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Allergy'&'Asthma'Network'NewsMore%information%at%allergyasthmanetwork.org
Meet%the%Allergy%&%Asthma%Network%Team%–Look%for%“About%Us”%&%“Meet%Our%Team”
Distinguishing%the%Difference:%%COVIDF19%vs.%Allergies%vs.%the%Flu%– Infographic in%our%COVIDF19%Information%Center
Webinar – Thursday,%December%10th – 4:00%PM%ETChronic%Rhinosinusitis:%Making%Treatment%Decisions
COVID&19)&)COPD:)Coordinating)Care
Dr.$Purvi ParikhDr.$Vickram Tejwani
Tonya$Winders
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Our$Speakers
Dr.$Vickram TejwaniPulmonary$and$Critical$Care$Fellow$Johns$$Hopkins$Pulmonary$Critical$Care Medicine
Dr.$Purvi ParikhClinical$Assistant$Professor$of$Medicine$NYU$Langone$School$of$Medicine &$Director,$Allergy$and$Asthma$Association,$Murray$Hill
National$Spokesperson,$$$$$$$$$$Allergy$&$Asthma$Network$
Tonya$WindersPresident$&$CEO,$Allergy$&$Asthma$Network
President,$Global$Allergy$&$Airways$Patient$Platform
Outline
! Current*State*of*COVID*– 19
! COPD*Overview*
! COPD*Care*During*COVID919
! Special*Considerations*for*COPD*Patients
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Poll$Question
!We’d%like%to%know%who%is%here%today.!Which%category%best%describes%you?
Current'State'of'COVID019
Tonya&Winders
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US#Data#Report#–CDC#
Cases#in#the#last#7#days
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In#the#News#– Two#Vaccines
Pfizer
Applied#to#FDA#for#emergency#use#authorization#of#
vaccine#– 11/27/20
Documents#online#–Hearing#set#for#December#10th
Moderna
Applied#to#FDA#for#emergency#use#authorization#of#
vaccine#– 11/30/20#
Trial#has#been#same#size#&#scope#as#for#
any#vaccine
What#does#emergency#authorization#mean?
Fastest#way#for#public#health#officials#to#get#
a#vaccine#to#the#public
Dramatically#shortened#drug#development#&#approval#process
Approved(
for(use(in(UK
VACCINE#READY#TO#SHIP#24#HOURS#AFTER#APPROVAL
McKinsey)&)Co.)Article)–
11/23
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In#the#News
! CDC#– COVID/19#likely#to#have#been#in#US#since#mid/December#2019#– earlier#than#originally#thought
! CDC#is#finalizing#recommendation#to#shorten#COVID/19#quarantine#times! 7#– 10#days#with#a#negative#test#to#exit#quarantine
! Coronavirus#spikes#expected#to#be#seen#due#to#holiday#travel! Dr.$Fauci:$
! Expect#even#larger#spikes#during#Christmas#season
! Children#should#be#in#school
In#the#News
! Testing#numbers#could#be#erratic#in#the#next#few#weeks:! Testing#sites#working#on#shortened#holiday#hours
! Many#people#traveling#– tests#required#to#return#home
! Need#to#look#at#the#picture#over#7#days! Dr.#Brix:##“If#you#traveled#over#Thanksgiving,#assume#you#were#exposed#&#became#infected.
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In#The#News
Journal#of#Allergy#and#Clinical#Immunology#–study• Of#the#subjects#positive#for#the#virus,#6.75#percent#had#asthma,#compared#to#9.62#percent#of#those#who#were#negative#for#COVIDJ19,#according#to#the#study#results.
• 3#explanations:• Asthma#is#associated#with#lower#ACE2#receptors#–mechanism#for#virus#to#infect#cells
• People#with#asthma#take#more#precautions• Inhaled#corticosteroids#may#reduce#risk#of#the#virus
COVID&19)Cases)in)US)by)Date)Reported
0
20000
40000
60000
80000
100000
120000
140000
160000
180000
February)28
March)6
March)13
March)20
March)27
April)3
April)10
April)17
April)24
May)1
May)8
May)15
May)22
May)29
June)1
June)8
June)15
June)22
June)29
July)6
July)13
July)20
July)27
August)3
August)10
August)17
August)24
August)31
Septem
ber)7
Septem
ber)14
Septem
ber)21
Sepember)28
October)5
October)12
October)19
October)26
Novemb
er)2
Novemb
er)9
Novemb
er)16
Novemb
er)23
Novemb
er)30
New)Cases)by)Day
Cases
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Poll$Question
! Public'health'guidance'in'my'area'is'requesting/requiring'stricter'social'distancing'&'wearing'of'masks.
