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Diabetes Technology Update Presented by Diane Caro RN BSN CDE Clinical Nurse IV Patient Health Education UC Irvine Health 1
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Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

May 27, 2020

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Page 1: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Diabetes Technology Update

Presented by Diane Caro RN BSN CDEClinical Nurse IV

Patient Health EducationUC Irvine Health

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Page 2: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Objectives

1. Cite two resources where the ADA’s “2019 Standards of Medical Care in Diabetes” section on Diabetes Technology can be viewed by health care professionals.

2. State 3 unique advantages and 3 potential drawbacks of the different insulin pumps available in the U.S.

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The learner will be able to-

Page 3: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

3. Explain the basics of Basal IQ Technology used in the Tandem t:slim X2 insulin pump.

4. Explain the basics of SmartGuard Technology used in the Medtronic MiniMed 670G insulin pump.

5. Describe a few differences between the OmniPod System and the new OmniPod DASH System.

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Page 4: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

6. Explain the difference between an intermittently scanning CGM and real-time CGM.

7. Explain the difference between Sensor Glucose and Blood Glucose readings.

8. Explain why ongoing education is important for persons with diabetes using an insulin pump and/or CGM.

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Page 5: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

2019 Standards of Medical Care in Diabetes

Published by American Diabetes Association (ADA)

An evidence-based document

Provides up-to-date recommendations, treatment goals and best practices for improving health outcomes in patients with diabetes

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Page 6: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

The complexity and rapid change of available diabetes technology can be a barrier to patient

and provider implementation

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Page 7: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

2019 is the first time the ADA added a dedicated section on diabetes technology to the

“Standards of Medical Care in Diabetes”

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Diabetes Care 2019;42(Suppl. 1):S71–S80 | https://doi.org/10.2337/dc19-S007

Page 8: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

A—Clear evidence from well-conducted, generalizable randomized controlled trials that are adequately powered

B—Supportive evidence from well-conducted cohort studies

C—Supportive evidence from poorly controlled or uncontrolled studies

E—Expert consensus or clinical experience

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Diabetes Care 2019 Jan; 42(Supplement 1): S1-S2.https://doi.org/10.2337/dc19-Sint01

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Insulin Pump Recommendations

Most adults, children, and adolescents with Type 1 Diabetes should be treated with intensive insulin therapy with either multiple daily injections or an insulin pump. AInsulin pump therapy may be considered as an option for all children

and adolescents, especially in children under 7 years of age. C Individuals with diabetes who have been successfully using continuous

subcutaneous insulin infusion should have continued access across third-party payers. E

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Page 10: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Continuous Glucose Monitors Recommendations

. Sensor-augmented pump therapy may be considered for children, adolescents, and adults to improve glycemic control without an increase in hypoglycemia or severe hypoglycemia. Benefits correlate with adherence to ongoing use of the device. A

When prescribing continuous glucose monitoring, robust diabetes education, training, and support are required for optimal continuous glucose monitor implementation and ongoing use. E

People who have been successfully using continuous glucose monitors should have continued access across third-party payers. E

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Page 11: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Real-time Continuous Glucose Monitor Use in Youth Recommendations

Real-time continuous glucose monitoring should be considered in children and adolescents with type 1 diabetes, whether using multiple daily injections or continuous subcutaneous insulin infusion, as an additional tool to help improve glucose control and reduce the risk of hypoglycemia. Benefits of continuous glucose monitoring correlate with adherence to ongoing use of the device. B

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Page 12: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Real-time Continuous Glucose Monitor Use in Adults Recommendations

When used properly, real-time continuous glucose monitoring in conjunction with intensive insulin regimens is a useful tool to lower A1C in adults with type 1 diabetes who are not meeting glycemic targets. A

Real-time continuous glucose monitoring may be a useful tool in those with hypoglycemia unawareness and/or frequent hypoglycemic episodes. B

