Course Guide 33047 Genetics COURSE DATA Data Subject Code 33047 Name Genetics Cycle Grade ECTS Credits 10.0 Academic year 2019 - 2020 Study (s) Degree Center Acad. year Period 1100 - Graduado/a en Biología Faculty of Biological Sciences 2 Annual Subject-matter Degree Subject-matter Character 1100 - Graduado/a en Biología 7 - Molecular and genetic basis of living beings Obligatory Coordination Name Department CUEVAS TORRIJOS, JOSE MANUEL 194 - Genetics PASCUAL CALAFORRA, LUIS FCO. 194 - Genetics SILVA MORENO, FRANCISCO J. 194 - Genetics SUMMARY The course of Genetics is taught in second course curriculum Degree in Biology from the University of Valencia. It’s part of the Molecular and genetic material of living beings, which is composed of three subjects. Two are 10 ECTS each, Biochemistry and Genetics, while the third, Molecular Biology Methods is 6 ECTS. The course of Genetics is theoretical and practical and will be held throughout both semesters that make up the academic year. The delivery of the contents of molecular genetics / molecular biology has been coordinated with the other two subjects with special attention to developing a coordinated program of activities and contents in order to avoid overlaps. The objectives related to the acquisition of practical skills will be especially shared and supplemented with the subject of Molecular Biology Methods as this course aims to integrate different disciplinary-cellular molecular techniques, several of which have a clear connection to our area knowledge. In addition, continuing the process of coordination of content between subjects, some aspects of evolutionary genetics are included in the subjects Tree of Life (6 ECTS), first course, and Evolutionary Processes and Mechanisms (4.5 ECTS) given during the first semester of the second course, while not the same, therefore, between the contents of the subject of Genetics. 33047 Genetics 1
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Course Guide33047 Genetics
COURSE DATA
Data SubjectCode 33047Name GeneticsCycle GradeECTS Credits 10.0Academic year 2019 - 2020
Study (s)Degree Center Acad.
yearPeriod
1100 - Graduado/a en Biología Faculty of Biological Sciences 2 Annual
Subject-matterDegree Subject-matter Character1100 - Graduado/a en Biología 7 - Molecular and genetic basis of living
beingsObligatory
CoordinationName DepartmentCUEVAS TORRIJOS, JOSE MANUEL 194 - GeneticsPASCUAL CALAFORRA, LUIS FCO. 194 - GeneticsSILVA MORENO, FRANCISCO J. 194 - Genetics
SUMMARYThe course of Genetics is taught in second course curriculum Degree in Biology from the University of
Valencia. It’s part of the Molecular and genetic material of living beings, which is composed of three
subjects. Two are 10 ECTS each, Biochemistry and Genetics, while the third, Molecular Biology Methods
is 6 ECTS. The course of Genetics is theoretical and practical and will be held throughout both
semesters that make up the academic year.
The delivery of the contents of molecular genetics / molecular biology has been coordinated with the
other two subjects with special attention to developing a coordinated program of activities and contents
in order to avoid overlaps. The objectives related to the acquisition of practical skills will be especially
shared and supplemented with the subject of Molecular Biology Methods as this course aims to integrate
different disciplinary-cellular molecular techniques, several of which have a clear connection to our area
knowledge.
In addition, continuing the process of coordination of content between subjects, some aspects of
evolutionary genetics are included in the subjects Tree of Life (6 ECTS), first course, and Evolutionary
Processes and Mechanisms (4.5 ECTS) given during the first semester of the second course, while not
the same, therefore, between the contents of the subject of Genetics.
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The general objectives of the course are to provide the student genetics on the one hand, basic
knowledge concerning the study of biological variability and the mechanisms that regulate their heritage,
and the structure and function of genes and genomes, and other tools conceptual and methodological
enable it to carry out any type of genetic analysis in their professional work.
PREVIOUS KNOWLEDGE
Relationship to other subjects of the same degreeThere are no specified enrollment restrictions with other subjects of the curriculum.
