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Program is tentative; times & topics may change Page 1 CSRS 43 rd Annual Meeting December 3 - 5, 2015 Manchester Grand Hyatt Hotel San Diego, CA Program Chairs – Zoher Ghogawala, MD & Rick C. Sasso, MD President – Alan S. Hilibrand, MD Revised 10-2-15 Thursday, Dec 3, 2015 Seaport Ballrooms FGH 7:00–7:10 am Welcome and Announcements Zoher Ghogawala, MD and Rick C. Sasso, MD 7:117:59 am Session I: MYELOPATHY Moderators: Ronald A. Lehman, Jr., MD and Thomas A. Zdeblick, MD 7:11–7:17 am Presentation #1 Is Preoperative Duration of Symptoms a Significant Predictor of Functional Status and Quality of Life Outcomes in Patients Undergoing Surgery for the Treatment of Degenerative Cervical Myelopathy? Lindsay Tetreault, HBSc; Branko Kopjar, MD, PhD; Paul M. Arnold, MD; Michael G. Fehlings, MD, PhD 7:18–7:24 am Presentation #2 Laminoplasty Versus Laminectomy and Fusion to Treat Cervical Spondylotic Myelopathy: Outcomes of the Prospective Multicenter Aospine North America and International CSM Studies Carlo Santaguida, MD; Michael G. Fehlings, MD, PhD; Branko Kopjar, MD, PhD; Paul M. Arnold, MD; Helton Defino, MD; Shashank Kale, MD; S. Tim Yoon, MD, PhD; Giuseppe Barbagallo, MD; Ronald Bartels, MD, PhD; Qiang Zhou, MD; Alexander R. Vaccaro, III, MD, PhD 7:25–7:31 am Presentation #3 Clinical Outcome of Cervical Laminoplasty and Postoperative Radiological Change for Cervical Myelopathy with Degenerative Spondylolisthesis Akinobu Suzuki, MD, PhD; Koji Tamia, MD; Hidetomi Terai, MD, PhD; Masatoshi Hoshino, MD, PhD; Hiromitsu Toyoda; Sho Dohzono, MD; Shinji Takahashi, MD; Kazunori Hayashi, MD; Hiroaki Nakamura, MD 7:32–7:38 am Presentation #4 Cervical Anterolisthesis is a Significant Poor Predictor of Neurologic Outcomes in Patients with Cervical Spondylotic Myelopathy following Cervical Laminoplasty Takeshi Oichi, MD; Yasushi Oshima, MD, PhD; Yuki Taniguchi, MD, PhD; Yoshitaka Matsubayashi, MD; Hirotaka Chikuda, MD, PhD; Katsushi Takeshita, MD, PhD; Sakae Tanaka, MD, PhD 7:39–7:45 am Presentation #5 Physical Signs and Clinical Features of Elderly Patients with Cervical Myelopathy: Comparison of 3 Different Age Groups in 100 Consecutive Operative Cases Takahiko Hamasaki, MD 7:46–7:59 am Discussion 8:008:48 am Session II: ECONOMICS/VALUE Moderators: Robert F. Heary, MD and John M. Rhee, MD 8:00–8:06 am Presentation #6 Cost Effectiveness of Operative Vs. Non-Operative Treatment of Geriatric Type-II Odontoid Fracture Daniel R. Barlow, MS; Brendan T. Higgins, MD, MS; Elissa Ozanne, PhD; Anna N. A. Tosteson, ScD; Adam M. Pearson, MD, MS 8:07–8:13 am Presentation #7 Cost Utility Analysis of Anterior Cervical Discectomy and Fusion for Degenerative Spine Disease in Elderly Population Silky Chotai, MD; Scott L. Parker, MD; J. Alex Sielatycki, MD; Ahilan Sivaganesan, MD; Harrison F. Kay, BS; Joseph B. Wick, BA; Matthew J. McGirt, MD; Clinton J. Devin, MD
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Page 1: CSRS 43rd Annual Meeting December 3 - 5, 2015 · PDF fileCost Effectiveness of Operative Vs. Non-Operative Treatment of Geriatric Type-II Odontoid Fracture : Daniel R. Barlow, MS;

Program is tentative; times & topics may change Page 1

CSRS 43rd Annual Meeting

December 3 - 5, 2015 Manchester Grand Hyatt Hotel

San Diego, CA

Program Chairs – Zoher Ghogawala, MD & Rick C. Sasso, MD

President – Alan S. Hilibrand, MD

Revised 10-2-15 Thursday, Dec 3, 2015

Seaport Ballrooms FGH 7:00–7:10 am Welcome and Announcements

Zoher Ghogawala, MD and Rick C. Sasso, MD 7:11–7:59 am Session I: MYELOPATHY Moderators: Ronald A. Lehman, Jr., MD and Thomas A. Zdeblick, MD 7:11–7:17 am Presentation #1

Is Preoperative Duration of Symptoms a Significant Predictor of Functional Status and Quality of Life Outcomes in Patients Undergoing Surgery for the Treatment of Degenerative Cervical Myelopathy? Lindsay Tetreault, HBSc; Branko Kopjar, MD, PhD; Paul M. Arnold, MD; Michael G. Fehlings, MD, PhD

7:18–7:24 am Presentation #2

Laminoplasty Versus Laminectomy and Fusion to Treat Cervical Spondylotic Myelopathy: Outcomes of the Prospective Multicenter Aospine North America and International CSM Studies Carlo Santaguida, MD; Michael G. Fehlings, MD, PhD; Branko Kopjar, MD, PhD; Paul M. Arnold, MD; Helton Defino, MD; Shashank Kale, MD; S. Tim Yoon, MD, PhD; Giuseppe Barbagallo, MD; Ronald Bartels, MD, PhD; Qiang Zhou, MD; Alexander R. Vaccaro, III, MD, PhD

7:25–7:31 am Presentation #3

Clinical Outcome of Cervical Laminoplasty and Postoperative Radiological Change for Cervical Myelopathy with Degenerative Spondylolisthesis Akinobu Suzuki, MD, PhD; Koji Tamia, MD; Hidetomi Terai, MD, PhD; Masatoshi Hoshino, MD, PhD; Hiromitsu Toyoda; Sho Dohzono, MD; Shinji Takahashi, MD; Kazunori Hayashi, MD; Hiroaki Nakamura, MD

7:32–7:38 am Presentation #4

Cervical Anterolisthesis is a Significant Poor Predictor of Neurologic Outcomes in Patients with Cervical Spondylotic Myelopathy following Cervical Laminoplasty Takeshi Oichi, MD; Yasushi Oshima, MD, PhD; Yuki Taniguchi, MD, PhD; Yoshitaka Matsubayashi, MD; Hirotaka Chikuda, MD, PhD; Katsushi Takeshita, MD, PhD; Sakae Tanaka, MD, PhD

7:39–7:45 am Presentation #5

Physical Signs and Clinical Features of Elderly Patients with Cervical Myelopathy: Comparison of 3 Different Age Groups in 100 Consecutive Operative Cases Takahiko Hamasaki, MD

7:46–7:59 am Discussion 8:00–8:48 am Session II: ECONOMICS/VALUE Moderators: Robert F. Heary, MD and John M. Rhee, MD 8:00–8:06 am Presentation #6

Cost Effectiveness of Operative Vs. Non-Operative Treatment of Geriatric Type-II Odontoid Fracture Daniel R. Barlow, MS; Brendan T. Higgins, MD, MS; Elissa Ozanne, PhD; Anna N. A. Tosteson, ScD; Adam M. Pearson, MD, MS

8:07–8:13 am Presentation #7

Cost Utility Analysis of Anterior Cervical Discectomy and Fusion for Degenerative Spine Disease in Elderly Population Silky Chotai, MD; Scott L. Parker, MD; J. Alex Sielatycki, MD; Ahilan Sivaganesan, MD; Harrison F. Kay, BS; Joseph B. Wick, BA; Matthew J. McGirt, MD; Clinton J. Devin, MD

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Program is tentative; times & topics may change Page 2

8:14–8:20 am Presentation #8

Determining the Drivers of Cost for Elective Anterior Cervical Discectomy and Fusion for Cervical Degenerative Disease Silky Chotai, MD; Ahilan Sivaganesan, MD; Scott L. Parker, MD; Aaronson Oran, MD; Joseph Cheng, MD; Matthew J. McGirt, MD; Clinton J. Devin, MD

8:21–8:27 am Presentation #9

Where do True Cost Savings Exist following Elective Surgery for Degenerative Spine Disease? Silky Chotai, MD; Scott L. Parker, MD; Ahilan Sivaganesan, MD; David P. Stonko, BS, MS; Matthew J. McGirt, MD; Clinton J. Devin, MD

8:28–8:34 am Presentation #10

Impact of Obesity on Cost per Quality Adjusted Life Years Gained following Anterior Cervical Discectomy and Fusion in Elective Degenerative Pathology Silky Chotai, MD; J. Alex Sielatycki, MD; Ahilan Sivaganesan, MD; Scott L. Parker, MD; Harrison F. Kay, BS; Kevin R. O’Neill, MD; Matthew J. McGirt, MD; Clinton J. Devin, MD

8:35–8:48 am Discussion 8:49–9:37 am Session III: ARTHROPLASTY Moderators: Justin S. Smith, MD, PhD and Jack E. Zigler, MD 8:49–8:55 am Presentation #11

Cost Utility Analysis of the Cervical Artificial Disc versus Fusion for the Treatment of Two-Level Symptomatic Degenerative Disc Disease: 5 Year Follow-Up Jared D. Ament, MD, MPH; Zhuo Yang, MSc; Pierce D. Nunley, MD; Marcus Stone, PhD; Kee D. Kim, MD

