May 2009
Ma
y 2
009
Ma
y 2
009
About Dishman
Business units
Chemistry capabilities
High potency services
Analytical capabilities
Customer service
Why Dishman
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
About Dishman
Mission statement
Key facts
Locations
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Mission statement
Dishman group continually invests in the global pharmaceutical industry, ensuring Dishman’s business can provide pharmaceutical customers with high-value, high-quality products and services today and in the future.
Our focus is to add value to the global pharmaceutical industry by serving as a reliable partner.
Our business is successful only when our customers are successful
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Dishman group key facts
• Established in 1983
• Public company quoted on BSE
• US $200 M turnover company
• Year on year growth more than 30% since 2004
• More than 1,000 technical staff
• Global presence – manufacturing sites in Europe (5), India (2), China, Saudi Arabia
• Successful audit history
• ISO 9001:2000, ISO 14001:2004, OHSAS-18001:2007
• FDA inspected, May 2006
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Locations
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Jay R. Vyas, Managing Director
“I saw the need for a company that could provide high
quality, high value products and services and be a good,
reliable partner to pharmaceutical companies
worldwide”
“Having a competitive cost base and efficient operations
is important, but what’s really key is the quality of our
people, the service they provide, and the value they
offer to our pharmaceutical customers.”
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Business units
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Business units
Dishman Group
DishmanDisinfectants
DishmanVitamins & Chemicals
DishmanContract Research and Manufacturing Services (CRAMS)
Carbogen Amcis
DishmanSpecialty
Chemicals
Dishman Pharma Services
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Dishman specialty chemicals
• Manufacture and supply of quaternary compounds (Quats)
• Extensive product range including ammonium and phosphonium high purity solid Quats, phosphoranes and wittig reagents
• Applications as phase transfer catalysts, personal care ingredients, fine chemicals, pharma intermediates and disinfectants
• Dedicated facilities – Naroda, India
• A number of products made under GMP manufacturing
• Maintain local product stocks
• Significant expertise in custom manufacturing of Quats and fine chemicals
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Dishman specialty chemicals
• Manufacture of quality active pharmaceutical ingredients (APIs) and intermediates
• Expertise in process optimization and large scale cGMP production
• An offering of over 25 APIs
• Substantial regulatory expertise and support
• Development of DMFs, CTDs for advanced intermediates and final APIs
• Strong technology offering to both the generic and ethical pharmaceutical industry
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Ma
y 2
009
• Established 1948
• Acquired by Dishman in 2007
• Cholesterol and vitamin D products
• Based in Veenendaal (Netherlands)
• cGMP production
• Continuous saponification facility
• Large scale chromatography
Sometimes nature needs a helping hand
Dishman vitamins and chemicals
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Dishman vitamins and chemicals
Cosmetics
• Cholesterol NF and HP (emulsifier)
• Dusoran MD (hair care)
• Dusogel (gelifier for cosmetics)
Technical uses
• Cholesterol NF (liquid crystals)
• Lanolin Alcohol
• Lanolin Fatty Acids
Custom work
• On request
Pharmaceuticals
• Ergocalciferol (vitamin D2)
• Cholecalciferol (vitamin D3)
• Dohyfral (vitamin D3 in oil)
• DHT2
• Calcitriol
• Calcifediol
• Alfacalcidol
• Cholesterol HP
Food/feed
• Cholecalciferol
• Dohyfral
• Cholesterol SF and XG
About Dishman ¦ Chemistry Capabilities ¦ Analytical Capabilities ¦ Customer Service ¦ High Potency ¦ Why DishmanBusiness Units ¦
Ma
y 2
009
Dishman disinfectants
• Antiseptics & disinfectants
• Standardized & stabilized for physical, chemical & microbial properties
• Documented as per regulatory requirements
• Innovative user friendly packs
• Superior over leading brands for MIC
Labsept®HTD (Hexetidine) Labsept®BTC (Benzethonium)
Labsept®OCT (Octenidine) Labsept®CHG (Chlorhexidine)
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
CARBOGEN AMCIS
Research Preclinical Phase I Phase II Phase III Market
Niche scale commercial manufacture
API Supply to support clinical requirements
Process research and development
Highly potent API supply
EARLY STAGEProcess research & rapid
supply of APIs
LATE STAGEProcess development& cGMP manufacture
NICHE COMMERCIALProcess optimisation
FDA audited
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Aarau, SwitzerlandEarly stage
PR & D
cGMP API supply
Neuland, SwitzerlandEarly stage
PR & D
cGMP API supply
CARBOGEN AMCIS
Facilities
Manchester,UK
Early / late stage
PR & D
Intermediates
Bubendorf, SwitzerlandLate stage / commercial
Process development
cGMP API manufacture
Highly potent API
Bavla, India
Late stage / commercial
Highly potent API
Commercial supply
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Contract research and manufacturing services (CRAMS)
Large scale and commercial manufacture
Process optimisation
Process development & scale-up
