaction curve will be displayed on the screen in real time. After displaying the test results, press button the enlarge reaction curve will be displayed on the screen.4.3 Program measurement Under the main menu (as shown in Figure 4-1-6), press 2 to enter test program submenu, as shown in Figure 4-3-1.

Figure 4-3-14.3.1 Parameter setupFor example, input 003 or press F2 () 2 times to select item TP and then press Enter to enter into its submenu. As shown in Figure 4-3-2.

Figure 4-3-2The content in the bracket is the item instruction of program (Reminder info.) P1, P2, P3 P4 on the top of the screen means the page number, Press F4, F5 to do page up and page down operation, press 1-6 to edit and modify the content of relevant items.There are totally 5 pages of program submenus, P1 in Figure 4-3-2 means Page 1, press F5 to view Page 2 (see Figure 4-3-3), Page 3 (See Figure 4-3-4) and Page 4 (See Figure 4-3-5). Figure 4-3-3

Figure 4-3-4If select the Multipoint method, concentration parameter under P4 should be input, however, it is no need for other measurement methods.

Figure 4-3-54.3.2 Parameters modificationA) Modifying test nameUnder the program submenu ( as shown in Figure 4-3-2), press 1 and then press ENTER to enter into Program submenu, as shown in Figure 4-3-6:

Figure 4-3-6As known from above, corresponds to F1, corresponds to F3, Delete corresponds to F4, PA( Page down) corresponds to F5.

For example, to change the name into GPT: Press F3 (or F1) to move the cursor to the line where there is G, then press 6 (G is correspond to 6), G will be displayed in the Name Column. Press F3 (or F1) to move the cursor to the line where there is P, then press 5 (P is correspond to 5) GP will be displayed in the Name Column, and so forth. When all finished, press ENTER to return to the last submenu (if the input is more than 8 letters, it will return to last submenu automatically). If any letter is entered incorrectly, press F4 to delete the letter. For lowercase entering, press F5 to look up lowercase on the next page.

BModifying Temperature Press 2 under the submenu on the first page (as shown in Figure 4-3-2), then press ENTER, the screen is shown as Figure 4-3-7

Key in the number in front of the selected temperature, then press ENTER to return to the submenu.

CModifying measure methodPress 3 under the submenu on the first page, then press ENTER, the screen is shown as Figure 4-3-8.

Figure 4-3-8Select the proper number and then press ENTER to back the upper menu.

DModifying unitsPress 4 under the submenu on the first page, then press ENTER. As shown in Figure 4-3-9

F5 is for page down ,as shown in Figure 4-3-10

Figure 4-3-10Key in the number in front of the selected unit, then press ENTER to return to the submenu (as shown in Figure 4-3-2).

E) Modifying linearity range: Press 5 under the submenu on page 1, then press Enter As shown in Figure 4-3-114-3-12

Figure 4-3-11

Figure 4-3-12Input the proper parameter and then press Enter to back to the submenu (as shown in Figure 4-3-2).

Note:Input the linearity range according to the specification on the reagent kits, if the parameters exceed the range during test, reminder mark ! will be printed on the test report.! means Test the sample again after dilution and the result should be multiplied the dilution multiple.FModifying Reagent BlankPress 1 under the program menu on the second page as shown in Figure 4-3-3 , then press ENTER, as shown in 4-3-13

Figure 4-3-13Press 0 or 1 for R-blank Yes or No, then press ENTER to return to the submenu ( as shown in Figure 4-3-3).GModifying sample blank Press 2 under the program menu on the second page (as shown in Figure 4-3-3), then press ENTER, as shown in Figure 4-3-14:

Figure 4-3-14HModifying standard liquid concentration: Press 3 under the submenu on the second page (as shown in Figure 4-3-3), then press ENTER, as shown in Figure 4-3-15

Figure 4-3-15Input the proper standards liquid concentration, then press Enter to back to the submenu.