Real-time continuous glucose monitoring should be used as close to daily as

possible for maximal benefit. A

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Page 13: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Real-time continuous glucose monitoring may be used effectively to improve A1C levels and neonatal outcomes in pregnant women with type 1 diabetes. B

Sensor-augmented pump therapy with automatic low-glucose suspend may be considered for adults with type 1 diabetes at high risk of hypoglycemia to prevent episodes of hypoglycemia and reduce their severity. B

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Page 14: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Intermittently Scanned Continuous Glucose Monitor Use Recommendation

Intermittently scanned continuous glucose monitor use may be considered as a substitute for self-monitoring of blood glucose in adults with diabetes requiring frequent glucose testing. C

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Page 15: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

AUTOMATED INSULIN DELIVERY Recommendation

Automated insulin delivery systems may be considered in children (7 years and older) and adults with type 1 diabetes to improve glycemic control. B

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Page 16: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Where to find these recommendations?

professional.diabetes.org website

ADA Standards of Medical Care App- (This app is only available on the App Store for iOS devices.)

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Page 17: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Question

What type of insulin is used in an insulin pump?

A. Regular insulin

B. Rapid acting insulin

C. Long acting insulin

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Page 18: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Answer

Rapid acting insulin

Humalog, Novolog or Apidra

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Page 19: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

The Basics of Insulin Pump Therapy

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Basal vs. Bolus

Infusion sets

Infusion site care

CSII

Prevention of DKA

Advanced Carb Counting

Troubleshooting

Prevention of hypoglycemia

Pump setting adjustments

Page 20: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Education and Training

Analysis of the MAUDE database suggested that the majority of AEs relate to human factors/user error rather than to technical pump malfunction per se and that preventable AEs may occur more commonly in nonspecialized practices.

Diabetes Care 2015 Apr; 38(4): 716-722.

https://doi.org/10.2337/dc15-0168

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Rational strategies for reducing AEs caused by user error include the following:

Appropriate selection of candidates for pump therapy

Providing those beginning pump therapy with appropriate (and ongoing) education and support

Ensuring that health care professionals supporting pump users are themselves well trained and supported

Ensuring that teams supporting pump users contain a critical mass of members with the necessary skill mix (medical, nursing, dietetics, diabetes educators)

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Page 22: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

MiniMed 670G System

medtronicdiabetes.com

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Page 23: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

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Reservoirs

Holds up to 300 units of insulin

Page 24: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Insulin Pumps Update

Medtronic- 670G system offers SmartGuard technology which provides two levels of automated insulin delivery

1. AUTO MODE

2. SUSPEND BEFORE LOW

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Page 25: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

MiniMed 670G system

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Auto Mode: Automatically increases or decreases basal insulin delivery based upon

CGM values. MUST still administer boluses for food

Suspend Before Low: Stops insulin up to 30 minutes before reaching your preset low limits.

Automatically restarts insulin when your levels recover without bothersome alerts.

Page 26: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

t:slim X2

tandemdiabetes.com

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Page 27: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

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t:simulator™ App

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t:slim cartridge

Holds up to 300 units of insulin

Micro delivery technology

Page 29: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

t:slim x2 insulin pump

Large color touchscreen

Rechargeable battery

Bluetooth wireless technology

Updatable software

May be integrated with the Dexcom G6

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Basal IQ Technology

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Page 32: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

OmniPod

myomnipod.com

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Holds up to 200 units of insulin& Up to 72 hours of insulin delivery

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The PodThe Pod is a small, waterproof device that you fill with insulin and

wear directly on your body.The Pod includes a small, flexible cannula that inserts

automatically with the push of a button.The Pod communicates wirelessly with the Personal Diabetes

Manager (PDM) to program insulin delivery.

Page 35: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

OmniPod DASH System

-Touch-screen bluetooth enabled PDM (personal diabetes manager) display-Calorie King Food Library-Multiple Mobile Apps

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Page 36: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Device Qualities Consideration

Insulin volume Does the pump hold enough to last the patient 2-3 days? Are basal rate

increments small enough?

