CORSI DI AGGIORNAMENTO PER MMG CORSI DI AGGIORNAMENTO PER MMG Modena 12 aprile 2002 Modena 12 aprile 2002 Criteri decisionali fra Criteri decisionali fra Global Initiatives on Asthma Global Initiatives on Asthma (GINA) e (GINA) e Obstructive Lung Disease Obstructive Lung Disease (GOLD) (GOLD) Prof. Leonardo M. Fabbri Prof. Leonardo M. Fabbri Clinica di Malattie dell’Apparato Clinica di Malattie dell’Apparato Respiratorio Respiratorio
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CORSI DI AGGIORNAMENTO PER MMG Modena 12 aprile 2002 Criteri decisionali fra Global Initiatives on Asthma (GINA) e Obstructive Lung Disease (GOLD) Prof.
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CORSI DI AGGIORNAMENTO PER MMGCORSI DI AGGIORNAMENTO PER MMGModena 12 aprile 2002Modena 12 aprile 2002
Criteri decisionali fra Criteri decisionali fra Global Initiatives on Asthma (GINA) e Global Initiatives on Asthma (GINA) e
Third Quarter, 2000: Publication Date from 2000/07/01 to 2000/09/30
Search COPD NOT ASTHMA: All Fields.
Limits: All Adult: 19+ years, only items with abstracts, English, Clinical Trial, Human
Sort by: Authors (20 citations)
No star = Clinical Trial, One * = Randomized Clinical Trials (15 citations)
Two ** = Randomized Clinical Trials and Core Clinical Journals (7 citations)
ASSIGNMENTS, REVIEWER, PUBLICATION NUMBER
Peter Barnes, 8
Sonia Buist, 16, 17
Leo Fabbri, 14, 20, 10, 19
Yoshi Fukuchi, 5, 7, 10, 12, 19, 20
Bill MacNee, 1, 5, 8, 15
Romain Pauwels, 16, 17
Klaus Rabe, 2, 3, 4, 11, 14
Roberto Rodriguez-Roisin, 2, 3, 4, 11, 13, 18
Jan Zielinski, 1, 7, 10, 15, 19
GOLD REPORT – Section 4Page 32, left column, end of para 2,
ORIGINAL TEXT…. tract inflammation57-61. It is likely that
indoor air pollution derived from the burning of biomass fuels will prove to
have similar effects.
SUGGESTED REVISION…. tract inflammation57-61. It is likely that indoor
air pollution derived from the burning of biomass fuels will prove to have similar effects. Also bacterial colonization
contributes to the airway inflammation in patients with stable COPD. The
degree of inflammation also relating to the bacterial load and to the bacterial
species (Hill at et al, 2000). Consequences of such colonization
and enhanced inflammation on morbidity and lung function is not clear
Hill AT, Campbell EJ, Hill SL, Bayley DL, Stockley RA. Association between airway bacterial load and markers of airway inflammation in patients with stable chronic
bronchitis. Am J Med 2000 Sep;109(4):288-95
Levels of evidenceLevels of evidenceLevelLevel SourceSource
Classification by severityStageStage CharacteristicsCharacteristics
0 : At risk0 : At risk Normal spirometry. Chronic symptoms (cough, sputum),Normal spirometry. Chronic symptoms (cough, sputum),
I : MildI : Mild FEV1/FVC < 70%, FEV1 > 80% predicted with or without FEV1/FVC < 70%, FEV1 > 80% predicted with or without symptoms (cough, sputum) symptoms (cough, sputum)
II : ModerateII : Moderate FEV1/FVC < 70%, 30% < FEV1 < 80% predicted with or FEV1/FVC < 70%, 30% < FEV1 < 80% predicted with or without chronic symptoms (cough, sputum, dyspnea) without chronic symptoms (cough, sputum, dyspnea)
IV : SevereIV : Severe FEV1/FVC < 70%, FEV1 < 30% predicted or presence of FEV1/FVC < 70%, FEV1 < 30% predicted or presence of respiratory failure or clinical signs of right heart failurerespiratory failure or clinical signs of right heart failure
Bronchial biopsies from 2 asthmatics of similar Bronchial biopsies from 2 asthmatics of similar age and with similar degree of fixed airflow age and with similar degree of fixed airflow
limitationlimitation
Characteristics of patients with fixed Characteristics of patients with fixed airflow limitationairflow limitation