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Endocrine and Metabolic Disorders
21
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Page 1: Diabetes

Endocrine and

Metabolic Disorders

Page 2: Diabetes

Types of Diabetes Type 1- Insulin deficient, juvenile diabetes

Page 3: Diabetes

Types of Diabetes Type 2- insulin resistance; adult onset;

Page 4: Diabetes

Types of Diabetes Gestational diabetes- BMI >30, history of GDM

Page 5: Diabetes

Diagnosis of DiabetesA1C- measures your average blood glucose for the past 2

to 3 months.

Page 6: Diabetes

Diagnosis of Diabetes Fasting Plasma Glucose (FPG)

Page 7: Diabetes

Diagnosis of Diabetes Oral Glucose Tolerance Test (also called the OGTT)

Page 8: Diabetes

Diagnosis of Diabetes Random (also called Casual) Plasma Glucose Test

Blood glucose of greater than or equal to

200 mg/dl

Page 9: Diabetes

Diagnosis of Diabetes GDM- new recommendation for OGT 24-28 weeks

1st- 50 g OGT non-fasting measure glucose 1hour after

and if its greater than 140, you have to proceed to step

2.

Step 2- different day for fasting. 100 g OGT and will

wait 3 hours. If after 3 hours the BG is greater than 140

then you’re diagnose with GDM.

Page 10: Diabetes

Goals for all diabetes Maintain Blood glucose level

Consistent carbohydrate intake

Monitor Blood glucose

Planned exercise

Endurance Athletes: 120-180 mg/dl is the blood glucose

range guideline during activity

Page 11: Diabetes

Glycemic Index GI of a food based on the blood glucose response

compared to a reference food

High GI Foods - Glucose, bread, potatoes, breakfast

cereal, sports drinks

Medium GI Foods- Sucrose, soft drinks, oats, tropical

fruits

Low GI Foods- Fructose, milk, yogurt, ice cream

lentils, pasta, nuts, apples, oranges

Page 12: Diabetes

Food List Starch Group (measured after cooking)

1 slice of bread

1/4 large bagel1/2 hamburger bun, hot-dog bun, pita bread, English muffin1/3 cup rice, pasta, millet, couscous1/2 cup beans

1/2 cup starchy vegetable

1/2 cup oatmeal, kasha, grits, bulgur

1 small tortilla (flour or corn, 6 inch size)

6 saltine crackers3 graham cracker squares3 cups popcorn

Page 13: Diabetes

Food List & Carb countingFruit Group

1 small apple, orange, peach, pear, or nectarine 1 small banana 1/2 grapefruit

1/2 cup unsweetened applesauce 3/4 cup fresh pineapple chunks, blueberries, or blackberries 17 grapes 1 cup cantaloupe, honeydew, or papaya

1 large kiwi2 tablespoons raisins1/2 cup orange juice, apple juice, or grapefruit juice

Page 14: Diabetes

Food List & Carb counting Milk Group

1 cup of milk

1 cup of soy milk

1 cup of buttermilk

2/3 cup of plain yogurt

2/3 cup of aspartame sweetened yogurt

Page 15: Diabetes

Medication Meglitinieds (Glucotrol), Sulfonylureas: Increase

insulin release from the pancreas

Metformin: Enhace insulin reaction

Thiazolidinediones- insulin sensitizers

Starch blockers (Acarbose) delaying carbohydrate

absorption

Glucagon like peptide- enhance insulin secretion

Amylin Agonist

Page 16: Diabetes

Dawn Phenomenon &

Somogyi effect

a surge of hormones that the body produces daily

around 4:00 a.m. to 5:00 a.m.

two phenomena of morning hyperglycaemia

Dawn phenomenon occurs when endogenous insulin

secretion decrease

Somogyi effect is present in the case of excessive

amounts of exogenous insulin.

Page 17: Diabetes

Complications of uncontrolled

diabetes Diabetic ketoacidosis (DKA)- hyperglycemia

Signs

nausea and vomiting

stomach pain

dehydration

fruity breath odor

rapid breathing

Treatment

Insulin, rehydration

Page 18: Diabetes

Complications of uncontrolled

diabetes Acute Hypoglycemia- lack of insulin

Symptoms Shaking, sweating, rapid heartbeat Change in vision Hunger Headache Sudden moodiness

Treatment 15 g CHO Check your blood sugar again after 10-15 minutes. Repeat a dose of fast-acting carbohydrates if the sugar is

still low <70 mg/dl. give another 15 g Carb

Page 19: Diabetes

Complications of uncontrolled

diabetes Long Term

Page 20: Diabetes

Types of Insulin

Fast-acting insulin

Rapid Acting Insulin Analogs

Regular Human Insulin (Insulin Aspart, insulin Lyspro, Insulin Glulisine)

ONSET PEAK DURATION

5-15 Minutes 1-2 hours 4-6 hours

ONSET PEAK DURATION

30-60 minutes 2-4 hours 6-8 hours

Page 21: Diabetes

Types of Insulin Intermediate-acting insulin

NPH Human Insulin, Pre-Mixed Insulin

Long-acting insulin Insulin Glargine, Insulin Detemir

ONSET PEAK DURATION

1-2 hours 4-6 hours 12 hours

ONSET PEAK DURATION

1 1/2 -2 hours No peak 24 hours