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Cytomegalovirus-based vaccine expressing a modified tumor antigen induces
potent tumor-specific CD8+ T-cell response and protects mice from melanoma
Zhijuan Qiu1, Huakang Huang1, Jeremy M. Grenier1, Oriana A. Perez1, Henry M. Smilowitz2,
Barbara Adler3, and Kamal M Khanna1,*
1Department of Immunology, University of Connecticut Health Center, Farmington, USA;
2Department of Cell Biology, University of Connecticut Health Center; 3Max von Pettenkofer-
Institute for Virology, Ludwig-Maximilians-University Munich, Munich, Germany
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
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Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
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Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044
Published OnlineFirst January 29, 2015.Cancer Immunol Res Zhijuan Qiu, Huakang Huang, Jeremy M Grenier, et al. and protects mice from melanomaantigen induces potent tumor-specific CD8+ T cell response Cytomegalovirus based vaccine expressing a modified tumor
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Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Author Manuscript Published OnlineFirst on January 29, 2015; DOI: 10.1158/2326-6066.CIR-14-0044