EARLY STAGEProcess research and API supply to support early phase clinical trials
LATE STAGEProcess development and
cGMP manufacture
COMMERCIAL SUPPLYSecure, value-for-money
supply
About Dishman ¦ Chemistry Capabilities ¦ Analytical Capabilities ¦ Customer Service ¦ High Potency ¦ Why DishmanBusiness Units ¦
Process R&D
API supply to support clinical requirements
Niche scale commercial manufacture
Preclinical Phase I Phase II Phase III Market
Highly potent API supply
CA
RB
OG
EN
AM
CIS
Dis
hm
an
Ma
y 2
009
Aarau Neuland Manchester Bubendorf Naroda Bavla Shanghai
Contract research and manufacturing services
Process research and development
API supply to support early clinical trial requirements
Process optimisation
Niche scale commercial manufacture
Large scale and commercial manufacture of APIs and intermediates
Highly potent API supply
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Contract research and manufacturing services
Process R&D
• Problem solving and safe, efficient scale-up
• Delivery of robust, economic, optimised processes
• 200 R&D staff, 70% higher degree
• 250 fume hoods
• Continuous 3 shifts, 6 day, R&D operations (Bavla)
• Strict IP protection policies
We protect our customers interests as if they were our own
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
R&D lab at Bavla, India
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Contract research and manufacturing services
Kilo, Pilot Scale
• Extensive range of segregated, purpose-built, kilo and pilot scale facilities, for cGMP production of API
• Integral part of R&D centres to facilitate maximum interaction and ensure seamless process transfer from laboratory to plant
• Reactions ranging from 50L to 3000L
• Production from kg to several hundred kg scale
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
cGMP pilot plant, Bavla
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Contract research and manufacturing services
Full scale and commercial supply
• 12 manufacturing plants
• US FDA inspected facilities
• > 1150 m3 cGMP reactor capacity
• Skills and capabilities encompassing all routine chemistries and a wide range of sophisticated modern technologies
• Multi-site, multi-country locations
• Over $40M invested in the last 3 years
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
A cGMP manufacturing plant, Bavla
Dishman offer an unparalleled range of both dedicated and multipurpose facilities for the production of APIs and intermediates
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Dishman China
• Shanghai chemical industrial park• $18M investment
• Production facility operational mid 2009
• 4 segregated suites with capability to interlink• 10 reactors from 2500L to 8000L• Class 100,000 product separation, drying, solids handling• Fully segregated RM and finished API warehousing
• QC capabilities for API product release and sourced RM release
Multiple site risk management for pharmaceutical customers
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Chemical industrial park, Shanghai, China
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Chemistry capabilities
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Chemistry equipment
Standard equipment
• More than 250 hoods available for PR&D
• 250 general purpose reactors (50L-16,000L)
• Temp-range: -80oC to +220oC
• Pressure range: 1mbar to 20bar
• Cryogenic reactors to 2,500L
Special equipment
• High pressure autoclaves up to 9,000L
• Dedicated hydrogenation to 5,000L at 20 bar
• Dedicated ozonolysis to 3,000L, 20kg/hr ozone
• Jet milling / micronisation
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness nits ¦
All facilities follow internationally recognised equipment qualification and change control
procedures
Ma
y 2
009
Chemistry equipment
Chemical laboratory Kilo scale set-up
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Pilot plant, R&D centre at Bavla, India
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Chemistry equipment
Manufacturing, commercial scale equipment
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Chemistry equipment
Filters & filter dryers
• Agitated Nutch & pressure Nutch filters / filter dryers from 0.5-7.5m3
Centrifuge
• 50 centrifuges from 480mm –1440mm diameter (35-350kg capacity)
Rotary dryers
• 30 RVD from 150-5,000L glass -Hastealloy
Jet milling
• 150-200kg / hour
Mechanical mills
• Up to 300kg / hour
Spray drying
• 50 kg / hour feed rate
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
High potency services
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Highly potent API supply
• Offered under the CARBOGEN AMCIS business
• Containment facilities for PR&D, clinical trial and commercial material
• Dedicated analytical labs
• 4 R&D labs
• Kilo plant
• Large scale manufacturing facilities (2009, Bavla)
• Successful FDA PAI of HiPo product February 2008
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Highly potent API supply
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
HiPo laboratories
• 4 category 4 (<1 µg/m3 OEL) laboratories
• Class 10,000 clean room
• Barrier benches
• Pressurized airlocks
• Dedicated clean-down areas
• Fume hoods with HEPA filters
• Solids handling isolator with drying oven
• Laminar-Flow for analytical samples preparation
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
HiPo kilo plant
• Category 4 ( <1 µg/m3 OEL)
• Facility operates over 3 floors
• 160 L GL reactor
• 250 L GL reactor
• 250 L Hast reactor
