Doc Hernani Cualing CV

Curriculum Vitae

Hernani DM Cualing, MD

Hernani Del Mundo Cualing MD

Address: 18804 Chaville Rd., Lutz, Florida 33558

Telephone: 813-480-7849 (cell phone and blackberry )

813-909-4866 (fax )

Emails: [email protected]

[email protected]

[email protected]

Consultation Specialty: Hematopathology, Cutaneous Hematopoietic Lesions

Business: IHCFlow, Inc.

Website: WWW.IHCFLOW.com

Trademark: VirtualFlow IHCFlow™ Cytometer

Affiliation: Cutaneous Lymphoma Study Group, principal, USF/ Moffitt Cancer Center

Associate Professor, Department of Pathology and Cell Biology

University of South Florida College of Medicine

University of South Florida

12901 Bruce B. Downs Blvd.

Doctorate Education, Residency, Fellowship:

1970-1974 University of the Philippines

Quezon City, Philippines

B.S. Pre-Medicine

1974-1978 University of the Philippines School of Medicine

Manila, Philippines

M.D.

1987-1990 Resident in Anatomic and Clinical Pathology

Nassau County Medical Center, SUNY at Stony Brook Teaching Hospital

East Meadow, NY

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mailto:[email protected]



1990-1991 Chief Resident in Pathology and Surgical Pathology Fellowship, Nassau

County Medical Center under Dr. Vincent Palladino

SUNY at Stony Brook Teaching Hospital

East Meadow, NY

1991-1992 Hematopathology Fellow of Dr. R. Neiman and A. Orazi

Indiana University Medical Center

Riley Children’s Hospital

Indianapolis, IN

Post Graduate Training:

1978-1979 Rotating Internship- Pediatrics, Surgery, Medicine

Capiz Emmanuel Hospital

Roxas City, Philippines

1979-1980 Preventive Medicine Rural Training

University of Philippines Outreach Program

Dao, Panay Island, Philippines

1980-1982 Resident in General Surgery, University of the Philippines

Cardinal Santos Memorial Hospital

Greenhills, Manila, Philippines

1982-1985 Microbiology and Genetics, Post Doctorate MS Courses

University of Illinois at Chicago

Chicago, Illinois, USA

1985-1987 Research Fellowship in Membrane Tumor Biochemistry

Dana-Farber Cancer Institute under Dr. Emil Frei III Laboratory

Harvard Medical School

Boston,MA

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Awards and Honors:

1969-1971 Scholastic Delegate to Physics, Chemistry, Biology Interscholastic Competitions

Academic Excellence-Top Academic Rank, Section Class # 1 of 26 classes

Senior High School, Ramon Magsaysay High School,

Manila, Philippines

1976-1977 President of Medical Student Society

University of the Philippines College of Medicine

Manila, Philippines

1989-1990 First Prize Award, Resident Presentation in Pathology,

“Zell Ballen” Patterns in Organ of Zukerkandl

Nassau Society of Pathologist

East Meadow, NY

1990-1991 Chief Resident, Department of Pathology

Nassau County Medical Center, SUNY at Stony Brook Teaching Hospital

East Meadow, NY

1992-1993 Finalist, American Society of Clinical Pathologist

Spring Resident Presentation Competition

Boston, MA

1994-1995 Biomedical Engineering Seed Grant Award-Top Score

1994-1995.1.1.1 I Image Analysis of Lymphomas

University of Cincinnati University- Seed Grant Competition

Cincinnati, Ohio

1997-2000 Biomedical Engineering Grant Award

High “High Order Decision Theoretic Diagnosis of Lymphomas”

Whitaker Foundation ( National )

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2000-2001 Stratmore’s Who’s Who of North America

2003-2008 Marquis Who’s Who, 58th, 60th, 61st, in North America

2006-2008 Marquis Who’s Who, 6th Edition in Science and Engineering,

Marquis Who’s Who, 9th Edition in Medicine & Health

2003-2004 Awardee- Top Overseas Researcher


Medical School Alumni Association

Twenty-Five Year Homecoming Celebration, Manila, Philippines

2006 First Prize Research Presentation by Mentored resident

(Farah Khalil- Bone Marrow Quantitation )

Florida West Coast Assoc. of Pathologists/Pathology Alumni Assoc.

Longboat Key Conference, FL

2004-2005 Best Teacher of the Year Award

Awarded by AP/CP Pathology Residents

Department of Pathology

University of South Florida, Tampa, FL

2004-2007 Consultant: Immunohistochemistry and Histology Instrumentation

Council of Advisors for Health Care

New York, NY

2007-2008 Panelist: Small Business Innovations Research (SBIR/STTIR)

Grant

National Science Foundation

Bethesda, MD

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2007-2008 Mentor: Mentorship for Young scientist

International Society of Analytical Cytometry

Clinical Cytometry Society

Chicago, IL

2008 Consultant Adviser on Cutaneous Lymphomas

Advisory Board on Health Care

Eisai Corporation, Japan and USA

2007 FIRST Prize Research Retreat “Yoshinori Takahashi, D.

Coppola, N. Matshushita, H. Cualing, M. Sun, Y. Sato, C.

Liang, J. Jung, J, Cheng, J. Mule, WJ Pledger, Hong Gang Wang.

Bif-1 interacts with Beclin 1 through UVRAG and regulates

autophagy and tumorigenesis” 2007 Moffitt Scientific Retreat

publication, Blaise Alfano Conf.Center, Feb 24, 2007

2008 FIRST Prize Awardee Fellow Research Y.Takahashi,

D.Coppola,

N. Matshushita, H. Cualing, M. Sato, C. Liang, J. Mule, WJ

Pledger, Hong Gang Wang. H. Lee Mofttitt Cancer Center

Fellow Research Symphosium- Bif-1 in autophagy and tumorigenesis,

Stabile Bldg.

Basic Science Division, May 19, 2008

Licensures and Certifications:

2002-2010 Florida Medical License # ME 84854, Expiration Jan 31, 2012, Active, Clear

1998 4th International Symposium on Predictive Oncology and Therapy, Nice, France

1996 Lymph Node Pathology: ASCP Winter Seminar Certification, Orlando, FL

1994 T-cell Lymphomas-Comparison of Eastern and Western Experience: Hong Kong

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1992 Ohio Medical License #35-06-4174, Inactive

1992 Diplomate of American Board of Pathology, Hematology Subspecialty

1992 Indiana University School of Medicine, Hematopathology Fellowship Training

1991 Diplomate of American Board of Pathology, Anatomic and Clinical Pathology

1991 Lymph Node Pathology in the 90s (Bharat Nathwani), Washington DC

1990 New York Medical License #184512, Inactive

1990 Iowa Medical License #27672, Inactive

1991 ACLS(Advanced Cardiac Life Support) Certified, NY

1987 Lymphomas, Diagnosis from both sides of the Atlantic: Karl Lennert, Nassau, NY

1981 ECFMG Certification #322-877-2

1978 National Medical Licensure Certification, Philippines

Academic Appointments and Employment

1990-1991 Chief Resident

Nassau Country Medical Center, SUNY Stony Brook Campus

East Meadow, NY

1992-2001 Assistant Professor, Clinical

Attending Staff of Hospital

Department of Pathology and Laboratory Medicine

University of Cincinnati Medical Center, Cincinnati, Ohio

1994-2002 Course Director

Diagnostic Hematopathology

Year IV Medical Student Elective- UC-150146

University of Cincinnati College of Medicine

1993-1997 Medical Director

Hospital Phlebotomy Service

University of Cincinnati Medical Center

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1993-2002 Consultant: Hematopathology/Hematology Attending

