CURRICULUM VITAE MOHAMMAD FAISAL PhD (AMU), Former Postdoctoral Fellow (CIB, Madrid, Spain) & FSERS PERSONAL DETAILS Associate Professor of Plant Biotechnology Department of Botany & Microbiology, College of Science, King Saud University Riyadh-11451, KSA. *: [email protected]; [email protected](+966-(011)-4675877; È+966-556691485 http://fac.ksu.edu.sa/mofaisal/home https://orcid.org/0000-0002-8176-1527 https://researchgate.net/profile/Mohammad_Faisal5 RESEARCH INTERESTS: Plant Biotechnology My research program currently focuses on several areas of biotechnology/molecular biology in higher plants. We use combination of techniques for in vitro morphogenesis, tissue culture, mass propagation and genetic transformation in plants of economic importance and characterization of plants using molecular markers and flow cytometry. Encapsulation of plant propagules for germplasm conservation, storage and exchange. Recently, we have begun to investigate the comparative transcriptome of potential medicinal plants to identify genes involved in biosynthesis of secondary metabolites. My research also includes the interaction of nanoparticles and xenobiotics with plants and their toxicological effects and mechanism of interaction at cellular and molecular levels in edible crops. EDUCATION BSc (Hons) (1997) AMU, Aligarh, India Botany MSc (2000) AMU, Aligarh, India Botany (Plant Tissue Culture & Biotechnology) MPhil (2002) AMU, Aligarh India Botany (Plant Tissue Culture & Biotechnology) PhD (2006) AMU, Aligarh India Botany (Plant Tissue Culture & Biotechnology) PhD thesis title: Tissue Culture and Plant Regeneration Studies in Tylophora indica & Rauvolfia tetraphylla RESEARCH ACTIVTIES/APPOINTMENTS: 13 Years of experiences after PhD Position Institutes/University Dates Associate Professor Department of Botany & Microbiology, College of Science, King Saud University (KSU), Saudi Arabia. 2017 – Current Assistant Professor Department of Botany & Microbiology, College of Science, KSU, Saudi Arabia 2011 – 2017 Post-Doctoral Fellow Centro de Investigaciones Biológicas, CSIC, Madrid, Spain. 2010 –2011 Young Scientist Department of Botany, Aligarh Muslim University (AMU), Aligarh, India. 2007 – 2009 Research Fellow Department of Botany, AMU, Aligarh India. 2001 – 2007 PARTCIPATION IN RESEARCH PROJECTS: Projects title Position Time span Ø Environmental Biotechnology - Research Group Project (RG- 175), Deanship of Scientific Research, King Saud University Principal Investigator 2018-19
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RESEARCHINTERESTS:PlantBiotechnologyMy research program currently focuses on several areas of biotechnology/molecular biology inhigher plants.We use combination of techniques for in vitromorphogenesis, tissue culture,masspropagationandgenetictransformationinplantsofeconomicimportanceandcharacterizationofplants using molecular markers and flow cytometry. Encapsulation of plant propagules forgermplasmconservation,storageandexchange.
My research also includes the interaction of nanoparticles and xenobioticswith plants and theirtoxicologicaleffectsandmechanismofinteractionatcellularandmolecularlevelsinediblecrops.
§ Cell &Molecular Biology Techniques, 12-19 November 2013, Centro de InvestigacionesBiológicas,BiologicalResearchCentre(CIB),CSIC,Madrid,Spain
§ CIMAP Winter School – 2006 (CWS-2006): Recent Techniques in Structural andFunctional Genomics, 15-24December 2006 at Central Institute ofMedicinal & AromaticPlants,Lucknow,India.