8:56–9:02 am Presentation #12

Seven-Year Cost-Effectiveness of Cervical Disc Replacement versus Anterior Cervical Discectomy and Fusion – Results from Investigational Device Exemption and Post-Approval Studies of Prodisc®-C Total Disc Replacement Kristen E. Radcliff, MD; Jason H. Lerner, PT, MBA, MSc; Thierry Bernard, MS; Chao Yang, MD; Jack E. Zigler, MD

9:03–9:09 am Presentation #13

Comparison of One and Two-Level Treatment with Cervical Disc Arthroplasty or Anterior Cervical Discectomy and Fusion through Five-Year Follow-Up Scott L. Blumenthal, MD; Michael S. Hisey, MD; Hyun W. Bae, MD; Jack E. Zigler, MD

9:10–9:16 am Presentation #14

The Positive Effect of Continued Motion of a Cervical Artificial Disc Replacement on Radiographic Adjacent Level Degeneration at 7 Year Follow-Up Jeffrey M. Spivak, MD; Jack E. Zigler, MD; Michael E. Janssen, DO; Bruce V . Darden, II, MD; Kristen E. Radcliff, MD

9:17–9:23 am Presentation #15

Cervical Total Disc Replacement and Anterior Cervical Discectomy and Fusion have Similar Short-Term Complication Rates Bryce A. Basques, MD; Adam M. Lukasiewicz, MSc; Matthew L. Webb, AB; Andre M. Samuel, BBA; Daniel D. Bohl, MD, MPH; Junyoung Ahn, BS; Jason O. Toy, MD; Kern Singh, MD; Jonathan N. Grauer, MD

9:24–9:37 am Discussion 9:38–10:03 am Break Exhibit Hall in Seaport Ballrooms ABCD 10:04–10:52 am Session IV: BASIC SCIENCE Moderators: Sanford E. Emery, MD, MBA and Jonathan N. Grauer, MD 10:04–10:10 am Presentation #16

Total Disc Replacement using Tissue-Engineered Intervertebral Discs: In Vivo Outcome in a Canine Model. Yu Moriguchi, MD, PhD; Jorge Mojica-Santiago, BS; Peter Grunert, MD; Rodrigo Navarro-Ramirez, MD, MSc; Thamina Khair, BA; Brenton Pennicooke, MD, MS; Connor Berlin, BS; Lawrence J. Bonassar, PhD; Roger Härtl, MD

10:11–10:17 am Presentation #17

Cervical Intervertebral Disc and Paraspinal Muscle Deconditioning following Long-Duration Spaceflight and 30-Day Recovery Jacquelyn A. Holt; Robert M. Healey, BS, MBA; Brandon R. Macias, PhD; Alan R. Hargens, PhD; Jeffrey C. Lotz, PhD; Douglas G. Chang, MD, PhD

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10:18–10:24 am Presentation #18

Transplantation of Human IPS Cell-Derived Oligodendrocyte Precursor Cells Enriched Neural Stem/Progenitor Cells in Chronic and Subacute Spinal Cord Injury Soya Kawabata, MD; Akio Iwanami, MD, PhD; Jun Koyama, MD, PhD; Morito Takano, MD, PhD; Yuko Numasawa, MD, PhD; Go Itakura, MD, PhD; Yoshiomi Kobayashi, MD, PhD; Shinsuke Shibata, MD, PhD; Hideyuki Okano, MD, PhD; Morio Matsumoto, MD, PhD; Masaya Nakamura, MD, PhD

10:25–10:31 am Presentation #19

Altered Forelimb Neural Circuitry Associated with Impaired Manual Dexterity in Cervical Spondylotic Myelopathy (CSM) Kajana Satkunendrarajah, PhD; Spyridon K. Karadimas, MD, PhD; Michael G. Fehlings, MD, PhD

10:32–10:38 am Presentation #20

Evaluation of Vancomycin Powder on Bone Healing in a Rat Spinal Arthrodesis Model Marco C. Mendoza, MD; Kevin A. Sonn, MD; Abhishek S. Kannan, BS; Sharath Bellary, MD; Sean M. Mitchell, BS; Gurmit Singh, BS; Christian Park, BS; Chawon Yun, PhD; Anjan Ghosh; Stuart R. Stock, PhD; Erin L. Hsu, PhD; Wellington K. Hsu, MD * Vancomycin

10:39–10:52 am Discussion 10:53–10:58 am Special Projects Committee Report Cervical Radiculopathy: Assessment of Clinical Outcomes and Cost-effectiveness of Operative

and Non-operative Treatment Zoher Ghogawala, MD; Jonathan N. Grauer, MD; James S. Harrop, MD; Alan S. Hilibrand, MD; Jeffery A. Rihn, MD

10:59–11:04 am Special Projects Committee Report Review of Cervical Myelopathy Evidence and Clinical Guideline Development

Michael G. Fehlings, MD, PhD 11:05–11:07 am Discussion 11:08 am-12:10 pm Highlighted Poster Presentations I Moderators: Todd J. Albert, MD and Alexander R. Vaccaro, III, MD, PhD 11:08–11:28 am Outcomes: 11:08-11:10 am Presentation #21 P

Return to Work Rates after Single Level Cervical Fusion Surgery for Degenerative Disc Disease Compared to Fusion for Radiculopathy in Workers’ Compensation Setting. Mhamad Faour, MD; Joshua T. Anderson, BS; Uri M. Ahn, MD; Nicholas U. Ahn, MD

11:11-11:13 am Presentation #22 P

Does Depression or Anxiety affect Patient-Reported Outcomes and Satisfaction following Operative Treatment for Cervical Myelopathy or Radiculopathy? Harrison F. Kay, BS; Silky Chotai, MD; Joseph B. Wick, BA; David P. Stonko, MS; Matthew J. McGirt, MD; Clinton J. Devin, MD

11:14-11:16 am Presentation #23 P

The Profile of a Smoker and its Impact on Outcomes after Cervical Spine Surgery Raul A. Vasquez-Castellanos, MD; Silky Chotai, MD; Joseph B. Wick, BA; David P. Stonko, BS, MS; Joseph S. Cheng, MD, MS; Clinton J. Devin, MD; Anthony L. Asher, MD; Matthew J. McGirt, MD

11:17-11:19 am Presentation #24 P

Patient-Specific Factors Predicting Dissatisfaction after Elective Surgery for Degenerative Spine Diseases Sheyan J. Armaghani, MD, Silky Chotai, MD; Ahilan Sivaganesan, MD; Scott L. Parker, MD; J. Alex Sielatycki, MD; David P. Stonko, BS, MS; Matthew J. McGirt, MD; Clinton J. Devin, MD

11:20-11:22 am Presentation #25 P

Clinical Obesity in Total Disc Replacement and Anterior Cervical Discectomy and Fusion Patients through Five Years Follow-Up Todd J. Albert, MD; Domagoj Coric, MD; Han Jo Kim, MD; Elizabeth Roensch, BS; Kyle Marshall, BS; Kristen E. Radcliff, MD

11:23-11:28 am Discussion 11:29-11:49 am Spinal Cord Injury: 11:29-11:31 am Presentation #26 P

Classifying Injury Severity and Predicting Neurologic Outcome after Acute Human Spinal Cord Injury with Cerebrospinal Fluid Biomarkers. Brian K. Kwon, MD, PhD; Femke Streijger, PhD; Nader Fallah, PhD; Scott Paquette, MD, MEd; John Street, MD, PhD; Charles G. Fisher, MD, MPH; Marcel F. Dvorak, MD

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11:32-11:34 am Presentation #27 P

Functional Assessment of Local Versus Distal Transplantation of Human Neural Stem Cells following Chronic Spinal Cord Injury Ivan Cheng, MD; Michael Githens, MD; Tyler Johnston, MD; R. Lane Smith, PhD * Neural stem cells

11:35-11:37 am Presentation #28 P

Intrathecal Administration of Recombinant Human Hepatocyte Growth Factor for Acute Spinal Cord Injury: Road from Bench to Clinical Trial and Future Perspective Kazuya Kitamura, MD, PhD; Akio Iwanami, MD, PhD; Hiroki Iwai, MD, PhD; Jun-ichi Yamane, MD, PhD; Kanehiro Fujiyoshi, MD; Yoshiaki Toyama, MD; Morio Matsumoto, MD, PhD; Hideyuki Okano; Masaya Nakamura, MD

11:38-11:40 am Presentation #29 P

Preexisting Severe Cervical Spinal Cord Compression is a Significant Risk Factor for Developing Severe Paralysis in Patients with Traumatic Cervical Spinal Cord Injury without Bone Injury: A Retrospective Cohort Study

Takeshi Oichi, MD; Yasushi Oshima, MD, PhD; Rentaro Okazaki, MD, PhD; Seiichi Azuma, MD 11:41-11:43 am Presentation #30 P

Defining Central Cord Syndrome: Does Neurology or Injury Morphology Provide Better Discrimination of Neurological Outcomes? Jérôme Paquet, MD; Vanessa K. Noonan; Brian K. Kwon, MD, PhD; Eve C. Tsai, MD, PhD; Sean Christie, MD; Carly S. Rivers, PhD; Henry Ahn, MD; Najmedden Attabib, MD; Christopher S. Bailey, MD; Brian Drew, MD; Michael G. Fehlings, MD, PhD; Joel A. Finkelstein, MD; Daryl R. Fourney, MD; R. John Hurlbert, MD, PhD; Stefan Parent, MD; Marcel F. Dvorak, MD