Note: The factor will be turned into ---- automatically after entering the standard liquid concentration.The factor will be saved automatically and reminder info Confirm the standard liquid again? will be shown on the screen once the user opens the submenu again, if select yes, the old coefficient will be replaced by the new one.I) Modifying FactorPress 4 under the program menu on page 2 (as shown in Figure 4-3-3), then press Enter. The factor is 00000. input proper value, then press Enter to return to the submenu. As shown in Figure 4-3-16.

Figure 4-3-16NoteThe standard concentration will turn into ----- after entering the factor value automatically.JModifying the sampling volumePress 5 under the program menu on Page2 (as shown in Figure 4-3-3), then press ENTER. Input the proper number, then press ENTER to return to the submenu. As shown in Figure 4-3-17.

Figure 4-3-17Note: the min. sample volume is 100l, however, in order to reduce the cross-contamination of samples with high concentration, it is better to adjust it to 500l at least.KModifying the decimal digits of test results: Press 6 under the program menu on page 2 (as shown in Figure 4-3-3), then press Enter to input the required decimal digits, then press Enter to turn to the submenu. As shown in figure 4-3-18. (Decimal digits is the numbers after the radix point of the test result, the max. one is 4 digits such as 1.2334).

Figure 4-3-18L) Modifying wavelengthPress 1 under the program menu on Page 3 (as shown in Figure 4-3-4), then press ENTER. Input the selected wavelength number, if correct, press ENTER to back to the submenu (sub. wavelength press 2), as shown in Figure 4-3-19.

Figure 4-3-19Note: There will be a reminder info Input wavelength again on the screen, once main wavelength value input is unavailable and the operator should input the wavelength again. M) Modifying delay timePress 3 under the main menu on page 3 (as shown in Figure 4-3-4), then press ENTER. Input the proper time, if correct, press ENTER to back to submenu. (Delay time setup should be according to the specification on the reagent kits), as shown in Figure 4-3-20.

N) Modifying test time Press 4 under the main program menu on page 3 (as shown in figure 4-3-4), then press ENTER, input proper number, if it is correct, press ENTER to back to the submenu. As shown in Figure 4-3-21.

Note: Measure time is only applied when using two-point kinetic and kinetic mode.

O) Modifying reference highUnder the main program press 6 on page 3 (as shown in figure 4-3-4), then press ENTER. Input the proper number , if it is correct, press ENTER to back to the submenuas shown in Figure 4-3-22.

Figure 4-3-22P) Modifying reference lowUnder the main program press 5 on page 3 (as shown in figure 4-3-4, then press ENTER. Input the proper number , if it is correct, press ENTER to back to the submenuas shown in Figure 4-3-23

Figure 4-3-23Note: All parameters above should be selected according to the specification on the reagent kit. (If test result is not within the ref value range, & reminder info will be marked behind the result.) 4.4 Quality control Under the program main menu (as shown in figure 4-1-6), press 3 to enter into the Quality Control submenu , as shown in Figure 4-4-1:

Figure 4-4-14.4.1 Program quality control

Press 1 under the quality control submenu, then press ENTER to enter into the submenu, as shown in Figure 4-4-2:

1-1

Figure 4-4-2Input the selected Item number then press ENTER to enter into the submenu, as shown in Figure 4-4-3, then input the proper number, if it is correct, press ENTER, as shown in Figure 4-4-3.

Input the proper number of control lot, target value and standard deviation one by one. If they are correct, press ENTER to back to main menu. Two types of control liquid are available for the program. 4.4.2 Modifying control statistics Under the program main menu, press 2 to enter into the Control Statistic submenu, as shown in Figure 4-4-4.

Press 1 ----- Present control data will be shown on the screen.

Press 2 -----Individual control data will be shown on the screen.Press F2 or to select the edited QC item and then press ENTER to enter into the submenu, as shown in Figure 4-4-5.

Press or to view the control data within 1 month. 4.4.3 Statistic data clearance Press 3 under the program main menu (as shown in Figure 4-4-1), then press ENTER to enter into the submenu, as shown in Figure 4-4-6:

Figure 4-4-64.4.3.1 All control data clearance

Press 1 under the main menue (as shown in Figure 4-4-6) to enter into the submenu, as shown in Figure 4-4-7.