Adams County Hospital Affiliate, Univ of Cincinnati

Cincinnati, Ohio

2001-2002 Co-Director, Hematopathology Fellowship Program

University of Cincinnati Department of Pathology and Lab Medicine

Cincinnati, Ohio

2002- Associate Professor, Anatomic and Clinical Hematopathology


Cincinnati, Ohio

2002-present Associate Professor, Clinical

University of South Florida, Department of Pathology and Cell Biology

Tampa, Florida

2002-present Associate Member and Attending Staff,

Department of Oncologic Sciences, Division of Hematopathology and Laboratory

Medicine, Moffitt Cancer and Research Institute

Tampa, Florida

Clinical appointments

1987-1991 Resident in Anatomic and Clinical Pathology,


East Meadow, NY

1990-1991 Chief Resident


East Meadow, NY

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1991-1992 Clinical Fellow in Hematopathology

Indiana University Medical Center

Riley Children’s Hospital

Indianapolis, IN

1992- 2002 Surgical Pathologist Attending Staff

Department of Pathology and Laboratory Medicine

University of Cincinnati Medical Center and Holmes Hospital

Cincinnati, OH

1993- 2002 Consulting Hematopathology Staff

Department of Pathology, Veterans Administration Medical Center

Cincinnati, OH

1996- 2002 Consulting Hematopathology Staff, Adams County Hospital

Adams County, OH


Flow Cytometry and Immunology Division

Health Alliance of Greater Cincinnati, Inc.

Cincinnati, Ohio

2002-present Hematopathology Attending Staff,

Department of Interdisciplinary Oncology/ Oncologic Sciences

Moffitt Cancer Center and Research Institute

Univ of South Florida College of Medicine Clinics,

Tampa, Florida

Heme Malignancies Pathologist

Lymph Nodes, Extranodal Tissue and Bone Marrow Diagnostic Service

Duties: Signs out Flow cytometry, coagulation molecular testing, peripheral blood, bone

marrow, lymph nodes, spleen, cutaneous lymphomas, GI Renal Lung Brain and other

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extranodal lymphoma work up biopsy, core biopsy specimens of suspected hematologic

malignancies, Reactive and Non neoplastic Hematopathology

Department Case Load: 3800 bone marrows, about 600 lymph nodes and FNAs, 1800

flow cytometry, 600 molecular and blood studies including CISH, FISH, and 22,000

immunohistochemistry tests per year.

2005-present Expert Consultant on Lymphomas and Cutaneous lymphomas

Contract consultant for lymphomas and leukemias involving lymph nodes and

cutaneous and other extranodal tissues

Quest Diagnostics, Fowler Av., Tampa, Florida

2009-present Expert Consultant on Cutaneous Lymphomas

Dermpath Diagnostics, Ameripath, Tampa, FL

Administrative:

2007 Course Co-Director: First Annual Cutaneous Lymphoma seminar, MCC

Cutaneous Cooperative Group: Dr. Frank Glass and Dr. Lubosh Sokol

University of South Florida, Tampa FL

2008 Course Director, 2nd Annual Cutaneous Lymphoma Seminar

With Patients Participation

Lake Buena Vista Resort,Orlando, Florida ( April 19 and April 20 )

Faculty from Boston, Rhode Is. and Florida : Organized the logistics, topics, scope and

faculty roles plus facilitated the direct participation of three lymphoma patients as

speakers.

2002-2008 Medical Director of Immunohistochemistry/Histology

Division of Pathology, Hematopathology and Laboratory Medicine

Department of Interdisciplinary Oncology,

H. Lee Moffitt Cancer Center and Research Institute,

Tampa, Florida.

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Role: Guide strategic direction as well as supervise day to day quality assurance issues in

histology and immunohistochemistry, chromogenic and fluorescent in situ hybridization,

and special stains supervising 8 FTE histotechnologists and 2 Lead Techs and 1

supervisor with a total of 22,000 annual antibody and in situ hybridization panels.

:Quality Assurance and CAP survey reporting results

:Signed off on Histo-Immunology procedures

: Monitored technologist CAP inspection preparation

: Introduced panels and monitored the more than 135 monoclonal antibodies used in

Surgical and Hematopathology Divisions

: Performed Quality and Cost Effectiveness evaluations for histology and automated

immunohistochemistry instruments

5 Ventana Nexes and 2 Benchmarks, Leica Instruments

2006-2010 Program Director,

Hematopathology Fellowship Training Program

USF- Moffitt DIO and Department of Oncologic Sciences


Tampa, Florida

Role: Administrative and Teaching-10 % time allotment

Programmatic direction and maintaining Accreditation in American Council of

Graduate Medical Education ( ACGME Hematopathology Program)

2008- Directed program that obtained the 5 year ACGME Full accreditation

Recruitment of fellows

2007 cycle – evaluated 33 applicants candidates for 1 year or 2 year track

2008 cycle – evaluated 32 applicants candidates

2009 cycle- evaluated 34 applicants

Supervision of Fellows

Immediate Past fellows:

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Supervised and advised two fellows that graduated 2007 and 2008

Current Fellows:

Supervised and advised two 2-year track fellows

:Directed the fellowship rotation: location, content, and quality

: Program Information Plan- monitored and evaluated the competency-based

training of hematopathology fellows according to ACGME approved PIF

: Assignment of mentors and direction of research projects for fellows;

: Administrative meeting with fellows regularly for assessment and feedback;

: Liason with teaching faculty regarding fellows issues

: Directs 2 Fellowship Coordinators and 1 Secretarial Assistant

: Selection and directions for the teaching faculty - 4 hematopathologists, 1

Molecular Pathologist, 2 Heme Oncologist, 2 Molecular Cytogeneticist, and 1

Pediatric Hematopathologist that are based from MCC, VA Haley Medical

Center and All Children’s Hospital.


Health Alliance of Cincinnati, Immunology

Diagnostic Immunology: Protein Electrophoresis, Serology interpretation,

Flow Cytometry Interpretation of Leukemias and Lymphomas,

Diagnostic Flow Cytometry, Health Alliance of Greater Cincinnati

Diagnostic Immunology, FISH, CISH, Health Alliance of Greater Cincinnati

Cincinnati, Ohio

Role: Oversaw the medical /scientific direction and daily quality issues

Supervised Flow Cytometrist 5-FTE in Flow Cytometry and 6 immunology

FTE technologist in immunology division

Reviews daily results including those with discrepancies and gating issues

Liason with clinicians


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University of Cincinnati Medical Center Phlebotomy Services

Liason with Clinicians and Nursing Staff regarding Blood Drawing Issues

Cincinnati, Ohio

1992-1999 Surgical Pathology and Hematopathology Sign-out including incorporation of flow

cytometry and gene rearrangement results in reports

University of Cincinnati Department of Pathology

Cincinnati, Ohio

1992-2002 Lymphoma Frozen Tissue Bank Database Director

University of Cincinnati Pathology and Hematopathology

Cincinnati, Ohio

Service:

Committee activities:

1990-2002 Deans Residency Review Committee, Resident Member

Nassau Country Medical Center, East Meadow, NY

1994-2002 Director

Telepathology Link Committee with Adams Country Hospital

Cincinnati, Ohio

1998-2002 Member

Scientific Advisory Committee

Confocal and Image analysis instrumentation

2000-2002 Co-Chair with Paul Hurtubise, PhD

Flow Cytometry and Immunology Methods Committees

Health Alliance of Greater Cincinnati

Cincinnati, Ohio

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2000-2002 Member

Hematopathology Fellowship committee

ACGME Accredited Fellowship, University of Cincinnati

Cincinnati, Ohio

2001-2002 Member

Health Alliance of Greater Cincinnati Bone marrow CAP compliance

Committee, University of Cincinnati

Cincinnati, Ohio

2000-2002 Hematology Sophomore Teaching Block Course Review Committee,

University of Cincinnati College of Medicine, Cincinnati, Ohio

2004-present Member, Resident Teaching Task Force Committee in Pathology

Moffitt Cancer Center, USF and DIO

Tampa, FL

2005-present Member, Graduate Medical Education Committee,

Moffitt Cancer Center GME

2006-present Pathology Teaching Committee member

Department of Pathology and Cell Biology

University of South Florida, Tampa, Florida

2006-present Graduate Medical Education Committee Member,

University of South Florida College of Medicine

USF, Tampa, Florida

2006-2007 Moffitt Cancer Center Appointment Promotion Tenure Committee Member

Department of Interdisciplinary Oncology, Tampa, Florida

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2007 Internal Reviewer faculty for USF GME office for Pediatric Pathology