Other requirements
OUTCOMES
1100 - Graduado/a en Biología - Skills in analysis and synthesis. - Capacidad de resolución de problemas. - Capacidad de razonamiento crítico. - Capacidad de aprendizaje autónomo. - Capacidad de comunicación oral y escrita. - Capacidad de manejar el inglés como vehículo de expresión científica. - Capacidad de utilizar las nuevas tecnologías de información y comunicación. - Comprender el método científico. - Capacidad de trabajar en equipo. - Saber hacer análisis de datos científicos. - Capacidad de búsqueda de información y análisis crítico de textos científicos. - Conocer los mecanismos de la herencia biológica. - Conocer los mecanismos de replicación, transcripción, traducción y modificación del material
genético. - Conocer las bases biológicas del desarrollo. - Conocer las metodologías de análisis global estructural y funcional de genomas y procesos celulares. - Conocer la estructura y función de las biomoléculas. - Conocer los conceptos básicos y las aplicaciones de la tecnología del DNA recombinante y de la
Ingeniería Genética. - Capacidad para trabajar correctamente en los laboratorios de Bioquímica, Genética y Biología
Molecular, incluyendo seguridad, manipulación, eliminación de residuos y registro anotado deactividades.
- Capacidad para utilizar la instrumentación básica en los laboratorios de Bioquímica, Genética,Biología Molecular y Celular.
- Tener una visión integrada de las técnicas y métodos utilizados por la Bioquímica, Genética yBiología Molecular.
- Capacidad para diseñar experimentos y aproximaciones multidisciplinares para la resolución deproblemas concretos.
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- Capacidad para presentar, discutir y extraer conclusiones de los resultados de los experimentoscientíficos.
LEARNING OUTCOMES1. Resolving issues and problems
2. Practical activities in the laboratory and analytical results.
3. Work experience in the computer lab and interpret the results.
4. Conducting group work and written and oral presentation with audiovisual support.
5. Design experiments to solve specific problems.
6. Perform genetic analysis.
7. Manipulating the genetic material.
8. Analyzing and comparing nucleic acid sequences and proteins.
9. Integrating molecular and genetic aspects of cellular organization and function
DESCRIPTION OF CONTENTS
1. Introduction to GeneticsDefinition and objectives of genetics.Basics: genotype, phenotype and standard reaction.Phenocopies.PleiotropyGenetic analysis.Mutation: definition and types.Relations between alleles.
2. Patterns of inheritance.Cytological basis of inheritance, mitosis and meiosis.Genetic consequences of meiosis.Gregor Mendel: the reasons for success.Monohybrid Crossing: Law of segregation.The testcross.Dihybrid analysis: Law of the transmission.Genetic notation.The use of diagrams branched and crosstabs.The chi-square test.Analysis of polyhybridism.Study and calculation of probabilities in genealogies
3. Extensions of Mendelian analysis
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The AB0 blood group system, an example of multiple allelism.How to establish dominance between alleles series.Lethality.Relationships between genes: interaction and epistasis.Penetration and expressiveness.Influence of the environment on gene expression.
4. Gene function and complementationA. Garrod and inborn errors of metabolism.G. Beadle, E. Tatum and the beginning of biochemical genetics.The genetic dissection of a biochemical pathway.Sickle cell anemia: Each gene encodes a polypeptide.Gene complementation.The flow of hereditary information.
5. Genetics of quantitative traits.The multiple factors.Standard reaction and phenotypic distribution.Dismembering the phenotypic variance.When is worth doing selection?Heritability.How to calculate the heritability of a character.
6. Population geneticsThe genetic pool.Frequency of genes and genotypes.The Hardy-Weinberg law.Extensions of the Hardy-Weinberg law.How to tell if a stock is in equilibrium.Using the Hardy-Weinberg law to estimate gene frequencies.
