doc.: IEEE 802.15-12-0394-00-004n Submission July 2012 Project: IEEE P802.15 Working Group for Wireless Personal Area Project: IEEE P802.15 Working Group for Wireless Personal Area Networks (WPANs) Networks (WPANs) Submission Title: Overview of I2R’s Wireless Transceiver Design for MBAN Activities Date Submitted: July 17, 2012 Source: Dr. Sumei Sun Contact: Dr. Sumei Sun, Institute for Infocomm Research (I2R), ([email protected] ), Dr. Xiaoming Peng ([email protected] ) Re: Overview of I2R’s Wireless Transceiver Design for MBAN Activities Abstract: Purpose: To focus activities during the meeting Notice: This document has been prepared to assist the IEEE P802.15. It is offered as a basis for discussion and is not binding on the contributing individual(s) or organization(s). The material in this document is subject to change in form and content after further study. The contributor(s) reserve(s) the right to add, Slide 1 Sumei Sun, I2R
Doc.: IEEE 802.15-12-0394-00-004n Submission July 2012 Project: IEEE P802.15 Working Group for Wireless Personal Area Networks (WPANs) Submission Title:
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doc.: IEEE 802.15-12-0394-00-004n
Submission
July 2012
Project: IEEE P802.15 Working Group for Wireless Personal Area Networks (WPANs)Project: IEEE P802.15 Working Group for Wireless Personal Area Networks (WPANs)
Submission Title: Overview of I2R’s Wireless Transceiver Design for MBAN Activities
Date Submitted: July 17, 2012Source: Dr. Sumei SunContact: Dr. Sumei Sun, Institute for Infocomm Research (I2R), (
[email protected]), Dr. Xiaoming Peng ([email protected])
Re: Overview of I2R’s Wireless Transceiver Design for MBAN ActivitiesAbstract:Purpose: To focus activities during the meetingNotice: This document has been prepared to assist the IEEE P802.15. It is
offered as a basis for discussion and is not binding on the contributing individual(s) or organization(s). The material in this document is subject to change in form and content after further study. The contributor(s) reserve(s) the right to add, amend or withdraw material contained herein.
Release: The contributor acknowledges and accepts that this contribution becomes the property of IEEE and may be made publicly available by P802.15.
Slide 1 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
July 2012
Slide 2 Sumei Sun, I2R
Outline
• Background
• Wireless Transceiver design for In-body Diagnosis
• Wireless Transceiver for Implantable Device for Treatment
doc.: IEEE 802.15-12-0394-00-004n
Submission
July 2012
Slide 3 Sumei Sun, I2R
• Background
• Wireless Transceiver design for In-body Diagnosis
• Wireless Transceiver for Implantable Device for Treatment
doc.: IEEE 802.15-12-0394-00-004n
Submission
Singapore Institute of Manufacturing Technology (SIMTech)
Institute of High Performance Computing (IHPC) Institute of
Materials Research & Engineering (IMRE)
Institute of Microelectronics (IME)
Institute for Chemical & Engineering Sciences(ICES)
Data Storage Institute (DSI)
The A*STAR FamilyThe A*STAR Family
July 2012
Slide 4 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission Slide 5 Sumei Sun, I2R
A*STAR’s BEP Program • The Biomedical Engineering Programm (BEP) is a competitive,
multi-disciplinary grant programm• Aiming at engaging the local clinical community with engineers and
scientists to develop cost-effective innovations through a needs-driven approach that will improve patient care
• Funded by the Science and Engineering Research Council (SERC) of A*STAR
• Supports Clinician-Engineer/Scientist collaborative research projects with emphasis on devices, procedures, diagnosis, and clinical systems
• The two use cases we share in this presentation are supported under the Program.