Figure 4-4-7Press ENTER to clear all the statistic data and then back to upper menu, as shown in Figure 4-4-6.4.4.3.2 Individual control data clearance

Press 2 under the main menue (as shown in Figure 4-4-6) to enter into the individual control data submenu as shown in Figure 4-4-8.

Figure 4-4-8Press Enter to enter into the submenu, key in the selected number and then press ENTER to clear it.4.5 Setup

Under the program main menu, press 4 to enter into the submenu, as shown in Figure 4-5-1.

4.5.1 PrinterUnder the setup menu (as shown in figure 4-5-1), press 2 to enter into the printer submenu, as shown in Figure 4-5-2:

Press 1 to select the status of internal printer, then press ENTER to back to the submenu.

Press 2 to select the status of external printer, then press ENTER to back to the submenu.Press 3 to select the run paper distance (per time) and the printed test result line-distance, there are 5 values optional: 2, 4, 6, 8, 10 line.4.5.2 Date & TimePress 3 under the setup menu (as shown in Figure 4-5-1) and then press ENTER to enter into the submenu as shown in Figure 4-5-3:

Input the proper number, then press ENTER to back to the submenu.4.5.3 Lamp- house replacement Press 4 under the setup menu (as shown in Figure 4-5-1) to enter into the lamp-house submenu, as shown in Figure 4-5-4:

Program indicates pump, and set wavelength 340nm automatically, then read the number of the luminosity continually. Press EXIT to back to last menu.

4.5.4 ID setup Press 5 under the Setup menu (As shown in Figure 4-5-1) to set up the ID and then press ENTER TO back the upper menu.

4.6 Record search

Under the program main menu (as shown in Figure 4-1-6), press 5 to enter into the record search submenu, as shown in Figure 4-6-1:

Figure 4-6-14.6.1 Record search

Under the RECORD SEARCH submenu( as shown in Figure 4-6-1), search function is avaiable once press any key within 1 to 4, such as press 1 ,the following interface will be shown on the screen.

Single Print Del Prior Next

Figure 4-6-2Press F1 to select the printing report format (single or integrate).Press F2 to print the test report.Press F3 to delete the current note.Press F4 to display the previous record.Press F5 to display the next record.Press EXIT to back to the upper menu (as shown in Figure 4-6-1).4.6.2 Record clearanceUnder the record clearance menu (see Figure 4-6-1), press 5 to enter into the record clearance submenu, as shown in Figure 4-6-3:

Figure 4-5-6Figure 4-6-3Press 1 to clear all the records and press EXIT to back to upper menu as shown in figure 4-6-1.4.7 Rinse

Under the program main menu (as shown in Figure4-1-6), press 6 to enter into RINSE submenu, as shown in Figure 4-7-1.

Figure 4-7-1Input the rinse time by hand and then press ENTER. The equiment will do the rinse operation according to the selected time automatically. (Rinse time scope 1~99)Chapter 5 Instrument Maintenance5.1 Instrument surface cleaningUse the wet cloth and cleaning agent to clean the instrument. To avoid damage the DOS shell and the liquid flow into the equipment, prohibit using any corrosive impregnants.5.2 Colorimetric cuvette cleaning(1) The colorimetric cuvette should be washed by the cleaning agent or distilled water between each test.(2) After finish working everyday, wash several times by the cleaning agent to rinse the remains in the colorimetric cuvette.

(3) To avoid serious contamination, adjust the temperature to 37 to accelerate the cleaning speed, first in cleaning agent, then in distilled water to wash it several times.

(4) Make sure to maintain some distilled water in the colorimetric cuvette when the equipment stops working everyday. 5.3 Lamp-house replacement (1) Turn off power firstly when replacing Lamp-house.

(2) Push the sucking pipette out of the instrument smoothly, and then take down the screw from the bottom of the instrument. Lift the DOS shell smoothly from the back shell (do not take it off rapidly), leaving the front on the table. Pull out the sucking pipette from inside completely before DOS shell is lifted up.

