Computational Methods and Advanced Materials Simulations of Biomedical Devices FEA of Self-Expanding Braided Wirestent Geometrical Modeling Cardiovascular/Gastroenterical /Pulmonary Device (i) Creation of a base module of two crossing wires; (ii)Extending the base module with a translated copy; (iii)Replicating the base module in both directions of the base plane; (iv)Rolling the resultant grid into a cylinder Stent deployment Simulation Reality Stent elongation: Stress analysis 3 different materials Phynox, Nitinol, Stainless Steels Finite Element Analysis Filter diam:4 mm Filter diam:6 mm Filter diam:8 mm 60% covered 70% covered 80% covered 6 struts 10 struts Nitinol Embolic Protection Filters: Design Investigation by Computational Tools Geometrical Modeling Cardiovascular Device Finite Element Analysis Simulation Experimental validation Filter deployment μCT scan X Y Z Parametric CAD Model Markers Struts Membrane Model parameters: Filter diameter, Filter length, Strut diameter, Strut number / distribution, Strut shape, Marker size, Covering percentage μCT scan Simulation Filter-vessel interaction Contour-ability Gap Nitinol Laser-cut Stents: The Current Trend of Peripheral Stenting Experimental Tests and Material Characterization Cardiovascular Device Finite Element Analysis Crush Tests Constitutive model implementation: “user material subroutine” (Abaqus) Spinal Vertebrae Spacer: A Medical Application of Shape Memory Effect Device objective: substitution of damaged intervertebral disc Shock absorber & motion unit Maintenance of inter-vertebral separation No nerve compression Spine compression / rebounding during activities Gravity resitance on head and trunk during prolonged sitting and standing, Spinal segment flexibility, rotation, and bending on side Ortopaedical Device Due to symmetry, only ¼ of the device is simulated • Device is compressed in martensitic phase, assuming a reduced shape [ to help device insertion ] .Once positioned in body, it recovers original expanded shape by thermal recovery (shape memory effect) and starts to work opposing force to spinal compressive load • Compare different Ni-Ti spinal spacers during implant and physiological loading Finite Element Analysis G. Attanasi A , F. Auricchio A , M. Conti A , S. Morganti A , A. Reali A , U. Stefanelli B Contact: Prof. F. Auricchio Email: [email protected] Tel.: +39 0382985476 A Università Degli Studi di Pavia Dipartimento di Meccanica Strutturale Via Ferrata ,1 C Consiglio Nazionale delle Ricerche Istituto di Matematica Applicata e Tecnologie Informatiche Via Ferrata ,1 B EUCENTRE European Centre for Training and Research in Earthquake Engineering Via Ferrata ,1