12/13/12 1 2012 ' BMMB 597D: Analyzing Next Genera=on Sequencing Data Week 15, Lecture 30 István Albert Biochemistry and Molecular Biology and Bioinforma=cs Consul=ng Center Penn State Discussion on the project • Some observa=ons on the project • What went well and what went wrong • Assembly is not well defined ' small changes in hash sizes ! different results Assembly on forward strand Assembly on reverse strand