Colorectal cancer is Malaysia's second largest killer Every year five million people died, due to stroke in Malaysia Expert: Chinese is high-risk group.

Colorectal cancer is Malaysia's second largest killer

Every year five million people died, due

to stroke in Malaysia Expert: Chinese is high-risk group of

colorectal cancer

• Also known as dried plum, mainly produced in California and France

• Plums dehydrated in hot temperature (85-90 ) for ℃18 hours continuous, after which they are called prunes. Prunes are further minced, filtered, and processed to produce prunes concentrate juice or prune sauce

• A Comprehensive food: high in antioxidant, high fibre -relieves constipation, reduce damage from free radical oxidation.

• Convenient for busy lifestyle, easy to carry and high in nutritional value

• One of the secret weapon for longevity & Constipation

What is Prunes？

Optimistic attitude towards life Warm and happy family Hospitable habits Highly developed medicines

Longevity

Secrets

Of Caucasians

2000 years ago, already know prunes rich in nutrients

Do you know？

There are lots of European plum trees growing tall and healthy on the mountains in the Caucasus region between the Black Sea and the Caspian Sea. Plum trees blossom in the spring with white flowers, and in summer they bear sweet purple fruits.

It is believed that plums are fruits of immortality. Coincidentally, those who eat them do enjoy longevity indeed.

Click for more information!

Minerals（ Calcium、 Ir

on、 Potassium、 Boron）

Fiber

Folate

Vitamins（ A/B complex/C）

Cholesteroland Fat

free

High in antioxidants

ORAC

• Natural prunes from free-pollution farm in California, Japan technology

• With 6 types of mixed berries  (Red grape/white grape/yumberry/ blueberry/raspberry/ mulberry)

• Produced by GMP factory with advanced technology

• No added colouring/sugar/additives/preservatives

• 36,600 ORAC unit of antioxidants, high dietary fibre

THE PERFECT MATCHWell3 Prune Berries

1Natural Prunes from free pollution plantation in California

2Mixed berries concentrate juice (red grape / white grape / blueberry / yumberry / raspberry / mulberry)

Concentrated berry juice Function

Red GrapeWhite Grape

High resveratrol*, polyphenols have strong antioxidant and anti-inflammatory properties.Regulate blood pressure, improve cardiac function, prevent atherosclerosis and stroke, anti-allergic, promote lung health and beauty.

* their roots have properties that can help fight cardiovascular diseases

Blueberry Improves eyesight and cardiovascular function. Balances blood sugar, improves brain function and memory.

Bayberry Rich in vitamin C and organic acid and helps digestion, increases immunity and improves skin texture.

Raspberry Antibacterial. Rich in vitamin C, high in antioxidants and low glycemic index, suitable for diabetics.

Mulberry High in iron. Improves blood circulation, anti-inflammatory, protects eyes, good for hair darkening and beauty

Superfruit

3 1. High antioxidant2. High nutritional value3. Promotes gastrointestinal

motility

Prunes Nutrients Function

Antioxidants• High antioxidant-8,059µmol TE/100g • Anti-aging, slow s brain aging• Protects cells, eliminates free radicals and prevents cancer• Chlorogenic acid and proanthocyanidins contain high antioxidant index

Vitamin A• Protects eyesight• Maintenance of epithelial cell function; for glowing, soft and delicate skin,

wrinkle prevention effect• Maintenance of hair• Helps bone and tooth growth

Vitamin C • Promotes bone growth, muscle development• Prevent s hardening of the arteries, protects teeth and helps iron absorption

Folate• Prevents heart disease and stroke. (particularly important for the elderly with

low folate level)• Prevention of megaloblastic anemia and leukopenia• Pregnant women often take folate to prevent underweight baby, premature

birth, infant with cleft palate (cleft lip) and other congenital malformations

Potassium• Maintains muscle elasticity• Maintains body electrolyte balance• Helps nerve impulses as well as energy release from metabolic process

Iron• Prunes are rich in iron; ranked top ten and has 11 times more than apples• Facial lustre, glow, and can increase physical strength• Iron is crucial for pregnant women, lactating women and infants

Boron • Helps in the absorption of calcium to prevent osteoporosis

Dietary fiber • Promote gastrointestinal motility, intestinal cleansing• Commonly known as "constipation inhibitor“

Top Ten Foods rich in Iron:

1. Dried fruit (prunes, raisins)2. egg yolks3. Dark/ green leafy vegetables (spinach, kale)4. red meat5. cereals and grains6. oysters, clams, scallops7. turkey or chicken offal8. Beans9. liver10. Artichoke

Source:

Jadual

High Antioxidant

Free radicals are normally caused by aging and external factors, such as smoking, pollutions and sun exposure.We are fine as long as there’s enough antioxidants in our body. Otherwise, free radicals will attack, and ultimately destroy healthy body cells, causing damage and leading to life-threatening diseases such as:

- Immune dysfunction- Cancer- Cardiovascular diseases- Cognitive impairment- Deterioration of eyesight- Dementia or Alzheimer's disease - Sagging skin, systemic aging

Source : US Department of Agriculture

Malaysian Dietary Guideline

• USDA recommends a daily intake of at least 3000 ORAC units to maintain metabolic balance.