Screen legibility Can the patient read all on-screen text?

Alarm and alert recognition Can the user hear or feel them?

Water-proof Is it needed by the user?

Download capability

Is the software easy for the patient to download and review? Does the

download data provide cloud technology to allow the provider to access the

data?

Continuous glucose monitor (CGM)

data

Is it linked with CGM? Does it automatically respond to CGM data and is that

a desired component?

Interface with point-in-time blood

glucose meters Does the meter communicate directly with the insulin pump?

Remote control capabilities Is it desired/needed by the user or caregiver?

Bolus calculation parameters Are the dosage ranges, insulin-to-carbohydrate ratios, correction factors, and

insulin-on-board features adequate?

Infusion device compatibility Which options are available? Are they suited to the needs of the patient?

Complexity of user programming Is the menu layout simple? How many button presses are needed for basic

programming?

Look and feel of the device Size, weight, color, and wearing options (clips, cases) desirable for patient?

Special alerts and reminders Are site change, missed bolus, and customizable reminders and alerts

When a list of covered pump models is determined, the following qualities should be considered:

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Page 37: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

A CGM sensor measures the glucose in what body fluid?

A. Interstitial fluid

B. Capillary blood

C. Intravascular fluid

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Page 38: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

What is a CGM?

A CGM works through a tiny sensor inserted under your skin, usually on your belly or arm. The sensor measures your interstitial glucose level, which is the glucose found in the fluid between the cells. The sensor tests glucose every few minutes. A transmitter wirelessly sends the information to a monitor.

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Check out :Anatomy of a CGM sensor- Diabetes Forecast, May 2014

Page 39: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

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This graph shows that the patients blood sugars are in the target range.

Page 40: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

unnoticed high

unnoticed low

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Page 41: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Fingerstick is like a still photograph

&

CGM is like a motion picture or movie

PHOTOGRAPH

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Page 42: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

VIDEO

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Page 45: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

If the CGM value does not match how you feel:

WHEN IN DOUBT, GET YOUR METER OUT!

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Page 46: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Some Features of CGM systems

System includes a subcutaneous sensor and transmitter

Wireless system between transmitter and receiver

Waterproof sensors/transmitters (receiver/display not waterproof)

Multiple on-screen trend graphs

Direction and rate of change arrows

Mechanical device used to insert sensors

Warm up period (No Data) at beginning of sensor session

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Page 47: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Freestyle Libre 14 Day System

-Intermittently scanned CGM-No alerts or alarms

-Accurate for insulin dosing-One hour warm up

-LibreLink app now available-Only worn on back of upper arm

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Page 49: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Guardian Sensor 3 CGM-Integrates with the

MiniMed 670G & 630G OR

as part of the Guardian Connect CGM System

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Page 50: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Guardian 3 Sensor and One-press inserter

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Page 51: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

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gray charger for transmitter

Guardian connect transmitter

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Page 53: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Guardian Sensor 3

Warm up 2 hours

Calibration within 2 hours, within 6 hours , then every 12 hours

Can be worn up to 7 days

Bluetooth transmitter - Rechargeable for a year or more

FDA to be worn either on the abdomen or back of the arm

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Page 54: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

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DEXCOM G6 CGM

Page 55: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

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May use receiver or phone or both as display device.

2 hour sensor warm upNo calibrations

10 day sensor sessions

Page 56: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

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Single use sensor inserter

Page 57: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Inserting sensor

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Page 58: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Sensor pod

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Page 59: Diabetes Technology Update 2 - UC Irvine Health Resource/Diabetes Workshop/Diabetes...ADA’s grading system uses A, B, C, or E to show the evidence level that supports each recommendation.

Inserting transmitter

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Designed to be the first and only CGM with an implantable

sensor that lasts up to 90 days.

The Eversense Long Term CGM system

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Thank You

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