(3) Take off the lampshade and pressure pad firstand then take down the illuminant. (Warning: light bulb and ambient temperature may be very high, to avoid dangers, please take gloves to do this operation).

(4) Insert the new bulb (12V, 20W) in the lamp stand without touching the top of the light bulb, and then screw the pressure pad. To avoid effecting the test results, please do not touch the bulb by hand directly. Use alcohol cotton to clean it. (5) Under such circumstance, switch on the power to enter into setup menu ,then press 4 to enter into the lamp house replacement submenu, according to the reminder info to pump the distilled water and then the Luminosity value will be shown on the screen.

(6) Adjust the position of lamp-house until the figure on the bottom of the display turned into maximum (Reference range 18000~50000).

(7) Ensure the figure on the bottom of the display unchanged, and tighten all screws.

(8) Turn off the power, and put on the lampshade. Thus the illuminant replacement is finished.

(9) Insert the pipette properly. Put DOS shell on and tighten all screws.

Figure 5-3-1

5.4 Fuse replacement The fuse socket is on the back board of the instrument, below the power switch and on the top of the entrance of electric wire. As shown in Figure 5-4-1. Pull out the electric wire, pick off the fuse socket to replace the fuse offered by manufacturer.

Fuse socket Fuse Figure 5-4-15.5 Pump pipette replacement Open the DOS shell, the method is same to the lamp-house replacement (see step1&2). Press the stay bar to open the block board under the pump, move the pump pipette out and then replace a new one.

To avoid leaking, tighten the screw to tense the pipette properly.

Pump pipette:

Diameter 2.06mminner

Length90mm

Stay bar Block board pump bearingFigure 5-5-1

5.6 Print paper replacement SPRM printer is provided with paper scroll before leaving factory, but it is not been inserted. This is for the safety of the printer during the extended transportation and storage. Insert the paper scroll before use, refer to the following steps:

(1) Press the cover below the paper exit gently, the cover will flick automatically and be open.(2) Cut the paper as Figure 5-6-1.

(3) Switch on the printer power, insert the paper into the paper entrance, it will enter into the crankshaft automatically.

Paper Entry

Stay bar

5.7 Printer crankshaft maintenanceIn order to ensure the normal work of the printer, please do not take the crankshaft down discretionarily.

(1) When replacing the paper, check whether any wastepaper maintains on the crankshaft, blow off it if there is any. (2) Ensure the clean of external board.(3) When thermal sensitive printer is dirty (print results is not clear), clean it with alcohol cotton.(4) Do not pull the paper emphatically before the crankshaft is put up.Chapter 6 Transportation and Storage

6.1 Transportation requirements 1. Anti-moisture and anti-water works should be done well before transportation.

2. Avoid strong shake and extrusion.3. Take care to move, pack or unpack the instrument.

6.2 Storage requirements1. Indoor

2. Temperature: -40~ +50 3. In a well-ventilated, clean and dry area, away from chemicals and caustic gas.Cautions:The instrument should be rinsed several times and the sucking pipette should be kept empty & dry before transportation or storage. If the transportation ambient temperature is lower than 0, it is better to use 95% alcohol to rinse the pipette in order to avoid frost crack. Appendix A Manufacturers warrantyDear CustomerThanks for purchasing DR-7000D semi-automatic chemistry analyzer, our company will provide the following services for you: 1. Technical consultations are provided at any time. 2. Maintenance free of charge within one year from the day you purchase the instrument. 3. Maintenance will be charged in the following conditions.(1) Product which has expired the warrantee date.

(2) Damage caused by accidental factors or improper use.

(3) Damage caused by the operation that is not according to the user manual.

(4) Damage caused by your own repair without our companys permission. 4. We will provide updated service for free according to the technology improvement.Any technological service requests, please contact us according to the following address:

DIRUI INDUSTRIAL CO., LTD.95 Yunhe street, New & High Tech. Development Zone

Changchun, JiLin 130012 P.R. China

Tel: 86-431-85100409

Fax: 86-431-85172581E-mail:[email protected]

http://www.dirui.com.cn

Appendix B Trouble shootingFaultReasonTrouble shooting

1. The fan and W lamp do not work after switching on the power.The fuse is broken.Replace the fuse (2A).

2. After switching on the power, the fan works but W lamp doesnt work.W lamp is broken or without voltage.

First check whether the voltage for lamp house is 11.0V. If the voltage is as normal, then W lamp is broken, replace a new one.