Fellowship ACGME accreditation

2007-2007 Graduate Council- University Wide, University of South Florida, member

Fellowship subcommittee: reviewed many Thesis and PhD dissertations for

Presidential and other Scholastic University Wide awards

2007-2010 Policy Review Team Committee, member, MCC Policy Administration,

Moffitt Cancer Center and Research Institute, Tampa, Florida

2009 Internal Reviewer faculty for USF GME office for DermatoPathology

Fellowship ACGME accreditation

Community Service:

1972-1974 Coordinator- Free Medical Clinic Foundation, Premedical Student Branch,

University of the Philippines Outreach to Indigent Urban localities that

schedules medical doctors, free medicines and patients

1973-1978 Volunteers Association of the Philippines Member

Coordinated Free Cataract Surgery for indigents in Lubang Is. Performed by

the Chiefs of Ophthalmic and Neurosurgery Divisions,

Philippine General Hospital, University of the Philippines.

1973-1978 Trained in Acupuncture Medicine by Chinese Acupuncturist and conducted

Free acupuncture services to indigent rural folks, also provided acupuncture

anaesthesia to the Department of Orthopedic Surgery, University of the

Philippines for senior citizens undergoing Decubitus Ulcer debridgement and

Relief of Post Surgical Ileus

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1974-1976 Organizer and Founder of Medical Student Annual Musical and Talent

Extravaganza –“Tao Rin Pala”- University of the Philipppines College of

Medicine,Manila, Philippines

1976-1978 Organizer

Medical Student Liason for Disaster Relief Prepareness committee

University of the Philippines Office of the Dean, College of Medicine

1979-1980 Organizer, Herbal Medicine Cooperative Group of Rural “Herbolarios”

Compiled the Dao, Panay Island indigenous Flora with Medicinal Uses and

Converted the extracts to pills and emulsions for free medicines

1988-1990 Resident In Charge of Seminar Projectors and AudioVisual Aids to Speakers,

Nassau County Society of Pathologists, East Meadow, NY

1998-2002 Cutaneous Lymphoma Cooperative Group, CTCL patient education seminars

and journal clubs

2003-2004 Alumni Fund raising committee member to benefit University of Philippines

College of Medicine Library, Manila, Philippines

2005-2007 Southwest Florida Committee member for Alumni Affairs

University of the Philippines College of Medicine, Tampa, Florida

2007 Telepathology -Outreach Tumor Board Hematopathologist, for MCC

Parish Medical Center Leukemia Lymphoma Cases

2009 Cutaneous Lymphoma Foundation Patient Education Series

Cutaneous Lymphoma Overview Speaker- Use of modern modalities in early

CTCL diagnosis Feb 21, 2009, Sheraton Venue, Tampa, FL

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Professional Association Memberships:

1987- 1991 American Association for Advancement of Science

1987- 1991 Nassau Society of Pathologists, resident member

1991- present Fellow of the College of American Pathologists, sustaining member

1992 – 2002 Cincinnati Society of Pathologists, member

1992- 2002 Society for Hematopathologists,member

1993- 2002 Southwest Oncology Group, member

1993- 2000 Cutaneous Lymphoma Cooperative Group, Univ of Cincinnati

1996- 2000 Ohio State Society of Pathologists

1996- present International Academy of Pathologists-USCAP

1996- 2000 American Society of Clinical Pathologists

1998- 2002 The International Society for Optical Engineering

1999- 2002 International Society of Preventive Oncology

2002 -present Moffitt Cancer Center and Research Inst. In-residence

2002 -present American Society of Hematology

2006-2010 International Society of Analytical Cytology

2010 American Society of Tropical Medicine and Hygiene

Teaching experience:

University Courses/Advisory Role:

1991-1992 Clinical Instructor

Indiana University Medical School

Sophomore Clinical Hematology Laboratory Course

1992- 2002 Course Instructor: Lecturer

Hodgkin and Non Hodgkin Lymphomas


Medical Student Sophomore Pathology Lecture series

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1992- 2002 Course Instructor: Laboratory Session

Leukemias, Anemias, Lymphomas


Medical Student Sophomore Pathology Lecture series

1994- 2002 Course Director

Medical Student Diagnostic Hematopathology

Year IV – Elective Course , University of Cincinnati

Hematopathology Student Papers/Reports: Andrew Mone, Alena Goldman, Yaron

Goldman and others

1994-1995 Thesis Advisor

Masters in Computer Science

Graduate student-Thia Balachander

“Algorithms in the Image Understanding of Features of Lymphoma Cells”

Master Degree of T. Balachander on Image Analysis of Lymphoma/Leukemia cells

1997-1998 Thesis Co-advisor

PhD in Computer Science

Graduate Student- T Balachander and R. Lotlikar

Image analysis and Neural Network Diagnosis of lymphoma/leukemia Cytologic

Romanosky stained Preps

1997-1998 Project Director for Students in programming an Automatic Image Acquisition using

X,Y,Z moveable microscope stage

Whitaker Foundation funded project with Professor R. Kothari

Lymphoma Diagnosis using Artificial Intelligence

1999 and 2001 Project Director for programmatic activity with MS Engineering Student using Oncor

Image, Seed Funding from Dr. Roger Smith

2000 Diagnostic Hematology Elective Medical Student Mentor – Yaron Goldman

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2001 Medical Student Adviser- Sukjinder Singh

2001 Diagnostic Hematology Medical Student (Year IV) Electives Mentor-

Andrew Mone

2002 Diagnostic Hematology Medical Student (Year IV) Electives Mentor-

Michael Tuchfarber, Alena Goldman that generated case reports

2003 BMS 6600 Hematology Block Course Faculty,

Lectures and Laboratory Courses


2006 USF Medical Student Teaching (Year IV )

Preceptorship Interdisciplinary Oncology

College of Medicine Course: BCC8117

Hematopathology preceptorship: Jeremy Bowers , T. Condarco that generated a case

report


2007 Medical Student Mentor to Michael Fuller and Elizabeth Sundean

Year IV Medical Preceptorship in Pathology; BCC8117

Other Courses and National Symposia:

Regional seminars

Mar 17, 2000 Seminar Series sponsored by Cincinnati Society for Pathologists

“Flow Cytometric Immunophenotyping of Hematologic Disorders”

Cincinnati, Ohio

May 26, 2001 “Cutaneous Lymphoma in a Child-“ invited speaker

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TriState Midwest Pediatric Pathology Conference

Sponsored by Cincinnati Children’s Hospital

Cincinnati, Ohio

April 28, 2007 Seminar Lecture: “WHO-EORT Classification of Cutaneous Lymphomas”

Co-director of 1st Annual Cutaneous Lymphoma Seminar, Sponsored by USF Health.

