DOXYCYCLINE TO TREAT LEVODOPA-INDUCED DYSKINESIAS IN PARKINSON’S DISEASE: A PROOF-OF-CONCEPT STUDY Bruno Lopes Santos-Lobato 1,2 *, Manuelina Mariana Capellari Macruz Brito 1 *, Ângela Vieira Pimentel 1 , Rômulo Torres Oliveira Cavalcanti 1 , Elaine Del-Bel 3 , Vitor Tumas 1 1 Department of Neuroscience and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil 2 Laboratory of Experimental Neuropathology, Federal University of Pará, Belém, Brazil. 3 Department of Basic and Oral Biology, Faculty of Odontology of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil * Authors contributed equally to this work + Corresponding Author: Dr. Vitor Tumas Departamento de Neurociências e Ciências do Comportamento Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo Av. Bandeirantes 3900, CEP: 14049-900 - Ribeirão Preto, São Paulo, Brazil Phone: + 55 16 3602-2557 E-mail: [email protected] ORCID ID of authors of the manuscript: . CC-BY-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. (which was not certified by peer review) The copyright holder for this preprint this version posted May 19, 2022. ; https://doi.org/10.1101/2022.05.13.22275023 doi: medRxiv preprint NOTE: This preprint reports new research that has not been certified by peer review and should not be used to guide clinical practice.
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