Department of Biochemistry Research The main areas of research in our Department includes Membrane Biochemistry, Cancer Biology, Neurogerontology, Reproductive Biology etc., We have produced more than 20 PhD students who have got placed as scientist, post doctoral fellows in various leading international institutes in USA, Korea, Sweden. Within the short span time, the Department has grown into a vibrant academic department and research centre in Biochemistry, where we have made great stride in higher education, research and extension activities in the area of specialization. The Department was recognized for DST-FIST Program in the year 2012. The department has generated funds worth five plus crores for Research and Infrastructure from various funding agencies like CSIR, NFMP, DST, DBT, ICMR and UGC etc., To add on to the credentials, more high impact factor publications has been made in well reputed Journals and published many book chapters in the core area of research. The department has hosted many national level conferences and workshops benefiting students.
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Department of Biochemistry - bdu.ac.in · Vishnu Varthini L Selvaraju K, Srinivasan M, Nachiappan V. (2014) ROG1 encodes a (2014) ROG1 encodes a monoacylglycerol lipase in Saccharomyces
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Department of Biochemistry
Research
The main areas of research in our Department includes Membrane Biochemistry, Cancer
Biology, Neurogerontology, Reproductive Biology etc., We have produced more than 20 PhD
students who have got placed as scientist, post doctoral fellows in various leading international
institutes in USA, Korea, Sweden. Within the short span time, the Department has grown into a
vibrant academic department and research centre in Biochemistry, where we have made great stride
in higher education, research and extension activities in the area of specialization. The Department
was recognized for DST-FIST Program in the year 2012. The department has generated funds worth
five plus crores for Research and Infrastructure from various funding agencies like CSIR, NFMP,
DST, DBT, ICMR and UGC etc., To add on to the credentials, more high impact factor publications
has been made in well reputed Journals and published many book chapters in the core area of
research. The department has hosted many national level conferences and workshops benefiting
students.
S. No. Name Reg. No. Fellowship
1. Karthik S 6354 UGC – Project Fellow
2. Sankar R 44356 DST INSPIRE – SRF
3. Mohanraj S 4818 ICMR - JRF
4. Premkumar P 6403 DST – Project Fellow
5. Sivasangari B 4933 DBT – JRF
6. Sathya M 39336 UGC – Project Assistant
7. Karthick C 5195 CSIR – SRF
8. Balamurugan R 33504 UGC – Project Fellow
9. Selvaraju K 22214 CSIR - SRF
10. Varunkumar K 45376
DST – JRF
ICMR - SRF
11. Anusha C 30014 URF – BDU
12. William James 42467 DST – PURSE
13. Sivapraksam 43854 NMPB - JRF
14. Vijayakumar R 42234 NMPB – SRF
CSIR - SRF
15. Lakshmi Priya K 45375 DST – INSPIRE - SRF
16. Arun K 7905 URF – BDU
ICMR - SRF
17. Sridharan J 32851 URF – BDU
18. Periyasamy S 47364 URF – BDU
19. Uma Maheswara Rao D 34407 UGC – RGNF – SRF
20. Saravanan K 34406 DST – SERB – JRF
21. Anantha Lakshmi N 7705 DST – (WOS – A) – PI
22. Mahesh Kumar K 7941 DBT – JRF
23. Palanimuthu DST – Post –Doc
24. Bhanupriya N 45145 DST – INSPIRE – JRF
25. Vennila S 29336 DST – WOS-A – SRF
26. Ravi C 32367 SERB – JRF
27. Roseline M 7868 URF – BDU
28. Nithya G 14727 URF – BDU
29. Subitha M 5486 URF - BDU
30. Prabhu S 25991 DST – PURSE II - JRF
31. Suhadha Parveen 25862 LADY TATA – JRF
32. Roshan 003280 DBT- JRF
Details of Fellowships being availed by the
Research Scholars/Project Staff
Citations
Research & Consultancy Projects
Completed Projects
S.
No.
Principal
Investigator
Project Title Period Funding
Agency
Amount
₹ (in
lakhs) From To
1. Dr. M.
Anusuyadevi
Jayachandran
Does Sirtuin Proteins attenuate
Alzheimer’s disease pathogenesis
by regulating cholesterol
homeostasis? An approach to
understand biochemical concept
behind AD pathology.
2012 2015 DST 23.69
2. Dr. M.
Anusuyadevi
Jayachandran
Do mitochondria dysfunction
provide possible grounds for
Amyloid (Aβ 42) formation
during aging- intervention of
sirtuins in counteracting multiple
stage pathophysiology with
specific reference to AD
2010 2015 DBT 13.80
3. Dr. M.
Anusuyadevi
Jayachandran
Identification of the Intracellular
localization of α, β and γ secretase
and APP cleavage pattern in
young and aged rat brain region:
an understanding towards the
underlying mechanism behind AD
pathology.
2012 2015 UGC 13.48
4. Dr. M.
Anusuyadevi
Jayachandran
Hyperinsulinemia influences
autophagy and mitochondrial
biogenesis: A possible mechanism
of neuronal ageing.
2013 2016 ICMR 50
5. Dr. Vasanthi
Nachiappan
Remodeling of fatty acid in
phosphatidyl choline rat liver as a
model system
2008 2011 UGC 10.89
6. Dr. Vasanthi
Nachiappan
Endoplasmic reticulum (ER)
stress induced autophagy in
Saccharomyces cerevisiae and the
implication in Phospholipid.