Cutaneous Lymphoma Foundation, Moffitt Cancer Center, Tampa, Florida targeted

Florida Dermatologist, Pathologists, Dermatopathologists and Oncologist

Sept 4, 2007 COBRE Research Rounds- Core of Biomedical Research Excellence Invited Speaker on

“Emerging Vision Analysis applicable to Tissue Bioengineering and Research”-

Sponsored by Dept of Dermatology, Boston University: Roger Williams Medical Center

with Dr. Vince Falanga host, Providence, Rhode Island

National seminars

Apr 14, 1994 Course Lecturer: “Lymphomas of the Skin and the Role of the Laboratory”

Sponsored by Abbott Pharmaceutical and Nebraska-Iowa Medical Technologist

Societies, Des Moine, Nebraska

Apr 24, 1995 Course faculty Lecturer:

Hematologic Malignancies-overview

Peripheral Blood in Hematologic Malignancies

Review for Hematology Oncology Fellow Board Examination

Sponsored by Osler Institute Review

Cincinnati, Ohio

April 28, 2007 Co-director of 1st Annual Cutaneous Lymphoma Seminar, Moffitt Cancer Center,

Tampa, Sponsored by Moffitt Cancer Center Foundation and jointly with Cutaneous

Lymphoma Foundation- Update on Skin Lymphomas

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April 19, 20 2008 Director of 2nd Annual Cutaneous Lymphoma Seminar,

Sponsored by Cutaneous Lymphoma Foundation, USF Health, Moffitt Cancer Institute

and Funded by Eisai Corporation, and other National Pharmaceutical Corporations

Lake Buena Vista Resort, Orlando Florida

This two day seminar included three patients as speakers and Faculty from International

Cutaneous Lymphoma Study Group, Harvard Medical School Faculty and attended

nationally by Dermatologist, Pathologists, Oncologists and some attendees from out of

the country.

International lectures/ Presentations:

1994, Fall “Macrosplenomegaly with hemophagocytosis in AIDS”

Presented in oral platform in XX International Congress of the International Academy

of Pathology, Queen Hospital, Hong Kong

1998 October ” Immunophenotypic Diagnosis of Acute Leukemia Using Decision Tree Analysis”

Presentation in International Academy of Pathology, Nice France,

Serialized in Archives d’Anatomie et de cytologie pathologiques: Clinical and

Experimental Pathology.

1999 (July 8-24) Hematology Course Block Lecturer and Course Director for two weeks

Lectured to 2nd year medical Students for about 30 contact lecture/ laboratory hours on

Leukemias and Lymphomas and Benign Hematology

Distributed a 168 pages course handout and 2 hour block examination

Sponsored by St. Mathews University School of Medicine

Ambergis Cay, Belize

2000 Feb 25 Grand Rounds in Pathology. “REAL Classification of Lymphomas” .

Sponsored by Univ of the Philippines Department of Pathology seminar,

Pedro Gil, Metro Manila, Philippines

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2001 Jan 15 Invited Course lecturer on “Lymphomas and the role of immunohistochemistry and

Flow Cytometry In diagnosis”

Department of Pathology Seminar Series


Metro Manila Philippines

Proceedings in Research Meetings:

1. Bernal SD, Cualing HM, Elias AD. Stability and shedding of small cell carcinoma

membrane antigens: applications to detection of antigens in marrow and serum.

Lung Cancer 1988; 4:79-80.

2. Bosserman L, Tanaka I, Cualing H, Elias A, Skarin,

Dreyfuss A, Bernal S. Serum Radioimmunoassay Detects

SM1 antigen in Lung Cancer patients. Proc Am Soc Clin

Onc 5:174 Mar 1986.

3. Wright J, Cucci C, Flatow J, Rosowski A, Cualing H, Bernal

S and Frei III E. Detection of two active Dihydrofolate Acid

Reductase forms in Squamous cancer of the Head

and Neck cell lines using monoclonal antibodies. Proc of Am

Soc Clin Onc Mar 1987.

4. Wright J, Cucci C, Rosowski A, Cualing H, Bernal S, Koch J,

Waxman D and Frei E. Dihydrofolate Reductase from

Methotrexate Resistant Human Squamous Cell Carcinoma for

Monoclonal Antibody generation. Proc of Am Assoc Cancer

Res 28:1175 1987.

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5. Yoshinori Takahashi, D. Coppola, N. Matshushita, H. Cualing, M.

Sun, Y. Sato, C. Liang, J. Jung, J, Cheng, J. Mule, WJ Pledger, Hong

Gang Wang. Bif-1 interacts with Beclin 1 through UVRAG and

regulates autophagy and tumorigenesis, 2007 Moffitt Scientific

Retreat publication, Blaise Alfano Conf.Center, Feb 24, 2007-

FIRST Prize awardee presentation

6. Yoshinori Takahashi, D. Coppola, N. Matshushita, H. Cualing, M.

Sato, C. Liang, J. Mule, WJ Pledger, Hong Gang Wang. H. Lee

Mofttitt Cancer Center Fellow Research Symphosium- Bif-1 in

autophagy and tumorigenesis.FIRST Prize awardee presentation

Basic Science Division, May 19, 2008

Other CME Lectures

Aug 1, 1992 “Peripheral T-cell lymphoma presenting as Angiocentric Waldeyer’s Ring Lesions “

Clinico Pathology Conference, Sponsored by Internal Medicine

University of Cincinnati Medical Center, Ohio

Aug 9, 1994 “Lymphocytes and their Markers in the Skin “

Joint Department of Dermatology and Hematology-Oncology Grand Rounds


Sept 2, 1994 “Understanding the Histologic Classification of Hodgkin’s and Non-Hodgkin’s

Lymphoma” Hematology-Oncology special seminar


Sept 22, 1995 ”Cytophagic Histiocytic Panniculitis”

Hematology -Oncology Grand Rounds


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May 11, 1996 “Sea Blue Histiocytes and Lecithin Cholesterol Acyltransferase Deficiency”

Hematology Oncology Grand Rounds


Nov 8, 1996 Amyloid and Enlarged Tongue”

Clinical Pathology Conference Sponsored by Internal Medicine


Jan 6, 1997 “REAL (Lymphoma) Classsification”

Grand Rounds in Pathology


Dec 12, 1997 “Cat Scratch Disease”

Clinical Pathology Conference Sponsored by Internal Medicine


Jan 5, 1998 “WHO Classification Hematologic Diseases”



June 22,1998 “Extranodal Lymphomas”



Jan 11, 1999 “Update of WHO Classification of Lymphoid Neoplasms”



June 13, 2000. “Ocular adnexal Lymphoproliferations and Pseudotumors”

Department of Opthalmology Grand Rounds

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Aug 11, 2000 “Multiple Myeloma”

Clinico Pathology Conference, Sponsored by Internal Medicine


Jan 26, 2001 “Mantle cell lymphomas”

Morbidity and Mortality Conference- Sponsored by Hematology Oncology


April 11, 2001 “Gene Structure and Clonality”

Immunology Rounds Sponsored by Health Alliance of Greater Cincinnati


April 16, 2001 “Reactive Lymphadenopathies”



April 25, 2001 “Immunoproliferative Diseases”

Immunology Rounds Sponsored by Health Alliance of Greater Cincinnati


Aug 9, 2001 “Cutaneous Lymphoproliferative Diseases”

Dermatology Grand Rounds


Aug 27, 2001 “Lymphocytes – From Biology to Diseases” ( 2 hours)



Sept 21, 2001 “Advances in Image Cytometry in Hematopathology”

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Moffit Cancer Center and Research Institute Grand Rounds in Pathology

Tampa, Florida

Jan 4, 2002 “Multidimensional diagnosis in Hematopathology”

Grand Rounds in Hematology Oncology


Feb 4, 2002 “Diagnostic Advances using Image Cytometry”



Oct 21, 2002 “Understanding the WHO Classification of Lymphomas”

Moffitt Hematologic Malignancies Series-

Sponsored by Hematologic Malignancies

Moffitt Cancer Center, Tampa, Florida

April 10, 2003 “T-cell Prolymphocytic Leukemia”

Interesting Case Presentation- Tuesday VA Rounds

Hematologic Malignancies

Moffitt Cancer Center, Tampa, Florida

Nov 12, 2003 “Patterns in Benign and Malignant Lymphoproliferations”

Pathology Grand Rounds Series


Tampa, Florida

Mar 2, 2004 WHO Classification of Lymphomas-B cell Malignancies



Tampa, Florida

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Apr 7, 2004 WHO Classification of Lymphomas-T cell Malignancies



Tampa, Florida

March 10, 2006 WHO/EORTC Cutaneous Lymphoma- From Biology to Disease-Update



Tampa, Florida

April 14, 2006 Functional microanatomy and Diseases of the Spleen- Biology to Disease Series



Tampa, Florida

Oct 13, 2006 Aggressive cutaneous peripheral T cell lymphomas and CD30 lymphomas



Tampa, Florida

Nov 16, 2007 Update on Cutaneous Lymphomas- What’s New and What is Revised



Tampa, Florida

Nov 20, 2007 B-cell lymphomas- Biology to Disease Series



Tampa, Florida

Nov 30, 2007 T-cell lymphomas- Biology to Disease Series

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Tampa, Florida

Residency Fellowship Directed Unknown Slides and Diagnostic Workshops

May 19, 2004 Hemepath unknowns slides resident conference-Preceptor

June 16, 2004 Hemepath unknowns slides resident conference-Preceptor

July 21, 2004 Lymphocytes-from Biology to Diseases.