3. Tested result is not good.Sample feeding generates air bubble, pump delivery and speed is instable.After several rinsing or sample feeding, if it still doesnt work properly, wash it with specific cleaning agent for 2-3 times, then with distilled water for 5-10 times. Re-input the pump parameters.

4. The printer doesnt work and display E1, E2, E3, E4 etc info.Printer plug falls out or is loose connection.Open the DOS shell, reinsert plug and check if the light for printer board flashes.

5. The pump does not run after switching on the sample feeding power.Switch damaged or loose connection.Open the DOS shell, reinsert plug or replace the switch.

6. Sampling abnormity after system self-checking.Interface from the outside electric net.Turn off the power and restart the equipment after several seconds.

7. Temperature abnormity

after system self-checking.Temperature sensor socket is not connected well or the temperature exceed the scope of 5~40.Turn off the power in normal room temperature, restart it after 5 minutes.If it is not workable, open the equipments shell and refix the sensor socket.

8. The buzzer doesnt work.Computer shuts down, which is usually caused by external interference.Turn off the power, and restart a few seconds later.

9. some a key does not work.Key cover is used too much.Replace the key cover.

10. Display with variegation after switching on.It is usually caused by external interference.Turn off the power, and restart a few seconds later. Or open case, reinsert all cables connection.

11. The pump works without sample feeding.

Flow system is blocked or pipette aging or Blocked.Check that if the input and output pipette are twisted or extruded, and check if pump pipette is tightened or aging. To replace with a new one or cut it shorter. And clean and impregnate flowcell.

12. Instrumet alarm.Re-operate based on manual. If it happens often, please contact the supplier.

Appendix C Communication Interface with ComputerBaud rate:9600

Data bit: 8 bitsStop bit: 1 bit

Verification: none

Hardware hold hands: noneStart character: 02H

2 bytes space: 20H

Line feed character:0DH0AH

Ending character: 03H

Connection between chemistry analyzer and computer

Test report data output format

1 Data output formatindividual data

123456789101112131415161718192021222324252627282930

STXCRLF

SPSPSPTestingSPReportCRLF

CRLF

SPDate:--SP::CRLF

SPSampleSPNO.:CRLF

SPID:CRLF

SPTestSPName:CRLF

SPREF:SPCRLF

SPSeq.SPSPResultSPSPUnitSPSPHintCRLF

SPSPSPSPCRLF

CRLF

ETX

Note

SP------- space character (20h hex)

X--------- virtual value bitSTX----- start character (02h hex)

CR------- return character (0dh hex)

LF-------- line feed character (0ah hex)

ETX------ ending character (03h hex)2 Data input formatIntegrated data123456789101112131415161718192021222324252627282930

STXCRLF

SPSPQualitySPControlSPReportCRLF

CRLF

SPDate:--SP:CRLF

SPTestSPName:CRLF

SPID:CRLF

SPStandardSPX:SPCRLF

SPStandardSPSD:SPCRLF

SPResult:CRLF

ETX

3Data output formatQC data 123456789101112131415161718192021222324252627282930

STXCRLF

SPSPQualitySPControlSPReportCRLF

CRLF

SPDate:--SP:CRLF

SPTestSPName:CRLF

SPID:CRLF

SPStandardSPX:SPCRLF

SPStandardSPSD:SPCRLF

SPResult:CRLF

ETX

Appendix D Regular Chemistry Reagent ListParameterCode No.ProductMethodologyWavelengthTemperatureStandard

