Department of Bioch School of Life Sci University of M 10. Number of teaching po Professors/Asst. Profes San Professor Associate Professors Asst. Professors Others 1 Name of the Departme 2 Year of establishment 3 Is the Department par School/Faculty of the u 4 Names of programmes PG, M.Phil., Ph.D., Int Masters; Integrated Ph D.Litt., etc.) 5 Interdisciplinary prog departments involved 6 Courses in collaboratio universities, industries institutions, etc. 7 Details of programmes discontinued, if any, w 8 Examination System: A Semester/ Trimester/C Credit System 9 Participation of the de the courses offered by departments NAAC Reaccreditation - Evalua School of Li Department of Bi 268 hemistry iences Madras osts sanctioned, filled and actual (Professor ssors/others) nctioned Filled Actual (including C 1 - 2 2 1 1 4 3 3 - - - ent Biochemistry 1933 rt of a university? Yes, School of Life Sciences s offered (UG, ntegrated Ph.D., D.Sc., · M.Sc Advanced Biochem · M.Sc Bioinformatics · M.Phil Biochemistry · PhD (Biochemistry) grammes and · UGC-CPEPA (Biochem Botany and Biotechnolo · UPE II “Drug Developm Medical Biochemistry, E ion with other s, foreign Nil s with reasons Nil Annual/ Choice Based Choice Based Credit System epartment in other · PG diploma in molecul and stem cell technology · PG diploma in Immunote ative Report ife Sciences iochemistry rs/Associate CAS & MPS) mistry mistry, Zoology, ogy), ment” (Zoology, Endocrinology) lar cell biology echnology
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Department of BiochemistrySchool of Life Sciences
University of Madras
10. Number of teaching posts sanctioned, filled and actual
Professors/Asst. Professors/others) Sanctioned
Professor Associate Professors Asst. Professors Others
1 Name of the Department 2 Year of establishment
3 Is the Department part of a School/Faculty of the university?
16. Research thrust areas as recognized by major funding agencies
a) Cell signaling in cancer, cardiovascular diseases, gastro-intestinal and respiratory infections
b) Glycobiology and Glycotechnology- Structure – function relationships of epithelial mucins, regulation of their expression in cancer & gastrointestinal diseases
c) Molecular Cardiology-Cardiac hypertrophy, ischemic-reperfusion injury, atherosclerosis
e) Diabetetology-antidiabetic therapy f) Drug development from medicinal plants
17. Number of faculty with ongoing projects from a) national b) international
funding agencies and c) Total grants received. Give the names of the funding
agencies, project title and grants received project-wise.
Name of faculty Title of Project Funding Agency
Amount Date of sanction and Duration
S.Niranjali Devaraj “Bioactivity based screening of medicinal plants in South India for inflammation-associated cancer”
AYUSH 46 lakhs 2009-2012 extended till 2013 March
S.Niranjali Devaraj Molecular signal interventional approach to improve ovarian maturation and spawning in commercial brooders of P. monodon – studies in alternate regulation of gene expression to initiate the activation of maturation promoting factor (MPF) in shrimps.
DBT 62.39 lakhs
2010-2013
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S.Niranjali Devaraj Screening, isolation and characterization of antiviral compounds from various species of Phyllanthus
UGC CPEPA
6.26 lakhs 2012-2015
S.Niranjali Devaraj Screening, isolation and characterization of antiviral compounds from marine organisms
UGC CPEPA
6.26 lakhs 2012-2015
T.Devaki Cellular and molecular mechanism underlying the anticarcinogenic effect of chrysin in experimentally induced hepatocellular carcinoma
UGC 12 lakhs 2011-2013
T.Devaki Magnetic Nanoparticles for Effective target Drug Delivery of Carvacrol against Liver Carcinogenesis –A Molecular Approach
ICMR adhoc project
21 lakhs 2012-2014
Elangovan.V Design and synthesis of biodegradable nanoparticle for effective delivery siRNA in the heart....Natriuretic Peptide Receptor-C
ICMR 25 lakhs 2012-2015
Subramanian.S “Modulatory effects of resveratrol, a naturally occurring phytoalexin, on the expression of GLUT-4,PI3 kinase, PEPCK, PPARgamma and related key regulatory enzymes in rat L6 skeletal muscle cells”
UGC 10.27 lakhs
2010-2013
Sudhandiran G Fisetin, a bioflavanoid exhibits antileishmanial activity through modulating the ERK and JAK- STAT signaling cascades: A mechanistic approach to combat leishmania survival inside macrophage.