11:44-11:49 am Discussion 11:50 am-12:10 pm OccipitoCervical Junction: 11:50-11:52 am Presentation #31 P

Vertebral Artery Course for Occipital Condyle Screw Fixation Ho Jin Lee, MD; Jae Taek Hong, MD, PhD

11:53-11:55 am Presentation #32 P

Minimum 5-Year Follow-Up Results for Occipitocervical Fusion Using the Screw-Rod System in Craniocervical Instability Kei Ando, MD; Shiro Imagama, MD, PhD; Naoki Ishiguro MD, PhD

11:56-11:58 am Presentation #33 P

Accurate and Simple Screw Insertion Procedure with Patient-Specific Screw Guide Templates for Posterior C1-C2 Fixation Taku Sugawara, MD, PhD; Shuichi Kaneyama, MD, PhD; Masatoshi Sumi, MD, PhD

11:59 am-12:01 pm Presentation #34 P

Subaxial Cervical Sagittal Alignment Following C1-C2 Fusion For Atlanto-Axial Osteoarthritis Daniel G. Kang, MD; Ronald A. Lehman, Jr., MD; Scott C. Wagner, MD; K. Daniel Riew, MD

12:02-12:04 pm Presentation #35 P

The Pathomechanisms of Dysphagia after Occipitospinal Fusion - Kinematic Analysis by Videofluoroscopic Swallowing Study Shuichi Kaneyama, MD, PhD; Masatoshi Sumi, MD, PhD; Koichi Kasahara, MD, PhD; Aritetsu Kanemura, MD, PhD; Masato Takabatake, MD; Akihiro Koh, MD; Hiroaki Hirata, MD, PhD

12:05-12:10 pm Discussion 12:11–1:11 pm Non-Member Lunch Seaport Ballrooms ABCD 12:11–1:11 pm Member Lunch Balboa ABC 1:12–1:59 pm Session V: RESEARCH SESSION Moderator: John M. Rhee, MD 1:12–1:28 pm Announcement of 2015 ~ 21st Century Premier Donor Research Grant Winners 21st Century Research and Education Grants Seed Starter Research and Education Grants Resident Fellow Research and Education Grants 1:29–1:30 pm Introduction – Research Grant Updates

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21st Century Research and Education Grant 1:31–1:36 pm The Effects of Peri-Operative Steroids on Dysphagia following Anterior Cervical Spine

Surgery: A Randomized, Prospective, Double-Blind Study Sanford E. Emery, MD, MBA, John C. France, MD, Scott D. Daffner, MD

1:37–1:42 pm Chemokine-Directed Homing of Peripheral Blood Mobilized Stem Cells to Enhance Cervical

Spine Fusion Kevin C. Baker, PhD; Daniel K. Park, MD; Jeffrey S. Fischgrund, MD

Seed Starter Grants 1:43–1:48 pm Can Human Mesenchymal Stem Cells Prevent or “Rescue” Intervertebral Disc Cells from the

Inflammatory Changes Associated with Disc Degeneration? Christopher K. Kepler, MD, MBA; D. Greg Anderson, MD; Dessislava Z. Markova, PhD; John D. Koerner, MD

1:49-1:54 pm Disc Regeneration: Evaluation of Growth and Differentiation Factor-5 (GDF-5; BMP14)

Production and Expression Pathways in Human Disc Cells Exposed to Proinflammatory Cytokines Helen E. Gruber, PhD; James H. Norton, PhD; Edward N. Hanley, Jr., MD

1:55–2:05 pm Discussion 2:06–2:54 pm Session VI: COMPLICATIONS Moderators: Bobby K. Tay, MD and James S. Harrop, MD 2:06–2:12 pm Presentation #36

Does the Timing of Pre-Operative Epidural Steroid Injection affect Infection Risk after ACDF or Posterior Cervical Fusion? Jourdan M. Cancienne, MD; Brian C. Werner, MD; Anuj Singla, MD; Hamid Hassanzadeh, MD; Frank H. Shen, MD; Adam L. Shimer, MD

2:13–2:19 pm Presentation #37

Is Obesity Correlated with Increased Complications following Cervical Surgery for Degenerative Conditions? John A. Sielatycki, MD; Silky Chotai, MD; David P. Stonko, BS, MS; Joseph B. Wick, BA; Harrison F. Kay, BS; Kevin R. O’Neill, MD, MS; Clinton J. Devin, MD

2:20–2:26 pm Presentation #38

Complications of Iliac Crest Bone Graft in Cervical Spine Surgery M. Leslie Golden, BA, MD; Steven K. Leckie, MD; John G. Heller, MD

2:27–2:33 pm Presentation #39

Does the Use of Intrawound Vancomycin Decreases the Risk of Surgical Site Infection after Elective Spine Surgery? – A Multicenter Analysis Clinton J. Devin, MD; Alexander R. Vaccaro, III, MD, PhD; Matthew J. McGirt, MD; Silky Chotai, MD; Jim A. Youssef, MD; Douglas G. Orndorff, MD; Paul M. Arnold, MD; Anthony K. Frempong-Boadu, MD; Isador H. Lieberman, MD, MBA; Hirad Hedayat, MD; Charles L. Branch, Jr., MD; Jeffrey C. Wang, MD; Robert E. Isaacs, MD; Kristen E. Radcliff, MD; Joshua C. Patt, MD; Kristen R. Archer, MD

2:34–2:40 pm Presentation #40

Recurrent Laryngeal Nerve Palsy after Cervical Spine Surgery – A Multicenter Study Ziya L. Gokaslan, MD; Mohamad Bydon, MD; Jay Won Rhee, MD; Rafael D. De la Garza-Ramos, MD; Zachary A. Smith, MD; Wellington K. Hsu, MD; Sheeraz A. Qureshi, MD, MBA; Samuel K. Cho, MD; Evan O. Baird, MD; Thomas E. Mroz, MD; Michael G. Fehlings, MD, PhD; Paul M. Arnold, MD; K. Daniel Riew, MD

2:41–2:54 pm Discussion 2:55–3:25 pm Break Exhibit Hall in Seaport Ballrooms ABCD 3:26–4:27 pm Introduction of Henry H. Bohlman Presidential Guest Speaker – Alan S. Hilibrand, MD Henry H. Bohlman Presidential Guest Lecture – Charles Krauthammer, MD 4:14–4:27 pm Discussion 4:28–5:16 pm Session VII: DIAGNOSTICS Moderators: Louis G. Jenis, MD and Joseph R. O'Brien, MD, MPH

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4:28–4:34 pm Presentation #41

Predictive Risk Factors of Cervical Spine Instabilities in Rheumatoid Arthritis: A Prospective Minimum 10-Year Multicenter Cohort Study Yoshiki Terashima, MD; Takashi Yurube, MD, PhD; Hiroaki Hirata, MD, PhD; Daisuke Sugiyama, MD, PhD; Masatoshi Sumi, MD, PhD

4:35–4:41 pm Presentation #42

Morbidity Rate and Risk Factors of Cervical Lesions in Rheumatoid Arthritis Patients under Current Pharmacological Treatment Paradigm Takashi Kaito, MD, PhD; Hiroyasu Fujiwara, MD; Takahiro Makino, MD, DMSc; Masafumi Kashii, MD, PhD; Yusuke Sakai, MD; Kazuo Yonenobu, MD, DMSc

4:42–4:48 pm Presentation #43

Prevalence and Imaging Characteristics of Asymptomatic and Symptomatic Spondylotic Cervical Spinal Cord Compression in General Population Josef Bednarik, MD, PhD; Miloš Kerkovský, MD, PhD; Zdenek Kadanka, MD, PhD; Zdenek Kadanka, Jr., MD; Ivana Kovalová; Barbora Jakubcová

4:49–4:55 pm Presentation #44

What is the Most Accurate Radiographic Anterior Cervical Fusion Criteria? Kwang-Sup Song, MD; K. Daniel Riew, MD

4:56–5:02 pm Presentation #45

Circulating MicroRNAs Reflect Neural Dysfunction in Patients with Cervical Spondylotic Myelopathy: Implications for a Novel Biomarker of Disease Pathobiology Alex Laliberte, MSc; Spyridon K. Karadimas, MD, PhD; Sukhvinder K. Kalsi-Ryan, BScPT, MSc, PhD; Aria Nouri, MD; Eric M. Massicotte, MD; Michael G. Fehlings, MD, PhD

5:03–5:16 pm Discussion 5:16 pm Adjourn 5:20–7:20 pm Welcome Reception Exhibit Hall in Seaport Ballrooms ABCD Friday, Dec 4, 2015

Seaport Ballrooms FGH 7:00–7:10 am Welcome and Announcements

Zoher Ghogawala, MD and Rick C. Sasso, MD 7:11–7:59 am Session VIII: ANTERIOR CERVICAL SURGERY Moderators: Paul M. Arnold, MD and Alexander J. Ghanayem, MD 7:11–7:17 am Presentation #46

What is the Fate of the Pseudarthrosis Detected at 1 Year after Anterior Cervical Discectomy and Fusion? Jae Hwan Cho, MD; Jung-Ki Ha, MD; Choon Sung Lee, MD, PhD; Chang Ju Hwang, MD; Sunghun Choi, MD; Chul Gie Hong, MD; Youn-Suk Joo, MD; Dong-Ho Lee, MD, PhD

