1 Curriculum Vitae Mohammad Arfan Address & Contact Professor International Center for Chemical & Biological Sciences HEJ Research Institute of Chemistry University of Karachi, Karachi E-mail: [email protected]Contact # Cell: +923139226208, +92-91-5852560 (Res) Skype : rummanma1 Education-Qualification THESIS/DISSERTATION/POSTDOCTORAL # Title of Thesis Thesis/Year Research Supervisor 1 Coupling of Diazonium Salts with Active Methylene compounds M.Sc/ 1973-74 Dr. N.A. Zaidi 2 Stereochemistry of Nucleophilic Substitution at Carbon-Nitrogen Double Bond: Photochemistry of Alkyl Benzohydroxamates. Ph.D/ 1978-83 Prof. James E. Johnson, Dept. of Chemistry, Texas Womans University, USA 3 Synthesis of Aceanthrylene: Picosecond Pulse Laser Studies- Anti-Kasha Fluorescence. Robert A. Welch Foundation Postdoctoral Fellow/ 1983- 84 Prof. Benjmin F. Plummer, Dept. of Chem., Trinity University, Texas, USA. (Sponsor:Robert A. Welch Foundation, USA) 4 Hybridoma Technique- Purification of Monoclonal Antibodies and Antigens: Synthesis; of Antibody Drug Conjugates Immunodiagnosis and Therapy. Wadley Cancer Research Foundation Postdoctoral Fellow/ 1984- 1985 Sponsor: Wadley Institute of Molecular Medicine, Dallas, Texas, USA. High School Certification ….Government High School Shamozai, Swat, Kyhber Pukhtoon Khwa, Pakistan B.S…………….Postgraduate Jahan Zeb College, Saidu Sharif, Swat, Khyber Pukhtoon Khwa, Pakistan
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Curriculum VitaeMohammad Arfan
Address & ContactProfessor
International Center for Chemical & Biological SciencesHEJ Research Institute of ChemistryUniversity of Karachi, Karachi
M.Sc……………Department of Chemistry, University of Peshawar, Peshawar, Khyber Pukhtoon Khwa, Pakistan
Ph.D……………Department of Chemistry, Texas Womans’University, Denton, TX 75270, Denton, Texas, USA.
Fields of SpecializationOrganic Chemistry, Synthetic Organic Chemistry, Medicinal Chemistry,
Photochemistry, Physical organic chemistry, Molecular Medicine
Professional History
1. Lecturer, Department of Chemistry, University of Peshawar, Peshawar, Khyber Pukhtoon Khwa, Pakistan (1974-1978)
2. Teaching Assistant, Department of Chemistry & Biochemistry, Texas Woman’s University, Denton, Texas, USA (1978-1983)
3. Robert A.Welch Foundation Postdoctoral Fellow, Trinity University, San Antonio, Texas, USA (1983-1984)
4. Wadley Foundation Postdoctoral Fellow, Waldley Center for Molecular Medicine, Cancer Research Center, Department of Immunotherapy, Harry Hines Blvd., Dallas, Texas, USA (1984-1985)
5. Assistant Professor (1986-1992), Associate Professor (1992-2002), Professor & Director , (2002-2011) Institute of Chemical Sciences, University of Peshawar, Peshawar, Khyber Pukhtoon Khwa, Pakistan
6. Dean, Higher Education Quality Assurance/Director, Quality Enhancement Cell, University of Peshawar, Peshawar, Pakistan (2004-2006)
7. Professor, International Center for Chemical and Biological Sciences, University of Karachi, Karachi,Pakistan (2014-continued)
HIGHER EDUCATION QUALITY ASSURANCE
1. Workshop on “ Organizational Structure and Mechanism for Planning of Development Projects/Programmes in Pakistan” , 27the November, 2004, Higher Education Commission, Regional Centre, Peshawar.
2. Certificate in “Quality Assurance in Education” , Executive Training Workshop organized by Pakistan Institute of Quality Control at Hotel Margala, November 29, 2004.
3. 3 week “TRAINING COURSE TO MEET INTERNATIONAL STANDARDS OF UNIVERSITY ACADEMIC” taught by Dr.Mahmood A.Butt, Professor, Eastern Illinois University, USA at The University of Azad Jammu & Kashmir, December 20, 2004 to January 2005.
