Das Fraunhofer IKTS als Innovativer partner im Bereich Bio ...€¦ · © Fraunhofer DAS FRAUNHOFER IKTS ALS INNOVATIVER PARTNER IM BEREICH BIO- UND MEDIZINTECHNIKAndreas Lehmann,

© Fraunhofer

DAS FRAUNHOFER IKTS ALS INNOVATIVER PARTNER IM BEREICH BIO- UNDMEDIZINTECHNIKAndreas Lehmann, Dr. rer. nat. Jörg Opitz

Medizintechnik in Sachsen

07.12.2016

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Our Business Divisions

MATERIALS ANDPROCESSES

MECHANICAL AND AUTOMOTIVE ENGINEERING

ELECTRONICS ANDMICROSYSTEMS

ENERGYMATERIALS ANDPROCESS ANALYSIS

OPTICS

BIO- AND MEDICALTECHNOLOGY

ENVIRONMENTAL ANDPROCESSENGINEERING

SYSTEMS EXPERTISE

TECHNOLOGY

EXPERTISE

WERKSTOFF-KOMPETENZ

MATERIALS DIAGNOSTICS

ReliabilityQuality assurance

Fraunhofer IKTS in profile

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Business DivisionBio- and Medical Technology

Competencies

� Development, processing and integration ofbiomaterials

� Shaping and surface technologies

� Microsystems technology

� Sensors and actuators

� Integration of functional mechatronic components

� (Bio)medical analytics and diagnostics

Dental technology

Implants/endoprosthetics

Instruments

Medical components

Biosensors and actuators

Analytics and diagnostics

Fraunhofer IKTS - BioMed

Applications

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CompetenciesBiomaterials

Development of customized biomaterials with defined property and structural parameters

Material groups

� Oxide ceramics as a high purity dense or porous bioceramics based on Al2O3 and ZrO2 (ATZ, ZTA, Y-TZP, Ca3(PO4)2) and HAP

� ceramic (lithium)

� Foam ceramic and metal foams

� Oxide and non-oxide ceramics with specific electrical, thermal and mechanical features

� Polymer ceramics and composites

� Individual material development

� DIN EN ISO 9001:2008 und EN ISO 13485

� Scale-Up to the pre-industrial scale

BioMed - competencies

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CompetenciesSensor and actuator

Development of functional materials, miniaturized components and systems

� Ceramic micro system technology (HTCC, LTCC)

� Thick film (screen, template, pad printing)

� Thin film technology (CVD, PECVD, ALD)

� Direct writing method (aerosol, inkjet)

� Biocompatible assembly and packaging technology

� Housing und Interfaces

� Functional components (di-, piezo and ferroelectrics)

� Linking structural and functional ceramics

� Application centres fortechnology testing

BioMed - competencies

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CompetenciesCharacterization

Monitoring & testing and diagnostic methods

� Complex material characterization on nano, micro and macro levels (TEM, SEM, AFM, AFAM)

� Biophysical characterization body and surfaces

� Development of in vivo and in vitro analysis systems and diagnostic systems

� Cell Tissue Monitoring

� Investigation of stimulation and suppression processes

� Fluorescence-based tumor diagnosis

� Quality assurance of production processes (inline und post mortem)� Fraunhofer IKTS branch

materials diagnostics

� Service and methoddevelopment

BioMed - competencies

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ApplicationsImplants

Material development

� Biofunctional and biomimetic ceramics

� Oxid ceramic based on Al2O3 and ZrO2

� High purity dense or porous Al2O3 bioceramics with sub-µm/nano-structures for shaped implants

� Foam ceramics and metal foams for bone replacement material

Technology development

� Foaming- and molding technologies, slip casting, sol-gel and plasma coating, generative techniques

� Bioceramic surface and shape body design

Knee endoprosthesis

BioMed - applications

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ApplicationsDental ceramics

Customer-specific material development

� Oxid ceramic based on Al2O3, ZrO2 and their dispersions with finely dispersed microstructure and high strength

� ceramic materials based on Li2Si2O5

Efficient process development

� Slip casting of ceramic components with complex geometries

� Closed CAD / CAM process chain certified EN ISO 13485:2003 + AC:2009

� 3D digitizer

Dental ceramics under UV illumination

SEM image Y-TZP

BioMed - applications

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ApplicationsBiosensors and -actorsSensors for diagnostics

� Multisensor-Arrays

� Cell Tissue Monitoring

� Development of nanoparticles for diagnostics

Bioactors

� Functional stimulation module (electric / acoustic / mechano-stimulation in vitro and in vivo)

� Ultrasonic transducer arrays for particle manipulation

Energy systems

� Scalable power transmission systems ex-vivo to in vivo (eg. for theranostical hip implants)

Mobile power transmissionsystem

Ultrasonic transducer arrays for particle manipulation

BioMed - applications

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ApplicationsMonitoring systems / testing and diagnostic systems

Process development

� Qualification optical diagnostics for medical and life sciences (OCT, Nanoraman)

� Monitoring of cell and bacterial growth processes

� Sensors for the detection of biogenic and biosynthetic polymers

� Intraocular pressure measurement using air-ultrasound

� Sterility detection by nanoparticles (SteriHealth®)

Device development

� Fluorescence-based cancer diagnostic (OCD) 3D visualization of a tooth using optical coherence tomography

BioMed - applications

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ApplicationsSurgical instruments and components

Materials, technology and component developments

� (Micro) Surgical instruments and cutting materials

� Ceramic tips for minimally invasive surgery

� Functional (conductive, bioactive, biosuppressive) layers

� Functional films

� Ceramic springs

� Components for X-ray equipment

Plasma gel-coated surgicalinstrument

BioMed - applications

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THANK YOU FOR YOUR ATTENTION!

Contact: Andreas Lehmann

Fraunhofer IKTSMaria-Reiche-Str. 201109 Dresden+49 351 [email protected]