7:18–7:24 am Presentation #47

ACDF with Total En Bloc Resection of Uncinate in Foraminal Stenosis of the Cervical Spine; Comparison with Conventional ACDF Kyung-Soo Suk, MD, PhD; Hak-Sun Kim, MD, PhD; Seong-Hwan Moon, MD, PhD; Hwan-Mo Lee, MD, PhD; Jae-Ho Lee, MD; Sung-Yub Jin, MD; Pierre M. Mella, MD

7:25–7:31 am Presentation #48

Predictors of Extended Hospital Stay after Cervical Disc Replacement or Anterior Cervical Discectomy and Fusion: Results from 1,004 Patients in an FDA Trial. S. Tim Yoon, MD, PhD; Aaron J. Greenberg, MD; Praveen V. Mummaneni, MD

7:32–7:38 am Presentation #49

Effect of Inclusion of Asymptomatic Spondylotic Levels on Adjacent Segment Disease following ACDF Caleb J. Behrend, MD; Paul W. Millhouse, MD; Vismay Thakkar, MD; Alexander R. Vaccaro, III, MD, PhD; Alan S. Hilibrand, MD; Todd J. Albert, MD

7:39–7:45 am Presentation #50

Adjacent Segment Range of Motion does not Increase 2-Years after Single-Level Cervical Arthrodesis William Anderst, PhD; Tyler West; William F. Donaldson, III, MD; Joon Yung Lee, MD; James D. Kang, MD

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7:46–7:59 am Discussion 8:00–8:48 am Session IX: DYSPHAGIA Moderators: Howard S. An, MD and Ronald I. Apfelbaum, MD 8:00–8:06 am Presentation #51

Prospective Comparison of Dysphagia following Anterior Cervical Discectomy and Fusion (ACDF) with and without rhBMP-2. Michael R. Murray, MD; Steven K. Leckie, MD; Bradley W. Moatz, MD; Adam J. Schell, MD; Ajay Premkumar, BS; John G. Heller, MD * Infuse Bone Graft - Medtronic

8:07–8:13 am Presentation #52

Influence of the Neck Postural Change on Cervical Spine Motion and Angle during Swallowing Jun Young Kim, MD; Il Sup Kim, MD, PhD; Yun Hyuk Kim, PhD; Sung Hoon Im, MD; Jae Taek Hong, MD, PhD

8:14–8:20 am Presentation #53

The Effects of Perioperative Steroids on Dysphagia following Anterior Cervical Spine Surgery: A Randomized, Prospective, Double-Blind Study Sanford E. Emery, MD, MBA; John C. France, MD; Scott D. Daffner, MD; Gerald R. Hobbs, PhD

8:21–8:27 am Presentation #54

Impact of Local Intraoperative Steroid Application on Patient-Reported Swallow Function following an Anterior Cervical Discectomy and Fusion: Preliminary Results Junyoung Ahn, BS; Junho Ahn, BS; Daniel D. Bohl, MD, MPH; Ehsan Tabaraee, MD; Gabriel Duhancioglu, MS; Rahul Kamath, MS; Daniel J. Johnson, BS; Dustin H. Massel, BS; Kern Singh, MD

8:28–8:34 am Presentation #55

The Effect of Local Intraoperative Steroid Administration on the Rate of Post-Operative Dysphagia Following ACDF: A National Database Study of 245,754 Patients Jourdan M. Cancienne, MD; Brian C. Werner, MD; Anuj Singla, MD; Hamid Hassanzadeh, MD; Frank H. Shen, MD; Adam L. Shimer, MD

8:35–8:48 am Discussion 8:49-8:54 am Introduction of CSRS President - Robert F. Heary, MD 8:55–9:25 am PRESIDENTIAL ADDRESS - Alan S. Hilibrand, MD 9:26-9:56 am Break Exhibit Hall in Seaport Ballrooms ABCD 9:57–10:45 am Session X: MYELOPATHY II Moderators: Jacob M. Buchowski, MD, MS and Christopher I. Shaffrey, MD 9:57–10:03 am Presentation #56

The Application of a Novel Sensitive Gait Assessment Method to Optimize the Evaluation of Patients with Degenerative Cervical Myelopathy Sukhvinder K. Kalsi-Ryan, BScPT, MSc, PhD; Alex Laliberte, MSc; Spyridon K. Karadimas, MD, PhD; Eric M. Massicotte, MD; Mohammed Farid Shamji, MD, PhD; Michael G. Fehlings, MD, PhD

10:04–10:10 am Presentation #57

Surgical Decompression in an Experimental Model of Cervical Spondylotic Myelopathy induces a Neuroinflammatory Response: Implications for Perioperative Clinical Management Pia M. Vidal, BS, PhD; Spyridon K. Karadimas, MD, PhD; Antigona Ulndreaj, BA; Stefania Forner, PhD; Alex Laliberte, MSc; Michael G. Fehlings, MD, PhD

10:11–10:17 am Presentation #58

The Fall and Fracture Risk of Medicare Patients with Cervical Myelopathy Daniel J. Blizzard, MD, MS; Michael A. Gallizzi, MD, MS; Charles Sheets, PT; Colin T. Penrose, BA, BS; Robert E. Isaacs, MD; Christopher R. Brown, MD

10:18–10:24 am Presentation #59

Minimum Clinically Important Difference (MCID) of the JOA Score and 10-Second Test in Cervical Myelopathy Disorders Eiji Wada, MD

10:25–10:31 am Presentation #60

The Minimum Clinically Important Difference of the modified Japanese Orthopaedic Association Scale in Patients with Degenerative Cervical Myelopathy Lindsay Tetreault, HBSc; Branko Kopjar, MD; Pierre Cote, DC, PhD; Aria Nouri, MD; Michael G. Fehlings, MD, PhD

10:32–10:45 am Discussion

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10:46–11:34 am Session XI: OUTCOMES Moderators: Mitchel B. Harris, MD and Serena S. Hu, MD 10:46–10:52 am Presentation #61

The Association Between Preoperative Mental Distress and Patient Reported Outcome in Patients Treated Surgically for Cervical Radiculopathy. Martin Skeppholm, MD, PhD; Claes Olerud, MD, PhD

10:53–10:59 am Presentation #62

PROMIS Physical Function: A Better Patient Reported Outcome Measure in Cervical Spine Patients Darrel S. Brodke, MD; Brandon D. Lawrence, MD; W. Ryan Spiker, MD; Ashley M. Neese, BS; Man Hung, PhD

11:00–11:06 am Presentation #63

Outcomes and Complications of Fusions from the Cervical Spine to the Pelvis: Series of 46 Cases with Average 2.7 Year Follow Up Sravisht Iyer, MD; Han-Jo Kim, MD; Alexander A. Theologis, MD; Venu M. Nemani, MD, PhD; Todd J. Albert, MD; Lawrence G. Lenke, MD; Shane Burch, MD; Oheneba Boachie-Adjei, MD; Vedat Deviren, MD; Themistocles S. Protopsaltis, MD; Justin S. Smith, MD, PhD; Justin K. Scheer, BS; Jun Mizutani, MD; Eric O. Klineberg, MD; Christopher P. Ames, MD

11:07–11:13 am Presentation #64

Impact of Adverse Events on Clinical Outcome: Results through Five-Year Follow-Up Michael S. Hisey, MD; Donna D. Ohnmeiss, MD, Dr.Med; Hyun W. Bae, MD; Jack E. Zigler, MD

11:14–11:20 am Presentation #65

Quality of Life and General Health following Elective Surgery for Cervical Spine Pathologies: Determining Valid and Responsive Metric of Heath State Utility Silky Chotai, MD; Scott L. Parker, MD; Ahilan Sivaganesan, MD; John A. Sielatycki, MD; Joseph B. Wick, BA; Matthew J. McGirt, MD; Clinton J. Devin, MD

11:21–11:34 am Discussion 11:35-11:43 am 2015 CSRS North America Traveling Fellowship Report

Themistocles S. Protopsaltis, MD; Kern Singh, MD 11:44–11:49 am Preview CSRS 2016 Annual Meeting in Toronto, Ontario, Canada

Michael G. Fehlings, MD, PhD 11:50–11:55 am Preview CSRS Asia Pacific Section 2016 Annual Meeting in Seoul, Korea

Jin Sup Yeom, MD, PhD 11:56 am–12:01 pm Preview CSRS European Section 2016 Annual Meeting in Prague, Czech Republic

Bengt I. Lind, MD, PhD 12:01 pm Adjourn

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ADDITIONAL REGISTRATION FEE REQUIRED ~ CME ACCREDITED SYMPOSIA Optional Luncheon Programming Friday, Dec 4, 2015 12:30–2:30 pm Myelopathy Session - Open Case Presentation: “Ask the Experts” – Seaport Ballroom E Moderators: K. Daniel Riew, MD and Jin Sup Yeom, MD, PhD 12:30-12:35 pm Introduction - K. Daniel Riew, MD 12:30-1:15 pm Lunch Service 12:36-12:37 pm Case presentations - Rick C. Sasso, MD 12:38-12:48 pm Discussion by panelists 12:49-12:50 pm Case solution - Rick C. Sasso, MD 12:51-12:56 pm Discussion by panelists, audience 12:57-12:58 pm Case presentations - Zoher Ghogawala, MD 12:59-1:09 pm Discussion by panelists 1:10-1:11 pm Case solution - Zoher Ghogawala, MD 1:12-1:17 pm Discussion by panelists, audience 1:18-1:19 pm Case presentations - Alan S. Hilibrand, MD 1:20-1:30 pm Discussion by panelists 1:31-1:32 pm Case solution - Alan S. Hilibrand, MD 1:33-1:38 pm Discussion by panelists, audience 1:39-1:40 pm Case presentations - Michael G. Fehlings, MD, PhD 1:41-1:51 pm Discussion by panelists 1:52-1:53 pm Case solution - Michael G. Fehlings, MD, PhD 1:54-1:59 pm Discussion by panelists, audience 2:00-2:01 pm Case presentations - K. Daniel Riew, MD 2:02-2:12 pm Discussion by panelists 2:13-2:14 pm Case solution - K. Daniel Riew, MD 2:15-2:20 pm Discussion by panelists, audience 2:21-2:30 pm Final comments, questions - K. Daniel Riew, MD