COPD%Overview
Dr.$Purvi Parikh
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Chronic(Obstructive(Pulmonary(Disease(
EMPHYSEMA• Tiny(air(sacs(in(the(lungs(where(oxygen(transfers(into(the(bloodstream(are(damaged
• Air(may(also(become(trapped(in(the(lungs(and(hard(to(breathe(out
CHRONIC-BRONCHITIS• Bronchial(tubes(become(irritated(or(swollen
• Excess(mucus(and(coughing(can(last(up(to(three(months
• Bronchial(tubes(may(lose(their(cilia• Cilia(– tiny(hairs(that(move(mucus(so(it(can(be(coughed(out
Chronic(obstructive(pulmonary(disease,(or(COPD,(is(an(umbrella(term(used(to(describe(a(series(of(progressive(lung(diseases(characterized(by(difficulty(breathing.(The(two(primary(COPD(diseases(are:
384$Millionpeople%suffer%from%COPD%in%the%world%
3$Millionpeople%die%each%year%from%%COPD
COPD%is%currently%the%
3rdLeading%cause%
of%death%globally
COPD%is%now%prevalent%in%
low%resource%countries
COPD
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COPD%Annual%Costs
$32.1%Billion%in%2010Project%to%increase%to%%$49%Billion%in%2020
Early&Diagnosis&
Symptoms&include:! Shortness&of&breath! Repetitive&cough! Increased&phlegm&or&mucus&production
! Fatigue! More&frequent&chest&infections! Longer&to&recover&from&a&cold/chest&infection&
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Biggest'Risk'Factors'for'COPD
Smoking• Indoor,&,Outdoor,Pollution
• Occupational,Dusts,&Chemical
Although(30%(of(COPD(patients(never(
smoked!
COPD%Patients
COPD%most%often%occurs%in%people%more%than%40%years%of%age%who%smoke%or%have%done%so%earlier%in%life
• May%have%experienced%long@term%exposure%to%chemicals
COPD%typically%builds%up%over%time,%and%so%the%longer%someone%exposes%themselves%to%potential%lung%damage,%the%more%likely%it%is%that%they%might%develop%COPD• The%lungs%of%people%who%are%younger%may%recover%from%potential%irritants%faster%than%those%of%people%who%are%older
• Lung%damage%may%not%be%enough%to%cause%symptoms,%as%COPD%typically%takes%years%to%produce%noticeable%signs
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Definition(of(ACO
Asthma0COPD(overlap((ACO)(is(characterized(by(persistent(airflow(limitation(with(several(features(usually(associated(with(asthma(and(several(features(usually(associated(with(COPD
Asthma0COPD(overlap(is(identified(in(clinical(practice(by(the(features(that(it(shares(with(both(asthma(and(COPD
This(is(not(a(definition,(but(a(description(for(clinical(use,(as(Asthma0COPD(Overlap(includes(several(different(clinical(phenotypes(and(there(are(likely(to(be(several(different(underlying(mechanisms.
ACO
Asthma COPDACO
Symptoms/of/both/Asthma/&/COPD
Symptoms:
• Labored/breathing• Wheezing• Coughing,/with/or/without/mucus
• Tightness/in/the/chest
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It#Can#Be#a#Bit##Confusing#.#.#.#
Many#patients#with#symptoms#of#chronic#airways#disease#have#features#of#both#asthma#and#COPD#• This#has#been#called#AsthmaBCOPD#Overlap#(ACO)
AsthmaBCOPD#overlap#is#not#a#single#disease#
• Likely#that#a#range#of#different#underlying#mechanisms#and#origins#will#be#identified#
Patients#with#features#of#both#asthma#and#COPD#have#worse#outcomes#than#those#with#asthma#or#COPD#alone• Frequent#exacerbations#B Poor#quality#of#life#B More#rapid#decline#in#lung#function#B Higher#mortality#B Greater#health#care#utilization
How$does$COPD$affect$people’s$lives?