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4. Certificate in “ Quality Enhancement Framework in Higher Education” The Quality Assurance Agency & Learning Innovation, Higher Education Commission, July 25-26, 2005.
5. Certificate in “ Auditor Training Workshop” Australian Universities Quality Agency (AUQA), Melbourne, Australia , 28-30th November 2005. Sponsored by Asia Pacific Quality Network (APQN), Australia and Higher Education Commission, Pakistan.
6. Certificate in “ Quality Assurance in Higher Education” Training Workshop organized by the Pakistan Institute of Quality Control (PIQC), Rawalpindi, March 20, 2006.
7. Certificate in “Quality Assurance in Higher Education” Training Workshop organized by the Pakistan Institute of Quality Control (PIQC), Lahore, March 09,
HIGHER EDUCATION PLANNING AND MANAGEMENT
1. Member, Higher Education National Curriculum Committee, HEC, Islamabad (2006-2010). Development of organic chemistry national curriculum for undergraduate program in Pakistani universities and colleges.
2. Member, Advanced Studies and Research Board (ASRB), University of Peshawar (1990- 2007). Overseeing university research programs at MS, M.Phil and Ph.D levels, assessment and approval of research topics and research proposals submitted by students.
3. Member, Departmental Program and Research Assessment Committee (1988-2011).
4. Member,University Scholarship Committee (2002-2010).5. Member, Selection Boards of several universities in Pakistan.
Research InterestMedicinal Chemistry including: Synthesis, Characterization and bioactivity evaluation of bioactive heterocyclic compounds. Development of new, green and cost effective synthetic methods and microwave assisted organic synthesis, Isolation and Characterization of bioactive natural products from local medicinal plants, Functional mesospheric and nanospheric materials, Multimodal nanoparticles platforms and Quantum Dots for Theranostics, Natural and Synthetic Antiviral agents.
2. Research publications total Impact Factor (Research Gate) : 143.5
3. Among the top three productive scientists in the University of Peshawar “Productive Scientists of Pakistan” since 2003 according to the annual ranking by the Pakistan Council for Science & Technology, Islamabad.
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4. Award of a research support grant (Rs. One million) by the Pakistan Science Foundation in 2005 in recognition of as one of the productive scientists and technologists in Pakistan. Several financial research grants obtained from the University of Peshawar own resources to support M.Phil and Ph.D supervised research projects.
5. Best University Teacher Award (Higher Education Commission, Pakistan)-2004
6. Teaching Assistantship, Texas Woman’s University, Denton, Texas, USA
7. Robert A. Welch Foundation Postdoctoral Fellow (Texas, USA)- 1983-1984
8. Wadley Foundation Postdoctoral Fellow (Dallas, Texas, USA)-1984-1985
9. Fellow Chemical Society of Pakistan-2007
TRAINING COURSES / WORKSHOPS
1. Postgraduate Training Course on “Nuclear and Other Advanced Techniques Techniques in Agricultural and Biological Research”, Nuclear Institute of Agriculture and Biology (NIAB) Faisalabad, Pakistan (26th November to December 1977).
2. International Workshop on “Protein Sequencing”, HEJ Research Institute of Chemistry, University of Karachi (December 1, 10 1989).
3. International Symposium on “Protein Structure Function Relationship”, HEJ Research Institute of Chemistry, University of Karachi (December 11-14, 1989).
4. National Workshop on “Theoretical and Computational Chemistry”, National Academy of Higher Education, University Grants Commission, Pakistan (February 6-11, 1993).
5. Training Course in “Frontier Areas of Organic Synthesis” Sponsored by United Nations Industrial Organization (UNIDO) and International Centre for Science and High Technology (ICS) and held at the Indian Institute of Science and Jawahar Lal Nehru Centre for Advanced Scientific Research, Bangalore, India from December 8, to December 18, 1993.