Register online at https://ebus.csrs.org/default.aspx?tabid=164&productid=434

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ADDITIONAL REGISTRATION FEE REQUIRED ~ CME ACCREDITED SYMPOSIA

Optional Dinner Programming Friday, Dec 4, 2015 6:00 –8:15 pm Deformity Session - Open Case Presentations: “Ask the Experts” – Seaport Ballroom E Moderators: Alexander R. Vaccaro, III, MD, PhD and Bengt I. Lind, MD, PhD 6:00-6:05 pm Introduction - Alexander R. Vaccaro, III, MD, PhD 6:00-6:45 pm Dinner Service 6:06-6:13 pm Case presentation 1 - Robert F. Heary, MD, MD 6:14-6:17 pm Discussion by panelists, audience 6:18-6:25 pm Case presentation 2 - Robert F. Heary, MD 6:26-6:29 pm Discussion by panelists, audience 6:30-6:37 pm Case presentation 3 - Jens R. Chapman, MD 6:38-6:41 pm Discussion by panelists, audience 6:42-6:49 pm Case presentation 4 - Jens R. Chapman, MD 6:50-6:53 pm Discussion by panelists, audience 6:54-7:01 pm Case presentation 5 - Kazuhiro Chiba, MD, PhD 7:02-7:05 pm Discussion by panelists, audience 7:06-7:13 pm Case presentation 6 - Kazuhiro Chiba, MD, PhD 7:14-7:17 pm Discussion by panelists, audience 7:18-7:25 pm Case presentation 7 - Paul A. Anderson, MD 7:26-7:29 pm Discussion by panelists, audience 7:30-7:37 pm Case presentation 8 - Paul A. Anderson, MD 7:38-7:41 pm Discussion by panelists, audience 7:42-7:49 pm Case presentation 9 - K. Daniel Riew, MD 7:50-7:53 pm Discussion by panelists, audience 7:54-8:01 pm Case presentation 10 - K. Daniel Riew, MD 8:02-8:05 pm Discussion by panelists, audience 8:06-8:14 pm Final comments, questions - Alexander R. Vaccaro, III, MD, PhD 8:15 pm Adjourn

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Saturday, Dec 5 2015 Seaport Ballrooms FGH

7:00–7:05 am Welcome and Announcements

Zoher Ghogawala, MD and Rick C. Sasso, MD 7:06–7:54 am Session XII: TRAUMA Moderators: Brian K. Kwon, MD, PhD and Kristen E. Radcliff, MD 7:06–7:12 am Presentation #66

Cervical Facet Dislocations in the Pediatric Population: A Report of 21 Cases at a Level 1 Trauma Center from 2004-2014 Alireza K. Anissipour, DO; Carlo Bellabarba, MD; Richard J. Bransford, MD

7:13–7:19 am Presentation #67

Comparison of the Vacuum Mattress Versus the Spine Board Alone for Immobilization of the Cervical Spine Injured Patient: A Biomechanical Cadaveric Study Mark L. Prasarn, MD; Per Kristian Hyldmo, MD; MaryBeth Horodyski, PhD; Glenn R. Rechtine, II, MD

7:20–7:26 am Presentation #68

The Incidence and Associated Risk Factors of Cervical Spine Epidural Hematoma following Adult Trauma Pedro A. Ricart, MD, MS; Ravi Verma, MD, MBA; Steven J. Fineberg, MD; Kyle Fink; David E. Asprinio, MD; Louis F. Amorosa, MD

7:27–7:33 am Presentation #69

Dens Fractures Displacement is Dependent on the Sagittal Alignment of the Subaxial Cervical Spine Rather than the Force of Injury Jung U. Yoo, MD; Sabina R. Blizzard, BA; Natalie L. Zusman, BS; Matthew S. Shinseki, BS; Marcel W. Betsch, MD; Bala Krishnamoorthy, PhD

7:34–7:40 am Presentation #70

Risk Factors for Dysphagia in Acute Cervical Spinal Cord Injury Tetsuo Hayashi, MD, PhD; Takeshi Maeda, MD, PhD; Hiroaki Sakai, MD; Yuichiro Morishita, MD, PhD; Keiichiro Shiba, MD, PhD

7:41–7:54 am Discussion 7:55–8:55 am Symposium I: COMPLICATIONS Moderator: Mitchel B. Harris, MD 7:55–8:04 am Pseudarthrosis

Darren R. Lebl, MD 8:05–8:14 am Pseudarthrosis

Darrel S. Brodke, MD 8:15–8:24 am Discussion 8:25–8:34 am Post-op Dysphagia

John C. France, MD 8:35–8:44 am Post-op Dysphagia

Paul M. Arnold, MD 8:45–8:55 am Discussion 8:56–9:43 am Session XIII: MYELOPATHY III Moderators: Darrel S. Brodke, MD and Bradford L. Currier, MD 8:56–9:02 am Presentation #71

Does Age affect Surgical Outcomes in Patients with Degenerative Cervical Myelopathy?: Results from the Prospective, Multicenter AOSpine International Study in 479 Patients Hiroaki Nakashima, MD; Lindsay Tetreault, HBSc; Narihito Nagoshi, MD, PhD; Aria Nouri, MD; Michael G. Fehlings, MD, PhD

9:03–9:09 am Presentation #72

A Clinical Prediction Rule for Functional Outcomes in Patients Undergoing Surgery for Severe Degenerative Cervical Myelopathy: Analysis of an International Prospective Multicentre Dataset of 254 Subjects Lindsay Tetreault, HBSc; Branko Kopjar, MD; Pierre Cote, DC, PhD; Paul M. Arnold, MD; Michael G. Fehlings, MD, PhD

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9:10–9:16 am Presentation #73

Signal Intensity Ratio on Magnetic Resonance Imaging and Neurological Status as Prognostic Factors in Patients with Cervical Compressive Myelopathy Jun Jae Shin, MD, PhD

9:17–9:23 am Presentation #74

Clinical Outcomes following Surgical Management of Coexistent Parkinson’s Disease and Cervical Stenosis with Myelopathy Roy Xiao, BA; Jacob A. Miller, BS; Daniel Lubelski, MD; Thomas E. Mroz, MD; Edward C. Benzel, MD; Ajit A. Krishnaney, MD; Andre Machado, MD, PhD

9:24–9:30 am Presentation #75

Symptomatic Lumbar Spinal Stenosis Increases the Risk of Spondylotic Cervical Spinal Cord Compression and Cervical Spondylotic Myelopathy. Josef Bednarik, MD, PhD; Blanka Adamova, MD, PhD; Miloš Kerkovský, MD, PhD; Ivana Kovalová; Zdenek Kadanka, Jr., MD; Zdenek Kadanka, MD, PhD

9:31–9:44 am Discussion 9:45–9:49 am Announcement of Poster Award Winners 9:50–9:55 am Presentation of CSRS Medallion to Robert F. Heary, MD 9:56–10:11 am BREAK Seaport Ballroom Foyer 10:12–11:00 am Session XIV: DEFORMITY Moderators: Ivan Cheng, MD and Jeffrey D. Coe, MD 10:12–10:18 am Presentation #76

Variations in Sagittal Alignment Parameters Based on Age: A Prospective Study of Normal Patients using EOS Imaging Sravisht Iyer, MD; Lawrence G. Lenke, MD; Venu M. Nemani, MD, PhD; Michael C. Fu, MD; Grant D. Shifflett, MD; Todd J. Albert, MD; Brenda A. Sides, MA; Lionel N. Metz, MD; Matthew E. Cunninghami, MD, PhD; Han-Jo Kim, MD

10:19–10:25 am Presentation #77

Cervical Deformity Surgery does not Result in Acute Post-Operative Dysphagia: Preliminary Results from a Prospective Cervical Deformity Study Han-Jo Kim, MD; Sravisht Iyer, MD; Justin S. Smith, MD, PhD; Michael P. Kelly, MD; Michael F. O'Brien, MD; Munish C. Gupta, MD; Todd J. Albert, MD; Themistocles S. Protopsaltis, MD; Gregory M. Mundis, MD; Peter G. Passias, MD; Eric O. Klineberg, MD; Christopher P. Ames, MD; International Spine Study Group

10:26–10:32 am Presentation #78

Cervical Kyphosis does not Imply Cervical Deformity: Predicting Cervical Curvature Required for Horizontal Gaze Based on Spinal Global Alignment and Thoracic Kyphosis Bassel G. Diebo, MD; Jonathan H. Oren, MD; Matthew A. Spiegel, BA; Shaleen Vira, MD; Elizabeth M. Tanzi, NP; Barthelemy Liabaud; Renaud Lafage, MS; Jensen K. Henry, BA; Themistocles S. Protopsaltis, MD, Thomas J. Errico, MD; Frank J. Schwab, MD; Virginie C. Lafage, PhD

10:33–10:39 am Presentation #79

Does Spinopelvic Alignment Change after Cervical Laminoplasty in Patients with Cervical Spondylotic Myelopathy? Jun Ouchida; Yasutsugu Yukawa, MD, PhD; Masaaki Machino, MD