July 2012
doc.: IEEE 802.15-12-0394-00-004n
Submission
Outline
• Background
• Wireless Transceiver design for In-body Diagnosis
• Wireless Transceiver for Implantable Device for
Treatment
doc.: IEEE 802.15-12-0394-00-004n
Submission
Introduction• Capsule endoscopy is a technique
which facilitates imaging of the gastro-intestinal track
• Can be used to evaluate cause of gastro-intestinal bleeding and the surveillance of small bowel tumor and polyps
• Safe and well-tolerated procedure, with low complication rates
July 2012
Slide 7 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Project objective
• Develop wireless comms module for swallowable capsule
• In-body diagnostics
Battery/Standard Module
Comms & Application
Module
Antenna
26 mm
11 mmCamera
July 2012
Slide 8 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Existing Comms Transceiver
• Zarlink MICS Transceiver – ZL 70101•
• RF Band – 402 to 405 MHz
• Max data rate – 800 kbps
• FSK modulation
• Low power
July 2012
Slide 9 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Comms Requirements (1/2)• Primary function
– Transmit up to 6 x VGA quality images per second
• Translates to 1.5 to 3 Mbps– existing transceiver cannot achieve this data rate
• Other functionalities include:– temperature sensing– pH sensing– capsule status indication
July 2012
Slide 10 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Comms Requirements (2/2)
• Provide limited control of capsule (low data rate)– Toggle between sleep / active mode– Actuators control– Activation of biomarkers– Adjust image compression ratio
• RF Band – 921 to 924 MHz– antenna more compact in 900 MHz than in 400 MHz
band
• Low power
July 2012
Slide 11 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
PHY Layer Design (1/2)• Comms receivers are typically more complex than
transmitters
• Shift system complexities to external base station to reduce power
• Asymmetric comms link between in-body capsule and external base station
• Modulation:– Capsule – QPSK Tx / OOK Rx– Base station – OOK Tx / QPSK Rx
July 2012
Slide 12 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
PHY Design (2/2)• Error correction:
– Capsule• Reed-Solomon (255, 239) encoder• 1/3 repetition code decoder
– Base station• 1/3 repetition code encoder• Reed-Solomon (255, 239) decoder
• Data rates:– Capsule to base station – 3 Mbps– Base station to capsule – 50 kbps
July 2012
Slide 13 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Antenna Design• Capsule
– Coil antenna– Radiation – Omni-directional– Dimension – 5 x 5 x 5 mm3
• Station– Patch antenna– Radiation - Directional– Dimension – 100 x 100 x 4.6 mm3
July 2012
Slide 14 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
The Animal Trial
The standalone capsule
The capsule in pig’s stomach
July 2012
Slide 15 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Outline
• Background
• Wireless Transceiver design for In-body Diagnosis
• Wireless Transceiver for Implantable Device for
Diabetes Treatment
doc.: IEEE 802.15-12-0394-00-004n
Submission
• 286 million diabetics worldwide, 400 million by 2030
• ~10% of the Singapore population has diabetes
• 7th leading cause of death in Singapore ,
• ~US$116 billion was spent on the direct medical cost for diabetes
in 2007 (in US alone)
• All Type I and ~30% of Type 2 diabetics require insulin therapy
• Painful fingerpricks (blood glucose testing) and insulin injections
• Psychological aversion to the therapy non-compliance (as high
as 50%)
– Non- compliance increases the risk of developing systemic sequelae
Background and Motivation
July 2012
Slide 17 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
• Implanting of semi-permanent glucose-sensing and insulin-delivery components
- Medtronic, Johnson & Johnson, Roche, Abbott, and Animas
• New forms of insulin- Exubera by Pfizer, an inhaled form of insulin
(withdrawn due to fears of pulmonary side effects)
Some Available Advanced Solutions
July 2012
Slide 18 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
• Develop a proof-of-concept prototype for implantable close-loop glucose control
– A closed-loop glucose regulation algorithm
– A bench model for testing and developing the above algorithm
– A fail-safe system to prevent hypoglycaemia based on graded
alarms and glucose-insulin co-infusion
– A wireless transceiver
– A power management module with embedded wireless inductive
power charging capabilities
Our Objective
July 2012
Slide 19 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Lab Bench Prototype
Platform for Base Station(external unit)
Platform for Implantable Device(internal unit)
July 2012
Slide 20 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Lab Bench Prototype
Base Station Communicating with Implantable unit
July 2012
Slide 21 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Validation of Control AlgorithmCase 1 - Type 1 Patient Cases 2 and 3 – A Type 2 Patient
monitored in March and April 2011
Modeled glucose level and clinical data were shown in the top panel; and in the bottom panel the red dash curve and the green solid line represented glucose intake rate Gin (mg/dL) and insulin injection u (mU/min), respectively.
July 2012
Slide 22 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Test and Trial with Pork Meat
July 2012
Slide 23 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Prototype for Upcoming Animal Test
July 2012
Slide 24 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Power Management
• Energy consumption profiling– Conducted experiment on energy consumption profile of the
implant device in various operation modes
– Will be used to further optimize power management mechanism
• Energy harvesting/charging mechanism– Conducted experiments on resonant-based wireless power
transfer/charging
– Design is on-going
July 2012
Slide 25 Sumei Sun, I2R
doc.: IEEE 802.15-12-0394-00-004n
Submission
Summary and discussions
• Two wireless transceiver design projects have
been presented– One with short-life cycle, high data rate
– One with long life-cycle, moderate or low data rate
• Higher and higher demand for intelligent
healthcare/lifesyle management
– Calling for unified/inter-operable communication standard
doc.: IEEE 802.15-12-0394-00-004n
Submission
Thank You!
Q&A
July 2012
Slide 27 Sumei Sun, I2R
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