CRIC Cancer Research Informatics Core University of Southern California

CRIC Cancer Research Informatics CoreUniversity of Southern California

Presented by, Aarti Vaishnav, MSCRIC Director

Who we are :We are a team of 13 full time programmers and about 10 part time students.

Different Stake Holders

USC Norris Cancer Center USC Cancer Hospital LAC-USC County Hospital CHLA CTSA – USC Preventive Medicine Dept

(Epidemiology and Population Studies)

What we Do : Patient Registry

Red Cap Protocol CRF

Clinical trials Billing

systems

IRB Systems

Membership Data

EMR Systems

Protocol Managemen

t Tools

Population Based

Studies

Publication Managemen

t

Specimen Managemen

t

Cancer Center Website

QA Committee

Shared Resource Support

Document Managemen

t

Grant Data Managemen

t

DSMB Committee

Scientific Committee

(CIC)

CTRP/Clinical

Trials.gov Hospital

Registry DB

What we do not do :

Manage Servers

Provide PC Support

We have moved these tasks to a centralized USC KECK IT Support Team since middle of last year.

CRIC Work Distribution

22%

23%

9%

10%

36%

CCSG (Infras-tructure)

CISO

Admin/Website

Cores/Business Of -fice

Recharge

CISO : Clinical Investigator Support OfficeCISO serves as a centralized unit to

oversee the clinical research infrastructure and assist investigators in their conduct of clinical trials and translational research projects

Staff : 60 + Investigator Initiated Protocols : 49 Total Open protocols : 170

CISO Specific Activities

Support Patient Registry Data collection for all in house

(Investigator Initiated Trials) Summary Reports Protocol Tracking and Management Document Management Interaction with istar (IRB) User support

CISO FORMS- REPORTS

Patient Demographics Form

Patient Registration Form

Off Study Form

Protocol Violation Report

Med Watch form (Serious Adverse Events)

In House Studies (PI initiated)

Protocol Documents

Form Binding Viewer

Record Locking

Role Editor

Integrated Web Browser

CISO Related Committees CIC : Clinical Investigation Committee

DSMC : Data Safety Monitoring Committee

QAC : Quality Assurance Committee

Phase I Committee

All reports used by these committees are generated by CRIC.

CC Administration Manage CC Website

Support all other cores (automated ordering, tracking and management)

Manage CC Member data

Manage Publications data

Manage Grants/Proposal data

Cancer Center Website

Website -Shared Resource Cores

Web Order Form (Cell and Tissue)

Reserve shared Resouce Equipments (Flow Cytometry)

Publication Management ProcessActive CCMember

List(Author Name + Keywords

+ Date Range)

Download from PubMed eUtils Web Service

Review by CC Members

(Email is sent to member for review)

Missing publication are added manually

Auto Assign Program for each publication

based on current membership

Batch Upload to the website

Cancer Center Membership

Publications for each Member

Publication for each Program

Membership Database

BioSketch Management

Grants Information

One Click Summary Reports

Recharge projects: Lab/Specimen Management projects

Prevention studies

Disease Specific cohort projects

Support Consortium databases (ex : NANT)

Other Misc projects.

How do we support all these efforts ?

We use a in-house developed framework called CAFÉ:

Common Application Framework Extensible

CAFÉ uses VB.net and SQL server

We use SQL Reporting Services for all Reports

CAFÉ Key Features Integrated Features

Audit Trail Access TrackingRole based Security Automated Message SystemFully Customizable Remote Login

Record Locking Integrated Reports Dash boardsEasy DeploymentReusability of formsAutomated Data dictionaries

CAFÉ Projects (2004 – 2011)Over a 100 Café Projects have been created over the last 5 years to support various types of Research Activities at USC.

Free Café Licensing.

We are working on making free CAFÉ license available to anyone who wants to use it.

License will be available by May 2011.

Please contact :Aarti VaishnavDirector, Cancer Research Informatics [email protected]

Any Questions ???

For additional Information, please visit:

http://cafe.usc.edu