August 18, 2004 Major Patterns of Reactive Lymph node Hyperplasia and Cases

Hemepath unknowns slide resident conference-Preceptor

Sept 1, 2004 Peripheral T cell lymphomas and Cases-Preceptor

Sept 29, 2004 Cutaneous Lymphomas and Cases

Oct 13, 2004 Hematology-Oncology Fellows Teaching Rounds- Immunohistochemistry: Applications

Oct 27, 2004 Pathology of Spleen and Cases

Nov 24, 2004 Pattterns of Lymph node Disorders and Cases

January 18,2005 WHO Classification of Lymphomas- B cell type

January 21, 2005 WHO Classification of Lymphomas- Peripheral T cell Lymphomas

July 19, 2005 Immunohistochemistry: Applications/ Theory/ Techniques in Histology

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December 20, 2005 Hematopathology Resident Lecture Slides Series- Pathology of the Spleen

April 25, 2006 ASH paper Clinical Pathology presentation: New Technology of IHCFlow

May 16, 2006 Lymph node Reaction and Pattern of Benign Lymphadenopathies: Biology to Disease

Slide Series

June 13, 2006 Reactive lymph node- unknown slide workshop with residents and fellows

July 14, 2006 Advanced Immunohistochemistry Resident Lecture with Demos

Nov 21, 2006 Workshop on hematopathology diagnosis-competency based training on Potpourri of

Cases

Dec 20, 2006 Grand Round- B cell lymphomas

March 10, 2007 Teaching Rounds in Pathology- Splenic pathology and benign disorders

April 14, 2007 Grand Rounds- Cutaneous Lymphomas

July 24, 2007 Introduction to Histology and Special Immunostains II- Pathology Lecture

Nov 13, 2007 Lymphocytes from Biology to Disease Series- Reactive Lymph Nodes

Teaching Series

2005-2006 Hematopathology Lecture Series for Residents and Fellows-

Dec, 2005 to May, 2006

2007-2008 Hematopathology Fellow Teaching -Slide Weekly Slide Workshop Series

2007-2009 Hematopathology Fellow Teaching -Slide Weekly Slide Workshop Series

ACGME accredited Hematopathology Fellows 2006-2008 Dorna Rezania MD

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2007-2008 Tina Yu MD

2008-2009 Elizabeth Sagatys MD

2009-current Mojdeh Naghashpour, MD

FELLOW SCHOLARLY ACTIVITY

A. List the articles authored or co-authored by fellows in your program

Name of Fellow, Graduation year ( Current Fellow, clinical)

Author(s) (Fellow Name in bold), Name of article, Name of journal, Volume, pages, month Year

Mojdeh Naghashpour MD,2010

M. Naghashpour, H. Cualing, M. Szabunio, M. Bui, “Hyaline-Vascular Castleman Disease: A Rare Cause of a Solitary Subcutaneous Soft Tissue


M. Naghashpour and H. Cualing “Splenomegaly with Sea-Blue Histiocytosis, Dyslipidemia and Nephropathy in a Patient with Lecithin Cholesterol Acyltransferase (LCAT)


Rebecca L. Olin, Kim E. Nichols, Mojdeh Naghashpour, Mariusz Wasik, Brenda Shelly,Edward A. Stadtmauer, and Dan T. Vogl1 “Successful use of the anti-CD25 antibody daclizumab


Mojdeh Naghashpour and Lynn C. Moscinski, “Lymphoma”, in “Cancer Growth and Progression, 2 nd edition; Volume 2; Mechanisms of Carcinogenesis”, Springer 2009.

Name of Fellow, Graduation year

Author(s) (Fellow Name in bold), Name of article, Name of journal, Volume, pages, month Year

Elizabeth Sagatys MD 2009

Condarco T, Sagatys E, Prakash A, Rezania D, Cualing H. Primary Cutaneous B-Cell Lymphoma in a Child. Fetal and Pediatric Pathology.


Sagatys E, Messina J, Rojiani A. 55-Year-Old Man with Paraspinal Mass.Brain Pathology. 18(4):631-5.2008


Saeed S, Sagatys E, Wasserman J, Morgan MB. Geriatric Fungal Infections. In: Diagnosis of Aging Skin Diseases, RA Norman (ed). pp 121-47.

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Sagatys E, Garrett C, Boulware D, Kelly S, Malafa M, Cheng J, Sebti S, Coppola D. Activation of the Serine/Threonine Protein Kinase Akt


Saeed S, Sagatys E, Morgan MB. Acral Keratosis with Eosinophilic Dermal Deposits: A Distinctive Clinicopathologic Entity or Colloid

Yu, I-Ting (Tina), 2008 IT Yu, LC Moscinski, L Sokol, HD Cualing. CD4+CD56+ hematodermic neoplasm clinicopathologic study of eight cases. AJSP (manuscript for


Author(s) (Fellow Name in bold), Name of Article, Name of Journal, Volume, pages, Month Year

Dorna Rezania, 2007 Rezania D, Cualing HD, Ayala E. The diagnosis, management, and role of hematopoietic stem cell transplantation in aggressive peripheral T-cell neoplasms. Cancer Control. 2007 Apr; 14 (2).

Dorna Rezania, 2007 Rezania D, Sokol L, Cualing H. Classification and treatment of rare and aggressive types of peripheral T-cell/natural killer-cell lymphomas of the skin. Cancer Control. 2007 Apr; 14 (2).

Dorna Rezania, 2007 Rezania D, Ouban A, Marcet J, Coppola D. CMV colitis mimicking recurrent inflammatory bowel disease: report of three cases. Am Surg. 2007 Jan; 73 (1).Dorna Rezania, 2007 Todd J. Alekshun, MD, Dorna Rezania, MD, Hernani Cualing, MD, Ernesto Ayala, MD, Lubomir Sokol, MD. Skeletal Muscle Peripheral T-Cell Lymphoma, Journal of Clinical Oncology,Jan 20 ;26:501-3,2008

Dorna Rezania, 2007 Tania Condarco, MD, Elizabeth Sagatys, MD, Dorna Rezania, MD, Amy Prakash, MD, Hernani Cualing, MD. Primary Cutaneous B-cell Lymphoma in a Child. Pediatric Dermatology,Fetal and Pediatric Pathology, 2008 Dec 27:206-14

Dorna Rezania, 2007 Erica Smithberger MD, Rezania Dorna MD, Chavan R, Lein MH, Cualing H, Glass F, Messina JL. Primary Cutaneous Angioimmunoblastic T-cell lymphoma Histologically Mimicking an Inflammatory Dermatosis. Submitted Archives of Dermatology

B. List the research presentations by fellows (during the last three years) that resulted from fellow research activity during the program.