7. Chromosomes, sex and heredityEstablishment of the chromosome theory of heredity.Linked inheritance sex chromosomes.Dosage compensation.Sex determination systems.Role of X and Y chromosomes in Drosophila and humans.Influence of sex on inheritance and gene expression.Influence of environment on gene expression.
8. Genetic linkage
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The transfer of linked genes.Meiotic recombination.Detection of linkage.Recombination, genetic distance and linkage map.Mitotic recombination.Intragenic recombination.
9. Genetic mapping in eukaryotesThe map of three points.How to proceed when we do not know the order of genes.Genetic distance and physical distance.The phenomenon of interference.Double crossovers and map functions.Distance from the dihybrid.Linkage analysis in pedigrees: lod score.Segregation and recombination in haploids: tetrad analysis.
10. Transferring, recombination and maps of the hereditary material in bacteria and virusesThe transformation and cotransformation maps.The bacterial conjugation.Characteristics of the factor F.Interrupted mating maps.Taking advantage of the phage, transduction.Cotransducción maps.Recombination in viruses.Intragenic recombination.
11. The nature of the hereditary material: Nucleic acids and InheritanceFeatures to be met by the hereditary material.The transforming principle of F. Griffith.Establishing the nature of the transforming principle.RNA is the hereditary material of some viruses.Interactions between DNA and proteins.
12. The chromosome: inheritance vehicleChromatin: composition and organization.From the nucleosome to the metaphasic chromosome.Centromere, telomere and nucleolar organizer.Morphology and chromosome number.Karyotype.Staining of chromosomes.The hybridization "in situ" as a technique for chromosome identification.Euchromatin, heterochromatin and position effect.
13. Chromosomal mutations
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A classification of chromosomal mutations.Structural changes.Duplications and deletions affect the number of genes in the chromosomes.Inversions and translocations change the physical location of genes.Numerical changes.Chromosomal fusion and fission: Robertsonian translocations.Aneuploidy a partial change in chromosome sets.Polyploids: a variation of the euploidía.
14. Physical mapsDeletion maps.The use of balancer chromosomes in genetic analysis.Using deletions to map mutations.Maps by somatic cell hybridization.Irradiated hybrid maps.Maps by hybridization "in situ".
15. Gene expression and genetic code.Gene expression.Genes coding and noncoding RNA genes.Characteristics of the genetic code.Deciphering the genetic code.The anticodon and the wobble hypothesis.Universality of the genetic code.Effect of codon usage.
16. Molecular basis of gene mutationHow the mutation affects genetic material.Basic characteristics of the mutational phenomenon.The molecular basis of spontaneous mutation.Induced mutations, mutagenic chemicals and ionizing radiation
17. DNA repair and recombinationA look at the repair systems.The molecular mechanism of recombination.The process of homologous recombination.The breakage and reunion model proposed by Holliday.Hybrid DNA, mismatch repair and gene conversion.
18. Molecular analysis of genetic variationDNA polymorphism concept.DNA polymorphism analysis of minisatellite probes.Analysis of DNA polymorphisms using PCR.The interpretation of the biological test: the fallacies of the public prosecution and defense.Bayesian analysis.Pharmacogenetics: an example of genetic individuality
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19. Control of gene expression in prokaryotes.Regulated and constitutive genes.An overview of regulation in prokaryotes.Global circuits of control of gene expression.Inducible systems: gene regulation of lactose metabolism in E. coli.Lac operon model of Jacob and Monod.Catabolite repression: control by positive induction in the lac operon.Repressible and negative control: the trp operon.Regulation by attenuation of the trp operon.
20. Control of gene expression in eukaryotes.An overview of the levels of gene regulation in eukaryotes.How to activate a eukaryotic gene.The role of enhancers and activators of transcription factors.A model for activation of transcription.Gene regulation in the maturation of mRNA.Coordinated control of transcription: the role of hormones.Other levels of regulation.
21. Developmental geneticsGenetic basis of differentiation.Binary cell fate decisions: sex determination.Specification of the anteroposterior axis in Drosophila.Floral development in A. thaliana.Development and evolution processes.
