Brunner & Suddarth’s Textbook of Medical-Surgical Nursing 14 th ed. Chapter 12. (p 225)
Unpleasant sensory and emotional experience
resulting from actual or potential tissue damage.
This definition describes pain as a complex
phenomenon that can impact a person’s psychosocial,
emotional, and physical functioning.
Pain “whatever the experiencing person says it is,
existing whenever she/he says it does”. McCaffery, 1968
It is a subjective experience.
Definition of Pain
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Effects of Pain
• Affect every age, sex, race & socioeconomic class
• The primary reason people seek health care
• Unrelieved pain can affect every system in the body
– This is particularly harmful in patients whose health
is already compromised by age, illness, or injury.
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I. Acute pain
– Recent onset & associated with a specific injury
– have a relatively short duration, resolve with
normal healing.
– Decreases as healing occurs.
– example of acute pain: tissue damage as a result
of surgery, trauma, or burns produces
Types and categories of Pain
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II. Chronic pain
– either due to cancer or noncancer origin
– may resolve within months or persist throughout the
course of a person’s life.
– Constant or intermittent
– persists beyond the expected healing time & seldom be
attributed to a specific cause or injury.
– Poorly defined onset, Difficult to treat (unclear cause).
– examples: peripheral neuropathy from diabetes, back
or neck pain after injury, and osteoarthritis
Types and categories of Pain
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• Some conditions can produce both acute and chronic pain.
– For example, some patients with cancer have continuous chronic pain and also experience acute exacerbations of pain periodically—called breakthrough pain (BTP)—or
• Endure acute pain from repetitive painful procedures during cancer treatment.
Types and categories of Pain
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• According to inferred pathology I. Nociceptive (physiologic) pain refers to the normal
functioning of physiologic systems that leads to the perception of noxious stimuli (tissue injury) as being painful “normal” pain transmission. a. Somatic pain
- Arises from bone, joint, muscle, skin - Described as aching or thrombing pain, Well localized
- E.g., surgical, trauma, wound and burn, labor pain, rheumatoid arthritis
b. Visceral pain: arises from visceral organ ( GIT, Panaceas); e.g., ulcerative colitis crohn’s disease, pancreatitis.
Types and categories of Pain
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II. Neuropathic (pathophysiologic) pain is pathologic and
results from abnormal processing of sensory input by the
nervous system as a result of damage to the peripheral or
CNS or both .
Neuropathic pain may be associated with abnormal
sensations called dysesthesia or pain from normally non-
painful stimuli (allodynia).
– Phantom pain: a result of peripheral nerve damage, post stroke
pain, pain following spinal cord injury
• pain that feels like it's coming from a body part that's no longer there
Types and categories of Pain
Endorphin is a hormone that your body produces to ease pain
and make you feel calm and happy."natural pain killers"
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Patients may have a combination of nociceptive & neuropathic
pain.
For example:
Pain from tumor growth>>> nociceptive pain & if pt
report radiating pain due to pressure against nerve plexus
>>> neuropathic pain
Sickle cell disease pain is usually a combination of nociceptive
pain from the clumping of sickled cells and resulting perfusion
deficits, and neuropathic pain from nerve ischemia.
Types and categories of Pain
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Nociception: the process by which information about tissue damage is conveyed to the CNS.
1) Transduction: the conversion of the energy from a noxious stimulus into electrical energy (nerve impulses) by sensory receptors called nociceptors
2) Transmission: the transmission of these neural signals from the site of transduction (periphery) to the spinal cord and brain
3) Perception: the appreciation of signals arriving in higher structures as pain
4) Modulation: descending inhibitory and facilitory input from the brain that influences (modulates) nociceptive transmission at the level of the spinal cord.
Pain pathway
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What happens during transduction?
• Damaged cells release mediators of inflammation (prostaglandins, substance P, bradykinin, histamine, serotonin, cytokines).
• Nociceptor activation:
• Nociceptors are sensory receptors that are sensitive to tissue trauma or a stimulus .
• Signals from these nociceptors travel along two fiber types:
unmyelinated C-fibers, slowly conducting
myelinated A-delta fibers, rapidly conducting
Pain pathway
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• Clinical implications
– Some analgesics target the inflammatory process
such as NSAIDs inhibit cyclooxygenase (COX), thus
decreasing the synthesis of prostaglandins.
– Other analgesics (antiepileptic drugs, local
anesthetics) block channels, thus inhibiting the
generation of nerve impulses.
What happens during transduction?
Pain pathway
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• Nerve impulses are transmitted to the spinal cord and brain in several phases:
• Periphery to the spinal cord:
• Spinal cord to the brain
– Clinical implications Some analgesics inhibit signals in the dorsal horn (DH).
• For example, opioid analgesics bind to opioid receptors on primary afferent and DH neurons.
What happens during transmission?
Pain pathway
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• Information from some dorsal horn (DH) projection
neurons travels via the thalamus to the
somatosensory cortex, where information about
the location, intensity, and quality of the pain is
identified.
What happens during perception?
Pain pathway
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• Descending pathways
- The reduction of DH transmission by descending inhibitory input from the brain.
• Nerve fibers release inhibitory substances (endogenous opioids, norepinephrine) that bind to receptors inhibit transmission.
• Clinical implications Some analgesics enhance the effects of descending inhibitory input. For example, some antidepressants are used to treat some types of chronic pain.
What happens during modulation?
Pain pathway
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• Assess posture and pain behaviors.
• Ask the patient to describe pain in own words
Factors to consider in pain assessment
– intensity, timing, location ,quality, personal
meaning of pain; aggravating and alleviating
factors; and pain behaviors.
Pain assessment
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Questions to assess pain • Where is the pain located? How long does it last? How
often does it occur? • How would you describe the pain? • What brings the pain on? • What relieves the pain or makes it worse? • What do you think is causing your pain? • What do you fear most about the pain? • What problems does the pain cause you? • Who else have you consulted about the pain? Family
members? • What treatments do you think might help you with
the pain?
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Patient’s self report is the standard for assessing the
existence and intensity of pain.
HCPs do not have the right to deprive any patient of
appropriate assessment and treatment because they
believe a patient is not being truthful.
Pain is reassessed and documented on a regular basis to
evaluate the effectiveness of treatment.
At a minimum, pain should be reassessed with each new
report of pain and before and after the administration of
analgesic agents
Pain assessment
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Pain Assessment
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o Location of pain, radiation of pain. o Intensity (severity): using a reliable and valid pain assessment tool, e.g., numerical rating scale & FACES pain scale, visual analog scale).
o Quality (e.g., “sharp,” “shooting,” or “burning”…to
identify neuropathic pain)
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Pain Assessment
when started? constant or intermitted?
Onset and duration
what make it worse or better?
Aggravating and relieving factors
Effect of pain on function and quality of life
(e.g., being able to sleep)
Comfort-function (pain intensity) goal
The patient’s culture, past pain experiences, perception and meaning of pain, distress that it cause, and medical history such as comorbidities, laboratory tests, and diagnostic studies
Other information
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Pain Assessment