10:40–10:46 am Presentation #80

Changes in Sagittal Cervical Alignment after Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis: An Evaluation of 141 Patients Joshua M. Pahys, MD; Jahangir K. Asghar, MD; Alexander A. Theologis, MD; Suken A. Shah, MD; Patrick J. Cahill, MD; Amer F. Samdani, MD; Christopher P. Ames, MD

10:47–11:00 am Discussion 11:01 am–12:13 pm Highlighted Poster Presentations II Moderators: Pasquale X. Montesano, MD and Thomas M. Reilly, MD 11:01-11:24 am Surgical Techniques: 11:01-11:03 am Presentation #81 P

540° Cervical Realignment Procedure for Extensive Cervical OPll with Kyphotic Deformity Sang-Hun Lee, MD, PhD; Ki-Tack Kim, MD; Jung-Hee Lee, MD; Kyung-Chung Kang; Sang-Phil Hwang, MD; Soo-Jin Jang, MD * Cervical lateral mass screw, cervical pedicle screw

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11:04-11:06 am Presentation #82 P

Regional Thoracic and Lumbar Sagittal Cobb Angle Changes and UIV Determine Evolution of Cervical Alignment after ASD Surgery: Series of 171 Patients with 2 Year Follow Up Brian J. Neuman, MD; Amit Jain, MD; Daniel M. Sciubba, MD; Eric O. Klineberg, MD; Han Jo Kim, MD; Luke P. Zebala, MD; Gregory M. Mundis, MD; Virginie C. Lafage, PhD; Peter G. Passias, MD; Renaud Lafage, MS; Themistocles S. Protopsaltis, MD; D. Kojo Hamilton; Justin K. Scheer, BS; Christopher P. Ames, MD; International Spine Study Group

11:07-11:09 am Presentation #83 P

Are Collapsed Cervical Discs Amenable to Total Disc Arthroplasty? Analysis of Prospective Clinical Study Results With 2-Year Follow-Up Avinash G. Patwardhan, PhD; Gerard Carandang, MS; Leonard I. Voronov, PhD; Robert M. Havey, BS; Gary Paul; Carl Lauryssen, MD; Domagoj Coric, MD; Thomas A. Dimmig, MD; David B. Musante, MD * Cervical Disc Arthroplasty (M6 cervical disc prosthesis)

11:10-11:12 am Presentation #84 P

Can C3 Laminectomy reduce Interlaminar Bony Fusion and Preserve Cervical Range of Motion after Cervical Laminoplasty? Dong-Ho Lee, MD, PhD; Jung-Ki Ha, MD; Jae Hwan Cho, MD; Choon Sung Lee, MD, PhD; Chang Ju Hwang, MD; Sunghun Choi, MD; Chul Gie Hong, MD; Youn-Suk Joo, MD

11:13-11:15 am Presentation #85 P

Is it “In” or “Out”? The Optimal Fluoroscopic Views for Intraoperative Determination of Proper Lateral Mass Screw Placement Sangbum Kim, MD, PhD; John M. Rhee, MD; Kun Young Park, MD; Chulmin Kim, PhD

11:16-11:18 am Presentation #86 P

An Approach to Primary Tumors of the Upper Cervical Spine with Total Spondylectomy using a Combined Approach: Our Experience with 19 Cases Feng Wei, MD; Zhongjun Liu, MD, PhD; Xiaoguang Liu, MD, PhD; Liang Jiang; Genting Dang; Peter G. Passias, MD; Miao Yu; Fengliang Wu; Lei Dang

11:19-11:24 am Discussion 11:25-11:48 am Quality: 11:25-11:27 am Presentation #87 P

Collar Fixation is not Mandatory after Cervical Laminoplasty – A Randomized Controlled Study Tetsuro Hida, MD; Yoshito Sakai, PhD; Kenyu Ito; Shiro Imagama, MD

11:28-11:30 am Presentation #88 P

Missing Data May Invalidate Spine Surgery Database Studies Bryce A. Basques, MD; Andre M. Samuel, BBA; Matthew L. Webb, AB; Adam M. Lukasiewicz, MSc; Daniel D. Bohl, MD, MPH; Junyoung Ahn, BS; Kern Singh, MD; Jonathan N. Grauer, MD

11:31-11:33 am Presentation #89 P

Iatrogenic Instability at the Supra-Adjacent Level of Posterior Cervical Instrumentation Constructs for Cervical Laminectomies: A Biomechanical Analysis Sina Pourtaheri, MD; Andrew T. Healy, MD; Daniel Lubelski, MD

11:34-11:36 am Presentation #90 P

Characteristics of Residual Symptoms following Laminoplasty in Diabetic Patients with Cervical Spondylotic Myelopathy: A Prospective Cohort Study in 505 Patients with Cervical Spondylotic Myelopathy Masaaki Machino, MD; Yasutsugu Yukawa, MD, PhD; Shiro Imagama, MD, PhD

11:37-11:39 am Presentation #91 P

Number of Operative Levels Minimally Impacts Risk for Adverse Events following an Anterior Cervical Decompression and Fusion Daniel D. Bohl, MD, MPH; Junyoung Ahn, BS; Dustin H. Massel, BS; Benjamin C. Mayo, BA; Bryce A. Basques, MD; Nathaniel T. Ondeck, BS; Jonathan N. Grauer, MD; Kern Singh, MD

11:40-11:42 am Presentation #92 P

Most 30-day Readmissions after Anterior Cervical Discectomy and Fusion are not due to Surgical Site-related Issues: An Analysis of 10,006 Patients Andre M. Samuel, BBA; Jason O. Toy, MD; Michael C. Fu, MD; Adam M. Lukasiewicz, MSc; Matthew L. Webb, AB; Daniel D. Bohl, MD, MPH; Bryce A. Basques, BS; Todd J. Albert, MD; Jonathan N. Grauer, MD

11:43-11:48 am Discussion 11:49 am-12:12 pm Cervical Myelopathy: 11:49-11:51 am Presentation #93 P

The Efficacy and Safety of Additional Posterior Foraminotomy Performed with Laminoplasty for Cervical Spondylotic Myeloradiculopathy Jung-Ki Ha, MD; Jae Hwan Cho, MD; Choon Sung Lee, MD, PhD; Chang Ju Hwang, MD; Sunghun Choi, MD; Chul Gie Hong, MD; Youn-Suk Joo, MD; Dong-Ho Lee, MD, PhD

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11:52-11:54 am Presentation #94 P

Quality of Life and Functional Outcomes after Surgical Decompression in Patients with Cervical Ossification of the Posterior Longitudinal Ligament: Results from the Prospective, Multicenter AOSpine International Study on 479 Patients Hiroaki Nakashima, MD; Lindsay Tetreault, HBSc; Narihito Nagoshi, MD, PhD; Aria Nouri, MD; Michael G. Fehlings, MD, PhD

11:55-11:57 am Presentation #95 P

The Modified Japanese Orthopaedic Association Scale: Establishing Criteria for Mild, Moderate and Severe Disease in Patients with Degenerative Cervical Myelopathy Lindsay Tetreault, HBSc; Aria Nouri, MD; Anoushka Singh, PhD; Ronald HMA Bartels, MD, PhD; Branko Kopjar, MD; Paul M. Arnold, MD; Michael G. Fehlings, MD, PhD

11:58 am-12:00 pm Presentation #96 P

What Happens to the Disc Bulge after Posterior Laminectomy and Fusion in Patients with Cervical Myelopathy? Saankritya Ayan, MD; Jonathan Morris, MD; Manal Abouelrigal, MD; Woojin Cho, MD, PhD; Alok D. Sharan, MD

12:01-12:03 pm Presentation #97 P

Anterior Decompression with Fusion vs. Posterior Decompression with Fusion for Massive Cervical Ossification of Posterior Longitudinal Ligament with 50% Canal Occupying Ratio or More: Retrospective Multi-Center Study Toshitaka Yoshii, MD, PhD; Takashi Hirai, MD, PhD; Satoshi Sumiya, MD; Tsuyoshi Kato, MD, PhD; Shigenori Kawabata, MD, PhD; Atsushi Okawa, MD, PhD; Kenichi Shinomiya, MD, PhD

12:04-12:06 pm Presentation #98 P

Is it Necessary to Extend a Multilevel Posterior Cervical Decompression and Fusion to the Upper Thoracic Spine? Gregory D. Schroeder, MD; Christopher K. Kepler, MD, MBA; Mark F. Kurd, MD; Loren B. Mead, BS; Kristen Nicholson, PhD; Christie E. Stawicki, BS; Priyanka Kumar, BS; Paul W. Millhouse, MD; Kristen E. Radcliff, MD; Jeffery A. Rihn, MD; D. Greg Anderson, MD; Alan S. Hilibrand, MD; Alexander R. Vaccaro, III, MD, PhD

12:07-12:12 pm Discussion 12:13–12:17 pm Closing Remarks - Robert F. Heary, MD 12:17 pm Adjourn

Online room reservations available at the Manchester Grand Hyatt in San Diego, CA.

