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Coimbra University Hospital Centre Orthopaedic Department Director: Prof. Dr. Fernando Fonseca Wrist Arthrodesis Clinical and Ultrasonographic Trial João Pedro Oliveira Sara Serra António Néri Berlin - 23 th of May 2012
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Page 1: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

Coimbra University Hospital Centre

Orthopaedic Department Director: Prof. Dr. Fernando Fonseca

Wrist Arthrodesis Clinical and Ultrasonographic Trial

João Pedro Oliveira Sara Serra António Néri Berlin - 23th of May 2012

Page 2: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:
Page 3: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

DISCLOSURE OF INTEREST

Nothing to Declare

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Page 4: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

INTRODUCTION

“Wrist arthrodesis results in a high degree of patient satisfaction and predictable pain relief in most patients. Most patients are able to return to gainful employment, many without impairment. Successful fusion rates have been reported in the vast majority of patients overall. Activities that require forceful gripping with the hand in a fully pronated or supinated position also may be difficult to accomplish. The most common indication for a wrist arthrodesis is advanced symptomatic arthritis secondary to a degenerative, post-traumatic, inflammatory, or postinfectious condition. Various techniques have been described for achieving a successful arthrodesis. The type of operative technique used depends on the underlying condition, quality of bone, presence of bi-lateral disease, condition of the remaining joints of the involved extremity, and surgeon's preference.”

Wrist Arthrodesis. Hayden RJ, Jebson PJ. Hand Clin. 2005 Nov;21(4):631-40. Review.

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Page 5: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

OBJECTIVES

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Primary endpoint: Evaluate the functional outcomes of wrist arthrodesis in patients with advanced symptomatic inflammatory or degenerative arthritis.

Page 6: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

METHODS

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Comparative and Retrospective Study Analysis Level of evidence: III

Total Wrist Arthrodesis between 1999 and 2009;

Clinical, Radiological and Ultrasonographic evaluation;

SPSS Statistics Software Version 17.0 for Windows.

Differences were deemed to be significant at p < 0.05

Exclusion Criteria :

- Tumor resections (OGCT); - Open fracture (2nd step)

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METHODS

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Functional evaluation:

- Visual Analogue Scale (VAS): [1-10]

- The Disabilities of the Arm, Shoulder and Hand Score (DASH) ): [0-100]

Am J Ind Med. 1996 Jun;29(6):602-8. Erratum in: Am J Ind Med 1996 Sep;30(3):372.

- Buck-Gramcko and Lohman Score System for Wrist Arthrodesis (BGL) ROM of fingers and forearm;

Functional use of the hand;

Pain;

Grip power;

Subjective evaluation Buck-Gramcko, D. & Lohmann, H.: Compression arthrodesis of the wrist, in Tubiana, R. (ed.). The Hand, 1981, 723

Excellent 9-10

Good 7-8

Satisfactory 5-6

Poor < 5

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BASELINE

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Population : 38 patients (7 bilaterally) n= 45

n= 25 Inflammatory Rheumatic Disease (IRD) n= 20 Remaining Cases (RC) IRD RC P-value

Age (Surgery) 49,9± 9,3 50,2± 18,8 0,948

Gender (Female) n= 24 (96%) n= 12 (60%) 0,030

Follow-up (Years) 6,1± 2,6 3,2± 1,4 0,000

Laterality (Right) n=16 (64%) n= 9 (45%) 0,200

Dominant Arm n= 15 (60%) n=13 (65%) 0,731

Page 9: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

BASELINE

Wrist Arthrodesis Clinical and Ultrasonographic Trial

0

5

10

15

20

25

Rheumatoid Arthritis

Psoriatic Arthritis

96%

4%

IRD

Surgical Indication

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BASELINE

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Surgical Indication

0

2

4

6

8 25 %

40 %

15 % 20%

RC

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BASELINE

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Surgical Technique

0

2

4

6

8

10

12

14

16

18

20

Mannerfelt AO/ASIF plate Colonna

52%

44%

4%

95%

5%

IRD RC

Page 12: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

RESULTS

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Post-Op

IRD RC p-value

Bone Union (Months) 3,3± 0,9 2,9± 0,8 0,228

Material Extraction n=5 (20%) n= 5 (25%) 0,481

Postoperative complications n= 3 (12%) n= 2 (10%) 0,832

Pull Out : n=1 (RC)

Pseudarthrosis : n=1 (RC)

Tendon Rupture : n=2 (IRD)

Tenosynovitis : n=1 (IRD)

Page 13: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

RESULTS

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Ultrasonographic Evaluation IRD Group

Local synovitis : n=2 (8%)

Mannerfelt: n=1

Plate: n=1

Extensor Tenosynovitis: n=2 (8%)

Plate: n=2

16% of US alterations All were of low intensity and without inflammatory activity identified by power-doppler signal

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RESULTS

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Functional Outcomes

IRD RC p-value

Pronosupination (80-100%) n=15 (60%) n= 15 (75%) 0,204

VAS at rest 2,0± 0,3 1,5± 0,7 0,832

VAS in activity 4,0± 0,6 2,5± 0,3 0,072

DASH Score 22,4± 5,6 13,0± 6,2 0,153

Page 15: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

RESULTS

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Functional Outcomes: BGL Score System

0

2

4

6

8

10

12

DRI RC

n IRD RC

Excellent or Good 8

(32%) 15

(75%)

Satisfactory or Poor 17

(68%) 5

(25%)

p= 0,005 12%

25% 20%

50%

20%

15%

48%

10%

Page 16: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

RESULTS

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Functional Outcomes: VAS Pre and Post-operatively

0

1

2

3

4

5

6

7

8

IRD RC

8

6,5

2 1,5

Pre-Op. Post-Op.

p= 0,578

Page 17: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

RESULTS

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Return to Work

YES

IRD n=14 (56%)

RC n=18 (90%)

p= 0,013

Page 18: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

DISCUSSION (1)

Wrist Arthrodesis Clinical and Ultrasonographic Trial

“Old Techniques” – Good Outcomes

Colonna

Mannerfelt

Is there a place for this procedures ?

Page 19: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

DISCUSSION (2)

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Postoperative – Cross Match

n= 5/5 complications

n= 3/4 US alterations

The Importance of the Plate

Design!

Plate

Page 20: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Would be wrist arthroplasty a better solution?

Case selection

Economy

Long Term Results

Function

DISCUSSION (3)

Page 21: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

CONCLUSION

Wrist Arthrodesis Clinical and Ultrasonographic Trial

IRD-US: Low intensity and without inflammatory activity

Time for bone union and post-op. complications

VAS / DASH / Pronosupination

RC group

- Excellent or good BGL outcomes, p<0,05 - Higher number return to their work, p<0,05

p>0,05

Page 22: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

OUR MESSAGE

Wrist Arthrodesis Clinical and Ultrasonographic Trial

Wrist arthrodesis:

Very effective

Encouraging functional outcomes and pain relief levels

Patients with and without inflammatory

rheumatic disease.

Page 23: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

Thank you...

Page 24: Coimbra University Hospital Centre - SNSrihuc.huc.min-saude.pt/bitstream/10400.4/1437/1/Wrist Arthrodesis.pdf · Coimbra University Hospital Centre Orthopaedic Department Director:

Save the Date Wrist Arthrodesis

Clinical and Ultrasonographic Trial