concentrationFactorUnitMeasurement time(S)Lag time

(S)Reagent

Liver

Function01ALTKinetic340nm37-3376U/L6060double reagent

02GGTKinetic405nm371158U/L6060double reagent

03ALPKinetic405 nm373378U/L6060double reagent

04CHEKinetic405 nm378369U/L6060double reagent

05T-BILEnd point546 nm3789.6umol/Ldouble reagent

06D-BILEnd point546 nm3726umol/Ldouble reagent

07ALBEnd pint630 nm3740g/Lsimple reagent

08TPEnd pint546 nm3780g/Lsimple reagent

09NH32-point kinetic340 nm37200umol/Lsimple reagent

10ASTKinetic340 nm37-3376U/L6060double reagent

11LAPKinetic405 nm372121U/L6060double reagent

12ICDHKinetic340 nm373376U/L60120double reagent

13ADAKinetic340 nm374921U/L60180double reagent

Kidney

Function14BUN2-point kinetic340 nm377.14mmol/L6030double reagent

15Cr2-point kinetic505 nm37400umol/L6030double reagent

16UAEnd point505 nmroom temperature7.2mmol/Ldouble reagent

Hydronium17CaEnd pint578 nmroom temperature2.5mmol/Ldouble reagent

18CaEnd pint630 nmroom temperature2.5mmol/Lsimple reagent

19CIEnd point505 nmroom temperature100mmol/Lsimple reagent

20MgEnd point546 nmroom temperature1mmol/Lsimple reagent

21FeEnd point546 nmroom temperature90umol/Ldouble reagent

22PEnd point340 nmroom temperature1.29mmol/Lsimple reagent

Glucose

metabolism23GLUEnd point505 nm375.55mmol/Ldouble reagent

24GLUEnd point340 nm375.55mmol/Ldouble reagent

Code No.ProductMethodologyWavelengthTemperatureStandard

concentrationFactorUnitMeasurement time(S)Lag time

(S)Reagent

25FTSEnd point546 nm371.95mmol/Lsimple reagent

Blood

lipoid26CHOEnd point505 nm377.0mmol/Ldouble reagent

27HDL-CEnd point546 nm3753mmol/Ldouble reagent

28LDL-CEnd point546 nm3777mmol/Ldouble reagent

29TGEnd point546 nm372.2mmol/Ldouble reagent

30LDH-LKinetic340 nm379683U/L6060double reagent

31CKKinetic340 nm378095U/L60120double reagent

32CK-MBKinetic340 nm378254U/L60120double reagent

33HBDHKinetic340 nm374920U/L6060double reagent

Acute

abdomen34AMYKinetic405 nm375138U/L6060double reagent

35AMYKinetic405 nm375138U/L6060double reagent

Note:

1. The above info just for regular items, for the details, please check the specification on the reagent kits.

2. User also could program the new parameters according to the specification on the reagent kits.

Appendix E Bar code reader installation and operation

1. Installation

The bar code reader is the optional spare parts for DR-7000 series semi-automatic chemistry analyzer, there is a serial port on analyzer back board for it installation. The operation is very easy, operator only need to insert the bar code reader connector plug into the proper serial port.

Notice: The equipment should be powered off before bar code reader installation.

2. Operation

(1) The bar code reader could read Code-39, Code-128, EAN-8, UPC-E and Inter leaved 2 of 5 bar code automatically and the total digit for the bar code number should not more than 10 letters, otherwise, it will not workable.

(2) The operator could do the scan operation before each test (ID should be setup ON) and then the bar code number will be saved into ID number. There is only one bar code number for each sample, therefore, it is only need to scan one time for the same sample or the equipment will save the last scan one as the final one.

(3)The bar code reader belongs to far-distance Reader, the operator only need to aim the scan point at the barcode number and then press the trigger, so that, the real-time bar code info will be shown on the screen.

(4)The bar code reader reads the barcode by the light line center on the top of it, to avoid mistakes, the light line should cover the whole barcode and keep proper bevel with the trigger before reading.