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Poster Catalog

E-posters listed by category

Advanced Techniques E-poster #1 Efficacy of Posterior Segmental Decompression Surgery for Pincer Mechanism in Cervical

Spondylotic Myelopathy - A Retrospective Case–Control Study using Propensity Score Matching Akihito Minamide, MD, PhD; Munehito Yoshida, MD, PhD; Hiroshi Yamada, MD, PhD; Hiroshi Hashizume, MD, PhD; Yukihiro Nakagawa, MD, PhD; Hiroshi Iwasaki, MD, PhD; Shunji Tsutsui, MD, PhD; Hiroyuki Oka, MD, PhD

Anterior Cervical Surgery E-poster #2 Efficacy of a Short Plate with an Oblique Screw Trajectory for Anterior Cervical Plating: A

Comparative Study with a Two-Year Minimum Follow-Up. Jong-Hwa Park, MD; Seung-Jae Hyun, MD, PhD; Chang-Hyun Lee, MD; Ki-Jeong Kim, MD, PhD; Jin S. Yeom, MD, PhD

E-poster #3 Prolonged Weakness affects Recovery of Motor Function Following Anterior Cervical

Discectomy and Fusion Ronald Huang, MD; David Beck, MD; Andrew G. Park, MD; Alan S. Hilibrand, MD

E-poster #4 Factors Associated with Morbidity and Mortality in Adults Undergoing Cervical Corpectomy.

Dante M. Leven, DO, PT; Branko Skovrlj, MD; Parth Kothari, BS; Jeremy Steinberger, MD; Javier Z. Guzman Tejero, BS, MD; Nathaniel J. Lee, BS; John I. Shin, MD; John M. Caridi, MD; Samuel K. Cho, MD

E-poster #5 Clinical Outcomes following Anterior Cervical Hybrid Surgery using Total Disc Replacement

Combined with Anterior Cervical Fusion at the Adjacent Segment Roger W. Rogers, DO; Scott L. Blumenthal, MD; Richard D. Guyer, MD; Jack E. Zigler, MD; Donna D. Ohnmeiss, Dr.Med. * ProDisc-C, DePuy Synthes Spine; approved for single-level TDR, but not hybrid

Basic Science E-poster #6 Safety Assessment of NSCS Induced from Human PBMC-Derived IPS Cells for Transplantation

Therapy for Spinal Cord Injury Keiko Sugai, MD; Tomoko Shofuda; Ryuji Fukuzawa; Hayato Fukusumi; Miho Isoda; Shigeki Ohta; Jun Kohyama; Akio Iwanami, MD, PhD; Morio Matsumoto, MD, PhD; Yonehiro Kanemura; Hideyuki Okano; Masaya Nakamura, MD

E-poster #7 Programmed Freeze/Thaw Method Dramatically Improved Cell Viability of IPS Cell-Derived

Neural Stem Cells for Clinical Application in Spinal Cord Injury Yuichiro Nishiyama; Akio Iwanami, MD, PhD; Jun Kohyama; Go Itakura, ATC, BA, BOC, BOCO, BOCP; Yoshiomi Kobayashi, MD, PhD; Soraya Nishimura, MD, PhD; Hiroki Iwai, MD, PhD; Morio Matsumoto, MD, PhD; Hideyuki Okano; Masaya Nakamura, MD

E-poster #8 Cervical Spinal Cord Injury Modifies Distal Lumbar Locomotor Central Pattern Generator (CPG)

Spyridon K. Karadimas, MD, PhD; Kajana Satkunendrarajah, PhD; Mohamad Khazaei, PhD; Simon Gosgnach, PhD; Michael G. Fehlings, MD, PhD

Biomechanics E-poster #9 An In Vitro Evaluation of Sagittal Alignment in the Cervical Spine after Insertion of

Supraphysiologic Lordotic Implants Donald J. Blaskiewicz, MD; Patrick Han, MD; Jeffrey E. Harris, MS; Alexander W. Turner, PhD; Gregory M. Mundis, MD * NuVasive CoRoent Small Interbody system device only cleared for use at one level with anterior cervical plating.

E-poster #10 The Location of Instant Center of Rotation in the Cervical Spine During in Vivo Dynamic

Flexion-Extension Kwang Sup Song, MD; Seong Hwan Kim, MD; Jae Jun Yang, MD; Seung Bum Koo, PhD

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Cervical Arthroplasty E-poster #11 Arthroplasty and ACDF Compared to ACDF Alone for Two- and Three-Level Cervical Disc

Disease Jin Young Kim, MD; K. Daniel Riew, MD

Cervical Fusion E-poster #12 Intraoperative Correction of the O-C2 Angle Can Prevent Dysphagia and/or Dyspnea after

Occipitocervical Fusion Surgery Keita Nakayama, MD; Tetsuya Abe, MD, PhD; Kengo Fujii, MD; Kosei Miura, MD; Masaki Tatsumura, MD, PhD; Masashi Yamazaki, MD

E-poster #13 Does Cervical Sagittal Alignment Correlate with Outcomes following Anterior Cervical

Surgery? John A. Sielatycki, MD; Sheyan Armaghani, MD; Arnold Silverberg, BS; Matthew J. McGirt, MD; Clinton J. Devin, MD; Kevin R. O’Neill, MD, MS

E-poster #14 Outcome of Correction Surgery using Pedicle Screw for Cervical Kyphosis Exclusive of

Ankylosing Spondylitis Hiroshi Miyamoto, MD; Terumasa Ikeda, MD; Kazuki Hashimoto, MD; Masao Akagi, MD

E-poster #15 Cervical Spine Fusion: 16-Year Trends in Epidemiology, Indications, and Bone Morphogenetic

Protein Utilization by Surgical Approach Lukas P. Lampe, MD; Alexander P. Hughes, MD; Peter Derman, MD, MBA; Janina Kueper; Ting Jung Pan, MPH; Federico P. Girardi, MD; Todd J. Albert, MD; Stephen Lyman, PhD

E-poster #16 Preoperative Nomograms Predicting Patient-Specific Cervical Spine Surgery Clinical and

Quality of Life Outcomes Daniel Lubelski, MD; Vincent Alentado, BS; Michael Shriver, BS; Amy Nowacki, PhD; Kalil G. Abdullah, MD; Michael P. Steinmetz, MD; Edward C. Benzel, MD; Thomas E. Mroz, MD

E-poster #17 Comparison of Long Term (5-Yr) Reoperation Rates and Outcomes of Long Fusions to the

Cervico-Thoracic Junction: Multi-Level ACDF with BMP-2 Vs. Posterior Fusions Nicole Record, DO; Michael Faloon, MD, MS; Ki Soo Hwang, MD; Kumar G. Sinha, MD; Kimona Issa, MD; Conor Dunn, MS; Arash Emami, MD * Bone Morphogenic Protein - 2 has a black box warning for use in the cervical spine.

Complications E-poster #18 Risk Factors and Functional Outcomes of Re-Intubation after Anterior Cervical Spine Surgery:

Results from AOSpine North America Multicenter Study on 8,887 Patients Narihito Nagoshi, MD; Michael G. Fehlings, MD, PhD; Hiroaki Nakashima, MD; Lindsay Tetreault, HBSc; K. Daniel Riew, MD; Zachary A. Smith, MD; Wellington K. Hsu, MD; Chadi Tannoury, MD; Tony Tannoury, MD; Vincent C. Traynelis, MD; Paul M. Arnold, MD; Thomas E. Mroz, MD; Anthony De Giacomo, MD; Bruce C. Jobse, MS; Eric M. Massicotte, MD

E-poster #19 The Incidence of an Epidural Hematoma following Cervical Spine Surgery

Gregory D. Schroeder, MD; Alan S. Hilibrand, MD; Paul M. Arnold, MD; David E. Fish, MD, MPH; Jeffrey C. Wang, MD; Zachary A. Smith, MD; Wellington K. Hsu, MD; Ziya L. Gokaslan, MD; Robert E. Isaacs, MD; Adam Kanter, MD; Thomas E. Mroz, MD; Ahmad Nassr, MD; Rick C. Sasso, MD; Michael G. Fehlings, MD, PhD; Zorica Buser, PhD; Mohamad Bydon, MD; Elizabeth Lord, MD; Emily C. Nguyen, MD; K. Daniel Riew, MD

E-poster #20 A Multi-Center Study of the Presentation, Treatment, and Outcomes of Cervical Dural Tears

Kevin R. O'Neil, MD; Michael G. Fehlings, MD, PhD; Thomas E. Mroz, MD; Zachary A. Smith, MD; Wellington K. Hsu, MD; Adam Kanter, MD; Michael P. Steinmetz; MD; Paul M. Arnold, MD; Praveen V. Mummaneni, MD; Dean Chou, MD; Ahmad Nassr, MD; Sheeraz A. Qureshi, MD, MBA; Samuel K. Cho, MD; Evan O. Baird, MD; Justin S. Smith, MD, PhD; Chadi Tannoury, MD, Tony Tannoury, MD, Ziya L. Gokaslan, MD; Robert A. Hart, MD; Robert E. Isaacs, MD; Rick C. Sasso, MD; David B. Bumpass, MD; Mohamad Bydon, MD; Mark Corriveau, MD; Anthony De Giacomo, MD; Adeeb Derakhshan, BS; Bruce C. Jobse, MS; Daniel Lubelski, MD; Sungho Lee, MD; Eric M. Massicotte, MD; Jonathan Pace, MD; Gabriel Smith, MD; Khoi Than, MD; K. Daniel Riew, MD

E-poster #21 Hospital-Acquired Pneumonia Occurs in 20.5% of Cervical Spinal Cord Injury Patients and is

associated with Poor Inpatient Outcomes: An Analysis of 5,198 Patients in the National Trauma Data Bank Andre M. Samuel, BBA; Pablo J. Diaz-Collado, MD; Michael C. Fu, MD; Adam M. Lukasiewicz, MSc; Matthew L. Webb, AB; Daniel D. Bohl, MPH; Bryce A. Basques, BS; Jonathan N. Grauer, MD

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Deformity E-poster #22 Predictive Model for Cervical Alignment Outcomes following Surgical Correction of Adult