Comparison of ORAC value in selected fruits

What is ORAC?

Source: http://www.brunswicklabs.com.cn/

F irst Inventioni

First developed in 1992 by Dr Guo Hua Cao from U.S. National Institute of gerontology and assisted by Dr. Ronald L. Prior.

It’s an acronym for Oxygen Radical Absorption Capacity

the HIGHER the ORAC value，the STRONGER the antioxidant’s capacity to inhibit free radicals.

1 sticks of Well3 Prune Berries

(10g)

31 times

14 times

9 times

3 times

Antioxidant Index

OR

OR

OR

Anthocyanins and phenolic acids are the phytochemicals contained in prunes.

Neochlorogenic acid and chlorogenic acid are phenolic acids found in abundance to help inhibit oxidation of low-density lipoprotein (LDL) , and

Reduce Heart Disease Morbidity rate.

Research reports

Prunes antioxidant function

Series10

0.5

1

1.5

2

2.5

Before After 4 weeks

4 weeks after stopping eating

CREATOL(Oxidative stress

markers)

Series1240

260

280

300

320

340

360

8-isoprostane(Oxidative stress

markers)(Mg/day) (Pg/day)

Before After 4 weeks

4 weeks after stopping eating

Prunes antioxidant function

Series1

0

10

20

30

40

50

60

70

Cancer Rat(%)

Source: Shimizu M,et al : J Toxicol Sci.1999 Dec;24(5):433-9

Normal daily diet

Normal daily diet + chlorogenic acid

Prunes antioxidant function

Series10

20

40

60

80

100

120

Series10

20

40

60

80

100

120

Prune Extract(mg/ml)

Gastric Cancer

number of cells(%)

*p<0.05 **p<0.01 vs.control

*

**

**

**

Colorectal Cancer

0.0 0.1 0.3 0.0 0.1 0.3

Series10

20

40

60

80

100

120

140

160

180

Prune Extract(mg/ml)

Number of cells(%)

*p<0.05 **p<0.01 vs.control

0.0 0.1 0.3

Normal cell

Prunes antioxidant function

Constipation Inhibitor

Prunes with mixed berries are high-fibre food, it supplies essential soluble and insoluble fibres to our body.

According to the American Institute for Cancer Research, eating a high-fiber diet can reduce the risk of bowel cancer.

Soluble fibre (pectin)

Insoluble fibre

Sorbitol

Reduces blood cholesterol level and blood glucose level

Laxative – soothes bowel

combines with water, to soften stool and promote healthy bowel movements

Constipation inhibitor

• One prune contains 0.7 grams of dietary fibre (about 7%), and four times more than an apple

• Prunes contain natural loose stool laxative ingredient-Dihydrophenylisatin, to assist muscle contraction, soften stool & ease excretion

Published in the 44th Fukuoka, Annual Meeting of Japanese Society of Clinical Nutrition

Prune juice Prune juice Water Water

(320g/day) (160g/day) (320g/day) (160g/day)

Frequency/day 0.9±0.2 1.1±0.7 0.6±0.2 0.5±0.2

Faecal form 2.4±0.6 2.2±1.0 1.7±0.7 1.2±0.6

Faecal softness 2.4±0.6 1.1±0.7 1.6±0.7 0.5±0.2

*

*A healthy Malaysian (> 2 years) daily intake is 20-30 grams of fibre.Adult male: 38g / day; adult female: 25g /day

Dietary Fiber 2 Banana

3 Slices papaya

3 Apples

Half a pumpkin

170g vegetables

4 Tomatoes

2Stick Well3 Prune Berries

Source: Malaysian Foods Composition Database, Nutrition Society of Malaysia

OR

OR

OR

OR

OR

Other functions

- Reduce cholesterol- Prevent hypertension/stroke- Prevent osteoporosis- Help bone metabolism- Inhibit bacterial growth- Improve beauty

Reduce Cholesterol

Reduce cholesterol

• Prunes have cholesterol-reducing effect

• Bad cholesterol* in blood and bile acids in faeces are obviously reduced, and 20% increament in stool volume**

American Journal of Clinical Nutrition

* LDL, low-density-lipoprotein cholesterol** Subjects consecutively took 12 prunes daily for eight weeks

Constipation Savior

Prevent hypertension/stroke

Prevent hypertension/stroke

Potassium is a very important substance to maintain normal activities in body cells, tissue and organs. It is responsible for the transportation of nutrients into cells and waste out of cells, helps muscle contraction, reduces the risk of recurrent kidney stones, reduces high blood pressure or stroke risk and prevents bone loss caused by agieng.