Presenter(s) (Fellow Name in bold), Topic, Audience (or Name of Meeting), Location, Date

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Mojdeh Naghashpour, MD

EM Sagatys, D Rezania, M Naghashpour, LF Glass, ME Kadin and HD Cualing “CLA, TRAF1, BCL2, NFKB2, CD56, EMA and Fascin


Naghashpour M, Sagatys E, Smith R, Cualing H. “AIDS-Associated Hemophagocytic Syndrome: A Study of 100 Autopsy Cases” Oral Platform


Mojdeh Naghashpour, Adam Bagg. “The complementary role of molecular genetic and conventional cytogenetic detection of diagnostically and


M. Naghashpour, Ahmed S Bedeir, Jed Di-Paola, Yuan Yao, Roger Day and AR Sepulveda1. (United States and Canadian Academy of Pathology 98th Annual Meeting Stowell-Orbison Poster SessionBoston, Massachusetts Elizabeth Sagatys, MD 2009 CLA, TRAF1, BCL2, NFKB2, CD56, EMA and Fascin Expression in CD30+ Lymphoproliferative Disorders of the Skin EM Sagatys, D Rezania, M Naghashpour, LF Glass, ME Kadin, HD Cualing

United States and Canadian Academy of Pathology 98th Annual Meeting Stowell-Orbison Poster SessionBoston, Massachusetts 2009Elizabeth Sagatys, MD

2009Elizabeth Sagatys MD, Dorna Rezania MD, MD, Marshall Kadin MD, Frank Glass MD, Hernani Cualing MD. CLA and TRAF1 are useful in differentiating lymphomatoid papulosis, cutaneous ALCL, and Systemic ALCL. Am Society of Hematology poster, 2008, San Francisco.

Elizabeth Sagatys, MD 2009

AIDS-Associated Hemophagocytic Syndrome: A Study of 100 Autopsy Cases M Naghashpour, EM Sagatys, R Smith, HD Cualing

United States and Canadian Academy of Pathology 98th Annual Meeting Proffered Paper - Infections Session Boston, Massachusetts, 2009Elizabeth Sagatys, MD

2009Analysis of T-cell Subpopulations in the Lymph Nodes of Patients with Mantle Cell LymphomaEM Sagatys, L Moscinski, S Dessureault, E Sotomayor, H Cualing American

Elizabeth Sagatys, MD 2009

Automated Determination of Bone Marrow CellularityEM Sagatys, H Cualing, L Kang, E Zhong, L Moscinski

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Yu, I-Ting (Tina),2008 IT Yu, D Rezania, LC Moscinski, JD Messina, HD Cualing. Differentiating Cd4+/Cd56+ Hematodermic Neoplasm From Acute Monoblastic Leukemia. United States and Canadian


Presenter(s) (Fellow Name in bold), Topic, Audience (or Name of Meeting), Location, Date

Dorna Rezania, 2007 Dorna Rezania, MD, Hernani D. Cualing, MD, Eric Zhong MS, Lihua Li PhD. Conversion of Tissue Chromogenic Staining to Virtual Flow Cytometry by iHCFLOW System, United States and Canadian Academy of Pathology (USCAP), annual meeting, SanDiego, CA, 03/2007

Dorna Rezania, 2007 Ghayouri, M, Rezania, D, I-Ting YU , Moscinski, L, Zhong, E. Cualing, H. Automated grading of the reticulin stain of bone marrows using AUTORETIC algorithm. Accepted for United States and Canadian Academy of Pathology (USCAP), annual meeting, Denver, CO, 03/2008

Dorna Rezania, 2007 I-Ting Yu, MD, Dorna Rezania, MD, Lynn C. Moscinski, MD, Jane D. Messina, MD, Hernani D. Cualing, MD. Differentiating CD4+CD56+ Hematodermic neoplasms from acute monoblastic leukemia. Accepted for United States and Canadian Academy of Pathology (USCAP), annual meeting, Denver CO, 03/2008Dorna Rezania, 2007 Elizabeth Sagatys Dorna Rezania MD, MD, Marshall Kadin MD, Frank Glass MD, Hernani Cualing MD. CLA and TRAF1 are useful in differentiating lymphomatoid papulosis, cutaneous ALCL, and Systemic ALCL. Am Society of Hematology, 2008, San Francisco.

Research Support-Clinical Trials:

Title: A Phase II Trial Using a Universal GM-CSF-Producing and CD40L-Expressing Bystander Cell Line

(GM.CD40L) in the Formulation of Autologous Tumor Cell-Based Vaccines for Patients with Mantle Cell

Lymphoma.

Account : MCC# 13840

Type: Foundation Grant

Dates: 2005-2008

Source: Lymphoma Foundation of America

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Role in the Study: Hematopathologist-Tissue Quantification of tumor infiltrating lymphocytes in mantle

cell lymphoma.

Title: Bortezomib and Vorinostat Trial in Refractory Mantle Cell Lymphoma

Account #: PI/Dr. Sokol Co Investigator: Hernani Cualing MD

Dates: 2008-2009

Source: H. Lee Moffitt Cancer Center

Role in the Study: Hematopathologist and quantification of target antigen

Title: “Medimmune anti CD2 targeted therapy in T cell lymphoma”

Account #: 14120 PI/Dr. Sokol Co Investigator, Hernani Cualing MD

Dates: 2006-2008


Role in the Study: Hematopathologist and quantifying target antigen

Title: “Single Agent Phase II study of Forodesine in the treatment of (CTCL) cutaneous T cell

lymphoma”

Account #: 14120 PI/Dr. Sokol Pathologist, Hernani Cualing MD

Dates: 2006-2008


Role in the Study: Hematopathologist and quantifying target antigen

Title: “Cytogenetic Studies in Leukemia Patients”

Account #: 14766 PI/Dr Lynn Moscinski, MD Collaborator/Hernani Cualing MD

Dates: 2007-2008


Account# 14794 PI/Lynn Moscinski, MD Collaborator/Hernani Cualing, MD

Date: 2007-2008


Title: Leukemia Centralized Reference Laboratories and Tissue Respositories, Ancillary

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External Grant:

1. Account: RC1 Application PI/George Blanck, Ph.D. Co Investigator/Hernani Cualing, MD

Source: National Institute of Health

Title: “Mouse modeling of a CD30+ lymphoproliferative disorder: Role of IRF-1 defects in ALCLs”

% Effort 10%

Role in Study: Co PI: Hematopathologist comparing human CD30+ lymphomas with mouse CD30+

lymphomas

Date Submitted: June 14 , 2009- Not funded, Resubmission SBIR

2. New Multiinstitutional Grant submitted April 27, 2009: Exploratory/Developmental Research Grant

(R21) via American Recovery & Reinvestment Act of 2009 as RFA to Translational Science and

specific Challenge Topic 15-CA-105, The Biology of Cancer in Adolescents and Young Adults.:

using tissue blocks from SEER tissue banks from Hawaii, Iowa, RI, USC

Samples consist of diagnostic tumors from 527 Hodgkin lymphoma patients in the National

Cancer Institute Surveillance, Epidemiology and End-Results (SEER) program

Residual Tissue Repository (RTR). In Los Angeles, Hawaii and Iowa.

% effort: 3 %

Role: To provide hematopathology support and know-how for automated virtual flow analysis of T cell

subsets immunostains on these blocks.