DoctorofPhilosophy,AligarhMuslimUniversity,Aligarh,India(2019-Current).SOCIAL/COMMUNITYSERVICES:§ Organized a workshop “Tomato Workshop: Disease and Management (2019) in local
PUBLICATIOSINISI/REFEREEDJOURNALS:1. Faisal M., Abdel-Salam E.M., and Alatar A.A. (2021) Artificial microRNA-based RNA
interference and specific gene silencing for developing insect resistance in Solanumlycopersicum.Agronomy.11(1):136;https://doi.org/10.3390/agronomy11010136.IF=2.60
4. Faisal M., Abdel-Salam E.M., Alatar A.A. and Qahtan A.A. (2021) Induction of somaticembryogenesis inBrassica juncea L. and analysis of regenerants using ISSR-PCR and flowcytometer.SaudiJournalofBiologicalSciences28(1):1147-1153.IF=2.63
5. AhmadA.,AhmadN.,AnisM.,AlatarA.A.,QahtanA.A.,FaisalM.,(2020)Gibberellicacidandthidiazuron promote micropropagation of an endangered woody tree (Pterocarpusmarsupium Roxb.) using in vitro seedlings. Plant Cell Tissue & Organ Culture DOIhttps://doi.org/10.1007/s11240-020-01969-1.IF=2.19
6. Abdel-Salam E.M., Alatar A.A. Qahtan A.A., and FaisalM. (2020)De novo ComprehensiveTranscriptome Assembly and Analysis from different Organs ofRuta chalepensis RevealedGenesInvolvedinRutinBiosynthesis.Intl.J.Agric.Biol.24:1795-1805.IF=0.82
7. Nabi R., Alvi S.S., Shah S.M., Ahmad S., Faisal M., Alatar A.A. and Khan M.S. (2020) Abiochemical&biophysicalstudyonin-vitroanti-glycatingpotentialofiridinagainstd-RibosemodifiedBSA.ArchivesofBiochemistryandBiophysics686:108373.IF=3.39
8. SharmaN.,FaisalM.,AlatarA.A.,KhanM.K.A.,AhmadS.andSalmanA.(2020)Design,SAR,andmetabolism study of Cruciferae family compound (Spirobrassinin) and its analogs forantiangiogenic potential targeting Hsp90. Current Proteomics DOI:10.2174/1570164617999200731000719.IF=0.75
11. KhanI.,FaisalM.,MehfoozS.,AlatarA.A.,andAnsariI.A. (2020)AndrographolideInducesApoptosisandCellCycleArrestthroughInhibitionofAberrantHedgehogSignalingPathwayin Colon Cancer Cells. Nutrition and Cancer DOI:https://doi.org/10.1080/01635581.2020.1828942.IF=2.63
14. Abdel-SalamE.M.,FaisalM.,AlatarA.A.,SaquibQ.andAlwathnaniH.A.(2020)ComparativeAnalysis betweenWild and Cultivated Cucumbers Reveals Transcriptional Changes duringDomesticationProcess.Plants9(1):63.IF=2.63
15. Cherian T., Ali K., Saquib Q., Faisal M., Wahab R. and Musarrat J. (2020) CymbopogoncitratusFunctionalized Green Synthesis of CuO-Nanoparticles: Novel Prospects asAntibacterialandAntibiofilmAgents.Biomolecules10(2):169.IF=4.69
22. OklaM.K.,AlamriS.A.,AlatarA.A.,HegazyA.K.,Al-GhamdiA.A.AjaremJ.S.,FaisalM.,Abdel-Salam E.M., Ali H.M., Salem M.Z.M., and Abdel-Maksoud M.A., (2019) Antioxidant,Hypoglycemic, and Neurobehavioral Effects of a Leaf Extract of Avicennia marina onAutoimmuneDiabeticMice.Evidence-BasedComplementaryandAlternativeMedicine.2019,ArticleID1263260,https://doi.org/10.1155/2019/1263260.IF=1.98.
24. RehmanS.,FaisalM.,AlatarA.A.andAhmadS.(2019)Physico-chemicalchangesinducedinserum proteins, Immunoglobulin-G and Fibrinogen by reactive carbonyl species,Methylglyoxal.CurrentProteinandPeptideScience.20:1-10.IF=1.88
25. Wahab R., Khan F., Gupta A., Wiggers H., Saquib Q., Faisal M. and Ansari S.M. (2019)Microwave plasma-assisted silicon nanoparticles: Cytotoxic, molecular, and numericalresponsesagainstcancercells.RSCAdvances9:13336-13347.IF=3.04
26. GuerrieroG.,BerniR.,Muñoz-SanchezJ.A.,AponeF.,Abdel-SalamE.M.,QahtanA.A.,AlatarA.A.,CantiniC.,CaiG.,HausmanJ.F.,SiddiquiK.S.,Hernández-SotomayorS.M.T.,FaisalM.(2018)Production of Plant Secondary Metabolites: Examples, Tips and Suggestions forBiotechnologists.Genes9(6)309-331.IF=3.31
28. KhanMi,AhmadN.AnisM,AlatarAA,FaisalM.(2018)InvitroconservationstrategiesfortheIndianwillow (Salix tetraspermaRoxb.), a vulnerable tree speciesviapropagation throughsyntheticseeds.BiocatalysisandAgriculturalBiotechnology16:17-21.
