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Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor Lee Kong Chian School of Medicine Consultant ENT / Head & Neck Surgeon Tan Tock Seng Hospital
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Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Jul 08, 2020

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Page 1: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Considerations in

Oncologic Resection

(mandible & maxilla) Jeeve Kanagalingam

MA, FRCS (ORL-HNS), FAMS

Assistant Professor

Lee Kong Chian School of Medicine

Consultant ENT / Head & Neck Surgeon

Tan Tock Seng Hospital

Page 2: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Oncological Resection of the

Mandible

Routes of spread

Via dental sockets

/ pits

(preferential)

Direct invasion

through

periosteum

Via mental and

mandibular canals

Page 3: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Predicting mandibular invasion

All modalities of imaging

have their limitations

A combination of scans

e.g. OPG / Panorex and

MRI may give a better

yield

Mental numbness is a

very useful clinical sign

J. S. Brown, H. Lewis-Jones. Evidence for imaging the mandible in the management of oral

squamous cell carcinoma: a review. British Journal of Oral and Maxillofacial Surgery 2001; 39: 411 -

418.

Page 4: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Marginal or Segmental

Marginal

mandibulectomy – when

tumour is abutting but

not invading the

mandible

Segmental

mandibulectomy – when

tumour invades the

mandible

Page 5: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Does it matter?

Retrospective study of 111 patients undergoing either segmental or marginal mandibulectomy

Marginal if cortex involved or to achieve clear soft tissue margins

Segmental if deeply invaded mandible

Ranjan S Patel et al. The Prognostic Impact of Extent of Bone Invasion and Extent of Bone

Resection in Oral Carcinoma. Laryngoscope 2008; 118: 780 - 785.

Page 6: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Decision tree for mandibulectomy?

Patient factors

Height of mandible – the aged and the edentulous

Previous radiotherapy

Technical factors

Does tumour wrap around mandible making it difficult to achieve clear soft tissur margins?

Will a marginal mandibulectomy leave sufficiently strong bone?

Tumour factors

Does the tumour invade the mandible

Page 7: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Mandibulectomy

Page 8: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Oncological Resection of the

Maxilla

Understand the anatomy

of the maxilla and

associated structures

Understand the extent of

the tumour and its

behaviour

Decide on the extent of

maxillary resection

Decide on the surgical

approach

Ohngren’s Line

Page 9: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Anatomy

Page 10: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Anatomy

Page 11: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Imaging

Page 12: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Imaging

Page 13: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Approaches to the maxilla

Endoscopic

Per-oral

Combined

Lateral rhinotomy

(Moure’s)

Mid-facial degloving

Weber-Ferguson (WF)

WF with lynch extension

WF with Dieffenbach

extension

WF with supra and sub-

ciliary extension

Page 14: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Common facial incision

Page 15: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Resection of the maxilla

Medial maxillectomy

Subtotal maxillectomy

Infrastructure

maxillectomy

Total maxillectomy

Caldwell-Luc

Maxillary swing

Page 16: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Lateral rhinotomy (Moure’s incision)

Relevant anatomy

Angular vein

Medial canthal

ligament

Lacrimal sac and

nasolacrimal duct

Trochlea for the

tendon of the superior

oblique

Ethmoidal vessels

24, 12 and 6 rule

Inferior orbital nerve

Operative Otolaryngology. Bleach N et. al.

Page 17: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Lateral rhinotomy (Moure’s incision)

Headlight!

Tarsorrhaphy

Infiltration and nasal

decongestant

Plan incision carefully

Cut down to bone

avoiding angular vein

Elevate periosteum

with freers and blade

Operative Otolaryngology. Bleach N et. al.

Page 18: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Lateral rhinotomy (Moure’s incision)

If incision is extended along superior orbital rim, divide trochlea

Retract and protect orbit with malleable retractors

Work towards vessels, divide and ligate/cauterise

Divide nasolacrimal duct tangentially

Raise skin on face of maxilla to infraorbital nerve

Operative Otolaryngology. Bleach N et. al.

Page 19: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Anterior ethmoidal artery

(right)

Page 20: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Medial Maxillectomy

Page 21: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Medial Maxillectomy

Page 22: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Medial Maxillectomy

Page 23: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Medial Maxillectomy

Page 24: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Medial Maxillectomy

Page 25: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Medial Maxillectomy

Page 26: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Medial Maxillectomy – post op

Page 27: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Medial Maxillectomy – post op

Page 28: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Midfacial Degloving

Cannot reach tumours

with extension above

the level of the medial

canthus

Can be combined with

bicoronal flap

Suitable for young

children

Operative Otolaryngology. Bleach N et. al.

Page 29: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Midfacial Degloving

4 incision

1. Sublabial from one

maxillary tuberosity

to the other

2. Intercartilaginous

incisions

3. Full transifixion

incision

4. Vestibular incision

(stepped to avoid

stenosis)

Operative Otolaryngology. Bleach N et. al.

Page 30: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Midfacial Degloving

Operative Otolaryngology. Bleach N et. al.

Page 31: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Midfacial Degloving

Midfacial Degloving Approach for Malignant Maxillary

Tumors

ASHRAF S. ZAGHLOUL, M.D*; M. AKRAM

NOUH, M. and HISHAM ABD EL FATAH, M.D

Cairo University.

Page 32: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Infrastructure Maxillectomy

Tumours of the upper

alveolus

Often oral cavity SCCs

so are aggressive

Page 33: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor
Page 34: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor
Page 35: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor
Page 36: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Subtotal Maxillectomy

Removal of most of the

maxilla

Leaving some

suprastructure for orbital

support

Best performed via a

Weber-Ferguson incision

with Dieffenbach extension

Page 37: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Subtotal Maxillectomy

Page 38: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Subtotal Maxillectomy

Page 39: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Subtotal Maxillectomy

Page 40: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Subtotal Maxillectomy

Page 41: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Subtotal Maxillectomy

Page 42: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Subtotal Maxillectomy

Page 43: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Subtotal Maxillectomy

Page 44: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Subtotal Maxillectomy

Page 45: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Subtotal Maxillectomy

Page 46: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Subtotal Maxillectomy

Page 47: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Subtotal Maxillectomy

Page 48: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Maxillary Swing

For access to the

nasopharynx in salvage

nasopharyngectomy

Allow for enbloc resection of

paranasopharyngeal tissue

Page 49: Considerations in Oncologic Resection (mandible & maxilla)...Considerations in Oncologic Resection (mandible & maxilla) Jeeve Kanagalingam MA, FRCS (ORL-HNS), FAMS Assistant Professor

Sir Bobby Robson

(18 February 1933 – 31 July 2009)