22. Cancer geneticsCancer as a genetic disease.Cell cycle control.Programmed cell death.Genetic basis of cancer: oncogenes and tumor suppressor genes.Hereditary predisposition to cancer.
23. EpigeneticsEpigenetic alterations of the genomeEpigenetics and imprintingEpigenetics and CancerEpigenetics and behaviorEpigenetics and the environment
24. Introduction to Genomics: transposable elements
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Genomics: Definition and types.C value paradox: genome size.The complexity of eukaryotic DNA.Genomes of prokaryotes.Eukaryotic nuclear genomes: genetics.Organelle genomes of eukaryotesComparative genomics.The dynamic genome: transposable elements.Mechanisms of transposition.Mutagenic effects of transposition.Transposable elements of bacteria.Transposable elements of eukaryotes.
25. Evolution of genomesAcquisition of new genes.Genomics and gene duplication.Duplication of domains and domain shuffling.Horizontal gene transfer.Introgression and Allopolyploidy.Non-coding DNA and genome evolution.Effect of transposable elements in the evolution of genomes.
WORKLOAD
ACTIVITY Hours % To be attendedTheory classes 57,00 100Classroom practices 22,00 100Laboratory practices 10,00 100Computer classroom practice 6,00 100Tutorials 5,00 100Development of group work 10,00 0Development of individual work 10,00 0Study and independent work 50,00 0Preparation of evaluation activities 35,00 0Preparing lectures 25,00 0Preparation of practical classes and problem 20,00 0
TOTAL 250,00
TEACHING METHODOLOGYFor the development of theoretical activities expository method and lecture are used, but by involving
students with questions about cases or problems.
For practical work we use the methodology of solving exercises and problems (exercises, testing and
implementation of knowledge). It strongly encourages teamwork, as both activities in the laboratory,
problems, such as computer room are conducted in groups.
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The activities of the course are complete and complement the transverse activity "Interdisciplinary
Seminar" directly focused on the job competencies.Alternatively to this activity any other transversal
activity backed by CAT can be carried out as part of a project of educational innovation
The development of the course is divided into:
Class work:
A. Two or three weekly sessions of theory classes for one hour. In these sessions is present and discuss
the basics of the subject with a focus on highlighting the practical aspects of the same. It is highly
recommended prior reading of the issues. A total of 57 required one-hour sessions to cover this facet of
teaching.
B. A weekly practical session of two hours. Here are five laboratory sessions (10 hours), eleven problem
sessions (22 hours) and three practical sessions in computer lab (bioinformatics) (6 hours).
C. The availability of five sessions of one hour of tutoring group. These sessions are listed in the agenda
distributed throughout the teaching period and allow us to deepen, so eminently practical and
participatory on the conceptual aspects of the subject by working in groups.
Independent work:
D. Interdisciplinary work: completion and presentation of a seminar. In this activity participate all
subjects in the second degree course in Biology (Cell and Tissue Biology, Developmental Biology,
Biochemistry, Botany, Genetics, Methods in Molecular Biology, Evolutionary Processes and Mechanisms
and Zoology). The activity is mandatory for all students enrolled in second grade, except for those that
have already taken it before (and have already obtained a grade). Each working group, consisting of
three students, will prepare a seminar (which consists of a written manuscript and an oral presentation)
on a topic assigned at random from among those proposed by the teachers of the subjects participating
in this activity. Each interdisciplinary work is considered linked (see impact assessment of the activity) to
the subject that assigned the topic. A tutor will be assigned to each working team whose task will be to
supervise the work to be done. To do so, there will be scheduled a series of regular meetings with the
tutor throughout the course. At the beginning of the course the dates on which such meetings to follow-
up the work should take place will be published, as well as the date on which the final work should be
submitted and the documents handed in. A co-tutor will also be assigned who will review the final version
of the work presented. Each work will be presented orally by all members of the group for 30 minutes.