31. AlouffiS.,FaisalM.,AlatarA.A.,AhmadS.(2018)OxidativeModificationofLDLbyVariousPhysicochemical Techniques: Its Probable Role in Diabetes Coupled with CVDs. BioMedResearchInternational.2018,ArticleID7390612,7pages.IF=2.27
32. Siddiqui Z., FaisalM., Alatar A.A., Ahmad S. (2018) Glycation of hemoglobin leads to theimmunogenicityas a resultofneoepitopegeneration. International JournalofBiologicalMacromolecules.123-427-235.IF=3.90.
and mitochondrial dysfunction to trigger apoptosis in human lymphocytes and rat bone-marrowcells.HistochemistryandCellBiology149:127-141.IF=2.64
34. Gil K.E., KimW.Y., Lee H.J., FaisalM., Saquib Q., Alatar A.A., Park, C.M. (2017) ZEITLUPEcontributestoathermoresponsiveproteinqualitycontrolsysteminArabidopsis.PlantCell29(11):2882-2894.IF=8.63.
35. Javed S.B., Alatar A.A., Anis M. and Faisal M. (2017) Synthetic seeds production andgerminationstudies,forshorttermstorageandlong-distancetransportofErythrinavariegataL.:Amultipurposetreelegume.IndustrialCropsandProducts105:41–46.IF=3.18.
37. AlatarA.A.,FaisalM., Abdel-SalamE.M., CantoT., SaquibQ., Javed S.B., El-SheikhM.A., Al-Khedhairy A.A. (2017) Efficient and reproducible in vitro regeneration of Solanumlycopersicum and assessment genetic uniformity using flow cytometry and SPARmethods.SaudiJournalofBiologicalSciences24:1430-1436,IF=2.56.
38. JavedS.B.AlatarA.A.,BasahiR.,AnisM.andFaisalM.(2017)Copperinducedsuppressionofsystemic microbial contamination in Erythrina variegata L. during in vitro culture L.:Combatingendogenousinfection.PlantCell,Tissue&OrganCulture.28:249-258.IF=2.002.
40. Alatar A.A., Ahmad N., Javed S.B., Abdel-Salam E.M. and Faisal M. (2017) Two-waygermination system of encapsulated clonal propagules of Vitex trifolia L.: an importantmedicinalplant.JournalofHorticulturalScience&Biotechnology.92:175-182.IF=0.53.
44. Shahid A., Ahmad N., Anis M., Alatar A.A. & Faisal M. (2016)Morphogenic responses ofRauvolfiatetraphyllaL.culturestoCu,ZnandCdions.RendicontiLincei.ScienzeFisicheeNaturali27:369-374.IF=0.69.
45. SaquibQ.,SiddiquiM.A.,AhmedaJ.,Al-SalimaA.,AnsariS.M.,FaisalM.,Al-KhedhairyaA.A.,MusarratdJ.AlWathnaniH.A.,AlatarA.A.&Al-ArifiS.A.(2016)Hazardsof lowdoseflame-retardants (BDE-47 and BDE-32): Influenceon transcriptome regulation and cell death inhumanlivercells.JournalofHazardousMaterials308:37-49.IF=6.06.
46. Alatar A.A., FaisalM., Hegazy A.K., Alwathnani H.A. & OklaM.K. (2015). Clonal in vitromultiplication of grey mangrove and assessment of genetic fidelity using single primeramplification reaction (SPAR) methods.Biotechnology Biotechnological Equipment 29:1069-1074.IF=1.05.
48. GargV.,PermarV.,ParkhiV.,ManiE.,AlatarA.A.,FaisalM.&PraveenS.(2015).Differentiatingtomatoleafcurlvirusespossessingmono/bipartitegenomesusingreplicasegene-basedPCRassay: implications for developing virus specific resistance. J. PlantBiochem.Biotechnol.24:461–465.IF=0.95.
50. KaurH.,YadavC.B.,AlatarA.A.,FaisalM.,JyothsnaP.,Malathi,V.G.andPraveenS.(2015)Geneexpression changes in tomato during symptomdevelopment in response to leaf curl virusinfection. J. Plant Biochem. Biotechnol. 3: 347-354. DOI 10.1007/s13562-014-0280-8).IF=0.95.
55. Siddiqui M.H., Al-Whaibi M.H., Faisal M. and Al Sahli A.A. (2014) Nano-silicon dioxidemitigatestheadverseeffectsofsaltstressonCucurbitapepoL.EnvironmentalToxicologyandChemistry33:2429-2437.IF=2.99.