UGC 8.5 lakhs 2010-2013
Sudhandiran G NCNSNT Role of Epigallocatechin-3-gallate as nano chemopreventive agent in lung cancer cells:Elucidation of TGF-� mediated CLIC4/Schnuri signaling cascade.
NCNSNT 7.5 lakhs 2011-2014
Sudhandiran G Critical role of Autophagic pathway in Alzheimer’s disease: Regulating the autophagy through PI3K/Akt/mTOR and Nrf2 signaling cascades
DST 41 lakhs 2011-2014
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Sudhandiran G Protease activated receptors 1 and 2 as a novel therapeutic target in bleomycin-induced experimental pulmonary fibrosis: Enancement of Phase II enzymes by garlic derivatives, Diallyl sulfide and S-allyl cysteine, through Nrf2-Keap1 signaling.
ICMR 17.25 lakhs
2012-2015
Sudhandiran G Screening, isolation and characterization of antiviral compounds from various species of Phyllanthus
UGC CPEPA
6.26 lakhs 2012-2015
Sudhandiran G Screening, isolation and characterization of antiviral compounds from marine organisms
UGC CPEPA
6.26 lakhs 2012-2015
Vanisree AJ Targeting…glioma ICMR 12.08 lakhs 2010-2013 Vanisree AJ Evaluation of neuroprotection by
Noni in rats WNRF 11 lakhs 2011-2013
18. Inter-institutional collaborative projects and associated grants received
a) National collaboration - Collaboration with Dr.B.S.Lakshmi, Centre for Biotechnology, Anna University. Title : Isolation and characterization of anti-diabetic and anti-adipogenic molecules from medicinal plants and evaluation of its mechanistic action using in vitro and db/db mice model Funded by DBT : Rs 42 lakhs, 2012-2015
b) International collaboration – Nil
19. Departmental projects funded by DST-FIST; UGC-SAP/CAS, DPE; DBT,
ICSSR, AICTE, etc.; total grants received.
DST-FIST : 45 lakhs
UGC-SAP: 38 lakhs
UGC-Infrastructure development: 40 lakhs
UGC-CPEPA:24 lakhs (first two years)
UPE I : 14.5 lakhs
UPE II: 37 lakhs (first two years)
20. Research facility / centre with -
· State recognition
· National recognition : Centre with Potential for Excellence in a Particular Area
(CPEPA) : Antiviral compounds from Phyllanthus and marine sources-UGC-
funded
· International recognition : Nil
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21. Special research laboratories sponsored by / created by industry or corporate
bodies - Nil
22. Publications:
* Number of papers published in peer reviewed journals (national / international)
: 146
* Monographs : Nil
* Chapters in Books : Two
* Edited Books : Nil
* Books with ISBN with details of publishers : Nil
* Number listed in International Database (For e.g. Web of Science, Scopus,
Humanities International Complete, Dare Database - International Social
Sciences Directory, EBSCO host, etc.) : Nil
* Citation Index – range / average : 39 to 650 ; Average : 299
* SNIP : Range : 0.877 to 1.389 (2011)
* SJR : Range: 0.414 to 3.673 (2011)
* Impact Factor – range / average : Range : 0.878 to 6.73
* h-index : Range: 3-14 ; Average: 10
23. Details of patents and income generated -
A novel compound useful for the treatment and prevention of ischemic heart disease from the plant, Crataegus oxycantha and aprocess for preparation”- through the University of Madras. “A novel compound useful for the treatment and prevention of athersclerosis from the plant Trigonella foenum-graecum and a process for its preparation”-through the University of Madras
24. Areas of consultancy and income generated -
World Noni Research Foundation project grant : Total 20 lakhs
Avigna Pharmeuticals: Project grant Rs 3.8 lakhs
Income: Nil
25. Faculty selected nationally / internationally to visit other laboratories /
institutions / industries in India and abroad
Dr.G.Sudhandiran, selected to visit Molecular Structural Biology Division at CDRI,
Lucknow and worked on Plasmodium falciparum gene expression
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26. Faculty serving in
S.Niranjali Devaraj: · Member of UGC expert committee in Biochemistry to select
major research project proposals: Feb 2010 ,Oct 2011,Oct 2012 & Feb 2013
· UGC expert committee member to examine proposals received under the scheme of instrumentation maintenance facility
· Member of UGC expert committee to select women scientists for post doctoral
fellowships
· UGC expert to select Indo-US-post doctoral Fellows (2012)
· Expert committee member of UGC-CAS in Life Sciences of the University of Hyderabad (2008-2013)
· Expert committee member of UGC-CAS in Biochemistry of the University
of Calcutta (2008-2013)