Supervisory experience
Ph.D supervised…………………..6
M.Phil supervised……………………16
M.S supervised…………………………73
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Research Publications1. TU Rahman, M Arfan, T Mahmood, W Liaqat, MA Gilani, G Uddin, Isolation,
spectroscopic and density functional theory studies of 7-(4-methoxyphenyl)-9H-
furo [2, 3-f] chromen-9-one: A new flavonoid from the bark of Millettia ovalifolia
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 146, 24-
32, 2015
2. A Rauf, G Uddin, H Khan, M Arfan, BS Siddiqui Bioassay-guided isolation of
antibacterial constituents from Diospyros lotus roots Natural Product Research 1-
3, 2015
3. A Rauf, G Uddin, H Khan, BS Siddiqui, M Arfan Anti-hyperalgesic activity of crude extract and 7-methyljuglone of Diospyros lotus roots Natural Product Research, 1-4, 2015
4. A Rauf, G Uddin, A Khan, BS Siddiqui, M Arfan, K Dalvandi, TB HaddaPistagremic acid, a novel β-secretase enzyme (BACE1) inhibitor from Pistacia integerrima Stewart Natural Product Research 1-4, 2015
5. A Rauf, G Uddin, BS Siddiqui, A Khan, H Khan, M Arfan, N Muhammad, In-
vivo antinociceptive, anti-inflammatory and antipyretic activity of pistagremic
acid isolated from Pistacia integerrima Phytomedicine 21 (12), 1509-1515,2015
6. M Ali, A Latif, K Zaman, M Arfan, D Maitland, H Ahmad, M Ahmad Anti-ulcer xanthones from the roots of Hypericum oblongifolium Wall Fitoterapia 95, 258-265, 2014
7. SH Hussain, A Latif, RJ Cox, TJ Simpson, M Ali, M Arfan, G Uddin, Phytochemicals from the aerial parts of Ligularia thomsonii and their radical scavenging activity Phytochemistry Letters 7, 6-10, 2014
8. A Rauf, G Uddin, H Khan, BS Siddiqui, M Arfan, M Yousuf, A Hussain Parts of
Hedera helixL 2014
9. Abdul Latif, Syed Hamid Hussain, Mumtaz Ali, Mohammad Arfan, Manzoor Ahmed, Russell J Cox, Thomas J Simpson, Ghias Uddin A New Antioxidant
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Triterpenoid from the Stem Wood of Sorbus lanata Records of Natural Products 8 (1), 19-24,2014
10. TU Rahman, M Arfan, W Liaqat, G Uddin, MI Choudhary Isolation of a Novel
Indigoferamide-A from Seeds of Indigofera Heterantha Wall and its Antibacterial
Activity Records of Natural Products 8 (4), 412-416, 2014
11. Yong-Liang Shao, Lei Hua,Ya Li,Syed Hamid Hussain, Mohammad Arfan, Kun
Gao Guaianolides and elemanolides from Vernonia anthelmintica, Phytochemistry
Letters.Vol.7, 2014,14–18
12. Abdur Rauf, Ajmal Khan, Nizam Uddin, Mohammad Arfan, Ghias Uddin and
Muhammad Qaisar. Preliminary phytochemical screening, antimicrobial and
antioxidant activities of Euphorbia milli. Pakistan Journal of pharmaceutical
sciences. In press will be published in April 2, 2014
13. Chemical Composition and Biological evaluation of the Fixed Oils from the
Diospyros lotus Stewart. Pakistan Journal of Botany In press
14. Abdur Rauf, Ghias Uddin, Mohammad Arfan, Naveed Muhammad, Chemical
composition and biological screening of essential oils from Pistacia integerrima.
African Journal of Pharmacy and Pharmacology Vol. 7(20), pp. 1220-1224, 29
May, 2013.
15. Molecular docking of Diospyrin as a LOX inhibitory compound. Ghias Uddin,
Abdur Rauf*, Mohammad Arfana, Waliullah,Taj Ur Rehman, Amir Zada Khan,
Gowhar Ali, Bushra Rehman, M. Zia-ul-Haq , Journal of Saudi Chemical
Society online. 2013
16. Mohammad Arfan, Saira Gul Rabia Usman, Arshad Khan, Abdur Rauf, Naveed
Muhammad Syed Uzair Ali Shah, Ajmal Khan and Mumtaz Ali. The
Comparative Free Radical Scavenging Effect of Trigonella foenumgraecum,
Solanum nigram and Spinacia oleracea. Academic Journal of Plant Sciences 6 (3):
Mohammad Arfan, "Photochemistry of Alkyl-benzohydroxamates". Proc Natl.
Chem. Conf. (1) 1989,466-479.
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3. Mohammad Arfan, "Hybridoma Technology: A useful Biotechnology Tool for
Chemical and Medical Sciences". Proc. Natl. Chem. Conf.(1), 1989,665-673.