The presentation will be attended by all students of the course since attendance is compulsory, and also
two teachers: the tutor's work and a second teacher will be attending. Both students and teachers will
participate in selecting the seminars that due to their quality and originality will be presented at the
Congress of Biology, in which the first and second degree courses in Biology will participate.
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EVALUATIONThe assessment of learning knowledge and skills achieved by students will consider all facets of it and
will essentially continuously throughout the course in order to detect possible shortcomings time student
and be able to advise and help in their task. It will be therefore very important teacher-pupil relationship
and knowledge on his part on the degree of learning achieved by students which will facilitated by
personal tutorials.
However, in order to give a numerical rating of the degree of knowledge and skills gained by the
student, will be carried out various tests that attempt to measure these from the various educational
activities developed. Thus:
A. Evaluation of the knowledge of theory.
It will assess the concepts worked in the theoretical sessions by performing two written tests and
qualifying independent of matter. These tests relate to:
A1. First test. It will assess the theoretical, and practical application thereof, for the first 14 agenda
items. Will be held during the examination period in January.
A2. Second test. It will assess the theoretical, and practical application of these corresponding to items
15 to 25 of the program. Will be held during the examination period of May-June.
The student is not present or does not exceed (compensable from 4 / 10) the first of these tests may
recover in the period May-June reviews.
The student does not exceed the subject in the first call but must have passed (at least 5/10) of any party
theory (A1 and/or A2), you keep the note of the theory adopted by the second call.
The combined value of these tests represents 54% of the final course grade (27% each test).
B. Assessment of knowledge and problem solving skills.
The note of section B (problems) will be obtained from two types of activities: a) active participation in the
problem classes (presentation of some of the problems that will be made during the class and realization
of learning controls) and b) realization of a written test after the completion of the classroom sessions
(January exam period). The student who is not present or does not pass it will be able to recover it in the
examination period of May-June (first call of the subject).
The participation grade will be worth 4 points and the written exam will be worth 16 points. The
joint value of the tests referred to this aspect represents 20% of the final grade of the subject.
To pass the subject, it is necessary to obtain a minimum grade of 4 in section B. In order to save the
note in section B for the second call, it is necessary to obtain a minimum grade of 5.
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C. Evaluation of the work and the capacity developed during the conduct of practical laboratory
work and computing.
It will assess the work done in the lab (the labs) and practical sessions in computer lab. The assessment
of this aspect will be based on the skills shown by the student to work in the laboratory or the sequence
analysis program and the memory present on the work done. For laboratory work will be presented a
report, while for work in computer room will be filled in questionnaires to be sent to the teacher after each
session. The value of this part shall be 16 points in the final course grade (10 laboratory work and 6
computing ).
Attendance at lab sessions is a prerequisite to pass the course.
D. Evaluation of the interdisciplinary seminar.
The grade obtained in interdisciplinary work will be 10% of the final grade of the course. The
interdisciplinary work tutor and the professor that will attend the oral presentation will all participate in the
evaluation of the this work (with a relative contribution to the activity grade of 60% and 40%, respectively.
The assessment of this activity includes both the scientific content covered and presentation, and the
students’ ability to communicate and transmit ideas and concepts will be particularly taken into account.
The papers selected for presentation at the Congress of Biology have an extra qualification, equivalent to
10% of the activity grade.
In the case the subject linked to the interdisciplinary seminar was not passed, the grade of the
interdisciplinary work will be saved for the following course.
In the event that the interdisciplinary work (which is mandatory) were not carried out, the student will fail
the subject linked to the interdisciplinary seminar (the subject taught by the tutor of the work who
suggested the theme), regardless of the grade obtained in the rest of the parts considered for evaluation
in the corresponding subject. Nevertheless if this grade were 5 or more out of 9, it will be saved for the
following academic course to be added to the grade obtained in the Interdisciplinary Seminar once this is
carried out carried out and passed.