• Difficulty$with$physical$activities$like$walking$&$climbing$stairs• May$not$be$able$to$work• Hard$to$engage$in$social$activities$like$eating$out,$going$to$places$of$worship,$or$getting$together$with$friends$or$neighbors• Increased$confusion,$memory$loss,$depression,$or$other$mental$or$emotional$conditions• More$emergency$room$visits$or$overnight$hospital$stays
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Oxygen'Use
! People'with'severe'COPD'who'have'low'levels'of'oxygen'in'their'blood'may'be'treated'with'supplemental'oxygen'at'home
! Therapy'involves'breathing'in'oxygen'through'a'nasal'tube'or'mask'from'a'metal'tank'cylinder'or'oxygen'concentrator
! COPD'patients'should'check'with'their'oxygen'provider'to'be'sure'they'have'an'adequate'supply'during'COVIDB19
https://www.nih.gov/newsBevents/nihBresearchBmatters/longBtermBoxygenBcopd
Pulmonary*Rehabilitation
A*formal*program*to*help*build*fitness*and*help*patient*breathe
Exercise
Breathing*techniques
Nutrition
Relaxation
Emotional*&*group*support
Learning*about*medications
Strategies*for*living*better*with*COPD
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Pulmonary*Rehabilitation
Usually*an*outpatient*program
Might*work*with*an*interprofessional*team• Respiratory*Therapists• Dietitians• Social*Workers
Pulmonary*Rehabilitation*during*COVID819
! Most*Pulmonary*Rehab*Centers*have*temporarily*suspended*face8to8face*programs
! Virtual*Pulmonary*Rehab*via*telehealth,*phones,*video8conferencing! As*social*distancing*guidance*changes,*small*groups*can*meet! Most*important*issues*are*PATIENT*AND*STAFF*SAFETY,*to*avoid*contracting*and*further*spreading*COVID819*
! General*principles*of*infection*control*should*apply*until*there*is*an*effective*vaccine*that*is*widely*available*and*utilized.*Where*new*case*rates*are*high,*it*is*unlikely*that*center8based*rehabilitation*will*be*appropriate*for*people*with*chronic*respiratory*disease.
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COPD%Care%During%COVID/19
Dr.$Vickram Tejwani
COPD%Patients
! A%large%population%of%patients! COPD%is%progressive%5 it%gets%worse%as%time%goes%on
• Not%at%an%increased%risk%of%GETTING COVID519Good(news:
• Increased%risk%for%SEVERECOVID519Bad(news:
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COPD%&%COVID)19
• People%with%COPD%experience%shortness%of%breath%or%dyspnea
COPD
• People%with%COVID)19%experience%shortness%of%breath%or%dyspnea
COVID)19 • How%can%you%tell%the%difference?!?
???
COPD%&%COVID)19
COPD! Shortness-of-breath! Repetitive-cough! Increased%phlegm%or%mucus%production
! Fatigue
COVID:19! Shortness-of-breath! Repetitive-cough! Fever! Anorexia%(no%appetite)! Myalgias%(muscle%pain)! Gastrointestinal%symptoms
! Nausea! Diarrhea
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COVID&19)&)Comorbid)Conditions
You$are$increased$risk$of$severe$disease$if$you also$have$one$of$the$following:Cancer Liver)diseaseChronic)kidney)disease OverweightCOPD Pulmonary)fibrosisHeart)conditions)(heart)failure,coronary artery)disease,)cardiomyopathies)
Thalassemia)(a)blood)disorder)
Immunocompromised)state)(organ)translplant,)chemotherapy,)and)more)
Type)1)diabetes
Neurologic)conditions)(dementia)
COPD%&%COVID)19
• 98%%of%people%with%COPD%agree%they%want%to%be%as%healthy%as%the%can%be%to%fight%off%COVID>98%
• 83%%of%people%with%COPD%agree%that%COVID%has%been%a%wake)up%call%to%realize%their%disease%puts%them%at%risk.83%
• 54%%of%people%with%COPD%feel%more%depressed%about%having%COPD%and%its%impact%on%their%future.54%
https://us.gsk.com/en)us/behind)the)science/patients)consumers/breaking)barriers)for)better)copd)care/
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COPD%&%COVID)19%Care
! Inhalers! Bronchodilator%therapy%should%be%switched%from%nebulizer%to%an%inhaler%– either%metered)dose%inhaler%or%dry%powder%inhaler
! Should%use%a%spacer! Nebulizers
! Healthcare%workers%in%the%room%should%wear%personal%protective%equipment%(PPE)%appropriate%for%airborne%precautions
! Viral%particles%can%stay%airborne%for%1%– 3%hours
Management%of%patients%with%COPD%during%the%COVID)19%pandemicAmy Attaway, Umur Hatipoğlu
Cleveland%Clinic%Journal%of%Medicine Jul%2020, DOI: 10.3949/ccjm.87a.ccc007
COPD%&%COVID)19%Care
Significant%numbers%of%patients%will%treat%their%illness%at%home
Should%self)isolate%in%a%room
Ideally,%they%should%have%their%own%bathroom
If%nebulizer%is%needed,%it%should%be%used%in%a%room%with%the%doors%closedShould%remain%closed%for%several%hours%afterwards
Frequent%cleaning%&%disinfecting%of%surfaces%in%room
Medication%regimen%should%not%be%changed%without%discussion%with%doctor
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Emergency)COPD)&)COVID119)Care
If)COVID119)worsens,)pneumonia)can)develop
• Lung)inflammation)– fills)airway)sacs)with)fluid)– can)be)life1threatening
Acute)respiratory)distress)syndrome)(ARDS))can)also)develop
• May)need)to)be)placed)on)a)ventilator)to)get)enough)oxygen
If)you)have)COVID119)and)it)becomes)difficult)to)take)a)breath)1 be)prepared)to)call)911
What%Can%COPD%Patients%Do%to%Stay%Healthy?• Stay%at%home• Practice%the%3"W’s• Wash your%hands• Watch your%distance• Wear a%mask
• Avoid%sick%people• Clean%&%disinfect%surfaces• Reduce%your%stress,%enjoy%your%hobbies• Exercise,%eat%a%healthy%diet• Stay%connected%by%“virtual%means”
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Special(Considerations(for(COPD(Patients
Tonya&Winders
The$COPD$Charter
• Outlines$6$principles$of$quality$care$that$people$with$COPD$should$expect$to$receive,$wherever$they$live.