· TNPSC- Reviewer of question papers in the subject Biochemistry · Chairman of syllabus committee for revision of syllabus and text books in
Biochemistry for StdXI and XII, appointed by the State Council of Educational Research and Training, Tamilnadu (Sept 2012)
T.Devaki
· UGC nominee of building committee of Dhanraj Baid College of Pharmacy · TNPSC- Setting of question paper in the subject Biochemistry S.Subramanian: TNPSC- Setting of question papers in the subject Biochemistry
G.Sudhandiran : TNPSC- Setting of question papers in the subject Biochemistry
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33. Diversity of students
Name of the Programme
(refer to question no. 4)
% of students from the
same university
% of students from other universities within the
State
% of students from
universities outside the
State
% of students from other countries
M.Sc Advanced Biochemistry
2009-2010 2010-2011 2011-2012 2012-2013
68.42 70.83 85.71 80.95
15.78 12.50 9.52 9.52
15.78 16.66 4.76 4.76
Nil Nil Nil 4.76
M.Sc Bioinformatics
2009-2010 2010-2011 2011-2012 2012-2013
92.30 44.44 15.0 50.0
7.69 27.77 20.0 50.0
Nil 22.22 65.0 Nil
Nil 5.55 Nil Nil
M.Phil Biochemistry
2009-2010: 2010-2011 : 2011-2012 : 2012-2013:
73.68 68.18 55.55 45.0
21.05 22.72 38.88 45.0
5.26 9.09 5.55 10.0
Nil Nil Nil Nil
34. How many students have cleared Civil Services and Defence Services
examinations, NET, SET, GATE and other competitive examinations? Give
details category-wise.
NET: 7 , SET : 1
35. Student progression
Student progression Percentage against enrolled UG to PG NA PG to M.Phil. 10% PG to Ph.D. 22% Ph.D. to Post-Doctoral 40% Employed · Campus selection · Other than campus recruitment
40% -
40% Entrepreneurs
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36. Diversity of staff Percentage of faculty who are graduates of the same university 100% from other universities within the State Nil from universities from other States Nil from universities outside the country Nil
37. Number of faculty who were awarded M.Phil., Ph.D., D.Sc. and D.Litt. during
the assessment period : Nil
38. Present details of departmental infrastructural facilities with regard to
a) Library - ERB Shanmugasundaram Library : 452 books
b) Internet facilities for staff and students - WIFI facility to all students and faculty
c) Total number of class rooms - 03
d) Class rooms with ICT facility - Nil
e) Students’ laboratories - 02
f) Research laboratories - 07
39. List of doctoral, post-doctoral students and Research Associates :
a) from the host institution/university – Ph.D : 29 post-doc: 02
b) from other institutions/universities – Ph.D: 47 + 1 (foreign) post-doc : 02
40. Number of post graduate students getting financial assistance from the
university. - Madras University Free Education Scheme: 2 (2012)
Merit Scholarship : 1 (2012)
Endowment scholarships: 64 (2007-2012)
BC/MBC/SC/ST scholarships : 122 (2007-2012)
41. Was any need assessment exercise undertaken before the development of new
programme(s)? If so, highlight the methodology. NA
42. Does the department obtain feedback from
a. Faculty on curriculum as well as teaching-learning-evaluation? If yes, how
does the department utilize the feedback?
Yes. Feedback received from the faculties is placed before the Departmental
Committee to revise the curriculum.
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b. Students on staff, curriculum and teaching-learning-evaluation and how
does the department utilize the feedback?
Students on staff – every academic year feedback is obtained by the IQAC and
the findings are communicated to the faculty individually every year. The
feedback is taken into account for confirmation/ promotion.
c. Alumni and employers on the programmes offered and how does the
department utilize the feedback?
YES – Representation from Industries are members of the Board of Studies
43. List the distinguished alumni of the department (maximum 10)
· Dr.M.Damodaran D.Sc (Lon),FRIC (Founder)
· Dr.P.S.Sarma (HOD , Former HOD IISc)
· Dr.ERB Shanmugasundaram (HOD, produced 72 PhD scholars)
· Dr.Radha Shanmugasundaram: (Former HOD, Medical Biochemistry, Madras
University)
· Dr L.K.Ramachandran (Former HOD, Osmania University)
44. Give details of student enrichment programmes (special lectures / workshops /
seminar) involving external experts.
S.No Seminar/special lecture/workshop Speakers 1 “Decision to Live or Die. The
Evolution of Cell Death”. 23rd June 2009.