If this subject were not the subject linked to the Interdisciplinary Work and this activity were not carried
out, in order to pass the course students will need to obtain a grade equal to or greater than 5 on a
maximum of 9.
F. Student portfolio.
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The student can get up to 10% extra on the final course grade by the valuation of the interest shown by
students in the subject and their degree of maturity in the field of biology, may make teachers
appreciated the assistance east to the personal tutoring and individual activities that have been
previously consulted with the teachers. As an example we can cite: the reading and critical analysis of
books on genetics, performing certain tasks proposed for theoretical work, attendance at seminars or
conferences.
Summary of the evaluation:
Part Punctuation
Retained for conv. 2 only if the
note in conv. 1 is greater than
or equal to :
A1. Lesson 1 a 14 up to 27 points 5
A2. Lesson 15 a 25 up to 27 points) 5
B. Problems up to 20 points 5
C. Practical work
(laboratory and computer
science)
up to 16 points
(10 lab. and 6 computing)
5
D. Interdisciplinariy seminar up to 10 points 5
E. Student portafolio
(voluntary)
up to 10 points (extra) 0
Other considerations:
To pass the course will be necessary to obtain a global score above 5 on 10 (50 points) and scores
greater than or equal to the equivalent of 4 out of 10 in paragraphs A1, A2, B and C.
The rating of the portfolio will be taken into account once passed the course.
In the May-June exam, it will not be possible to improve the grade in sections A1 and / or B if they have
already been approved (5 out of 10) in the test accomplished in January.
Laboratory and bioinformatics notes (section C, practices) or above 5 (of 10) obtained during an
academic year will be saved for the calls of the three following academic years.
Students who do NOT report to any part of the final examination (theory and / or problems) and do not
pass the course, include the note not present in the record.
It is recalled that it is NOT POSSIBLE TO WAIVE the qualifications above 5 obtained, both in the
evaluation of the different evaluation tests and of the documents submitted for the same (exams, reports
...), as well as in the valuation of the participation In the classroom teaching activities (laboratory,
problems, seminars ...).
Second call:
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Students who fail the subject in the first round of the course (May-June), they save the note to the
second round (July), either the sections on knowledge of theory independently (A1 and/or A2), the
resolution problems (B), practical work (C) and / or interdisciplinary work (D), where they have passed (5
/ 10).
Please note that to pass the subject in the second round of the course, students must have passed the
practical work (section C).
REFERENCES
Basic - Pascual, L i Silva, F. (2018). Principios básicos de genètica. 1ª edició. Ed. Síntesis. ISBN
9788491711063 - Pierce B. (2016) Genética. Un enfoque conceptual. 5ª edición. Ed. Médica Panamericana. ISBN: 978-
84-9835-392-1 - Klug, W., Cummings, M.R., Spencer C. A. y Palladino M.A.(2013). Conceptos de Genética. 10ª
ISBN: 978-950-06-1448-1 - Benito, C. 141 Problemas de Genética. (2015). 1ª edició. Ed. Síntesis. ISBN 9788490772195 - Ménsua, José L. (2003). Genética. Problemas y ejercicios resueltos. Ed. Pearson.
ISBN: 9788420533414. - Griffiths;, A.J.F.; Wessler, S.R.; Carroll, S.B. and J. Doebley (2012) . Introduction to Genetic
Additional - Sociedad Española de Genética (http://www.segenetica.es/ ). Visitar el apartado de docencia: hay
lecciones, problemas y recursos multimedia - DNAi.org (DNA interactive). En inglés (http://www.dnai.org/index.htm) - DNA from the beginning. En inglés. (http://www.dnaftb.org/). - S c i t a b l e . A C o l l a b o r a t i v e L e a r n i n g S p a c e f o r S c i e n c e . G e n e t i c s .