• 100 L Hast reactor
• Temp -100°C to +160°C, Press.12 bar
• 0.125 m2 Hast. filter dryer in glove box
• Barrier isolator technology for solids handling
(dispensing, loading, unloading)
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
HiPo manufacturing
• Category 3 (1-10 µg/m3 OEL)
• 250 L Gl reactor
• 250 L SS reactor
• 630 L Hast. reactor
• Temp -100°C to +160°C, Pres. to 25 bar
• 0.25 m2 Hast. filter dryer
• Pressurized airlocks on all floors
• La Calhène transfer ports for solids charging
in reactors
• Ventilation segregated
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
HiPo analytical capabilities
• Laminar flow hoods and glove boxes for sample preparation
• NMR
• HPLC (SEC-UV, GPC-MALLS, HPLC-MS)
• Hydrolysis method available to capture polymer-bound impurities for conjugates
• GC (FID, Headspace)
• Titrations
• pH-Measurements
• UV/VIS
• IR (KBr pellet)
• KF-determination
• DSC (only closed pan)
• Heavy metals
• Residue on ignition
• Optical rotation
• RC1
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
HiPo facility in Bavla
• Internal fit out of building underway
• Fully cGMP compliant
• Complimentary to existing Bubendorf facility
• Completion H2 2009
• Up to 1,600 L scale
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Building concept
• Dedicated stand alone facility with dedicated utilities
• Category 3(OEL<10µg/m3) and 4(OEL<1µg/m3)
• 4’300 m2 of operational floor space
• Designed to hold 4 segregated High potency handling cells each with 3 reactors and filter/drying plus larger ‘custom’ cell
• Initially 2 cells will be fitted out each having 1 x 630 L, 1 x 1000 L and 1 x 1600 L and 1.0m2 pressure filter dryer
• Further cells are designed for reactors up to 2500L
• The ‘custom’ cell can take reactors up to 6300 L
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Capability
• Category 3(OEL<10µg/m3) and 4(OEL<1µg/m3)
• Barrier Isolation technology
• Fully cGMP compliant
• Able to handle cytotoxic and cytostatic compounds
• Particle size reduction capability
• 2 x Development Labs
• 1 x QC/Analytical Lab
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Analytical capabilities
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Stability
• ICH stability studies
• Stressing studies
• Photostability studies
• Drug substance
stability
• Drug product
stability
• Degradation profiling
• Method development
• Method validation
• Raw material
• IPC
• API
• Method transfer
• Specification
development
• Release analysis
Control
Analytical services overview
• Structure elucidation
• Physical
characterisation
• Polymorphism
investigation
• DSC, XPRD, FTIR
studies
• Particle sizing
• Impurity profiling
• Impurity identification
• Formulation studies• Solubility profile• Salt screening• Compatibility studies
Characterization
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Analytical equipment
• HPLC (DAD, UV, RI) • Ion chromatography• HPLC-MS • GC (FID, NPD)• GC (Head space) • GC-MS • TLC with scanner
• NMR 400 MHz• FTIR • ICP• CHN• XRD• UV-Spectrophotometers• Polarimetry
• Malvern particle sizer• Microscopy• DSC• Auto titrators• Nephelometer• Refractometer• Wet chemical techniques
Chromatography Spectroscopy Physical
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Customer service
Project management
Technology transfer
Quality, regulatory, SHE
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Project management
Management
Purchasing
Project leader
Chemists
Management
Sales
Project leader
Chemists
Steering committee
Ad hoc communication
Routine reporting, tracking
Routine phone conferencing, technical visits
Open, responsive customer service and project management
Customer Dishman
Direct communication e-mail/phone
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Project management
Raw Material Price + Delivery
• Dedicated project manager assigned
• Customer interactive process
• Clarity of requirements
• Comprehensive, detailed, transparent
• Define detailed outputs, deliverables
• Rigorous, proactive tracking
• Provision of data, documentation as appropriate, formal project review
Enquiry Package
Evaluation
Customer Review
Quotation
Project Initiation
Routine Reporting
Completion + Review
Open, responsive customer service and project management
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Technology transfer
• People• Dedicated teams
• Process• Robust well defined processes• Tech transfer package and master plan• Trialling, piloting and change review• All party sign-off
• Expertise• Proven track record• Substantial, multiple project experience
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Technology transfer – example 1
• European customer requiring contract manufacture of a late lifecycle API
• Tech transfer and process optimisation at Bavla site
• Pilot scale validation batches then 10mt commercial production within 9 months
• Agreed regulatory programme completed and client provided with full technical dossier to enable regulatory filings
• Successful project resulted in client transfer of a further 3 projects into the Dishman group
Main advantages are security of supply and cost competitive commercial manufacture
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Technology transfer – example 2
• US customer, 3 stage process, very high purity
• CARBOGEN AMCIS (Manchester) produced 600 kg
• Bavla scaled the entire process to 1500 kg production
• Now going through final QA hurdles prior to acceptance.