56. Hegazy A.K. Alatar A.A. Thomas J., Faisal M., Alfarhan A.H. and Krzywinski K. (2014)CompatibilityandcomplementarityofindigenousandscientificknowledgeofwildplantsinthehighlandsofsouthwestSaudiArabia.JournalofForestryResearch25:437−444.IF=0.77.
57. FaisalM.,SaquibQ.,AlatarA.A.,Al-KhedhairyA.A.,Hegazy,A.K.,Musarrat,J.(2013)Phytotoxichazards of NiO-nanoparticles in tomato: A study on mechanism of cell death. Journal ofHazardousMaterials250-51:318-332.IF=6.06.
58. AhmadN.,KhanM.I.,AhmedS., Javed,S.B.,FaisalM.,AnisM.,KhanS.,UmairS.M.(2013).Change in totalphenoliccontentandantibacterialactivity in regenerantsofVitexnegundo.ActaPhysiologiaPlantarum35:791-800.IF=1.36.
59. FaisalM.,AlatarA.andHegazyA.K.(2013)Molecularandbiochemicalcharacterization inRauvolfia tetraphylla plantlets grown from synthetic seeds following in vitro cold storage.AppliedBiochemistryandBiotechnology169:408-417.IF=1.75.
61. A.K.Hegazy,S.L.Al-Rowaily,M.Faisal,A.A.Alatar,M.I.El-Bana,A.M.Assaeed(2013)Nutritivevalue and antioxidant activity of some edible wild fruits in the Middle East. Journal ofMedicinalPlantsResearch7:938-946.
62. A.K.Hegazy, S.L. Al-Rowaily,H.F.Kabiel,M.Faisal,M.H. Emam (2013) Variations of PlantMacronutrients and Secondary Metabolites Content in Response to RadionuclidesAccumulation.JournalofBioremediation&Biodegradation4:185-195.
64. Ahmad N., Faisal M. and Anis M. (2013) Role of PGR on in vitro shoot propagation inCyamopsis tetragonoloba L. (Taub.): a drought tolerant grain legume. Rendiconti Lincei-ScienzeFisicheeNaturali24:7-12.IF=0.69.
66. N. Ahmad,M. Faisal, N. Fatima and M. Anis (2012) Encapsulation of microcuttings forpropagationandshort-termpreservationinRutagraveolensL.:aplantwithhighmedicinalvalue.ActaPhysiologiaePlantarum34:2303-2310.IF=1.36.
68. Alatar A.A., Faisal M., Hegazy AK and Alwathnani H. A. (2012) High frequency shootregenerationandplantestablishmentofRauvolfiaserpentina-anendangeredmedicinalplant.JournalofMedicinalPlantsResearch6:3324-3329.
69. ShahzadA.,FaisalM.,AhmadN.,AnisM.,AlatarA.A.andHendA.A.(2012)Anefficientsystemfor in vitro multiplication of Ocimum basilicum through node culture.African Journal ofBiotechnology11:6055-6059.
70. PilarS.Testillano,MohammadFaisal,HéctorRodríguez-Sanz,JoséAntonioManzanerayMªCarmenRisueño(2011)Pollenandsomaticembryogenesis inQuercussuber: searching forcommon markers and features in two in vitro embryo developmental pathways. SECIVTNovenaReunion,Spain,April27-29,2011,p.65.
71. Faisal M and Anis M (2010) Changes in photosynthetic activity, pigment composition,electrolyteleakage,lipidperoxidation,andantioxidantenzymesduringexvitroestablishmentofmicropropagatedRauvolfiatetraphyllaplantlets.PlantCell,Tissue&OrganCulture99:125–132.IF=2.003.
73. FaisalM and AnisM (2009)Effect of light irradiations on photosyntheticmachinery andantioxidativeenzymesduringexvitroacclimatizationofTylophoraindicaplantlets.JournalofPlantInteractions5:21-27.IF=1.62.
74. Khan H, Faisal M and Anis M (2008) Plant regeneration via somatic embryogenesis inSolanummolngenaL.Phytomorphology4:153-157ISPM,India.
75. FaisalM,ShahzadAandAnisM(2008)Somaticembryogenesisandplantregenerationfromnodal explants in Psoralea corylifolia L. International Journal of Plant DevelopmentalBiology2:111-113.
83. Faisal M, Singh S and Anis M (2005) In vitro regeneration and plant establishment ofTylophoraindica(Burm.f.)Merrill:petiolecallusculture.InVitroCell.Dev.Biol.Plant.41:511-515.IF=1.02.