Spinal Deformity Peter G. Passias, MD; Cheongeun Oh, PhD; Cyrus Jalai, BS; Nancy Worley, BS; Renaud Lafage, MS; Justin K. Scheer, BS, Eric O. Klineberg, MD; Robert A. Hart, MD; Han Jo Kim; Justin S. Smith, MD, PhD; Virginie C. Lafage; PhD; Christopher P. Ames, MD; International Spine Study Group

E-poster #23 Extent of Proximal Fusion Correlates with Worse Clinical Outcomes in Cervical to Pelvis

Fusions Han Jo Kim, MD; Sravisht Iyer, MD; Alexander A. Theologis, MD; Todd J. Albert, MD; Lawrence G. Lenke, MD; Vedat Deviren, MD; Venu M. Nemani, MD, PhD; Oheneba Boachie-Adjei, MD; Shane Burch, MD; Jun Mizutani, MD; Eric O. Klineberg, MD; Themistocles S. Protopsaltis, MD; Justin S. Smith, MD, PhD; Justin K. Scheer, BS; Christopher P. Ames, MD

Diagnostics E-poster #24 A Novel Radiographic Indicator of Developmental Cervical Stenosis

Phillip H. Horne MD, PhD; Lukas P. Lampe MD; Joseph T. Nguyen, MPH; Richard J. Herzog MD; Todd J. Albert MD

E-poster #25 A Novel Comprehensive MRI Classification System for Cervical Foraminal Stenosis

Sang-Hun Lee, MD, PhD; So-Young Park, MD; Ki-Tack Kim, MD; Sang-Phil Hwang, MD; Soo-Jin Jang, MD; Jeffrey C. Wang, MD

Economics/Value E-poster #26 The Total Cost to the Healthcare System for the Treatment of Cervical Myelopathy

Gregory D. Schroeder, MD; Mark F. Kurd, MD; Kristen E. Radcliff, MD; Jason W. Savage, MD; Jeffery A. Rihn, MD; D. Greg Anderson, MD; Alan S. Hilibrand, MD; Alexander R. Vaccaro, MD, PhD; Christopher K. Kepler, MD, MBA

Laminoplasty E-poster #27 Sagittal Imbalance Might Be a Risk Factor of Increasing Post Laminoplasty Kyphosis

Yoshitaka Suzuki, MD; Tetsuya Ohara, MD; Taichi Tsuji, MD; Tosiki Saito; Ayato Nohara, MD; Ryoji Tauchi, MD; Noriaki Kawakami, MD

Myelopathy E-poster #28 A 30-Meter Walking Test as a Measure of Cervical Spondylotic Myelopathy Severity: Test

Characteristics and Results from Two Multicenter Cohort Studies Parker E. Bohm, BA, BS; Michael G. Fehlings, MD, PhD; Branko Kopjar, MD, PhD; Paul M. Arnold, MD

E-poster #29 Disability and Impairment of the Upper Limb and How they Define the Patient with

Degenerative Cervical Myelopathy (DCM). Sukhvinder K. Kalsi-Ryan, BScPT, MSc, PhD; Jerri M. Clout, BS; Pouya Rostami, BS; Eric M. Massicotte, MD, Mohammed F. Shamji, MD; Michael G. Fehlings, MD, PhD

New Technologies E-poster #30 Noninvasive Evaluation by Magnetospinography of Electrophysiological Activity in the

Cervical Spine after Peripheral Nerve Stimulation in Humans Satoshi Sumiya, MD; Shigenori Kawabata, PhD; Tsuyoshi Yamada, Toshitaka Yoshii, Tsuyoshi Kato, MD, PhD; Atsushi Okawa

Other E-poster #31 Risk and Cost of Reoperation after Single Level Posterior Cervical Foraminotomy: A Large

Database Study Arash J. Sayari, BS; Alexander Tuchman, MD; Jeremiah R. Cohen, BS; John C. Liu MD; Frank L. Acosta, MD; Mark J. Spoonamore, MD; Thomas C. Chen, MD, PhD; Patrick C. Hsieh, MD, MSc; Zorica Buse, PhD; Jeffrey C. Wang, MD

E-poster #32 Over 10-Year Aggravation of Cervical Spine Instabilities in Rheumatoid Arthritis: A Prospective

Cohort Study of Outpatients Hiroaki Hirata, MD, PhD; Takashi Yurube, MD, PhD; Masatoshi Sumi, MD, PhD; Yoshiki Terashima, MD

E-poster #33 Operative Treatment in Patients with Suboccipital Spinal Metastasis: Is a Posterior Approach

Alone Enough? Panya Luksanapruksa, MD; Jacob M. Buchowski, MD, MS; David B. Bumpass, MD; Neill M. Wright, MD

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Outcomes E-poster #34 The Effects of Anticoagulation or Antiplatelet Agents in Cervical Spine Surgery Patients

Jong-Hyun Ko, MD; Ju Rang Lee, MD; Kyung-Jin Song, MD E-poster #35 Morbidity and Mortality Associated with Transoral Approaches to the Cervical Spine

Jeremy Steinberger, MD; Dante M. Leven, DO, PT; Branko Skovrlj, MD; Nathan J. Lee, BS; Parth Kothari, BS; Javier Z. Guzman Tejero; John I. Shin, MD; John M. Caridi, MD; Samuel K. Cho, MD

E-poster #36 Preoperative Functional Status as a Predictor of Morbidity and Mortality following Elective

Cervical Spine Surgery Shobhit V. Minhas, MD; Aditya S. Mazmudar, BA; Alpesh A. Patel, MD

E-poster #37 Stability of Clinical Outcome Measures following Anterior Cervical Spine Surgery

Donna D. Ohnmeiss, Dr.Med; Richard D. Guyer, MD; Jack E. Zigler, MD; Scott L. Blumenthal, MD E-poster #38 Does Patient Satisfaction Reflect Quantitative Pain and Function Measurements in Cervical

Spine Surgery? Kristen E. Radcliff, MD; Domagoj Coric, MD; Han Jo Kim, MD; Elizabeth Roensch, BS; Kyle Marshall, BS; Todd J. Albert, MD

E-poster #39 Identifying Predictors of Upper Body Post-Operative Pain and Disability Improvement in

Surgical Cervical Spine Radiculopathic Patients Peter G. Passias, MD; Kristen E. Radcliffe, MD; Robert E. Isaacs, MD; Kristina Bianco, BA; Cyrus M. Jalai, BA; Nancy J. Worley, BA; Paul M. Arnold, MD; Patrick C. Hsieh, MD, MSc; Alexander R. Vaccaro, III, MD; Michael C. Gerling, MD

E-poster #40 Validation of Patient-Reported Outcomes Measurement Information System (PROMIS)

Computer Adaptive Tests (CATS) in Cervical Spine Surgery Alpesh A. Patel, MD; Surabhi Bhatt, BS; Wellington K. Hsu, MD; Jason W. Savage, MD

Spinal Cord Injury E-poster #41 MRI Prognostic Factors for Ambulatory Ability after Spinal Cord Injury Without Bony Injury

(SCIWOBI) Miki Komatsu, MD, PhD; Kota Suda, MD; Satoko Matsumoto, MD; Chikara Ushiku, MD; Katsuhisa Yamada, MD

E-poster #42 Mechanism of Injury vs. AOSpine Classification: Is the Setting/Environment in which the Injury

Occurs or the Morphology of the Spinal Column Injury the Better Predictor of Severity of Spinal Cord Injury? Marcel F. Dvorak, MD; Nader Fallah, PhD; Vanessa K. Noonan; Charles G. Fisher, MD, MPH; Brian K. Kwon, MD, PhD; John Street, MD, PhD; F. Cumhur Öner; Alexander R. Vaccaro, III, MD

Surgical Issues E-poster #43 Incidence of and Risk Factors for Incorrect Level Needle Localization during Anterior Cervical

Discectomy and Fusion Surgery (ACDF) Deepak Reddy, MD; David T. Endriga, MD; Eric M. Kiskaddon, MD; Steven D. Glassman, MD; Kelly R. Bratcher, RN, CCRP; Katlyn E. McGraw, BA; Leah Y. Carreon, MD, MSc

Trauma E-poster #44 ASIA Impairment Scale Predicts the Need for Tracheostomy after Cervical Spinal Cord Injury.

Benjamin R. Childs, BS; Timothy A. Moore, MD; John J. Como, MD, MPH; Heather A. Vallier, MD E-poster #45 Clearing the C-Spine in Obtunded Trauma Patients Based on Admission CT: A Prospective

Randomized Trial Christopher P. O'Boynick, MD; Timothy M. Lonergan, MD; Howard M. Place, MD

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Disclaimer: Some drugs or medical devices demonstrated at this course may not have been cleared by the FDA or have been cleared by the FDA for specific purposes only. The FDA has stated that it is the responsibility of the physician to determine the FDA clearance of each drug or medical device he or she wishes to use in medical practice.

Academy Policy provides that “off label” uses of a drug or medical device may be described in the Academy’s CME activities so long as the “off label” use of the drug or medical device is also specifically disclosed (i.e., it must be disclosed that the FDA has not cleared the drug or device for the described purpose). Any drug or medical device is being used “off label” if the described use is not set forth on the product’s approved label.

Each presentation in which the FDA has not cleared the drug and/or medical device for the use described (i.e., the drug or medical is being discussed for an “off label” use is noted with an (*) in this scheduled. CME Information: This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the American Academy of Orthopaedic Surgeons and Cervical Spine Research Society. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians. The American Academy of Orthopaedic Surgeons (AAOS) designates this live activity for a maximum of 17.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.