( h t t p : / / w w w . n a t u r e . c o m / s c i t a b l e / t o p i c / g e n e t i c s - 5 ) . - Departamento de Genética (http://www.uv.es/genetica)
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ADDENDUM COVID-19
This addendum will only be activated if the health situation requires so and with the prioragreement of the Governing Council
1. Contenidos
Dado que las actividades prácticas y de resolución de problemas han sido impartidas y evaluadas como
estaba inicialmente programado y que la docencia de la parte teórica se ha completado con algunas
sesiones no presenciales, se mantienen los contenidos de la asignatura.
2. Volumen de trabajo y planificación temporal de la docencia
Se han mantenido las actividades inicialmente programadas en la guía docente, aunque se ha
procedido a una reordenación de la planificación temporal, coordinada entre todas las asignaturas, al
objeto de evitar solapamientos entre actividades de diferentes asignaturas. Las sesiones han sido
reubicadas y reorganizadas dando un poco más de tiempo como lo requieren actividades no
presenciales.
La impartición de algunas de las actividades presenciales de manera no presencial ha provocado un
cambio en la distribución del volumen de trabajo como se indica:
Clases de teoría 48
Prácticas en aula 22
Prácticas en laboratorio 10
Prácticas en aula informática 4
Tutorías regladas 3
Total 87 horas, 13 horas menos de presencialidad
Elaboración de trabajos en grupo 10
Elaboración de trabajos individuales 12
Estudio y trabajo autónomo 50
Preparación de actividades de evaluación 35
Preparación de clases de teoría 34
Preparación de clases prácticas y de problemas 22
Total 163 horas, 13 horas más de trabajo autónomo
3. Metodología docente
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La docencia presencial de clase (teoría, tutorías grupales y una sesión de bioinformática) han sido
sustituida por videotutoriales y apuntes complementarios a las presentaciones de los temas. La lectura
de los apuntes permite seguir la presentación de las clases. Se ha reforzado el asesoramiento a los
estudiantes mediante sesiones de chat y foros sobre los temas tratados.
Las tutorías personales son atendidas por correo electrónico.
La plataforma tecnológica utilizada es Aula Virtual y las herramientas:
Depósito de material para el autoaprendizaje
Chats y foros para la discusión de los temas y aclaración de dudas
Tareas y cuestionarios para la evaluación de las actividades
Si una persona no dispone de los medios para establecer conexión y acceder al aula virtual, deberá
contactar con el profesorado por correo electrónico en el momento de publicación de este anexo a la
guía docente.
4. Evaluación
Dado que las actividades prácticas de la asignatura ya han sido evaluadas o se evalúan de forma
continua mediante tareas que no requieren de presencialidad, se mantiene la ponderación de los
diferentes apartados de la asignatura que aparecen en la guía docente.
Se rebaja el criterio de compensabilitat de los apartados a partir de un valor de 3/10, es decir, los
apartados A1, A2, B o C de la asignatura podrán ser compensados por el resto si su valor es de 3 o
superior.
Las actividades de trabajo práctico de laboratorio y bioinformática (C) y de trabajo interdisciplinar (D)
son evaluadas de manera continua. Las actividades de contenidos teóricos (A1 y A2) y de resolución de
problemas (B) requieren de una prueba de nivel.
La prueba final no presencial constará de dos ejercicios, uno sobre la parte de problemas de la
asignatura para aquellos estudiantes que no la tengan ya superada y otro sobre la teoría (primera parte
por aquellos que no la tienen superada y segunda parte para todos). Estas dos pruebas se realizarán en
la fecha asignada mediante las herramientas on line disponibles en Aula Virtual.
Si por causas técnicas, debidamente justificadas, algún estudiante no puede realizar algún examen, se
estudiará la posibilidad de realizar una prueba alternativa que, en todo caso, será de tipo oral.
5. Bibliografía
La bibliografía necesaria para poder completar los contenidos impartidos en clase está accesible en aula
virtual.
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Se suben al aula virtual archivos multimedia sobre las clases de teoría y el uso de programas
informáticos para las clases prácticas.
Se mantiene la bibliografía recomendada en la guía docente. Esta bibliografía no es imprescindible para