Dr. Chandrima Shaha, Director,NII-New Delhi
2 “Good Riddance to Neurotransmitters: New Insights into the Regulation, and Neuropsychiatric Disorders” , Dec 9, 2007
Professor S. Ramamoorthy, Director, Neuroscience Graduate Program, Department of Neurosciences, Medical University of South Carolina, USA,
3 “Bioinformatics “Oct 23rd , 2007)
Aravind Ramakrishnan of Cognizant Technology Solutions India Pvt Ltd
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4 “Lead Toxicity” gave a popular lecture on lead toxicity, Aug 7, 2007.
Dr. T .Bhooma, Toxicologist in USEPA, Chicago, USA
5 “Health is Wealth”, 28March2011
Dr Kamali Sripal,
6 Promethean curse to tower of Babel…..future of heart care”,29th March 2011
Dr. M.P. Nareshkumar, MS . Mch. FRCS (EDIN). Cardiologist, Harvey Heart Hospital, Chennai
7 “Bioinformatics-opportunities and challenges”29th March 2011
Dr V.Subramanian, Scientist E , CLRI
8 “Statistical Analysis using SPSS”, 2012 March
Dr.R.Ravanan , Associate Professor, Department of Statistics Presidency College
9 “Wound healing in leprosy patients”, 2012, March
Dr.Gunasekaran., Director, King Institute, Chennai
10 “Breast cancer awareness” March 2012
Dr Sridevi, Surgical Oncologist, Cancer Institute
11 “Beta3 integrin-mediated cardioprotective signaling in pressure-overloaded myocardium”,28th Jan 2010
Dr Dhandapani Kuppuswamy, Associate Professor of Medicine, Medical University of South Carolina, USA.
12 “Modern evidence for ancient wisdom on diet and disease”, 2011
Dr.Jairam Vanamala, Director of Bioactives and Probiotics for the Health Laboratory , Department of Food Science and Human Nutrition, Colorado State University, USA
13 “Genomic mutation in guanylyl cyclase-natriuretic peptide receptor A-defines protective role in cardiovascular regulation”,Dec 11,2008
Dr.Kailash N.Pandey,Professor & Vice-Chairof Medical Research,Dept of Physiology,Tulane School of Medicine,USA
45. List the teaching methods adopted by the faculty for different programmes.
The teaching methods include lectures, group discussions, seminars, tutorials and power point presentation.
46. How does the department ensure that programme objectives are constantly met
and learning outcomes are monitored?
By periodical sessional tests, assignment, quiz, tutorials and counseling.
47. Highlight the participation of students and faculty in extension activities.
Students and faculty involve themselves in organizing seminars, workshops,
conferences, clinical diagnostics (free of charge for teaching, non-teaching staff and
students)
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48. Give details of “beyond syllabus scholarly activities” of the department.
Awareness programmes in Cancer, Genetic engineering were conducted by the
Department
Participation and presentations in National conferences
49. State whether the programme/ department is accredited/ graded by other
agencies? If yes, give details.
No
50. Briefly highlight the contributions of the department in generating new
knowledge, basic or applied.
A new post- graduate course: Bioinformatics and Clinical trial management was
started in affiliated colleges .The syllabus was framed by the Department. to provide
students with a theoretical understanding of the issues involved in the design, analysis
and interpretation of clinical trials, besides imparting knowledge on the scientific,
regulatory and ethical aspects in clinical trials. This will help students to meet the
demands of the industry and expand the avenues for job opportunities
Our research is proceeding from the laboratory to the bed-side: Clinical trials are
being done on cancer patients, obesity patients and diabetics.
51. Detail five major Strengths, Weaknesses, Opportunities and Challenges
(SWOC) of the department.
Strengths:
· Strong and established research programmes
· Quality teaching by a majority of the faculty
· Productive in terms of publications
· Strong research potential with proven records of good quality research
· Excellent, teacher-teacher and student-teacher relationship
Weaknesses:
· Shortage of staff
Opportunities:
With available facilities and being a part of the UGC-CPEPA, DST-PURSE and
UGC-UPEII programmes and in view of the scope in the future for being selected
under DBT-BUILDER programme - the Department is poised to become a leader in
this field.
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Challenges:
The decline in the number of students applying for M.Sc Biochemistry is a matter of
concern and we are looking at ways to meet this challenge
Department has made commendable progress in biochemical teaching and research.
However, running 4 programmes with a limited faculty of six is a major challenge
52. Future plans of the department.
The Department has identified Glycobiology, molecular cardiology and cancer
biology as its major research areas and would strive to achieve excellence in these