2012 2015 CSIR 22.92
7. Dr. Vasanthi
Nachiappan
Characterization of active
principle from Cassia auriculata
as a potential drug for
hyperlipidemia and cardiovascular
disease
2013 2017 NMPB 23.52
8. Dr. C.
Prahalathan
Evaluation of the Effect of Acute
Inflammation on Histone H3
Modifications in Rat Testis and
Its Implications in Testicular
Steroidogenesis
2011 2014 DBT 21.63
9. Dr. C.
Prahalathan
A Study on Proinflammatory
Cytokines Mediated Histone H3
Modifications in R2C Leydig
2011 2014 ICMR 20.15
Cells and Its Implications in
Regulation of Testicular
Steroidogenesis
10. Dr. C.
Prahalathan
Evaluation of the Effect of Acute
Inflammation on Histone H3
Modifications in Rat Pancreas and
Its Implications in Insulin Gene
Transcription
2011 2014 UGC 13.17
11. Dr. C.
Prahalathan
Role of Class II Histone
Deacetylases in Regulation of
Insulin Gene Transcription
2012 2015 DST 16.70
12. Dr. V.
Ravikumar
Nano encapsulation of
Suberoylanilide hydroxamic acid
(SAHA): an attempt to improve
anticancer activity in non-small
cell lung cancer cell lines.
2011 2014 UGC 11.14
13. Dr. V.
Ravikumar
Synergistic Interaction Of The
Histone Deacetylase Inhibitor
With The Proteasome Inhibitor In
Lung Cancer.
2012 2015 DST 22.75
14. Dr. A.
Antony
Joseph
Velanganni
Molecular characterization of
Constitutive and Consensus
miRNA Expression Profiles in
NCI-60 Panel of Human Cancer
Cell Lines
2012 2015 UGC 13.92
15. Dr. A.
Antony
Joseph
Velanganni
Exploration of hTERT gene
inhibition in cervical cancer cells
by nanoencapsulated hTERT-
siRNA
2014 2017 DST-
(WOS-
A)
24.13
16. Dr. A.
Antony
Joseph
Velanganni
RNAi mediated Functional
Analysis of RNA induced
Silencing Complex (RISC) and its
Component AEG-1 that induce
the Expression of Transcription
Factor LSF in Hepatocellular
Carcinoma
2015 2018 DBT 25.00
Ongoing Projects
S.
No.
Principal
Investigator
Project Title Period Funding
Agency
Amount
₹ (in
lakhs)
From To
1. Dr. M.
Anusuyadevi
Jayachandran
Assessment of the effect of aspirin
treatment on neural stem cells and
the regulation of hippocampal
neurogenesis in the adult brain of the
experimental rodents: A non-invasive
attempt for the brain regeneration
2017 2020 SERB 52.00
2. Dr. Vasanthi
Nachiappan
High throughput screening &
molecular analysis of GCR1
transcription factor and its impact on
the binding motif of OPI3 promoter
in Saccharomyces cerevisae
2017 2020 SERB 47.92
3. Dr. C.
Prahalathan
Elucidation of the role of SIRT4 in
testicular steroidogenesis 2018 2021 SERB 38.20
4. Dr. V.
Ravikumar
Investigation on acetylation
dependent activation of Notch
signaling pathway by HDAC
inhibitors - A possible mechanism
for drug resistance and survival upon
HDAC inhibition therapy in NSCLC
cell lines
2016 2019 SERB 28.99
5. Dr. A.
Antony
Joseph
Velanganni
Social Support and Reproductive
Autonomy of Visually Challenged
Women in the Rural Districts of
Tamil Nadu
2017 2019 ICMR-
ICSSR
13.75
Collaborative Projects
S.
No
Agency Period Project Title Budget
(Rs. In
lakhs) From To
1 NMPB 2012 2015 Characerization Of Active Principles From
47. Periyasamy, S., Sathya, M., Karthick, C., Kandasamy, M., Shanmugaapriya, S., Tamilselvan, J.,
Jayachandran, K. S., Anusuyadevi, M. Association studies of specific Cholesterol related genes
(APOE, LPL, and CETP) with Lipid profile and memory function: A correlative study among
Rural and Tribal Population of Dharmapuri District, India. J Alzheimers Dis. 2017 (doi:
10.3233/JAD-170272).
48. Velusamy, T., Panneerselvam, S. A., Purushottam, M., Anusuyadevi, M., Pal, P. K., Jain, S.,
Essa, M. M., Guillemin, J. G., Kandasamy, M. Protective effects of antioxidants on neuronal
dysfunction and plasticity in Huntington’s disease. Oxidative medicine and cellular longevity,
2017.
49. Sankar, R., Rahman, P. K., Varunkumar, K., Anusha, C., Kalaiarasi, A., Shivashangari, K. S.,
&Ravikumar, V. (2017). Facile synthesis of Curcuma longa tuber powder engineered metal nanoparticles for bioimaging applications. Journal of Molecular Structure, 1129, 8-16.
50. Theodore Lemuel Mathuram, Vilwanathan Ravikumar, Lisa M. Reece, Changam Sheela
Sasikumar, Kotturathu Mammen Cherian (2017). Correlative Studies Unravelling the Possible Mechanism of Cell Death in Tideglusib-Treated Human Ovarian Teratocarcinoma-Derived PA-1 Cells. Journal of Environmental Pathology, Toxicology and Oncology, 36(4):321–344.