R Superior Handling Exceptional Handling and stability at • the surgical site Natural Carrier Uses patented and proprietary • natural human tissue carrier Biocompatible and resorbable • Guaranteed Safety Allowash XG® proprietary steriliza- • tion technology yields final product with the same Sterility Assurance Level (SAL) as medical devices, without damaging inherent osteoin- ductive potential NOT FOR DISTRIBUTION IN THE UNITED STATES Predictable Regeneration Each lot of final product is im- • planted in a scientifically-proven in vivo rodent intramuscular model to confirm osteoinductivity (Urist standard model). Only final product exceeding LifeNet Health standards for osteoinductivity is released* PAD™ patented demineralization • technology un-shields growth fac- tors trapped within cortical bone to scientifically proven optimal levels** ADVANCING DBM TECHNOLOGY DBM PUTTY *Findings from an animal model are not necessarily predictive of human clinical results **Optimal residual calcium levels are only one of several variables which can contribute to optimal osteoinductivity
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Superior HandlingExceptional Handling and stability at •
Natural human tissue carrier •moldable with excellent handling properties•Resists migration•Ready-to-use•Sterile: 10• -6 Sterility Assurance Level (SAL)
Effect(s) of the demineralization process on the 1. osteoinductivity of demineralized bone matrix. Zhang M, Powers R M, and Wolfinbarger L. J Periodontol 1997; 68:1085-1092
The affects of residual calcium in decalcified 2. freeze-dried bone allograft in a critical-sized defect in the Rattus norvegicus calvarium . Turonis JW, McPherson JC 3rd, Cuening MF:. J Oral Implantol. 2006;32(2):55-62
Effects of Varying degrees of Allograft 3. Decalcification on the Cultured Porcine Osteoclast cells . Herold RW, Pashley DH, Cuening MF J Periodontol. 2002 Feb; 73(2):213-9
BMP depletion occurs during prolonged acid 4. demineralization of bone: characterization and implications for graft preparation. Pietrzak WS, Ali SN, Chitturi D, Jacob M, Woodell-May JE. Cell Tiss. Bank 2007 (Published on line)
Enhancement of osteoblast proliferation in vitro 5. by selective enrichment of demineralized freeze-dried bone allograft with specific growth factors. Mott DA., Mailhot J, Cuenin MF, Sharawy M, Borke J; J Oral Implantol 2002;28(2):57-66
DbM PuttyoRdeR code volUme
BF-1000-001 .5 cc
BF-1000-002 1 cc
BF-1000-003 2.5 cc
BF-1000-004 5 cc
BF-1000-005 10 cc
Cleaned & Sterilized withDemineralized with
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The new ReadiGraft® BLX Cancellous Sponge from LifeNet Health is an ideal natural
scaffold for cellular ingrowth in spine bone void applications. Its flexible cancellous
structure provides optimal flexibility and absorption that conforms to and fills most
bone void defects and resists migration from the surgical site. A proprietary deminer-
alization process used for ReadiGraft BLX Cancellous Sponge exposes natural growth
factors present in allograft tissue. You can have confidence in the all-allograft solution
for your spine applications with ReadiGraft BLX Cancellous Sponge.
Confidence in the Natural Choice.
Natural Scaffold for Healing and Cellular Ingrowth*:
Compresses to fit inside •bone voidsAbsorbent (blood, bone marrow •aspirate or platelet rich plasma)Resists migration from surgical site •Contains exposed growth factors •with osteoinductive potential
lifeNet Health: A Global leader in Regenerative Medicine
CuBeoRDeR CoDe SIZe
OSC1003 8 x 8 x 8 mm
OSC1000 10 x 10 x 10 mm
OSC1001 12 x 12 x 12 mm
OSC1002 14 x 14 x 14 mm
FIlleRoRDeR CoDe SIZe
OSF2000 2.5 cc
OSF2001 5 cc
OSF2002 10 cc
STRIpoRDeR CoDe SIZe
OSS3004 20 x 25 x 6 mm
OSS3005 15 x 20 x 6 mm
OSS3006 10 x 20 x 8 mm
ReadiGraft® blx Cancellous SpongeProvides natural scaffold for healing and •cellular ingrowth*
Compresses to fit irregular voids•Absorbs fluid (blood, bone marrow aspirate or •platelet rich plasma)Resists migration from surgical site•Contains exposed natural growth factors with •osteoinductive potential
Processed with Allowash XG,® shown to sterilize• to a Sterility As-surance Level of 10-6—the same sterility level of medical devicesAvailable in Cube, Strip and Filler configurations•