COMPLETED

Internal Grant:

PI/Dr. R. Kothari Co PI Investigator.Hernani Cualing MD

Dates: 1994-1995

Source: University of Cincinnati/College of Engineering Biomedical Engineering Grant

Title: “Intelligent image analysis of lymphomas using artifical neural networks

% Effort: 10%

Role in the Study: Hematopathologist performing diagnosis and image analysis

Total Amount of Award: $ 24,000

Internal Grant:

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PI: Director of Project Hernani Cualing MD

Dates: 1998-2000

Source: Dr. R Smith Discretionary Fund, Professor Univ of Cincinnati

Title: Color image segmentation of lymphocytes: Biomedical Engineering Grant

% Effort: 5 %

Role in the Study: Hematopathologist and quantification of target antigen

External Grant:

PI/Dr. R. Kothari Co Investigator.Hernani Cualing MD

Dates: 1997-2000

Source: Whitaker Foundation Biomedical Engineering Grant

Title: Microscopic Diagnosis of Lymphoma and Leukemia

% Effort: 15 %

Role in the Study: Hematopathologist performing diagnosis and image analysis

Total Amount of Award: $120,000

PATENTS and TRADEMARKS

1. USPTO/Virtual flow cytometry on immunostained tissue-Tissue cytometer

2. USPTO/ International PCT :Automated Cytomics: Bone Marrow Cellularity Determination

3. USPTO/ Automated Cytomics: Bone Marrow Reticulin Fibrosis Determination

4. USPTO Registered Trademark: VirtualFlow IHCFLOW® Cytometer

PEER REVIEWED JOURNAL REVIEWER:

Cytometry part B

Communications in Clinical Cytometry

Human Pathology

International Journal of Cancer

Transaction on Knowledge and Data Engineering

Leukemia Lymphoma

Pediatric Hematology

Pediatric Dermatology

Computer Methods and Programs in Biomedicine

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Peer reviewed publications:

1) Bernal S, Cualing H, Elias A., Schwarting G and McCluer R.

Classification of Small Cell Carcinoma Antigens by their Association

with Subcellular Components. Lung Cancer Journal 4: 99-102 1988.

2) Bernal S, Cualing H., Elias A and Siegel R. Stability and Shedding of

Small Cell Carcinoma Membrane Antigens: Applications to Detection

of Antigens in Marrow and Serum. Lung Cancer Journal. 4: 79-80 1988.

3) Pliskin A, Cualing H, Stenger RJ. Primary Squamous Cell Carcinoma of

the Liver Originating in a Congenital Cyst of the Liver. A Case

Report and Review of Literature. Arch of Path Lab Med. 116:105-107, Jan

1992.

4) Cualing H, Siegel R, Schwarting G, Suchy S, McCluer R and Bernal,S.

Expression of H-like blood group glycolipids in Small Cell Carcinoma of

the Lung. Hybridoma, 12(3):239-247, Jun 1993.*

5) Orazi A, Neiman R, Cualing H, Heerema N, John K. , CD34 Immunostaining of

Bone marrow biopsy specimens is a reliable way to classify the phases of

chronic myeloid leukemia. Am J Clin Pathol, 101(4):426-428, Apr 1994.

6) Kothari R, Cualing H. , Balachander T. Neural Network Analysis of Flow

Cytometric Immunophenotype Data. IEEE Transactions in Biomedical

Engineering, 43(8):803-810,Aug 1996.

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7) Cualing H, Povoski S, Fenoglio-Preiser C, Yassin R, Bell R. Characterization

of Hematologic malignancies in Syrian Golden Hamsters, Carcinogenesis

17(9):1983-1988,1996.*

8) Balachander T, Kothari R, Cualing H. An empirical comparison of

dimensionality reduction techniques for Pattern Classification. Gerstner W et al

eds. Artificial Neural Networks ICANN ’97, Lausanne, Switzerland. Lecture

Notes in Computer Science1327: 589-594, 1997.

9) Cualing H, Vasireddy R. Adult T-cell leukemia and Cutaneous pathology: An

overview. J Geriat Dermatol 5(8): 377-382, 1997.*

10) Giza E*, Stern P, Cualing H. Aggressive Giant Cell Reparative Granuloma of

the Metacarpal. J Hand Surg AM 22A (4): 732-736, 1997.

11) Massela F, Kowal-Vern A, Shrit A, Wibowo A, Rector J, Cotelingham J, Collier

J, Michael A, Cualing H, Schumacher H. Acute Erythroleukemia. Am J Clin

Pathol 110(5):590-598, Nov 1998.

12) Craig A*, Cualing H, Thomas G, Lamerson C, Smith R. Cytophagic

Histiocytic Panniculitis- a syndrome associated with benign and malignant

panniculitis: Case comparison and review of the literature. J Amer Acad

Dermatol 39(5):721-736, part 1 Nov 1998.*

13) Cualing H, Balachander T, Kothari R. Immunophenotypic diagnosis of acute

leukemia using decision tree analysis. Laboratory Investigation , 79(2): 205-212,

Feb 1999.*

14) Nakanishi K, Cualing H, Husseinzadeh N. Dermatomyositis as a presenting

symptom of ovarian cancer. Obstetrics and Gynecology 94(5): 836-838, part 2

Suppl S Nov 1999.

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15) Marcelo A, Fontelo P, Farolan M, Cualing H. Effect of Image Compression on

Telepathology: A Randomized Controlled Trial. Arch Pathol Lab Med,

124:1653-1656, Nov 2000.

16) Cualing H, Zellner D, Steele P. Blastic transformation of splenic marginal zone

B-cell lymphoma.. Arch Pathol Lab Medicine. 124(3):748-752 March 2000*

17) Cualing H. Perspectives: Automated Analysis in Flow

Cytometry.Communications in Clin Cytometry, 42:110-113, April 2000.*

18) Cualing H. Wang G, Noffsinger A, Fenoglio-Preiser C. Heterotopic ovarian

splenoma: report of a first case. Arch Pathol Lab Med. 2001 Nov;125(11):1483-

5.

19) Cualing H, Schroder L Perme I. Allergic Granulomatosis secondary to a

Limited Churg-Strauss Lymphadenopathy: Case Report with Histologic and

Immunophenotypic analysis- 125:954-957, 2001 Arch of Pathol Lab Med

July 2001

20) Gebrail F*, Knapp M, Perrotta G, Cualing H. Crystalline Histiocytosis in

Hereditary Cystinosis. 126:1135, Sept 2002, Archives of Pathol Lab Med.

(Direct supervision of medical student elective in Diagnostic Hematopathology)

21) Kulow G, Breneman D, Cualing H, Steele P, Breneman J, Van Horn J, Mutasim

D. The Progression of Cutaneous B-cell Pseudolymphoma (CBPL) to

Cutaneous B-cell lymphoma (CBCL). Vol 6(6), 519-528, Nov 2002, J of

Cutaneous Med and Surg.

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22) Gebrail F*, Lowy A, Cualing H. Angiolymphoid hyperplasia with eosinophilia:

a pathologic quiz case. Vol 127, 113-114, Jan 2003, Archives of Pathol

Lab Med. (Direct supervision of medical student elective in Diagnostic

Hematopathology)

23) Goldman A*, Bedolla G, Gebrail F, Cualing H, Bronchus-Associated

Lymphoid Tissue Lymphoma (BALT lymphoma). Vol 127, 115-116, Jan 2003,

Archives of Pathol and Lab Med. (Direct supervision of medical student elective

in Diagnostic Hematopathology)

24) Breneman DL, Raju US, Breneman JC, Steele PE, McFadden DW, Cualing HD,

Nussbaum MS, Swerdlow SH.Lymph node grading for staging of mycosis

fungoides may benefit from examination of multiple excised lymph

nodes. J Am Acad Dermatol. 2003 May;48(5):702-6.

25) Goldman A*, Gebrail F, Cualing H, Mott cell Granuloma: a 56 year old

presenting with recurrent neck mass. Vol 127: June 2003 Archives of Pathology

and Lab Medicine. (Direct supervision of medical student elective in

Diagnostic Hematopathology)

26) Colvin JH, Lamerson CL, Cualing H, Mutasim DF. Cutaneous

lymphoplasmacytoid lymphoma (immunocytoma) with Waldenstrom's

macroglobulinemia mimicking rosacea.

J Am Acad Dermatol. 2003 Dec;49(6):1159-62.

