Off.: Plot-36, Shramsafalya, RSC -11, Veer Savarkar Nagar, Thane (W) – 400606 Maharashtra (INDIA). Tel.: 91- 22 – 2582 8524, 0250-6454728/29 Telefax: 91 – 22 -2583 3896 Website: Email: [email protected] www.paanpharmatech.com Pharmatech Engineers Pvt. Ltd. PAAN Pharmatech Engineers Pvt. Ltd. PAAN RAPID MIXER GRANULATOR I. Salient Features for production scale ? ? ? ? ? ? ? ? ? ? Homogeneous binder distribution. Short batch time and reduce cleaning time. Maximize CIP effectiveness. Air purging system for both agitator. PLC based operating panel for precise control of process automation. A high-speed granulator is to assist blending of powder and to break the product to the granules of required size All moving parts of the machine are totally enclosed. The machine cannot be started unless and until the mixer cover is properly closed. All contact parts are made out of SS316. Geometrically bowl and impeller shall be same so as to set all mixing parameters as per R&D version. DESCRIPTIONS The PAAN'S RMG working principle is based on two decisive factors essential for the mixing systems. Rapid Mixer Granulator was developed in close co-operation with pharmaceutical industry. With the help of RMG wet sifting is generally no longer necessary. After the mixing of the dry components, subsequent wet granulation occurs (without transfer of dry mixture) producing loose granules in RMG. Better mixing and closed control of granule size leads to faster tableting speeds with improved quality and least rejections. Dry mixing and Wet Granulating in the same bowl in only few minutes. The entire operation including discharge is fully automatic. Spinning close to the bottom of the mixing bowl. The impeller sets the entire mixture in a whirling-rising tumbling motion ensuring a quick and even distribution of all dry components, which leads to an even wetting of every granule. The large lumps occurred during wet mixing are broken up, by the strategically located chopping tool rotating at 1440/2880 RPM. The mix can be discharged with the impeller through the outlet flush to the bottom. The mixing tool is easily removed. II. Salient Features for Lab scale ? ? ? ? ? ? Portable self contained unit, Process flexibility. Quick changeover for all parts without any tools. Interchangeable bowl facility, speed regulator for chopper and main anchor. Optional- I) Solution addition facility, II) Jacketed. Geometrically well engineered shape and beater. PLC control system in R&D unit which will be very easy for scale up the production.(all parameters are well defined at R&D level). MODEL C-BD 20 C-BD 30 Product inlet DIA 10'’ 12’’ Throut inlet DIA 8’’ 12’’ Product outlet DIA 12’’ 20’’ Screen Round hole type Round hole type Impeller Standard Standard Drive 5 kw 1500 rpm motor with gear 10 hp 1100 rpm motor with gear Output (kgs / hrs) 100 -1200 250 - 3000 Discharge Quick release, swing away, collar at discharge end for easy bag fixing, grid mesh for added safety protection. Spindle Assembly Sanitary pharmaceutical GMP grade, pre lubricated sealed bearing viton O-ring, two shaft seal & single leap seal in SS 316 casing it can be used for Vacuum application. MOC Contact parts SS 316 & Non contact parts Ss304 Finish Non contact parts -150 Grit (RA 1.06) Contact parts- 300 Grit (RA 0.53) TECHNICAL SPECIFICATION FOR BOTTOM DRIVEN Cone Mill is suitable for dry granulation & wet granulation. To satisfy the need of size reduction, conical screen mill concept is developed. The key to the co-mill's superior performance is, the engineered combination of low velocity operation and the highly evolved design & geometry of the conical screen & impeller.(i.e. milling components) DESCRIPTIONS CONEMILL BOTTOM-DRIVEN BOTTOM DRIVEN HSMG (RMG) ? ? ? ? ? ? ? ? ? ? ? ? ? F so bet n f re a l t sa ro ssem ully cu t miza l o ma y dif e nt pp ica ion ndp ce s tr a s. p dd i nal w i h re y t at n ro c Low s ee es g lo ing for n e ntl gen le c ion o the p du t sln i t m ail ra l ri re u ti g n Op imu p rtceg nu a ty. Hi hc a i sc sse ih u t dp u g ap cite on i t nt, hg -q aliyen rod ct o h e o c le t re ci n a sn ie Lw eat gen rati n, ex e l n for size du to of he t e sit v pou i n u a a r d ct n de se h mid re . Ca v d s , oc kn a ig olm nbeo er o edn ho i g &j mmn pr be . o ie e, ii u L w nos lev l l d t ni n na fri n mnm m ro ow us- e vro me t l e dly p duct ls o s. g e p ut te tio c s t p r c n Ne ligibl rod c re n n with on isten erfo man e a d p t y re ea abilit . Es p rai n s la, o i te n , q s e a y for o e to - ea y ce n l w man na ce uick cre n a v ch ngeo er. l bl y – Ca ct n ail i tr ti n a aa o Sca a i it pa iies a d p rtce size ds ibu o re sc l ble t l rg ui a er n ts. ag di ete R s 0 h c a a L r e feed am r e ults in to 5 % hig er ap city th n ov t a ie c n en ion l mach n s. S fp d ta e / c sn a uai nat r izingo ro uc ft r FBD pro es i gwet gr n l to f e RMG. l A se &i p e em ehg g q ym A l PA N i ves m ell r ar ad i h rade ualit aterial. bs u ts a t e re n o i i te d For e t res l g p be we n sc en a d r tor s ma n ne . FEATURES ? ? ? ? Gr r ou e zi g & si f w anulation of d y powders for s l bl s, si n Uniform zing o et ulation actu gran in tablet manuf ring. S uci an ng d pr ize red ng d milli of wet or soake oducts to produce liquid ih et nde ar w t W suspe d p ticulates. ge & e l nding e is em Lump-free homo neous w t b e to pr c e size requir ents. i , ve e nt Reducing d fficult, sticky heat-sensiti agglom rates i o pieces, m ntinu e ive cru bs or powders of uniform size, co ously without exc ss at i or scr a he bu ld-up een block ge. T P CA A PL CATI S YI L P I ON Compliance certificates & DQ, IQ, OQ. Documents are available to make your validation process easier. Documentation The Bottom-driven PAAN CONEMILL is based on the same technology as the Top-driven. It has the same capabilities as the Top-driven PAAN CONEMILL with some additional benefits. It has a compact, inline design, which allows for easy integration into processing environments where head room is limited. It is available in three models which are scalable in capacity up to 1800 kg/hr. PRODUCT DESCRIPTION