4. Mohammad Arfan and Haroon Rashid, "Rates of Acid-Catalyzed Geometric,
Isomerization of Methyl (z)-o-methylbenzohydroxamate". Proc. Natl. Chem.
Conf.( 1), 1989,686-691.
5. Khan, A., Joher, A., Arfan, M., Jia F., Pichyangkul, S., Berent, S., Hill, N.O.,
Bollon, A. "Acute Toxicity and Stability Studies on Tumor-Necrosis-Factor (TNF)
in Mice", Proceedings of the American Association of Cancer Research, 27,
March 1986, 320.
SEMINAR/SYMPOSIA/CONFERENCES/WORKSHOPS ATTENDED AND PAPERS RESENTED
1. Postgraduate Training Course on “Nucelar and other Advanced Techniques in Agricultural and Biological Research”, Nuclear Institute for Agriculture and Biological (NIAB), Faisalabad Pakistan (26th November to 8-18 December 1993).
2. 14th Annual Miniature Meeting of the American Chemical Soceity at Texas Women’s University, Denton, Texas, USA (April 3, 1981).
3. 187th American Chemical Soceity (ACS) National Meeting at St. Louis, Missouri, USA (April 8-13, 1984).
4. 187th ACS National Meeting Chicago, Illinois, USA (April 8-12, 1984). “Sterochemistry and Mechanisms of Amine Substitution Reactions at the Cabon-Nitrogen Double Bond”.
5. 188th ACS National Meeting, Chicago, Illinois, USA (September 8-13, 1985).
6. Annual Conference of Pakistani Scientists and Engineers of North America, Dallas, Texas, USA (May, 1985). “Malignant Melanoma Cell Surface Antigen from G-361 Cell Line”.
7. International Conference of Plant Scientists, University of Peshawar 1988). “Isolation and Separation of Essential Oil from Teucrium royleanum”.
8. 3rd National Polymer Science Symposium Baragali (August 27, to September 1, 1989). “Monoclonal Antibodies; Their Production Purification and Applications”.
9. First National Chemistry Conference (October 8-10, 1989). “Hybridoma Technology: A Useful Biotehcnological Tool for Medical and Chemical Sciences”.
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10. First National Chemistry Conference University of Peshawar (October 8-10, 1989). “The Photochemistry of Alkyl Benozohydroxamates”.
11. Second National Chemistry Conference, University of Karachi (December 21-24, 1990). “Syntheses and Physical Organic Investigations of Benzohydroximoyl Cyanides”.
12. International Workshop on “Protein Sequencing” HEJ Research Institute of Chemistry, University of Karachi (December 1-10, 1989).
13. International Symposium on “Protein Structure Function Relationship” HEJ Research Institute of Chemistry, University of Karachi (December 11-14, 1989).
14. National Workshop on “Theoretical and Computational Chemistry” National Academy of Higher Education University Grants Commission, Pakistan (February 6-11, 1993).
15. Training Course in “Frontier Areas of Organic Synthesis” Sponsored by United Nations Industrial Organization (UNIDO)” and International Centre for Sceince and High Technology (ICS) and Held at the “Indian Institute of Science” and Jawahar Lal Nehru Centre for Advanced Scientific Research, Banglore, India from December 8 to December 18, 1993).
16. Invited Speaker in Pakistan-Bangladesh-Iran International Seminar on Analytical Sciences organized by the National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, Pakistan ( December 8-9, 2003).
17. Training Course “ Chemical Safety and Security Officer (CSSO)” sponsored and organized by the Sandia National Labs, Albaqurque, New Mexico, USA in collaboration with the Higher Education Commission, Pakistan , March 29 to April 02, 2010 , Bangkok, Thailand.
Workshops/Symposia/Conferences Organized
1. Organized Workshops on “Spectroscopic Techniques” at Baragali Campus, in 1994 and 1999.
2. Organizing Secretary, First National Chemistry Conference at the University of Peshawar, 1989.
3. Coordinator, First International Chemistry Conference and 11th National Chemistry Conference, April 2001.
4. Secretary, First National Symposium on Analytical and Environmental Chemistry at Baragali, 1992.
Membership& Positions
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(a) Member, American Chemical Society (ACS).
(b) Member, Association of Pakistan Scientists and Engineer of North America (APSENA).
(c) Member, Chemical Society of Pakistan.
(d) Executive Member ,Association of Scientists and Scientific Profession of Pakistan (ASSPP).