27) Breneman DL, Raju US, Breneman JC, Steele PE, McFadden DW, Cualing HD,

Nussbaum MS, Swerdlow SH.Reply to Letters to the Editor: Lymph node

grading for staging of mycosis fungoides may benefit from examination

of multiple excised lymph nodes. J Am Acad Dermatol. 2004 vol51:Sept 2004,

483-484.

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28) Connie Keehn*, Cualing H., Marginal Zone Lymphoma with a Dual Cutaneous

and Leukemic Presentation and an Aberrant MyeloidMonocytic Phenotype.

Journal of Cutaneous Pathology

Volume 33: 6, 236-241, March 2006.

29) Rezania D*, Cualing H, Ayala E. Diagnosis, Management, And The Role Of

Hematopoietic Stem Cell Transplantation in Aggressive Peripheral T Cell

Neoplasms Cancer Control Journal, vol 14, no.2, p 151, April 2007.

30) Rezania D*, Cualing H. Sokol L. Aggressive Peripheral T cell Neoplasms and

subtypes with high predilection in the Skin. Cancer Control Journal, vol 14, no.2,

p 116, April 2007.

31) Droc C*, Cualing H., Kadin M. The Need for an Improved Classification For

Therapy of CD30 + lymphomas. Cancer Control Journal, vol 14, no.2, p 124,

April 2007.

32) Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y, Liang C,

Jung JU, Cheng JQ, Mulé JJ, Pledger WJ, Wang HG. Bif-1 interacts with Beclin

1 through UVRAG and regulates autophagy and tumorigenesis. Nature Cell Biol.

2007 Sep 23;

33) Khalil F*, Heekin J, Lili Miles, Cualing H. The rate and morphometric pattern

of bone marrow recovery post-myelosuppressive therapy for acute leukemia: a

quantitative study- Archives of Pathology and Lab Medicine, Vol. 131, No. 8,

pp. 1281–1289, Aug 2007

34) *Cualing HD,Moscinski LC, Zhong E. “Virtual Flow Cytometry” of

Immunostained Lymphocytes on Microscopic Tissue Slides, Clinical Cytometry

part B, Volume 72B, Issue 1 , Pages 63 - 76 Jan 15, 2007.

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http://www3.interscience.wiley.com/cgi-bin/jissue/114026011

35) Alekshun TJ, Rezania D, Ayala E, Cualing H, Sokol L.Skeletal muscle

peripheral T-cell lymphoma. J Clin Oncol. 2008 Jan 20;26(3):501-3. IF:

13.598 PMID: 18202425

36) J Pidala, Cualing H, Pinilla J. Acute basophilic leukemia arising from chronic

myelogenous leukemia with development of t(7;8)(q34, q13) Cancer Genet

Cytogenet. 2008 Apr 1;182 (1):46-9.

37) Raychaudhuri J, Cualing H, Haider K, Kharfan-Dabaja MA.Granulocytic

sarcoma and chronic lymphocytic leukemia of the gastrointestinal tract after

allogeneic hematopoietic cell transplantation mimicking graft-versus-host

disease. Leuk Lymphoma. 2008 Feb;49(2):350-2. IF: 1.559 PMID: 18231925

38) Calder K, Khalil F, Schlauder S, Cualing H, Morgan M. Immunohistochemical

expression of survivin in cutaneous sebaceous lesions. Am J Dermatopathol.

2008 Dec;30(6):545-548. Pubmedid: 19033926.

39) Condarco T, Sagatys E, Prakash A, Rezania D, Cualing H. Primary cutaneous B-

cell lymphoma in a child. Fetal Pediatr Pathol. 2008 Dec;27(4):206-214.

Pubmedid: 18800263.

40) Bernal S, Speak J, Stahel R, Elias A, Mabry M, Cualing H. Small cell carcinoma

antigens. In: Rosen S, Mulshine J, Cuttita F, Abrams P, eds. Biology in lung

cancer: diagnosis and treatment. New York: Marcel Dekker Inc., 1988:213-35:

Book Chapter

41) Cualing H . Pathology of the Spleen. In Handbook of Hematologic Pathology,

Schumacher H, Stass S. Eds. 53-73, Marcel Dekker, Inc., New York, April

2000.: Book Chapter

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42) Mojdeh Naghashpour, Hernani Cualing* Splenomegaly with sea-blue

histiocytosis, dyslipidemia, and nephropathy in a patient with lecithin-cholesterol

acyltransferase deficiency: a clinicopathologic correlation, in press 2009

Metabolism Clinical and Experimental

43) Mojdeh Naghashpour, MD, PhD; Hernani D Cualing, MD; Margaret Szabunio,

MD;

Marilyn M Bui, MD, PhD Hyaline-Vascular Castleman Disease: A Rare Cause of Solitary

Subcutaneous Soft Tissue, in press, 2009 The American Journal of Dermatopathology

Manuscript Number: AJD-D-09-00143 *

* senior/corresponding author

Ongoing Research mentorship projects for fellows 2007 as topics in the monthly research and

planning meeting Hematopathology Mentorship:

Rezania D, Belongie I, Messina J, Cualing H, Glass F. Angioimmunoblastic T cell lymphoma

in skin- manuscript submitted for Archives of Dermatology

44) *Elizabeth Sagatys, MD, Lynn Moscinski, MD, Sophie Dessureault, MD,

Eduardo Sotomayor, MD and Hernani Cualing, MD Analysis of T-cell

Subpopulations in the Lymph Nodes of Patients with Mantle Cell Lymphoma.

Submitted to 49th ASH Annual Meeting and Exposition, Atlanta GA, Dec 8-11,

2007.

45) Iriana Belongie, Jane Messina, Frank Glass, Hernani Cualing. An unusual

lymphoma evolving from CD8+ epidermotropic CTCL, 44th

Annual Meeting,October 18-21, 2007 The American Society of

Dermatopathology, Baltimore Maryland USA.

46) *Dorna Rezania, MD, Elizabeth Sagatys, MD, Marshall E. Kadin, MD, Frank

Glass, MD, Hernani Cualing, MD. CLA and TRAF-1 are Useful in

Differentiating Lymphomatoid Papulosis, Cutaneous ALCL and Systemic

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ALCL, H. Lee Moffitt Cancer Center and Research Institute1, Department of

Pathology, The University of South Florida College of Medicine, Tampa, FL and

Roger Williams Medical Center, Providence RI. Poster to be submitted to

USCAP 2009

47) *Tina Yu, Cualing H, Sagatys E, Rezania D, Moscinski L. Hematodermic tumor

and monocytic sarcoma: Differential immunostaining for USCAP meeting,

presented in March 2008 IAP Denver Meeting.

48) *Sagatys, E., H Cualing , E Zhong and L Moscinski. Automated Determination

of Bone Marrow Cellularity presented in IAP. For submission to Cytometry part

B.

49) *Sagatys E, Cualing H , Rezania D, Naghashpour M, Shaheen G, Moscinski L,

CD71 (Transferrin Receptor) Expression in Precursor and Mature B- and T-cell

lymphomas Recognized by REAL/WHO Classification

50) Cualing H, Sagatys E, Naghashpour M, Smith R. Macrosplenomegaly In AIDS.

Manuscript for Archives of Pathology and Lab Medicine

51) * Yu T, Calder K, Moscinski L, Sokol L, Morgan M, Cualing H. Differential

expression of myelomonocytic Markers in Hematodermic Neoplasm and Acute

Monocytic Leukemia.

52) Niessen Melissa, Blanck George, Cualing Hernani. Thymic dysmorphogenesis

and dysfunction in head trauma patients using molecular and

immunohistochemical markers. Dept of Molecular Medicine Clinical Study.

53) Rezania D, Belongie I, Messina J, Cualing H, Glass F. Angioimmunoblastic T

cell lymphoma in skin- manuscript submitted for Archives of Dermatology

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Doc Hernani Cualing CV

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