Connection of stylus printer

Instrument could connect EPSON LQ300K+ stylus printer. (Other type stylus printer can be used as well, but it may cause some change in print speed and character position.)Rev: 06/2009Warning mark

Biohazard mark

Biohazard mark

A/D

Semi-Automatic

Chemistry Analyzer

Version x.x x

Feb 6 2007

050715

191311

Self checking

Please pump distilled water

050715

191320

Self checking

Please waiting

050715

191351

warm-up for 20 minutes should be done before testing

if not, test results might be inaccurate !!

Clear all sample data?

Yes- press Enter

No- press Exit

001)ALT

002) ALP

003) T-BIL

004)ALB

005)BUN

006) Cr

007) CO2

008) CL

009) Fe

010) GLU

LIVER :

Pre. Next 002 Up Down

011)r-GT

012)CHE

013)D-BIL

014)TP

015)BUN

016)AST

017)Ca

018)P

019)Mg

020)CHO

Test nameALT 050716

ModeKINETIC

Sample No.001

Medium: Sample

ABS

Factor-3376

Result

Please Pump distilled water

Test nameTP 050716

Mode ENDPOINT

Sample No.001 ID:

Medium: sample

ABS

Factor

Result

Please pump sample

__ __ __ __

Input sample No.

__ __ __ __ __ __ __

Input ID No.

Figure 4-2-5

Test nameTP 050716

Mode ENDPOINT

Sample No. ID:

Medium:

ABS0.02

Factor 1-YES

Result 2-NO

Test reagent blank again?

Rinse Print Calibrate Zero QC

Figure 4-2-6

Test nameTP 050716

ModeENDPOINT

Sample No.

Medium

ABS0.002

Factor 1-YES

Result 2-NO

Test standard liquid again?

Figure 4-2-7

Rinse Print Calibrate Zero QC

001)ALT

002) AST

003) TP

004)ALB

005)T-BIL

006) D-BIL

007) TBA

008) ALP

009) GGT

010) LAP

LIVER

Pre Next 001 Up Down

011)AMM

012)CHE

013)GLDH

014)ICDH

015)

016)

017)

018)

019)

020)

1TEST NAME TP

2TEMP -- --

3MODE END POINT

4UNITS g/L

5LLOW:0.0000

6LHIGH:150

UP DOWN

Program P1

1R-BLANK NO

2S-BLANK NO

3STANDARD0.0

4FACTOR 0.1

5VOLUME 500

6. FLOAT: 002

UP DOWN

Program P2

1WL1 000

2WL2 --------

3DelayS: 000

4MEASS: 000

5REF-LOW: 0.1

6REF-HIGH: 0.1

UP DOWN

Program P3

STANDARD1: 0.000

STANDARD2: 0.000

STANDARD3: 0.000

STANDARD4: 0.000

STANDARD5: 0.000

Program P4

P3

UP DOWN

1Test name

0 1 2 3 4 5 6 7 8 9

0 1 2 3 4 5 6 7 8 9

A B C D E F G H I J

K L M N O P Q R S T

U V W X Y Z

Del Page

Program Test name

2TEMP

0

125

230

337

ProgramTemperature

Figure 4-3-7

3MODE

0 ENDPOINT

1 TWOPOINT

2 KINETIC

3 MULTI-POINT

4 ABS

ProgramTest mode

4UNITS

0ABS

1U/L

2kat/L

3mmol/L

ProgramUnits

Page

4.mol/L

5.g/L

6.g/dL

7. mg/dL

Figure 4-3-9

4UNITS

0g/dL

1U/mL

2nmol/L

3mg/L

ProgramUnits

Page

4.g/L

5.ng/L

6.

Input L-LOW value:

Input L-HIGH value:

1.R-BLANK

0 NO

1 YES

ProgramReagent Blank

2.S-BLANK

0 NO

1 YES

ProgramSample blank

Input standard liquid

Input factor

uL

Input sample volume

Decimal digi

Input float 0-4

__

WAVE

1340 5505

2405 6546

3450 7578

4492 8630

n m

Input wavelength 1:

___ ___ ___ S

Input delay time

Figure 4-3-20

___ ___ ___ S

Input measuring time

Figure 4-3-21

________________________

Input REF-High

__________________________

Input REF-Low

Input No.

1Program