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DNA RNA Protein Nucleotides DNA structure DNA Replication Transcription Eukaryotic modification Translation Mutations DNA Repair
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DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

May 26, 2020

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Page 1: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

DNA RNA Protein• Nucleotides• DNA structure• DNA Replication• Transcription• Eukaryotic

modification• Translation• Mutations• DNA Repair

Page 2: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

Nucleotides

Page 3: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

DNA structure

Page 4: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

DNA structure

Implications of Structure

DNA replicationGenetic Information stored in DNA molecule

Page 5: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

DNA Replication• DNA Polymerase III• DNA Polymerase I• Telomerase

Page 6: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

Proofreading

• Error rate of DNA synthesis

• Proofreading • Base Pairing rules

Page 7: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

Eukaryotic Genes

Page 8: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

Transcription

• sense strand (genetic code) • Anti-sense strand (template)

Page 9: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

Transcription

Eukaryotic modification

Page 10: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

Genetic Code

Page 11: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

Translation

Page 12: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

Mutations

Page 13: DNA RNA Proteinguralnl/441DNARNAprotein.pdf · called nucleotides Each nucleotide is composed at phosphorus (al. a Sugar and a base 'd' A nucleotide. (in 0 OH (A) OH W) FIGURE 8.7

DNA Repair