Concentrated Prune Essence(55g)

Sweet potato(100g)

Banana(120g)

Spinach(70g)

Fermented soy(50g)

pomelo(200g)

Green Pea(50g)

Kiwi(60g)

Orange(100g)

Broccoli(40g)

Amount of Potassium in Foods (mg)

Ratio of potassium and sodium in urine

Before After 4 weeks

4 weeks after stop eating

P < 0.05 P < 0.05

U.S. FDA says that eating foods low in sodium and potassium (at per serving at least 350 milligrams of potassium and less than 140mg of sodium) such as prunes can reduce the risk of high blood pressure and stroke.

Prevent Osteoporosis

Prevent Osteoporosis

Prunes contain a variety of natural compounds eg. organic acids, calcium, magnesium, phosphorus, vitamin K, copper, boron and can also maintain bone health.

Calcium, magnesium, phosphorus

Essential element to strengthen bones

Organic acids Enhance calcium absorption

Copper Facilitates bone formation

Vitamin K Increases bone density and reduces the incidence of fractures

Boron Regulates mineral metabolism, optimises hormone level and control the loss of calcium during urination

Source: Critical Reviews in Food Science and Nutrition 41(4), 251(2001)

Prevent Osteoporosis

Subject: postmenopausal women consecutively consume suffi cient calcium and vitamin D for 90 days, while taking 8-10 prunes with water, with the following results:

• Prunes is more effective than hormone therapy and other drugs in reducing body's bone loss

• Effectively rebuild bone osteoporosis

• Scientific evidence showed that anti-bone loss mechanism is related to the high antioxidant capacity

Unprocessed fresh plums do not have such effects

• Chairman of the Department of Nutrition, Food and Exercise Sciences, Florida State University

• World’s expert in bone health

Dr. BAHRAM H. ARJMANDI

Inhibit Pathogenic growth

Quinic acid can acidify urine so that pathogenic cannot grow, and resists pathogenic adhesion so that pathogenic cannot feed on the urethra, thus preventing urinary tract infection.

6:00 7:00 8:00 9:00 10:00 11:00 12:004

4.5

5

5.5

6

6.5

7

7.5

8

Consumed prune

Didn’t consume prune

The 3 rd Congres of Japanese Society of Nutrition and Food Science. (2003)

Inhibit pathogenic growth

Concentrated prune essence

Prune

Bilberry

Kiwi

Plum

4.28

Amount of quinic acid in fruits(g/100g)

Source: ITE Letters on Batteries, New Technologies & Medicine, 4, 639 (2003)

Improve beauty

- Antioxidants can slow or prevent the skin cells from damage caused by free radicals.

- Vitamins such as A and C, can help protect the skin from sun damage, thus preventing ageing, dull skin and wrinkles.

- Prune is rich in natural compounds that can promote growth of skin cells, help the skin healing process.

- Promote healthy bowel movement, reduce constipation, develop a non-toxic body , with an inner glow of healthy skin.

FAQ

1. Is Well3 Prune Berries a medicine/drug?No, Well3 Prune Berries is a natural supplement, it does not contain any chemical substances. It can replenish our body's nutrients and minerals, along with ANT concept of cleanse, restore, build, protect. 2. Well3 Prune Berries is suitable for:

3. Can pregnant women consume Well3 Prune Berries? Pregnant women can take Well3 Prune Berries safely. It contains iron, calcium, fibre and other nutrients which can help enhance foetal and mother’s health. Generally, pregnant women are accustomed to suffer from constipation, and Well3 Prune Berries can help them to relieve constipation. 4. Is there any other method to consume Well3 Prune Berries instead of taking it directly? You can use it as a spread, or natural seasoning in cooking baby food, ice cream, cake, etc.

Q & A

• Children – supply complete nutrients, promote healthy growth

• Pregnant women – Enhance essential nutrients for mothers during pregnancy and after delivery.

• Elderly – rich in calcium to help prevent osteoporosis• Anaemia patients – Helps in heme synthesis and prevents

anaemia

• Alcoholics – Helps in breaking down alcohol and reducing the effect of copper in body.• High blood pressure patients – Prunes with high potassium, low sodium, is very suitable for

them• Constipation patients – High fibres can improve bowel movements, excretion, alleviate

constipation and prevent haemorrhoids• Vegetarians – Best choice for vegetarians for source of iron.

Price list

RP MPRM90.00RM108.00

CV : 10

30 sachets x 10g / box

RP MPRM420.00RM504.00

CV : 50

30 sachets x 10g x 5 boxes

Recommended intake of atleast two sticks per day.Can be directly consumed or with 100 ml water (room temperature). Of course, you may also add it into your meals.

Add Prune Berries for better taste!