Global$Policy$Document
• To$mobilize$governments,$healthcare$providers,$policymakers,$lung$health$industry$partners$and$caregivers$to$address$the$unmet$need$and$burden$of$COPD
• Ultimately$working$together$to$deliver$meaningful$improvements$in$care,$now$and$in$the$future.$
• Aims$to$offer$a$consensus$on$global$standards$of$COPD$care.
Purpose$of$the$Charter
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Why$Do$We$Need$a$COPD$
Charter?
• Global$strategies$&$guidelines$exist,$but$there$are$vast$inconsistencies$in$the$way$people$with$COPD$are$managed,$having$a$devastating$impact$on$people$living$with$the$disease• COPD$does$not$receive$the$same$level$of$recognition$and$prioritization$globally• Healthcare$systems$and$providers$are$not$adequately$equipped$to$deliver$optimal$COPD$care$and$policy$reform$is$urgently$needed$to$drive$a$reduction$in$both$mortality$and$exacerbation$rates
Principles*of*Quality*Care*in*COPD
1• I*deserve*timely*access*for*the*diagnosis*and*assessment*of*my*COPD
2• I*deserve*to*understand*what*having*COPD*means*for*me*and*how*the*disease*may*progress
3• I*deserve*access*to*the*best*available*evidence>based,*personalized*treatment,*to*ensure*I*can*live*as*well*and*as*long*as*possible
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Principles*of*Quality*Care*in*COPD
4• I*deserve*an*urgent*review*of*my*current*management*plan*if*I*experience*an*‘exacerbation’,*to*prevent*further*exacerbations*and*disease*progression
5• I*deserve*access*to*specialist*care*when*needed*(whether*provided*in*hospital*or*in*the*community)*to*manage*my*COPD,*irrespective*of*where*I*live
6• I*deserve*to*live*with*COPD*freely*while*maximizing*quality*of*life*without*stigma*or*guilt
How$will$the$COPD$Charter$support$quality$care?
Drive$awareness$of$the$current$unmet$need$and$burden$in$COPD$and$highlight$to$governments,$healthcare$providers,$policymakers,$lung$health$industry$partners$and$caregivers$the$quality$care$that$people$with$COPD$should$expect$to$receive,$wherever$they$liveBy$sharing$the$COPD$Patient$Charter,$we$intend$to$engage$key$stakeholders$to$adopt$the$Patient$Charter$principles.$This$is$vital$if$we$are$to$address$the$unmet$need$and$burden$in$COPD$and$ultimately$work$together$to$deliver$meaningful$improvements$in$care,$both$now$and$in$the$future.
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COPD%Patients
COPD%Patients%have%the%right%to%quality%guidelines6based%healthcare%delivered%in%a%timely%and%collaborative%way.
Poll$Question
!In#my#geographical#area,#pulmonary#rehab#is#being#managed#on#telehealth.
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Questions?
Please&record&your&questions&in&the&Question&box&on&your&webinar&control&panel
We&will&address&as&many&questions&as&we&can
COVID&19)Vaccine)– Treatment,)Trust)&)Health)Inequities
Join%us%on%Tuesday,%December%15th for%the%18thwebinar%in%our%COVID>19%Webinar%Series%>
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COVID&19)&)COPD:)Coordinating)Care
Thank&you&for&listening!Get&guidelines5based&information&at&
allergyasthmanetwork.org