Likely volumes 8 t/pa
• Product launched in Japan, soon to be launched in US & EU
Seamless scale-up within the Dishman group affording,
cost competitive commercial supply
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
• Multinational pharmaceutical company required significant cost of goods reduction to deliver market leading drug product
• Dishman optimised process and built dedicated facility for API production
• Dishman further reduced costs by developing its own routes for the 3 key starting materials
• Overall costs reduced by more than 50%. Routine commercial manufacture ongoing at Bavla Site
Significant cost advantage to customer, simplified and
secure supply chain
Technology transfer – example 3
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Quality and regulatory overview
• Batch release procedure
• Record retention
• Sample retention
• Documentation maintenance
• Internal audits
• Change control
• Annual product reviews
• Manufacturing investigations
• API sampling
• Audit preparation & hosting
• Validation related activities
• Batch release testing
• Chromatographic techniques
• Wet chemical techniques
• Microbiological techniques
• Impurity tracking
• Method validation
• Method transfer
• Result trending
• Specification development
• US Type II DMF
• ASMF
• CEP
• Regulatory responses
• Dossier maintenance
• Annual updates
• eCTD capabilities
QC RAQA
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
SHE overview
• OHSAS 18001 certified
• Safety training programme
• Permit to work system
• Fire prevention &
protection plan
• Emergency and accident
management programme
• Risk assessment & Hazop
studies
• Safety audits
• Occupational health &
hygiene programme
• Work place/ personnel
monitoring
• Doctor, health centre
• Periodical health check
• ISO 14001 certified
• Environment and social
audits
• Waste management
programme
• Environmental laboratory
Health EnvironmentSafety
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
Why is Dishman the partner for you?
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Ma
y 2
009
People
Our biggest asset is our people:
• Well educated and experienced staff
• Depth and breadth of chemistry and industry experience
• Expert resources not hired hands
Dr Himani Dhotre
V.P. SCIENTIFIC PROJECT COORDINATION
DIRECTOR TECHNOLOGY TRANSFER
Dr Henk Pluim
Dr Denish ShahGENERAL MANAGER
R&DPRESIDENT
QA/QC/RA/ADL
Alan Barnes
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Dr Ravi RavalGENERAL MANAGER
PILOT PLANT
Ma
y 2
009
Why Dishman?
Partnership
• A dynamic, global partner offering a continuum of services
• Open to new ideas, new solutions, new ways of doing business
Customer Service• A relationship driven business model • Transparency
Adding Value• Commitment to deliver cost competitive, technical excellence• Our business is successful only when our customers are successful
About Dishman ¦ Chemistry capabilities ¦ Analytical capabilities ¦ Customer service ¦High potency ¦ Why DishmanBusiness units ¦
Reliability • Technical and manufacturing excellence in multiple-country locations • Unparalleled range of physical assets, high quality infrastructure
Quality • People• Recognised best practice in systems, procedures and processes
Customer Service• A relationship driven business model • Transparency
Adding Value• Commitment to deliver cost competitive, technical excellence• Our business is successful only when our customers are successful
Reliability • Technical and manufacturing excellence in multiple-country locations • Unparalleled range of physical assets, high quality infrastructure
Quality • People• Recognised best practice in systems, procedures and processes