84. Anis M and Faisal M (2005) In vitro regeneration and mass multiplication of Psoraleacorylifolia–anendangeredmedicinalplant. Indian JournalofBiotechnology 4:216-264.IF=0.28.
89. Faisal M and Anis M (2002) Rapid in vitro propagation of Rauvolfia tetraphylla L. - anendangeredmedicinalplant.Physiology&MolecularBiologyofPlants8:295-299.India.IF=0.88.
90. Shahzad A, Faisal M, Husain MK and Siddiqui SA (2001) Micropropagation in HibiscusmutabilisL.-anornamentalplant.Bionotes3:69.India.
91. Shahzad A, Husain MK, Faisal M, and Siddiqui SA (2001) Nodular callus formation andproductionofflowerbudsinvitrofromshoottipcultureofHelianthusannuus.Bionotes3:61.India.
3. Ahmad N., Faisal M., Hussain S.A. and Anis M. (2018) Regulation of Morphogenesis andImprovement inShootMultiplication inVitexSpeciesUsingThidiazuron. In:Thidiazuron:FromUreaDerivativetoPlantGrowthRegulator(Eds.)AhmadNandFaisalM.,SpringerNature,pp.343-350.
4. SaquibQ. SiddiquiM.A., Ahmad J., Ansari S.M.,FaisalM.,WahabR., Al-KhedhairyA.A. andMusarratJ.(2018)NickelOxideNanoparticlesInducedTranscriptomicAlterationsinHEPG2Cells. In:CellularandMolecularToxicologyofNanoparticles(Eds.)SaquibQ.FaisalM.KhedhairyA.A.&AlatarA.A.,SpringerNature,pp.429-438.
5. Hussain S.A., AhmadN., AnisM., Alatar A.A. andFaisalM., (2018) Role of Thidiazuron inModulation of Shoot Multiplication Rate in Micropropagation of Rauvolfia Species. In:Thidiazuron:FromUreaDerivativetoPlantGrowthRegulator(Eds.)AhmadNandFaisalM.,SpringerNature,pp.429-438.
Nanoparticles.SpringerNature.6. Faisal M., Anis M. and Alatar A.A. (2012) Plant Tissue Culture: An Effective Tool of
BiotechnologyforConservationofMedicinalPlants.LambertAcademicPublisher.CONFERENCES/SYMPOSIAPRSENTATION/ATTENDED1. InternationalWebinaronProductionofAndrogenicHaploidsandDoubledHaploids in
7. National Conference on “Monitoring and Management of Drinking Water Quality(MMDWQ)washeldattheUttarakhandStateCouncilforScienceandTechnology,Dehradun,Uttarakhand,December21-23,2015.
10. 5thInternationalCropScienceCongress&Exhibition.InternationalConventionCentre,Jeju,Korea,April13-18,2008,p.127-128.-Photosyntheticactivity,malondialdehydecontentand antioxidant enzymes in leaves during ex-vitro establishment of micropropagatedRauvolfiatetraphyllaplantlets.
11. National Symposium on Plant Biotechnology. FRI, Dehradun, Oct., 12-14, 2006. p. 95. -PhotosyntheticpigmentsandantioxidantenzymesinleavesduringexvitroestablishmentofmicropropagatedTylophoraindicaplantlets.
12. Journal of Society for InVitroBiology. 41 A 47. SIVB, USA. - Thidiazuron InducedHighFrequency Shoot Induction andPlantRegeneration inPsoralea corylifolia - anEndangeredMedicinalPlant.
14. IUFRO International Conference on Multipurpose trees in the Tropics: Assessment,GrowthandManagement.AridForestResearch Institute (ICFRE) Jodhpur,Nov.22-25,p.282.-SomaticembryogenesisandregenerationofplantletsformnodalexplantsofSantalumalbumL.
15. National Symposium on Plant Biology and Biodiversity in Changing Environment.HamdardUniversity,NewDelhi.Dec.29-31,p.40.-InvitropropagationofPsoraleacorylifoliaL.
18. International Symposium on Plant Biodiversity: Conservation and Evaluation. BoseInstitute,Kolkata,Dec.17-20,2002.-Conservationofsomerareandendangeredmedicinalplantsadoptingbiotechnologicalapproaches.
19. XXIV Indian Botanical Conference, Hyderabad, Nov. 19-21, 2001 - In vitro induction ofmultiple shoots from nodal segment explants of Rauvolfia tetraphylla L.-an endangeredmedicinalplant.